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Article ; Online: Invited Commentary.

Saint, Lindsey L

2017 Volume 104, Issue 5, Page(s) 1562–1563

Language	English
Publishing date	2017
Publishing country	Netherlands
Document type	Journal Article ; Comment
ZDB-ID	211007-6
ISSN	1552-6259 ; 0003-4975
ISSN (online)	1552-6259
ISSN	0003-4975
DOI	10.1016/j.athoracsur.2017.05.058
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Article: Incomplete coronary revascularization: a cautionary tale.

Saint, Lindsey L / Melby, Spencer J

Journal of thoracic disease

2017 Volume 9, Issue 3, Page(s) E264–E265

Language	English
Publishing date	2017-04-27
Publishing country	China
Document type	Editorial ; Comment
ZDB-ID	2573571-8
ISSN	2077-6624 ; 2072-1439
ISSN (online)	2077-6624
ISSN	2072-1439
DOI	10.21037/jtd.2017.02.69
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Article ; Online: Clotting Propensity in Trauma Patients According to Marijuana Use: A Descriptive Analysis.

LoPolito, Andrew / Mourabet, Tala / Syed, Huda / Brown, Catherine T / Saint-Fort, Launick / Horst, Michael A / Perea, Lindsey L

The American surgeon

2023 Volume 89, Issue 7, Page(s) 3263–3266

Abstract: Marijuana use has been reported to promote hypercoagulable states among trauma patients, particularly respecting venous thromboembolism (VTE), a major contributor to morbidity and mortality in patients sustaining traumatic injury. We sought to ... ...

Abstract	Marijuana use has been reported to promote hypercoagulable states among trauma patients, particularly respecting venous thromboembolism (VTE), a major contributor to morbidity and mortality in patients sustaining traumatic injury. We sought to investigate this further through a retrospective, single institutional study performed from January 2018 through June 2021, utilizing data from patients presenting to a Level 1 Trauma Center as a trauma activation. We observed less frequent VTE development in the marijuana-positive group compared to the marijuana-negative group, with patient thromboelastography revealing a longer mean R-time in the marijuana-positive group. Overall occurrence of VTE was too low for definitive conclusions, but a trend toward reduction in VTE frequency among marijuana users compared to nonusers was noted. More studies with larger populations and more VTE occurrences are needed to confirm a potential correlation between marijuana use and VTE development.
MeSH term(s)	Humans ; Venous Thromboembolism/epidemiology ; Venous Thromboembolism/etiology ; Retrospective Studies ; Marijuana Use ; Thrombelastography ; Substance-Related Disorders
Language	English
Publishing date	2023-02-23
Publishing country	United States
Document type	Journal Article
ZDB-ID	202465-2
ISSN	1555-9823 ; 0003-1348
ISSN (online)	1555-9823
ISSN	0003-1348
DOI	10.1177/00031348231157889
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Article ; Online: Frailty Is Associated With Worse Outcomes In Geriatric Pelvic Fractures.

Perea, Lindsey L / Fort, Launick Saint / Morgan, Madison E / Brown, Catherine Ting / Wang, Steadman / Bradburn, Eric

The American surgeon

2022 Volume 88, Issue 7, Page(s) 1573–1575

Abstract: Frail, geriatric patients with pelvic fractures can present differently than non-frail patients. Using the Clinical Frailty Scale(CFS), a retrospective analysis was conducted to determine the relationship between patients' CFS and outcomes after pelvic ... ...

Abstract	Frail, geriatric patients with pelvic fractures can present differently than non-frail patients. Using the Clinical Frailty Scale(CFS), a retrospective analysis was conducted to determine the relationship between patients' CFS and outcomes after pelvic fractures. We hypothesized that frail, geriatric trauma patients defined as a CFS>4 with pelvic fractures have worse outcomes than non-frail patients with a CFS≤4 despite similar injuries. All geriatric patients with pelvic fractures and documented CFS were included. Seventy patients were included, with 59% (n = 41) frail. The groups were compared with no difference in mortality. The frail group was older and were most likely discharged to a skilled nursing facility (65.8%). Non-frail were most likely discharged to acute rehab (52%). Frail had lower functional status at discharge (median: 14.5v.16, P = .015). Frail patients had worse overall outcomes in this analysis of geriatric pelvic fracture patients. Special attention should focus on this vulnerable population to ensure optimal treatment and outcomes.
MeSH term(s)	Aged ; Fractures, Bone/complications ; Frail Elderly ; Frailty/epidemiology ; Geriatric Assessment ; Humans ; Length of Stay ; Retrospective Studies
Language	English
Publishing date	2022-03-25
Publishing country	United States
Document type	Journal Article
ZDB-ID	202465-2
ISSN	1555-9823 ; 0003-1348
ISSN (online)	1555-9823
ISSN	0003-1348
DOI	10.1177/00031348221084943
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Article ; Online: Incidental Findings Protocol Implementation at a Level-I Trauma Center: A Review of Patient Follow-Up.

Martin, Sarah / LoPolito, Andrew / Whitney, Larissa D / Fenninger, Ashley / Bonneville, Kelly / Ward, Ryan / Graeff, Shelby / Saint Fort, Launick / Brown, Catherine T / Miller, Virginia / Perea, Lindsey L

The American surgeon

2023 Volume 89, Issue 7, Page(s) 3174–3179

Abstract: Objectives: Pan scanning in trauma patients has become routine, resulting in increased identification of incidental findings (IF), findings unrelated to the reason for the scan. This has posed a conundrum of ensuring patients have appropriate follow-up ... ...

Abstract	Objectives: Pan scanning in trauma patients has become routine, resulting in increased identification of incidental findings (IF), findings unrelated to the reason for the scan. This has posed a conundrum of ensuring patients have appropriate follow-up for these findings. We sought to evaluate our compliance and follow-up for patients after implementation of an IF protocol at our level-I trauma center. Methods: We performed a retrospective review from 9/2020 to 4/2021, to encompass before and after protocol implementation. Patients were separated into PRE and POST groups. Charts were reviewed evaluating several factors including three- and six-month follow-ups on IF. Data were analyzed comparing PRE and POST groups. Results: A total of 1989 patients were identified, 31.22% (n = 621) with an IF. 612 patients were included in our study. Compared to PRE, POST showed a significant increase in PCP notification (35% vs 22%, Conclusion: Implementation of an IF protocol with patient and PCP notification was significantly improved in overall patient follow-up for category one and two IF. Utilizing the results of this study, the protocol will be further revised to improve patient follow-up.
MeSH term(s)	Humans ; Trauma Centers ; Follow-Up Studies ; Incidental Findings ; Tomography, X-Ray Computed/methods ; Retrospective Studies ; Review Literature as Topic
Language	English
Publishing date	2023-02-15
Publishing country	United States
Document type	Journal Article
ZDB-ID	202465-2
ISSN	1555-9823 ; 0003-1348
ISSN (online)	1555-9823
ISSN	0003-1348
DOI	10.1177/00031348231157822
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Article ; Online: There's No Place Like Home: Delirium as a Barrier in Geriatric Trauma.

Toure, Abdoulaziz / Tadi, Roshan / Meagher, Mitchell / Brown, Catherine Ting / Lam, Hoi / LaRosa, Samantha / Saint-Fort, Launick / Syed, Huda / Harshaw, Nathaniel / Moore, Katherine / Sohail, Neelofer / Perea, Lindsey L

The Journal of surgical research

2023 Volume 293, Page(s) 89–94

Abstract: Introduction: Delirium is associated with a three-fold increase in frequency of 6-mo mortality following intensive care unit admission. Outside of mortality, it has been linked with severe morbidity including long-term cognitive decline, loss of ... ...

Abstract	Introduction: Delirium is associated with a three-fold increase in frequency of 6-mo mortality following intensive care unit admission. Outside of mortality, it has been linked with severe morbidity including long-term cognitive decline, loss of autonomy, and increased risk of institutionalization. There is a paucity of literature regarding delirium and geriatric trauma patients. The aim of our study is to determine predictive factors of delirium in geriatric trauma patients. Methods: This is a retrospective review of all geriatric (>65 y) trauma patients with a documented frailty score at a Level I Trauma Center from 1/2019 to 9/2021. Univariate and multivariate logistic regressions were performed. Geriatric patients with delirium (D) and those without delirium (ND) were compared. Patients were excluded if they did not have a documented frailty score or died before admission. Results: One thousand three hundred and seventeen patients met criteria; 40 (3%) patients developed delirium. Neither age nor gender was different between the two groups. Frailty scores were not different between the two groups. Patients with documented delirium had a higher incidence of a positive drug screen on admission (85% versus 62.2%, P = 0.0034), higher median injury severity score (10 versus 9, P = 0.0088), and longer hospital (7 d versus 3 d, P < 0.001) and intensive care unit (1 d versus 0 d, P < 0.001) length of stay (LOS) than their ND counterparts. The D group had a higher frequency of benzodiazepine (47.5% versus 19.3%, P < 0.001) and narcotic use (77.5% versus 56.5%, P = 0.0085). Tethers nor bedrest orders were significantly associated with delirium. Incidence of urinary tract infection (12.5% versus 1%, P < 0.001) and restraint use (P < 0.001) were significantly associated with increased risk of delirium. Additionally, those with a diagnosis of delirium were more often discharged to a skilled nursing facility than those in the ND group (45% versus 30.8%, P = 0.0006). Conclusions: We aimed to identify key predictive factors of delirium in our study population and found that certain factors correlated with higher frequencies of delirium in our geriatric trauma patients. Preadmission and early controlled substance use were significantly associated with delirium, as were the presence of urinary tract infection and extended intensive care unit LOS. By recognizing some of these modifiable factors, LOS may decrease while increasing the likelihood of discharge home.
MeSH term(s)	Humans ; Aged ; Frailty/complications ; Frailty/diagnosis ; Frailty/epidemiology ; Intensive Care Units ; Retrospective Studies ; Delirium/diagnosis ; Delirium/epidemiology ; Delirium/etiology ; Urinary Tract Infections ; Length of Stay
Language	English
Publishing date	2023-09-19
Publishing country	United States
Document type	Journal Article
ZDB-ID	80170-7
ISSN	1095-8673 ; 0022-4804
ISSN (online)	1095-8673
ISSN	0022-4804
DOI	10.1016/j.jss.2023.08.014
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Article: Surgical treatment of atrial fibrillation.

Saint, Lindsey L / Damiano, Ralph J

Missouri medicine

2012 Volume 109, Issue 4, Page(s) 281–287

Abstract: Atrial fibrillation (AF) is the most common cardiac arrhythmia, resulting in significant morbidity and mortality, and enormous socio-economic consequences. Though many surgical procedures exist for the treatment ofAF, the Cox-Maze IV procedure developed ... ...

Abstract	Atrial fibrillation (AF) is the most common cardiac arrhythmia, resulting in significant morbidity and mortality, and enormous socio-economic consequences. Though many surgical procedures exist for the treatment ofAF, the Cox-Maze IV procedure developed at Washington University has shown excellent long-term results in diverse patient populations. Furthermore, advances in preoperative diagnostic technology currently under investigation at our institution may allow for further refinement and individualization of the surgical treatment ofAF in the future.
MeSH term(s)	Atrial Fibrillation/classification ; Atrial Fibrillation/physiopathology ; Atrial Fibrillation/surgery ; Cardiac Surgical Procedures/methods ; Cardiopulmonary Bypass ; Catheter Ablation ; Electrophysiologic Techniques, Cardiac ; Humans ; Treatment Outcome
Language	English
Publishing date	2012-06-01
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	427362-x
ISSN	0026-6620
ISSN	0026-6620
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Article ; Online: Prevalence of hepatitis C virus among fatal drug overdoses in Tennessee: an analysis using 2019-2020 Tennessee State Unintentional Drug Overdose Reporting System Data.

Korona-Bailey, Jessica / Riley Saint, Sarah / Sizemore, Lindsey / Wingate, Heather / Shoup, Paula / Hawes, Amy / Mukhopadhyay, Sutapa

Annals of epidemiology

2023 Volume 80, Page(s) 1–8

Abstract: Purpose: Given the nature of the co-occurring epidemics of hepatitis C virus (HCV) and fatal stimulant overdose, we sought to assess the prevalence of HCV among opioid and stimulant-positive overdoses.: Methods: We conducted a cross-sectional study ... ...

Abstract	Purpose: Given the nature of the co-occurring epidemics of hepatitis C virus (HCV) and fatal stimulant overdose, we sought to assess the prevalence of HCV among opioid and stimulant-positive overdoses. Methods: We conducted a cross-sectional study to examine the prevalence of HCV among fatal drug overdoses in Tennessee using 2019-2020 data from the State Unintentional Drug Overdose Reporting System. We defined history of HCV using surveillance data and autopsy reports. Descriptive statistics were calculated for circumstances of overdose deaths for different categories of opioid and stimulant positivity on toxicology. Results: Between 2019 and 2020, 3570 unintentional or undetermined drug overdose deaths occurred in Tennessee with an available autopsy. History of HCV was found in 24.6% of deaths. When assessing different involvement between stimulants and opioids, the highest prevalence of HCV was found for deaths where methamphetamine and opioids were present in toxicology (35.4%). Scene evidence of injection drug use occurred more frequently among decedents with a history of HCV (P < .0001). Conclusions: This analysis while descriptive highlights the importance of linking datasets to enhance infectious disease and drug overdose surveillance. Partnership between communicable disease and drug overdose surveillance teams should continue to identify relationships between disease and drug overdose and strengthen the evidence to tailor crucial treatment and prevention activities.
MeSH term(s)	Humans ; Analgesics, Opioid/adverse effects ; Tennessee/epidemiology ; Hepacivirus ; Prevalence ; Cross-Sectional Studies ; Drug Overdose/epidemiology ; Hepatitis C/epidemiology
Chemical Substances	Analgesics, Opioid
Language	English
Publishing date	2023-02-08
Publishing country	United States
Document type	Journal Article ; Research Support, U.S. Gov't, P.H.S.
ZDB-ID	1074355-8
ISSN	1873-2585 ; 1047-2797
ISSN (online)	1873-2585
ISSN	1047-2797
DOI	10.1016/j.annepidem.2023.02.002
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Article: How I do it: minimally invasive Cox-Maze IV procedure.

Saint, Lindsey L / Lawrance, Christopher P / Leidenfrost, Jeremy E / Robertson, Jason O / Damiano, Ralph J

Annals of cardiothoracic surgery

2014 Volume 3, Issue 1, Page(s) 117–119

Language	English
Publishing date	2014-02-03
Publishing country	China
Document type	Journal Article ; Review
ZDB-ID	2713627-9
ISSN	2304-1021 ; 2225-319X
ISSN (online)	2304-1021
ISSN	2225-319X
DOI	10.3978/j.issn.2225-319X.2013.12.01
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Article: Illustrated techniques for performing the Cox-Maze IV procedure through a right mini-thoracotomy.

Robertson, Jason O / Saint, Lindsey L / Leidenfrost, Jeremy E / Damiano, Ralph J

Annals of cardiothoracic surgery

2014 Volume 3, Issue 1, Page(s) 105–116

Abstract: The Cox-Maze IV procedure has replaced the "cut-and-sew" technique of the original Cox-Maze operation with lines of ablation created using bipolar radiofrequency (RF) and cryothermal energy devices. In select patients, this procedure can be performed ... ...

Abstract	The Cox-Maze IV procedure has replaced the "cut-and-sew" technique of the original Cox-Maze operation with lines of ablation created using bipolar radiofrequency (RF) and cryothermal energy devices. In select patients, this procedure can be performed through a right mini-thoracotomy. This illustrated review is the first to detail the complete steps of the Cox-Maze IV procedure performed through a right mini-thoracotomy with careful attention paid to operative anatomy and advice. Pre- and post-operative management and outcomes are also discussed. This should be a practical guide for the practicing cardiac surgeon.
Language	English
Publishing date	2014-02-03
Publishing country	China
Document type	Journal Article ; Review
ZDB-ID	2713627-9
ISSN	2304-1021 ; 2225-319X
ISSN (online)	2304-1021
ISSN	2225-319X
DOI	10.3978/j.issn.2225-319X.2013.12.11
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