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  1. Book: Stem cells

    Ratajczak, Mariusz Z.

    therapeutic applications

    (Advances in experimental medicine and biology ; 1201)

    2019  

    Author's details Mariusz Z. Ratajczak editor
    Series title Advances in experimental medicine and biology ; 1201
    Collection
    Language English
    Size xiv, 406 Seiten, Illustrationen
    Publisher Springer
    Publishing place Cham
    Publishing country Switzerland
    Document type Book
    HBZ-ID HT020335520
    ISBN 978-3-030-31205-3 ; 9783030312060 ; 3-030-31205-4 ; 3030312062
    Database Catalogue ZB MED Medicine, Health

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  2. Book: Adult stem cell therapies

    Ratajczak, Mariusz Z.

    alternatives to plasticity

    (Stem cell biology and regenerative medicine)

    2014  

    Author's details Mariusz Z. Ratajczak, ed
    Series title Stem cell biology and regenerative medicine
    Language German
    Size XV, 266 S. : Ill., graph. Darst.
    Publisher Humana Press
    Publishing place New York u.a.
    Publishing country Germany
    Document type Book
    HBZ-ID HT018438926
    ISBN 978-1-4939-1000-7 ; 9781493910014 ; 1-4939-1000-0 ; 1493910019
    DOI 10.1007/978-1-4939-1001-4
    Database Catalogue ZB MED Medicine, Health

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  3. Article ; Online: Leukemogenesis occurs in a microenvironment enriched by extracellular microvesicles/exosomes: recent discoveries and questions to be answered.

    Ratajczak, Mariusz Z / Ratajczak, Janina

    Leukemia

    2024  Volume 38, Issue 4, Page(s) 692–698

    Abstract: In single-cell organisms, extracellular microvesicles (ExMVs) were one of the first cell-cell communication platforms that emerged very early during evolution. Multicellular organisms subsequently adapted this mechanism. Evidence indicates that all types ...

    Abstract In single-cell organisms, extracellular microvesicles (ExMVs) were one of the first cell-cell communication platforms that emerged very early during evolution. Multicellular organisms subsequently adapted this mechanism. Evidence indicates that all types of cells secrete these small circular structures surrounded by a lipid membrane that may be encrusted by ligands and receptors interacting with target cells and harboring inside a cargo comprising RNA species, proteins, bioactive lipids, signaling nucleotides, and even entire organelles "hijacked" from the cells of origin. ExMVs are secreted by normal cells and at higher levels by malignant cells, and there are some differences in their cargo. On the one hand, ExMVs secreted from malignant cells interact with cells in the microenvironment, and in return, they are exposed by a "two-way mechanism" to ExMVs secreted by non-leukemic cells. Therefore, leukemogenesis occurs and progresses in ExMVs enriched microenvironments, and this biological fact has pathologic, diagnostic, and therapeutic implications. We are still trying to decipher this intriguing cell-cell communication language better. We will present a current point of view on this topic and review some selected most recent discoveries and papers.
    MeSH term(s) Humans ; Exosomes/metabolism ; Cell-Derived Microparticles ; Cell Communication ; Signal Transduction ; Proteins/metabolism ; Extracellular Vesicles/metabolism
    Chemical Substances Proteins
    Language English
    Publishing date 2024-02-22
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 807030-1
    ISSN 1476-5551 ; 0887-6924
    ISSN (online) 1476-5551
    ISSN 0887-6924
    DOI 10.1038/s41375-024-02188-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Stem Cell Reviews and Reports - New Developments.

    Ratajczak, Mariusz Z

    Stem cell reviews and reports

    2022  Volume 18, Issue 7, Page(s) 2207–2208

    Language English
    Publishing date 2022-08-31
    Publishing country United States
    Document type Editorial
    ZDB-ID 2495577-2
    ISSN 2629-3277 ; 1558-6804 ; 1550-8943
    ISSN (online) 2629-3277 ; 1558-6804
    ISSN 1550-8943
    DOI 10.1007/s12015-022-10450-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Cell Surface Membrane Lipid Rafts as Potent Regulators of Stem Cell Proliferation, Differentiation, Trafficking and Metabolism.

    Ratajczak, Mariusz Z

    Stem cell reviews and reports

    2022  Volume 19, Issue 1, Page(s) 1

    MeSH term(s) Cell Differentiation ; Signal Transduction ; Membrane Microdomains/metabolism ; Membrane Lipids/metabolism ; Cell Proliferation
    Chemical Substances Membrane Lipids
    Language English
    Publishing date 2022-12-14
    Publishing country United States
    Document type Editorial
    ZDB-ID 2495577-2
    ISSN 2629-3277 ; 1558-6804 ; 1550-8943
    ISSN (online) 2629-3277 ; 1558-6804
    ISSN 1550-8943
    DOI 10.1007/s12015-022-10484-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Stem Cell Reviews & Reports Enters 18

    Ratajczak, Mariusz Z

    Stem cell reviews and reports

    2021  Volume 18, Issue 1, Page(s) 1

    MeSH term(s) Publishing ; Stem Cells
    Language English
    Publishing date 2021-12-07
    Publishing country United States
    Document type Editorial
    ZDB-ID 2495577-2
    ISSN 2629-3277 ; 1558-6804 ; 1550-8943
    ISSN (online) 2629-3277 ; 1558-6804
    ISSN 1550-8943
    DOI 10.1007/s12015-021-10310-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: August Issue of Stem Cell Reviews and Reports Including a Spotlight Paper from Dr. Hal Broxmeyer on a Role of Brain in Regulating Hematopoiesis.

    Ratajczak, Mariusz Z

    Stem cell reviews and reports

    2021  Volume 17, Issue 4, Page(s) 1081–1082

    Language English
    Publishing date 2021-07-15
    Publishing country United States
    Document type Editorial
    ZDB-ID 2495577-2
    ISSN 2629-3277 ; 1558-6804 ; 1550-8943
    ISSN (online) 2629-3277 ; 1558-6804
    ISSN 1550-8943
    DOI 10.1007/s12015-021-10215-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: December Issue of Stem Cell Reviews and Reports Highlights Future Directions in the Mobilization of Hematopoietic Stem Cells and Presents Clinical Results of the First CAR-T Cell Treatment for Systemic Lupus Erythromatosus.

    Ratajczak, Mariusz Z

    Stem cell reviews and reports

    2021  Volume 17, Issue 6, Page(s) 1937–1938

    MeSH term(s) Hematopoietic Stem Cell Mobilization/methods ; Hematopoietic Stem Cells ; T-Lymphocytes
    Language English
    Publishing date 2021-11-02
    Publishing country United States
    Document type Editorial ; Introductory Journal Article
    ZDB-ID 2495577-2
    ISSN 2629-3277 ; 1558-6804 ; 1550-8943
    ISSN (online) 2629-3277 ; 1558-6804
    ISSN 1550-8943
    DOI 10.1007/s12015-021-10291-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Paper of the June Issue of Stem Cell Reviews and Reports Provides Further Evidence that Tissue Physiological Low Oxygen Tension in Contrast to Atmospheric Ambient Oxygen Tension Enhances Competence and Functional Properties of Stem Cells.

    Ratajczak, Mariusz Z

    Stem cell reviews and reports

    2021  Volume 17, Issue 3, Page(s) 701–702

    MeSH term(s) Cell Differentiation ; Oxygen/pharmacology ; Stem Cells
    Chemical Substances Oxygen (S88TT14065)
    Language English
    Publishing date 2021-04-23
    Publishing country United States
    Document type Editorial
    ZDB-ID 2495577-2
    ISSN 2629-3277 ; 1558-6804 ; 1550-8943
    ISSN (online) 2629-3277 ; 1558-6804
    ISSN 1550-8943
    DOI 10.1007/s12015-021-10171-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Stem Cell Reviews and Reports Enters 16th Year of Publishing.

    Ratajczak, Mariusz Z

    Stem cell reviews and reports

    2020  Volume 16, Issue 1, Page(s) 1–2

    MeSH term(s) Humans ; Publishing/trends ; Stem Cell Research ; Stem Cells
    Language English
    Publishing date 2020-01-06
    Publishing country United States
    Document type Editorial
    ZDB-ID 2495577-2
    ISSN 2629-3277 ; 1558-6804 ; 1550-8943
    ISSN (online) 2629-3277 ; 1558-6804
    ISSN 1550-8943
    DOI 10.1007/s12015-019-09951-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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