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  1. Article ; Online: Treatment of metastatic pancreatic cancer: 25 years of innovation with little progress for patients.

    Gyawali, Bishal / Booth, Christopher M

    The Lancet. Oncology

    2024  Volume 25, Issue 2, Page(s) 167–170

    MeSH term(s) Humans ; Pancreatic Neoplasms/therapy ; Pancreatic Neoplasms/pathology ; Adenocarcinoma/pathology ; Patients
    Language English
    Publishing date 2024-01-31
    Publishing country England
    Document type Journal Article
    ZDB-ID 2049730-1
    ISSN 1474-5488 ; 1470-2045
    ISSN (online) 1474-5488
    ISSN 1470-2045
    DOI 10.1016/S1470-2045(23)00516-8
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    Zs.A 5696: Show issues Location:
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    Zs.MO 460: Show issues

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  2. Article ; Online: Re-Examining Trials of Radiotherapy Omission: When Less Is Not Always More.

    Sanford, Nina N / Hall, William A / Booth, Christopher M

    JCO oncology practice

    2024  Volume 20, Issue 4, Page(s) 460–462

    MeSH term(s) Humans ; Radiation Oncology
    Language English
    Publishing date 2024-01-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 3028198-2
    ISSN 2688-1535 ; 2688-1527
    ISSN (online) 2688-1535
    ISSN 2688-1527
    DOI 10.1200/OP.23.00640
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 7198: Show issues Location:
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  3. Article ; Online: Common sense cancer care for older adults: Outcomes that matter.

    Frank, Christopher / Gyawali, Bishal / Booth, Christopher M

    Journal of the American Geriatrics Society

    2023  Volume 71, Issue 12, Page(s) 3977–3980

    MeSH term(s) Humans ; Aged ; Neoplasms/therapy ; Aging
    Language English
    Publishing date 2023-08-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80363-7
    ISSN 1532-5415 ; 0002-8614
    ISSN (online) 1532-5415
    ISSN 0002-8614
    DOI 10.1111/jgs.18529
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  4. Article ; Online: Reply to D.J. Stewart et al.

    Booth, Christopher M / Eisenhauer, Elizabeth A / Gyawali, Bishal / Tannock, Ian F

    Journal of clinical oncology : official journal of the American Society of Clinical Oncology

    2024  Volume 42, Issue 8, Page(s) 974–975

    Language English
    Publishing date 2024-01-30
    Publishing country United States
    Document type Journal Article
    ZDB-ID 604914-x
    ISSN 1527-7755 ; 0732-183X
    ISSN (online) 1527-7755
    ISSN 0732-183X
    DOI 10.1200/JCO.23.02595
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    Zs.MO 650: Show issues

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  5. Article ; Online: Contemporary clinical trials in hematologic cancer: Have we forgotten where we came from?

    Sengar, Manju / Booth, Christopher M

    European journal of cancer (Oxford, England : 1990)

    2022  Volume 167, Page(s) 161–163

    MeSH term(s) Hematologic Neoplasms/therapy ; Humans
    Language English
    Publishing date 2022-03-02
    Publishing country England
    Document type Editorial ; Comment
    ZDB-ID 82061-1
    ISSN 1879-0852 ; 0277-5379 ; 0959-8049 ; 0964-1947
    ISSN (online) 1879-0852
    ISSN 0277-5379 ; 0959-8049 ; 0964-1947
    DOI 10.1016/j.ejca.2022.01.024
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    Zs.A 456: Show issues Location:
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    Zs.MO 583: Show issues

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  6. Article ; Online: Cancer treatments should benefit patients: a common-sense revolution in oncology.

    Gyawali, Bishal / Booth, Christopher M

    Nature medicine

    2022  Volume 28, Issue 4, Page(s) 617–620

    MeSH term(s) Humans ; Medical Oncology ; Neoplasms/genetics ; Neoplasms/therapy
    Language English
    Publishing date 2022-02-25
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1220066-9
    ISSN 1546-170X ; 1078-8956
    ISSN (online) 1546-170X
    ISSN 1078-8956
    DOI 10.1038/s41591-021-01662-6
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    Zs.MG 39: Show issues

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  7. Article ; Online: How forced dichotomization hijacked meaningful debate during the COVID-19 pandemic.

    Booth, Christopher M / Detsky, Allan S

    Journal of hospital medicine

    2022  Volume 17, Issue 7, Page(s) 572–573

    MeSH term(s) COVID-19 ; Humans ; Pandemics
    Language English
    Publishing date 2022-05-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2233783-0
    ISSN 1553-5606 ; 1553-5592
    ISSN (online) 1553-5606
    ISSN 1553-5592
    DOI 10.1002/jhm.12841
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    Zs.A 6276: Show issues Location:
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    Zs.MO 542: Show issues

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  8. Article ; Online: Defining clinically important overall survival thresholds: lessons from quality of life.

    Gyawali, Bishal / Booth, Christopher M

    Nature reviews. Clinical oncology

    2022  Volume 19, Issue 10, Page(s) 613–614

    MeSH term(s) Humans ; Quality of Life ; Treatment Outcome
    Language English
    Publishing date 2022-07-27
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2491410-1
    ISSN 1759-4782 ; 1759-4774
    ISSN (online) 1759-4782
    ISSN 1759-4774
    DOI 10.1038/s41571-022-00667-5
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    Zs.A 6029: Show issues Location:
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    Zs.MG 103: Show issues

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  9. Article ; Online: Practicing on the edge of oncology: when standard of care feels uncomfortable.

    Booth, Christopher M / Goodman, Aaron M

    Nature reviews. Clinical oncology

    2021  Volume 18, Issue 11, Page(s) 673–674

    MeSH term(s) Humans ; Medical Oncology/methods ; Neoplasms/complications ; Standard of Care/standards
    Language English
    Publishing date 2021-08-12
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2491410-1
    ISSN 1759-4782 ; 1759-4774
    ISSN (online) 1759-4782
    ISSN 1759-4774
    DOI 10.1038/s41571-021-00550-9
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  10. Article: Exercise as cancer treatment: A clinical oncology framework for exercise oncology research.

    Courneya, Kerry S / Booth, Christopher M

    Frontiers in oncology

    2022  Volume 12, Page(s) 957135

    Abstract: Exercise has been proposed as a possible cancer treatment; however, there are an infinite number of clinical oncology settings involving diverse cancer types and treatment protocols in which exercise could be tested as a cancer treatment. The primary ... ...

    Abstract Exercise has been proposed as a possible cancer treatment; however, there are an infinite number of clinical oncology settings involving diverse cancer types and treatment protocols in which exercise could be tested as a cancer treatment. The primary purpose of this paper is to propose a conceptual framework to organize and guide research on exercise as a cancer treatment across distinct clinical oncology settings. A secondary purpose is to provide an overview of existing exercise research using the proposed framework. The Exercise as Cancer Treatment (EXACT) framework proposes nine distinct clinical oncology scenarios based on tumor/disease status and treatment status at the time of the proposed exercise treatment. In terms of tumor/disease status, the primary tumor has either been surgically removed (primary goal to treat micrometastases), not surgically removed (primary goal to treat the primary tumor), or metastatic disease is present (primary goal to treat metastatic disease). In terms of treatment status, the extant disease has either not been treated yet (treatment naïve), is currently being treated (active treatment), or has previously been treated. These two key clinical oncology variables-tumor/disease status and treatment status-result in nine distinct clinical oncology scenarios in which exercise could be tested as a new cancer treatment: (a) treatment naïve micrometastases, (b) actively treated micrometastases, (c) previously treated micrometastases, (d) treatment naïve primary tumors, (e) actively treated primary tumors, (f) previously treated primary tumors, (g) treatment naïve metastatic disease, (h) actively treated metastatic disease, and (i) previously treated metastatic disease. To date, most preclinical animal studies have examined the effects of exercise on treatment naïve and actively treated primary tumors. Conversely, most observational human studies have examined the associations between exercise and cancer recurrence/survival in patients actively treated or previously treated for micrometastases. Few clinical trials have been conducted in any of these scenarios. For exercise to be integrated into clinical oncology practice as a cancer treatment, it will need to demonstrate benefit in a specific clinical setting. The EXACT framework provides a simple taxonomy for systematically evaluating exercise as a potential cancer treatment across a diverse range of cancer types and treatment protocols.
    Language English
    Publishing date 2022-09-02
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2649216-7
    ISSN 2234-943X
    ISSN 2234-943X
    DOI 10.3389/fonc.2022.957135
    Database MEDical Literature Analysis and Retrieval System OnLINE

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