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Article: How blood met plastics, plant and animal extracts: Material encounters between medicine and industry in the twentieth century.

Prinz, Benjamin

Studies in history and philosophy of science

2022 Volume 92, Page(s) 45–55

Abstract: Twentieth-century medicine saw the remarkable rise of complex machines and infrastructures to process blood for medical purposes, such as transfusion, dialysis, and cardiac surgery. Instead of attributing these developments to technological ingenuity, ... ...

Abstract	Twentieth-century medicine saw the remarkable rise of complex machines and infrastructures to process blood for medical purposes, such as transfusion, dialysis, and cardiac surgery. Instead of attributing these developments to technological ingenuity, this article argues for the primacy of material encounters as a promising focal point of medical historiography. In fact, blood's special properties consistently clashed with most materials used in medical practice, provoking a series of material exchanges. Drawing on a combination of epistemological and network approaches, three exemplary cases are presented to examine blood's encounters with plastics, plant and animal extracts: William M. Bayliss's (1860-1926) injections of dissolved gum acacia to expand diminished blood volume; Charles H. Best's (1899-1978) production of the anticoagulant heparin from animal organs; and the preservation of fragile blood cells by silicone coatings inside of John H. Gibbon Jr.'s (1903-1973) heart-lung machine. The case studies demonstrate how the complementarity of blood and these materials produced hybridizations between medicine and a range of industrial branches, from colonial forestry and meatpacking to commercial chemistry. In this light, the paper concludes by discussing the dependencies of today's healthcare environments on globally distributed, capitalistically appropriated resources in the face of crises like the COVID-19 pandemic.
MeSH term(s)	Animals ; Blood ; Blood Chemical Analysis ; Blood Physiological Phenomena ; History, 20th Century ; Humans ; Medicine ; Plant Extracts ; Plastics/chemistry
Chemical Substances	Plant Extracts ; Plastics
Language	English
Publishing date	2022-02-04
Publishing country	England
Document type	Historical Article ; Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	202358-1
ISSN	1879-2510 ; 0039-3681
ISSN (online)	1879-2510
ISSN	0039-3681
DOI	10.1016/j.shpsa.2022.01.007
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Article ; Online: Operieren am blutleeren Herzen : Eine Geschichte chirurgischer Zeit zwischen Handwerk, Maschinen und Organismen, 1900–1950.

Prinz, Benjamin

NTM

2018 Volume 26, Issue 3, Page(s) 237–266

Abstract: Up until now time has rarely been considered in the historiography of surgery. However, the emergence of modern operating procedures is based significantly on establishing controlled relations of time by adjusting organic, technological and ... ...

Title translation	Operating upon the Bloodless Heart : A History of Surgical Time between Craft, Machines and Organisms, 1900-1950.
Abstract	Up until now time has rarely been considered in the historiography of surgery. However, the emergence of modern operating procedures is based significantly on establishing controlled relations of time by adjusting organic, technological and organizational processes. Early cardiac surgery in particular faced a crucial time problem: excluding the heart from the circulatory system long enough to operate inside its bloodless chambers. This problem can be traced back to the early 20th century, when surgeons such as Ludwig Rehn (1849-1930), Friedrich Trendelenburg (1844-1924), and Alexis Carrel (1873-1944) experimented with occlusions of the great vessels. Throughout the first half of the century, various attempts were made to prolong the possible time of circulatory arrest. In this regard, Arthur W. Meyer (1885-1934) in Berlin developed surgical craft procedures, John H. Gibbon Jr. (1903-1973) worked on constructing a heart-lung machine in Boston/Philadelphia, and Wilfred G. Bigelow in Toronto experimented with lowering the temperature of the body. Meticulous scrutiny of these developments illustrates how heterogeneous periods, rhythms, and paces had to be harmonized in order to gain decisive minutes or even seconds. Therefore, major developments on the way to open heart surgery can be described as a history of surgical time.
MeSH term(s)	Cardiac Surgical Procedures/history ; Heart Arrest, Induced/history ; Heart-Lung Machine/history ; History, 20th Century ; Humans ; Operative Time
Language	German
Publishing date	2018-06-30
Publishing country	Switzerland
Document type	Historical Article ; Journal Article
ZDB-ID	201410-5
ISSN	1420-9144 ; 0036-6978
ISSN (online)	1420-9144
ISSN	0036-6978
DOI	10.1007/s00048-018-0195-x
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Article ; Online: A Systematic Literature Review of Virtual Reality Locomotion Taxonomies.

Prinz, Lisa Marie / Mathew, Tintu / Weyers, Benjamin

IEEE transactions on visualization and computer graphics

2023 Volume 29, Issue 12, Page(s) 5208–5223

Abstract: The change of the user's viewpoint in an immersive virtual environment, called locomotion, is one of the key components in a virtual reality interface. Effects of locomotion, such as simulator sickness or disorientation, depend on the specific design of ... ...

Abstract	The change of the user's viewpoint in an immersive virtual environment, called locomotion, is one of the key components in a virtual reality interface. Effects of locomotion, such as simulator sickness or disorientation, depend on the specific design of the locomotion method and can influence the task performance as well as the overall acceptance of the virtual reality system. Thus, it is important that a locomotion method achieves the intended effects. The complexity of this task has increased with the growing number of locomotion methods and design choices in recent years. Locomotion taxonomies are classification schemes that group multiple locomotion methods and can aid in the design and selection of locomotion methods. Like locomotion methods themselves, there exist multiple locomotion taxonomies, each with a different focus and, consequently, a different possible outcome. However, there is little research that focuses on locomotion taxonomies. We performed a systematic literature review to provide an overview of possible locomotion taxonomies and analysis of possible decision criteria such as impact, common elements, and use cases for locomotion taxonomies. We aim to support future research on the design, choice, and evaluation of locomotion taxonomies and thereby support future research on virtual reality locomotion.
Language	English
Publishing date	2023-11-10
Publishing country	United States
Document type	Journal Article
ISSN	1941-0506
ISSN (online)	1941-0506
DOI	10.1109/TVCG.2022.3206915
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Article ; Online: Coherent response of the electronic system driven by non-interfering laser pulses.

Eul, Tobias / Prinz, Eva / Hartelt, Michael / Frisch, Benjamin / Aeschlimann, Martin / Stadtmüller, Benjamin

Nature communications

2022 Volume 13, Issue 1, Page(s) 3324

Abstract: The strength of light-matter interaction in condensed matter is fundamentally linked to the orientation and oscillation strength of the materials' optical transition dipoles. Structurally anisotropic materials, e.g., elongated molecules, exhibit optical ... ...

Abstract	The strength of light-matter interaction in condensed matter is fundamentally linked to the orientation and oscillation strength of the materials' optical transition dipoles. Structurally anisotropic materials, e.g., elongated molecules, exhibit optical transition dipoles with fixed orientations that govern the angular-dependent light-matter interaction. Contrary, free electron-like metals should exhibit isotropic light-matter interaction with the light fields dictating the orientation of the optical transition dipoles. Here, we demonstrate that an anisotropic direction of the optical transition dipoles even exists in highly free electron-like noble metal surfaces. Our time- and phase-resolved photoemission experiment reveals coherent interference effects on the (110)-oriented silver surface after optical excitation with two non-interfering cross-polarized pulses. We explain this coherent material response within the density matrix formalism by an intrinsic coupling of the non-interfering light fields mediated by optical transition dipoles with fixed orientations in silver.
Language	English
Publishing date	2022-06-09
Publishing country	England
Document type	Journal Article
ZDB-ID	2553671-0
ISSN	2041-1723 ; 2041-1723
ISSN (online)	2041-1723
ISSN	2041-1723
DOI	10.1038/s41467-022-30768-9
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Article ; Online: Coherent response of the electronic system driven by non-interfering laser pulses

Tobias Eul / Eva Prinz / Michael Hartelt / Benjamin Frisch / Martin Aeschlimann / Benjamin Stadtmüller

Nature Communications, Vol 13, Iss 1, Pp 1-

2022 Volume 8

Abstract: Light–matter interaction is expected to be isotropic in free-electron-like materials. Here, by using time- and phase-resolved photoemission, the authors observe signatures of an anisotropic interaction on a noble metal surface, that can only be accounted ...

Abstract	Light–matter interaction is expected to be isotropic in free-electron-like materials. Here, by using time- and phase-resolved photoemission, the authors observe signatures of an anisotropic interaction on a noble metal surface, that can only be accounted for by optical transition dipoles with a fixed orientation.
Keywords	Science ; Q
Language	English
Publishing date	2022-06-01T00:00:00Z
Publisher	Nature Portfolio
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Book ; Online: Twisted light affects ultrafast demagnetization

Prinz, Eva / Stadtmüller, Benjamin / Aeschlimann, Martin

2022

Abstract: Irradiation with an ultrashort laser pulse can completely destroy the magnetic order of ferromagnetic thin films on the femtosecond timescale. This phenomenon holds great potential for ultrafast spintronics and information processing and is an active ... ...

Abstract	Irradiation with an ultrashort laser pulse can completely destroy the magnetic order of ferromagnetic thin films on the femtosecond timescale. This phenomenon holds great potential for ultrafast spintronics and information processing and is an active field of research. It is still an open question if the angular momentum of light can support this effect. While it has been shown that the spin of light only has a negligible influence, we experimentally demonstrate the influence of ultrashort laser pulses with orbital angular momentum (OAM) on the magnetization dynamics of a thin nickel film. Our results reveal that the photonic OAM affects the demagnetization behavior within the first hundreds of femtoseconds depending on the handedness of the OAM with respect to the direction of the sample magnetization.
Keywords	Physics - Optics ; Condensed Matter - Materials Science
Publishing date	2022-06-15
Publishing country	us
Document type	Book ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Conference proceedings: The Yin and Yang of γδ T cells in hepatitis B virus (HBV) infection

Steppich, Katja / Souleiman, Roni / Bruni, Elena / Lara, Ximena Leon / Deterding, Katja / Maasoumy, Benjamin / Wedemeyer, Heiner / Prinz, Immo / Kraft, Anke / Cornberg, Markus

Zeitschrift für Gastroenterologie

2024 Volume 62, Issue 01

Event/congress	40. Jahrestagung der Deutschen Arbeitsgemeinschaft zum Studium der Leber, Haus der Technik e.V., Essen, 2024-01-26
Language	German
Publishing date	2024-01-01
Publisher	Georg Thieme Verlag
Publishing place	Stuttgart ; New York
Document type	Article ; Conference proceedings
ZDB-ID	201387-3
ISSN	1439-7803 ; 0044-2771 ; 0172-8504
ISSN (online)	1439-7803
ISSN	0044-2771 ; 0172-8504
DOI	10.1055/s-0043-1777644
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Zs.A 111/X: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)

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Article ; Online: Energy and Momentum Distribution of Surface Plasmon-Induced Hot Carriers Isolated

Hartelt, Michael / Terekhin, Pavel N / Eul, Tobias / Mahro, Anna-Katharina / Frisch, Benjamin / Prinz, Eva / Rethfeld, Baerbel / Stadtmüller, Benjamin / Aeschlimann, Martin

ACS nano

2021 Volume 15, Issue 12, Page(s) 19559–19569

Abstract: Understanding the differences between photon-induced and plasmon-induced hot electrons is essential for the construction of devices for plasmonic energy conversion. The mechanism of the plasmonic enhancement in photochemistry, photocatalysis, and light- ... ...

Abstract	Understanding the differences between photon-induced and plasmon-induced hot electrons is essential for the construction of devices for plasmonic energy conversion. The mechanism of the plasmonic enhancement in photochemistry, photocatalysis, and light-harvesting and especially the role of hot carriers is still heavily discussed. The question remains, if plasmon-induced and photon-induced hot carriers are fundamentally different or if plasmonic enhancement is only an effect of field concentration producing these carriers in greater numbers. For the bulk plasmon resonance, a fundamental difference is known, yet for the technologically important surface plasmons, this is far from being settled. The direct imaging of surface plasmon-induced hot carriers could provide essential insight, but the separation of the influence of driving laser, field-enhancement, and fundamental plasmon decay has proven to be difficult. Here, we present an approach using a two-color femtosecond pump-probe scheme in time-resolved 2-photon-photoemission (tr-2PPE), supported by a theoretical analysis of the light and plasmon energy flow. We separate the energy and momentum distribution of the plasmon-induced hot electrons from that of photoexcited electrons by following the spatial evolution of photoemitted electrons with energy-resolved photoemission electron microscopy (PEEM) and momentum microscopy during the propagation of a surface plasmon polariton (SPP) pulse along a gold surface. With this scheme, we realize a direct experimental access to plasmon-induced hot electrons. We find a plasmonic enhancement toward high excitation energies and small in-plane momenta, which suggests a fundamentally different mechanism of hot electron generation, as previously unknown for surface plasmons.
Language	English
Publishing date	2021-12-01
Publishing country	United States
Document type	Journal Article
ISSN	1936-086X
ISSN (online)	1936-086X
DOI	10.1021/acsnano.1c06586
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Article ; Online: Long-term effectiveness of a hyaluronic acid soft tissue filler in patients with facial lipoatrophy, morphological asymmetry, or debilitating scars.

Grablowitz, Doris / Ivezic-Schoenfeld, Zrinka / Federspiel, Ira G / Gehl, Benjamin / Kopera, Daisy / Prinz, Martin

Journal of cosmetic dermatology

2020 Volume 19, Issue 10, Page(s) 2536–2541

Abstract: Background: Soft tissue fillers are typically used for rejuvenating an aging face; they are also employed in the treatment of certain pathologic conditions, including facial lipoatrophy, morphological asymmetry, and debilitating scars.: Aims: The aim ...

Abstract	Background: Soft tissue fillers are typically used for rejuvenating an aging face; they are also employed in the treatment of certain pathologic conditions, including facial lipoatrophy, morphological asymmetry, and debilitating scars. Aims: The aim of this clinical study was to evaluate the effectiveness and safety of Princess® Volume (PV) in patients with facial lipoatrophy (FLA), morphological asymmetry (MA), or debilitating scars (DS). Patients/methods: This prospective, noncomparative, multicenter clinical study consisted of five visits spread across 36 weeks. Up to 60 adult patients suffering from moderate facial lipoatrophy, facial morphological asymmetry, or debilitating scars on the face were to be included. All patients were treated with an HA filler (PV). Results: At Week 4, the treatment success rate in the SP was 98% (95% CI [90.4%, 100%]), as assessed by both the investigators and the patients. According to the independent reviewer, the success rate was 93% (95% CI [82.7%, 98.0%]). At Week 24, the effect was maintained in most patients, with success rates of 80% as evaluated by the investigator and 79% by the patient (95% CI [67.6%, 89.8%] and [65.6%, 88.4%], respectively). At Week 36, success rates dropped to 61% as assessed by the investigator and 59% by the patient (95% CI [46.8%, 73.5%] and [45.0%, 71.9%], respectively). Conclusions: The clinical study has proven that Princess
MeSH term(s)	Adult ; Cicatrix/etiology ; Cosmetic Techniques ; Face ; Humans ; Hyaluronic Acid ; Prospective Studies
Chemical Substances	Hyaluronic Acid (9004-61-9)
Language	English
Publishing date	2020-06-22
Publishing country	England
Document type	Journal Article ; Multicenter Study
ZDB-ID	2280551-5
ISSN	1473-2165 ; 1473-2130
ISSN (online)	1473-2165
ISSN	1473-2130
DOI	10.1111/jocd.13454
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Article ; Online: Inflammasome signaling is dispensable for ß-amyloid-induced neuropathology in preclinical models of Alzheimer's disease.

Frontiers in immunology

2024 Volume 15, Page(s) 1323409

Abstract: Background: Alzheimer's disease (AD) is the most common neurodegenerative disorder affecting memory and cognition. The disease is accompanied by an abnormal deposition of ß-amyloid plaques in the brain that contributes to neurodegeneration and is known ... ...

Abstract	Background: Alzheimer's disease (AD) is the most common neurodegenerative disorder affecting memory and cognition. The disease is accompanied by an abnormal deposition of ß-amyloid plaques in the brain that contributes to neurodegeneration and is known to induce glial inflammation. Studies in the Methods: Here, we evaluated the Results: Microglia-specific deletion of the inflammasome regulator A20 and inflammasome effector protease caspase-1 in the Conclusion: Collectively, these results question a generalizable role for inflammasome activation in preclinical amyloid-only models of neuroinflammation.
MeSH term(s)	Mice ; Animals ; Alzheimer Disease/pathology ; Inflammasomes ; NLR Family, Pyrin Domain-Containing 3 Protein/genetics ; Amyloid beta-Peptides ; Amyloid beta-Protein Precursor/genetics ; Neuroinflammatory Diseases ; Mice, Transgenic ; Amyloid ; Amyloidogenic Proteins
Chemical Substances	Inflammasomes ; NLR Family, Pyrin Domain-Containing 3 Protein ; Amyloid beta-Peptides ; Amyloid beta-Protein Precursor ; Amyloid ; Amyloidogenic Proteins
Language	English
Publishing date	2024-01-29
Publishing country	Switzerland
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2606827-8
ISSN	1664-3224 ; 1664-3224
ISSN (online)	1664-3224
ISSN	1664-3224
DOI	10.3389/fimmu.2024.1323409
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