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  1. Article: Comparison among three different follow-up models for obstructive sleep apnea syndrome patients: focus on the physiotherapist's role.

    Simonelli, Carla / Vitacca, Michele / Salvi, Beatrice / Saleri, Manuela / Paneroni, Mara

    Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace

    2023  

    Abstract: In obstructive sleep apnea syndrome (OSAS) subjects different follow-up modalities have been proposed to improve adherence to the continuous positive airway pressure (CPAP) device. This retrospective study compares three different health professional ... ...

    Abstract In obstructive sleep apnea syndrome (OSAS) subjects different follow-up modalities have been proposed to improve adherence to the continuous positive airway pressure (CPAP) device. This retrospective study compares three different health professional approaches dedicated to caring OSAS patients in three consecutive follow-up periods of 15 months each. The three different follow-up models are: i) physician-oriented follow-up (P-F); ii) physiotherapist-oriented follow-up (PT-F); and iii) tele-titration plus PT-oriented follow-up (TT-PT-F). Health personal visits and actions delivered, patients' adherence, CPAP efficacy, and problems under CPAP use were considered for comparison. Data from 122 OSAS patients with a new prescription of CPAP were analyzed: 39 (32.0%) in the P-F, 38 (31.1%) in the PT-F, and 45 (36.9%) in the TT-PT-F period. We found a reduction over time (from 40.9% in P-F to 8.2% in TT-PT-F, p<0.001) in patients missing the 1-year follow-up visit. The PT-F and TT-PT-F lead to a reduction in physician visits in comparison to P-F (5.2% and 8.9% vs 100%, p<0.001) with no differences in time to the first follow-up visit, CPAP efficacy, and patients' adherence among the three periods. More device-related problems were found in the PT-F (57.8%), compared with the PF (25.6%) period (p<0.001); the most common troubles were mask problems evaluated in 26.2% of cases. In conclusion, different follow-up models offer similar efficacy and short-term adherence for CPAP leading to a significant reduction in physician visits under the PT-F with or without tele-titration, being mask problems as the most commonly treated. Further analysis should be useful to define the best cost-efficacy follow-up intervention.
    Language English
    Publishing date 2023-10-04
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 1160940-0
    ISSN 1122-0643 ; 1120-0391
    ISSN 1122-0643 ; 1120-0391
    DOI 10.4081/monaldi.2023.2673
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Comparison among three different follow-up models for obstructive sleep apnea syndrome patients

    Carla Simonelli / Michele Vitacca / Beatrice Salvi / Manuela Saleri / Mara Paneroni

    Monaldi Archives for Chest Disease (2023)

    focus on the physiotherapist’s role

    2023  

    Abstract: In obstructive sleep apnea syndrome (OSAS) subjects different follow-up modalities have been proposed to improve adherence to the continuous positive airway pressure (CPAP) device. This retrospective study compares three different health professional ... ...

    Abstract In obstructive sleep apnea syndrome (OSAS) subjects different follow-up modalities have been proposed to improve adherence to the continuous positive airway pressure (CPAP) device. This retrospective study compares three different health professional approaches dedicated to caring OSAS patients in three consecutive follow-up periods of 15 months each. The three different follow-up models are: i) physician-oriented follow-up (P-F); ii) physiotherapist-oriented follow-up (PT-F); and iii) tele-titration plus PT-oriented follow-up (TT-PT-F). Health personal visits and actions delivered, patients' adherence, CPAP efficacy, and problems under CPAP use were considered for comparison. Data from 122 OSAS patients with a new prescription of CPAP were analyzed: 39 (32.0%) in the P-F, 38 (31.1%) in the PT-F, and 45 (36.9%) in the TT-PT-F period. We found a reduction over time (from 40.9% in P-F to 8.2% in TT-PT-F, p<0.001) in patients missing the 1-year follow-up visit. The PT-F and TT-PT-F lead to a reduction in physician visits in comparison to P-F (5.2% and 8.9% vs 100%, p<0.001) with no differences in time to the first follow-up visit, CPAP efficacy, and patients’ adherence among the three periods. More device-related problems were found in the PT-F (57.8%), compared with the PF (25.6%) period (p<0.001); the most common troubles were mask problems evaluated in 26.2% of cases. In conclusion, different follow-up models offer similar efficacy and short-term adherence for CPAP leading to a significant reduction in physician visits under the PT-F with or without tele-titration, being mask problems as the most commonly treated. Further analysis should be useful to define the best cost-efficacy follow-up intervention.
    Keywords OSAS ; CPAP ; sleep apnea disorders ; rehabilitation ; Medicine ; R
    Language English
    Publishing date 2023-10-01T00:00:00Z
    Publisher PAGEPress Publications
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Measures of physical performance in COVID-19 patients: a mapping review.

    Simonelli, Carla / Paneroni, Mara / Vitacca, Michele / Ambrosino, Nicolino

    Pulmonology

    2021  Volume 27, Issue 6, Page(s) 518–528

    Abstract: Background and objective: There is evidence of short- and long-term impairment of physical performance in patients with COVID-19 infection, but a verification of measures of physical impairment in this condition is lacking. We reviewed the measures used ...

    Abstract Background and objective: There is evidence of short- and long-term impairment of physical performance in patients with COVID-19 infection, but a verification of measures of physical impairment in this condition is lacking. We reviewed the measures used to assess physical performance in these patients. Secondary targets were measures of exercise or daily life activities induced symptoms.
    Methods: Medline, CINAHL, and Pedro databases were searched from January 2020 to February 2021 for articles in the English language. Two investigators independently conducted the search, screened all titles and/or abstracts based on the inclusion criteria and independently scored the studies. The quality of the studies was evaluated by two reviewers according to the NIH quality assessment tool for observational cohort and cross-sectional studies. Discrepancies were resolved through consensus.
    Results: Out of 156 potentially relevant articles, 31 observational studies (8 cross-sectional), 1 randomized controlled trial, and 1 protocol were included. The quality of most of the 31 evaluable studies was judged as low (11 studies) or fair (14 studies). Sample sizes of the studies ranged from 14 to 20,889 patients. among the 28 reported measures, Barthel Index (42.4% of studies), Six-Minute Walking Distance Test (36.4%), Short Physical Performance Battery (21.2%) and 1-Minute Sit-to-Stand (12.1%) were the most used. Fifteen% and 36% of studies reported exercise induced desaturation and dyspnoea when performing the assessments, respectively. Other exercise induced symptoms were fatigue and pain. Studies reported wide ranges of impairment in physical performance as compared to "reference" values (range of mean or median reported values vs "reference values": 11-77 vs 100 points for Barthel Index; 11-22 vs 22-37 repetitions/min for 1m-STS; 0.5-7.9 vs 11.4 ± 1.3 points for SPPB; and 45-223 vs 380-782 m for 6MWT respectively).
    Conclusion: This review found that a wide variety of functional status tests have been used, making comparisons difficult between studies. These measures show impairment in physical performance in COVID-19 patients. However, the quality of most of the studies was judged as low or fair.
    MeSH term(s) Activities of Daily Living ; COVID-19/physiopathology ; Cross-Sectional Studies ; Exercise ; Humans ; Observational Studies as Topic ; Physical Functional Performance ; Randomized Controlled Trials as Topic
    Language English
    Publishing date 2021-06-24
    Publishing country Spain
    Document type Journal Article ; Review
    ZDB-ID 3009651-0
    ISSN 2531-0437 ; 2531-0429
    ISSN (online) 2531-0437
    ISSN 2531-0429
    DOI 10.1016/j.pulmoe.2021.06.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: The impact of the meta-analysis of pulmonary rehabilitation by Lacasse and colleagues: transforming pulmonary rehabilitation from "art to science".

    Gephine, Sarah / Simonelli, Carla / Vagheggini, Guido / Evans, Rachael / Ward, Thomas J C

    Breathe (Sheffield, England)

    2022  Volume 18, Issue 2, Page(s) 220021

    Abstract: Pulmonaryrehab was transformed in the 1990s into the standard of care for COPD: this article focuses on the impact of the 1996 meta-analysis by Lacasse and colleagues which provided the evidence to silence the ... ...

    Abstract #Pulmonaryrehab was transformed in the 1990s into the standard of care for COPD: this article focuses on the impact of the 1996 meta-analysis by Lacasse and colleagues which provided the evidence to silence the sceptics
    Language English
    Publishing date 2022-06-07
    Publishing country England
    Document type Journal Article
    ZDB-ID 2562899-9
    ISSN 2073-4735 ; 1810-6838
    ISSN (online) 2073-4735
    ISSN 1810-6838
    DOI 10.1183/20734735.0021-2022
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Predictors of Low Physical Function in Patients With COVID-19 With Acute Respiratory Failure Admitted to a Subacute Unit.

    Paneroni, Mara / Vogiatzis, Ioannis / Bertacchini, Laura / Simonelli, Carla / Vitacca, Michele

    Archives of physical medicine and rehabilitation

    2021  Volume 102, Issue 6, Page(s) 1228–1231

    Abstract: Objective: To document the level of physical function in patients with coronavirus disease 2019 (COVID-19) recovering from acute respiratory failure and investigate which patient clinical characteristics could predict physical function assessed by the ... ...

    Abstract Objective: To document the level of physical function in patients with coronavirus disease 2019 (COVID-19) recovering from acute respiratory failure and investigate which patient clinical characteristics could predict physical function assessed by the Short Physical Performance Battery (SPPB) test.
    Design: Cross-sectional study.
    Setting: Subacute unit of a Rehabilitation Institute.
    Participants: Patients with COVID-19 (N=184; aged 18 years or older) who were admitted to a subacute unit to stabilize their condition and recover from acute respiratory failure due to COVID-19.
    Interventions: Not applicable.
    Main outcome measures: At admission patients underwent the SPPB test, represented by the sum of 3 functional tests, standing balance, 4-meter gait speed, and 5-repetition sit-to-stand motion. Comparisons between 2 SPPB score groups were performed by an unpaired t test; multivariate stepwise linear regression analysis was employed to detect predictors of the SPPB score considering several clinical parameters.
    Results: Participants were 74±12 years old, 52% were men and with more than 2 comorbidities in 43% of cases. SPPB score was 3.02±3.87 denoting patients' profound physical dysfunction. Normal physical function was detected in only 12% of patients, whereas low, intermediate, and severe impairment was found in 65%, 13%, and 10%, respectively. Age, both invasive and noninvasive ventilation use, and the presence of previous disability were significant predictors of SPPB. Patients without any comorbidities (8%) also exhibited low function (SPPB: 5.67±1.12).
    Conclusions: The majority of survivors after COVID-19 experienced acute respiratory failure due to pneumonia and exhibited substantial physical dysfunction influenced by age, mechanical ventilation need, and previous disability. Further studies are needed to evaluate the role of rehabilitation to promote recovery and community reintegration in this population.
    MeSH term(s) Aged ; COVID-19/epidemiology ; COVID-19/rehabilitation ; Cross-Sectional Studies ; Disability Evaluation ; Disabled Persons/rehabilitation ; Female ; Follow-Up Studies ; Hospitalization/statistics & numerical data ; Humans ; Male ; Physical Functional Performance ; Retrospective Studies ; SARS-CoV-2 ; Walking Speed/physiology
    Language English
    Publishing date 2021-01-30
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 80057-0
    ISSN 1532-821X ; 0003-9993
    ISSN (online) 1532-821X
    ISSN 0003-9993
    DOI 10.1016/j.apmr.2020.12.021
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Correlation between Chest Computed Tomography Score and Laboratory Biomarkers in the Risk Stratification of COVID-19 Patients Admitted to the Emergency Department.

    D'Agostini, Cartesio / Legramante, Jacopo M / Minieri, Marilena / Di Lecce, Vito N / Lia, Maria Stella / Maurici, Massimo / Simonelli, Ilaria / Ciotti, Marco / Paganelli, Carla / Terrinoni, Alessandro / Giovannelli, Alfredo / Pieri, Massimo / Gallù, Mariacarla / Dell'Olio, Vito / Prezioso, Carla / Limongi, Dolores / Bernardini, Sergio / Orlacchio, Antonio

    Diagnostics (Basel, Switzerland)

    2023  Volume 13, Issue 17

    Abstract: Background: It has been reported that mid-regional proadrenomedullin (MR-proADM) could be considered a useful tool to stratify the mortality risk in COVID-19 patients upon admission to the emergency department (ED). During the COVID-19 outbreak, ... ...

    Abstract Background: It has been reported that mid-regional proadrenomedullin (MR-proADM) could be considered a useful tool to stratify the mortality risk in COVID-19 patients upon admission to the emergency department (ED). During the COVID-19 outbreak, computed tomography (CT) scans were widely used for their excellent sensitivity in diagnosing pneumonia associated with SARS-CoV-2 infection. However, the possible role of CT score in the risk stratification of COVID-19 patients upon admission to the ED is still unclear.
    Aim: The main objective of this study was to assess if the association of the CT findings alone or together with MR-proADM results could ameliorate the prediction of in-hospital mortality of COVID-19 patients at the triage. Moreover, the hypothesis that CT score and MR-proADM levels together could play a key role in predicting the correct clinical setting for these patients was also evaluated.
    Methods: Epidemiological, demographic, clinical, laboratory, and outcome data were assessed and analyzed from 265 consecutive patients admitted to the triage of the ED with a SARS-CoV-2 infection.
    Results and conclusions: The accuracy results by AUROC analysis and statistical analysis demonstrated that CT score is particularly effective, when utilized together with the MR-proADM level, in the risk stratification of COVID-19 patients admitted to the ED, thus helping the decision-making process of emergency physicians and optimizing the hospital resources.
    Language English
    Publishing date 2023-08-31
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662336-5
    ISSN 2075-4418
    ISSN 2075-4418
    DOI 10.3390/diagnostics13172829
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Aerobic Exercise Training in Very Severe Chronic Obstructive Pulmonary Disease: A Systematic Review and Meta-Analysis.

    Paneroni, Mara / Simonelli, Carla / Vitacca, Michele / Ambrosino, Nicolino

    American journal of physical medicine & rehabilitation

    2017  Volume 96, Issue 8, Page(s) 541–548

    Abstract: Objective: To evaluate the effectiveness of exercise training in patients with very severe chronic obstructive pulmonary disease (COPD).: Design: We searched MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials, and Cumulative Index to ... ...

    Abstract Objective: To evaluate the effectiveness of exercise training in patients with very severe chronic obstructive pulmonary disease (COPD).
    Design: We searched MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials, and Cumulative Index to Nursing and Allied Health Literature databases using the following as search terms: COPD, Chronic Obstructive Pulmonary Disease, Exercise, and Pulmonary Rehabilitation. We included randomized controlled trials (RCTs) of subjects with forced expiratory volume in the first second of less than 35% of the predicted normal value enrolled in in-patient, outpatient, or home- or community-based training programs lasting at least 4 weeks with respect to usual care. We included RCTs with outcome measures including the 6-minute walking test and/or health-related quality of life assessed by the St. George's Respiratory Questionnaire (SGRQ).
    Results: Of 580 articles screened, 10 were included. The programs' duration ranged from 4 to 52 weeks with 1 to 5 sessions per week lasting 15 to 40 minutes each. The intervention group improved in 6-minute walking test [weighted mean difference, 67.1 (95% confidence interval [CI], 37.897-98.927); standardized mean difference, 3.86 (95% CI, 2.04-5.67)], and St. George's Respiratory Questionnaire [weighted mean difference, -8.041 (95% CI, -15.273 to -0.809); standardized mean difference, -1.23 (95% CI, -2.14 to -0.31)].
    Conclusions: Exercise training improves exercise tolerance and health-related quality of life in patients with very severe COPD. However, because few studies on severely affected patients are available and the training programs are Highly heterogeneous, larger RCTs are needed.
    MeSH term(s) Aged ; Exercise ; Exercise Therapy/methods ; Exercise Tolerance ; Female ; Humans ; Male ; Middle Aged ; Physical Conditioning, Human ; Pulmonary Disease, Chronic Obstructive/physiopathology ; Pulmonary Disease, Chronic Obstructive/therapy ; Quality of Life ; Randomized Controlled Trials as Topic ; Severity of Illness Index ; Surveys and Questionnaires ; Treatment Outcome ; Walk Test
    Language English
    Publishing date 2017-08
    Publishing country United States
    Document type Journal Article ; Meta-Analysis ; Review
    ZDB-ID 219390-5
    ISSN 1537-7385 ; 0002-9491 ; 0894-9115
    ISSN (online) 1537-7385
    ISSN 0002-9491 ; 0894-9115
    DOI 10.1097/PHM.0000000000000667
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Physical Activity in Patients with Chronic Obstructive Pulmonary Disease on Long-Term Oxygen Therapy: A Cross-Sectional Study.

    Paneroni, Mara / Ambrosino, Nicolino / Simonelli, Carla / Bertacchini, Laura / Venturelli, Massimo / Vitacca, Michele

    International journal of chronic obstructive pulmonary disease

    2019  Volume 14, Page(s) 2815–2823

    Abstract: Background and aim: There are few studies evaluating physical activity (PA) in patients with chronic obstructive pulmonary disease (COPD) on long-term oxygen therapy (LTOT).: Aim: To assess PA in hypoxemic COPD patients on LTOT.: Methods: In this ... ...

    Abstract Background and aim: There are few studies evaluating physical activity (PA) in patients with chronic obstructive pulmonary disease (COPD) on long-term oxygen therapy (LTOT).
    Aim: To assess PA in hypoxemic COPD patients on LTOT.
    Methods: In this cross-sectional study, we compared lung function, arterial blood gases, respiratory and peripheral muscle strength, 6-min walking distance (6MWD), daily energy expenditure and steps, and health-related quality of life (HRQL) in COPD patients on LTOT (LTOT group) versus two groups of control patients not needing LTOT: with (HYPOX) and without (COPD) exercise-induced desaturations.
    Results: Groups did not differ as regards demographics, anthropometrics, peripheral or respiratory muscle strength. Compared to the other groups, LTOT patients had more severe airway obstruction and lung hyperinflation, greater number and severity of comorbidities, shorter 6MWD, as well as lower mean SpO
    Conclusion: COPD patients on LTOT perform less physical activity than patients not needing LTOT, both with and without exercise-induced desaturations. Patients with exercise-induced desaturations do not perform less physical activity than those without.
    MeSH term(s) Activities of Daily Living ; Adult ; Aged ; Aged, 80 and over ; Case-Control Studies ; Cost of Illness ; Cross-Sectional Studies ; Exercise ; Exercise Tolerance ; Female ; Humans ; Hypoxia/diagnosis ; Hypoxia/physiopathology ; Hypoxia/therapy ; Lung/physiopathology ; Male ; Middle Aged ; Muscle Strength ; Oxygen Inhalation Therapy/adverse effects ; Pulmonary Disease, Chronic Obstructive/diagnosis ; Pulmonary Disease, Chronic Obstructive/physiopathology ; Pulmonary Disease, Chronic Obstructive/therapy ; Quality of Life ; Time Factors ; Treatment Outcome
    Language English
    Publishing date 2019-12-05
    Publishing country New Zealand
    Document type Journal Article
    ISSN 1178-2005
    ISSN (online) 1178-2005
    DOI 10.2147/COPD.S228465
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: The impact of exercise training on fatigue in patients with chronic obstructive pulmonary disease: a systematic review and meta-analysis.

    Paneroni, Mara / Vitacca, Michele / Venturelli, Massimo / Simonelli, Carla / Bertacchini, Laura / Scalvini, Simonetta / Schena, Federico / Ambrosino, Nicolino

    Pulmonology

    2020  Volume 26, Issue 5, Page(s) 304–313

    Abstract: Introduction and objective: Fatigue can be divided in perceived fatigue, the feeling of exhaustion or lack of energy, and performance fatigue, the reduction in muscle force/activation during a given task. This meta-analysis evaluates the impact of ... ...

    Abstract Introduction and objective: Fatigue can be divided in perceived fatigue, the feeling of exhaustion or lack of energy, and performance fatigue, the reduction in muscle force/activation during a given task. This meta-analysis evaluates the impact of exercise training on fatigue, compared with normal care in patients with COPD.
    Material and methods: We searched randomised controlled trials on MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials and CINAHL databases from their inception to December, 31st 2019 using the terms COPD, Fatigue, Fatigability, Muscle activation, Muscle endurance, Muscle Performance, Voluntary Activation, Motoneuron excitability, Force Development, Exercise, AND Rehabilitation.
    Results: We evaluated 494 potential articles. Sixteen, all evaluating perceived fatigability, satisfied the inclusion criteria and were included. Twelve studies (463 patients) assessed fatigue by the Chronic Respiratory Questionnaire showing that intervention improved significantly more than the control group [SMD 0.708; 95% CI 0.510, 0.907; p < 0.001; I² = 34.3%; p = 0.116]. Two studies (68 patients) using the Fatigue Impact Scale, did not find any significant differences between groups [SMD -0.922; 95%CI -2.258, 0.413; p = 0.176; I² = 83.9%; p = 0.013]. Two studies (82 patients) assessed perceived fatigue by the Fatigue Severity Scale: the intervention improved significantly more than the control group [SMD -2.282; 95%CI -2.870, -1.699; p < 0.001; I² = 64.6%, p = 0.093]. No study evaluating performance fatigue was found.
    Conclusions: This study provided low-quality evidence of a positive impact of different exercise training programs on perceived fatigue in patients with COPD. Further studies are needed to assess the effects of exercise training on fatigue and to test tailored programs.
    MeSH term(s) Aged ; Case-Control Studies ; Data Management ; Exercise/physiology ; Exercise/psychology ; Exercise Tolerance/physiology ; Fatigue/psychology ; Fatigue/therapy ; Humans ; Middle Aged ; Muscle Strength ; Perception/physiology ; Pulmonary Disease, Chronic Obstructive/physiopathology ; Pulmonary Disease, Chronic Obstructive/rehabilitation ; Quality of Life/psychology ; Randomized Controlled Trials as Topic ; Severity of Illness Index ; Surveys and Questionnaires/statistics & numerical data
    Language English
    Publishing date 2020-03-14
    Publishing country Spain
    Document type Journal Article ; Meta-Analysis ; Systematic Review
    ZDB-ID 3009651-0
    ISSN 2531-0437 ; 2531-0429
    ISSN (online) 2531-0437
    ISSN 2531-0429
    DOI 10.1016/j.pulmoe.2020.02.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Muscle Strength and Physical Performance in Patients Without Previous Disabilities Recovering From COVID-19 Pneumonia.

    Paneroni, Mara / Simonelli, Carla / Saleri, Manuela / Bertacchini, Laura / Venturelli, Massimo / Troosters, Thierry / Ambrosino, Nicolino / Vitacca, Michele

    American journal of physical medicine & rehabilitation

    2020  Volume 100, Issue 2, Page(s) 105–109

    Abstract: Abstract: In this cross-sectional study, we evaluated skeletal muscle strength and physical performance (1-min sit-to-stand and short physical performance battery tests), dyspnea, fatigue, and single-breath counting at discharge from a postacute COVID ... ...

    Abstract Abstract: In this cross-sectional study, we evaluated skeletal muscle strength and physical performance (1-min sit-to-stand and short physical performance battery tests), dyspnea, fatigue, and single-breath counting at discharge from a postacute COVID department, in patients recovering from COVID-19 pneumonia who had no locomotor disability before the infection.Quadriceps and biceps were weak in 86% and 73% of the patients, respectively. Maximal voluntary contraction for quadriceps was 18.9 (6.8) kg and for biceps 15.0 (5.5) kg (i.e., 54% and 69% of the predicted normal value, respectively). The number of chair rises in the 1-min sit-to-stand test was 22.1 (7.3 corresponding to 63% of the predicted normal value), whereas the short physical performance battery score was 7.9 (3.3 corresponding to 74% of the predicted normal value). At the end of the 1-min sit-to-stand test, 24% of the patients showed exercise-induced desaturation. The single-breath counting count was 35.4 (12.3) corresponding to 72% that of healthy controls. Mild-to-moderate dyspnea and fatigue were found during activities of daily living (Borg scale score, median value = 0.5 [0-2] and 1 [0-2]) and after the 1-min sit-to-stand (Borg scale score, median value = 3 [2-5] and 1 [0-3]). Significant correlations were observed between muscle strength and physical performance indices (R = 0.31-0.69).The high prevalence of impairment in skeletal muscle strength and physical performance in hospitalized patients recovering from COVID-19 pneumonia without previous locomotor disabilities suggests the need for rehabilitation programs after discharge.
    MeSH term(s) Activities of Daily Living ; Adult ; Aged ; Aged, 80 and over ; COVID-19/physiopathology ; Cross-Sectional Studies ; Dyspnea/physiopathology ; Fatigue/physiopathology ; Female ; Humans ; Inpatients ; Male ; Middle Aged ; Muscle Strength/physiology ; Physical Functional Performance ; Pneumonia, Viral/physiopathology ; Pneumonia, Viral/virology ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-10-29
    Publishing country United States
    Document type Journal Article
    ZDB-ID 219390-5
    ISSN 1537-7385 ; 0002-9491 ; 0894-9115
    ISSN (online) 1537-7385
    ISSN 0002-9491 ; 0894-9115
    DOI 10.1097/PHM.0000000000001641
    Database MEDical Literature Analysis and Retrieval System OnLINE

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