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  1. Article ; Online: The Role of the Mycobiome in Women’s Health

    Michelle Marie Esposito / Savannah Patsakos / Larisa Borruso

    Journal of Fungi, Vol 9, Iss 348, p

    2023  Volume 348

    Abstract: ... can provide insight into women’s health, diseases, and microbiome dysbiosis. Analyses of mycobiome composition ... help to elucidate the various roles of women’s mycobiome in homeostasis, microbiome interactions ...

    Abstract Although the human bacteriome and virome have gained a great deal of attention over the years, the human mycobiome has been far more neglected despite having significant value and implications in human health. In women, mycobiome profiles in breastmilk, vaginal regions, the gut, skin, and the oral cavity can provide insight into women’s health, diseases, and microbiome dysbiosis. Analyses of mycobiome composition under factors, such as health, age, diet, weight, and drug exposure (including antibiotic therapies), help to elucidate the various roles of women’s mycobiome in homeostasis, microbiome interactions (synergistic and antagonistic), and health. This review summarizes the most recent updates to mycobiome knowledge in these critical areas.
    Keywords mycobiome ; breastmilk ; candida ; dysbiosis ; synergistic ; Biology (General) ; QH301-705.5
    Language English
    Publishing date 2023-03-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article: Kinetics and Reaction Mechanism of Biothiols Involved in S

    Campodónico, Paola R / Alarcón-Espósito, Jazmín / Olivares, Belén

    Frontiers in chemistry

    2022  Volume 10, Page(s) 854918

    Abstract: Few kinetic parameters, or reaction rates, are known up to date in detail about 1-chloro and 1-fluoro-2,4-dinitrobenzene (ClDNB and FDNB, respectively) with a series of biothiols in aqueous media. These biological nucleophiles with thiol groups have been ...

    Abstract Few kinetic parameters, or reaction rates, are known up to date in detail about 1-chloro and 1-fluoro-2,4-dinitrobenzene (ClDNB and FDNB, respectively) with a series of biothiols in aqueous media. These biological nucleophiles with thiol groups have been widely used as a reference in nucleophile reactivity assays due to their prevalence and cellular abundance. The main aim of this study was to elucidate the reaction mechanism based on Brönsted-type plots and reactivity patterns of the electrophile/nucleophile pairs. A complete kinetic study was performed in terms of the comparison of Brönsted-type slope parameters (
    Language English
    Publishing date 2022-06-08
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2711776-5
    ISSN 2296-2646
    ISSN 2296-2646
    DOI 10.3389/fchem.2022.854918
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Post-Traumatic Osteoarthritis, Psychological Health, and Quality of Life After Lower Limb Injury in U.S. Service Members.

    Farrokhi, Shawn / Gunterstockman, Brittney Mazzone / Hendershot, Brad D / Russell Esposito, Elizabeth / McCabe, Cameron T / Watrous, Jessica R

    Military medicine

    2023  

    Abstract: Introduction: The aims of this project were to assess (1) the prevalence and timing of post-traumatic osteoarthritis (PTOA) after a traumatic lower limb injury, (2) the risk of PTOA based on injury type, and (3) the association of PTOA with ... ...

    Abstract Introduction: The aims of this project were to assess (1) the prevalence and timing of post-traumatic osteoarthritis (PTOA) after a traumatic lower limb injury, (2) the risk of PTOA based on injury type, and (3) the association of PTOA with psychological health and quality of life (QoL).
    Materials and methods: The Wounded Warrior Recovery Project (WWRP) database and the Expeditionary Medical Encounters Dataset were queried to identify service members injured during deployment. The Military Health System Data Repository was utilized to extract medical record data to identify individuals with PTOA. Data on PTSD, depression symptoms, and QoL were extracted from the WWRP.
    Results: Of the 2,061 WWRP participants with lower limb injuries, 124 (6%) were diagnosed with PTOA, with first PTOA diagnosis occurring 3.8 ± 3.1 years after injury. Of the injury categories identified, only fractures were associated with high odds of lower limb PTOA (adjusted odds ratio [OR] = 3.92, 95% confidence interval [CI]: 2.38, 6.44). Individuals with PTOA diagnoses reported lower QoL scores relative to those without PTOA (F(1,2057) = 14.21, B = -0.05, P < .05). Additionally, rates of PTSD and depression symptoms were high but not different between those with or without PTOA.
    Conclusions: Despite a low prevalence of lower limb PTOA in our study, fractures increased the risk of PTOA after deployment-related injuries. Additionally, those with PTOA reported lower QoL scores relative to those without PTOA. The findings of this study highlight the personalized needs of patients with trauma beyond just the repair of the immediate injury.
    Language English
    Publishing date 2023-12-18
    Publishing country England
    Document type Journal Article
    ZDB-ID 391061-1
    ISSN 1930-613X ; 0026-4075
    ISSN (online) 1930-613X
    ISSN 0026-4075
    DOI 10.1093/milmed/usad475
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Elemental sulfur-based autotrophic denitrification in stoichiometric S

    Huiliñir, C / Acosta, L / Yanez, D / Montalvo, S / Esposito, G / Retamales, G / Levicán, G / Guerrero, L

    Bioresource technology

    2020  Volume 307, Page(s) 123229

    Abstract: The inclusion of S ...

    Abstract The inclusion of S
    MeSH term(s) Autotrophic Processes ; Bioreactors ; Calibration ; Denitrification ; Nitrates ; Sulfur
    Chemical Substances Nitrates ; Sulfur (70FD1KFU70)
    Language English
    Publishing date 2020-03-20
    Publishing country England
    Document type Journal Article
    ZDB-ID 1065195-0
    ISSN 1873-2976 ; 0960-8524
    ISSN (online) 1873-2976
    ISSN 0960-8524
    DOI 10.1016/j.biortech.2020.123229
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Modelling the effect of SMP production and external carbon addition on S-driven autotrophic denitrification.

    Guerriero, Grazia / Mattei, Maria Rosaria / Papirio, Stefano / Esposito, Giovanni / Frunzo, Luigi

    Scientific reports

    2022  Volume 12, Issue 1, Page(s) 7008

    Abstract: The aim of this study was to develop a mathematical model to assess the effect of soluble microbial products production and external carbon source addition on the performance of a sulfur-driven autotrophic denitrification (SdAD) process. During SdAD, the ...

    Abstract The aim of this study was to develop a mathematical model to assess the effect of soluble microbial products production and external carbon source addition on the performance of a sulfur-driven autotrophic denitrification (SdAD) process. During SdAD, the growth of autotrophic biomass (AUT) was accompanied by the proliferation of heterotrophic biomass mainly consisting of heterotrophic denitrifiers (HD) and sulfate-reducing bacteria (SRB), which are able to grow on both the SMP derived from the microbial activities and on an external carbon source. The process was supposed to occur in a sequencing batch reactor to investigate the effects of the COD injection on both heterotrophic species and to enhance the production and consumption of SMP. The mathematical model was built on mass balance considerations and consists of a system of nonlinear impulsive differential equations, which have been solved numerically. Different simulation scenarios have been investigated by varying the main operational parameters: cycle duration, day of COD injection and quantity of COD injected. For cycle durations of more than 15 days and a COD injection after the half-cycle duration, SdAD represents the prevailing process and the SRB represent the main heterotrophic family. For shorter cycle duration and COD injections earlier than the middle of the cycle, the same performance can be achieved increasing the quantity of COD added, which results in an increased activity of HD. In all the performed simulation even in the case of COD addition, AUT remain the prevailing microbial family in the reactor.
    MeSH term(s) Autotrophic Processes ; Bioreactors ; Carbon ; Denitrification ; Heterotrophic Processes ; Sulfur
    Chemical Substances Sulfur (70FD1KFU70) ; Carbon (7440-44-0)
    Language English
    Publishing date 2022-04-29
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-022-10944-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Relative Effectiveness of BNT162b2, mRNA-1273, and Ad26.COV2.S Vaccines and Homologous Boosting in Preventing COVID-19 in Adults in the US.

    Hung Nguyen, Van / Boileau, Catherine / Bogdanov, Alina / Sredl, Meg / Bonafede, Mac / Ducruet, Thierry / Chavers, Scott / Rosen, Andrew / Martin, David / Buck, Philip / Esposito, Daina / Van de Velde, Nicolas / Mansi, James A

    Open forum infectious diseases

    2023  Volume 10, Issue 7, Page(s) ofad288

    Abstract: ... of a primary series of mRNA-1273 vs BNT162b2 and Ad26.COV2.S and a homologous mRNA booster against ... 95% CI, 14%-24%), while the rVE for mRNA-1273 vs Ad26.COV2.S was 50% (95% CI, 48%-51%), 50% (95% CI ... Conclusions: In this study, mRNA-1273 was more effective than BNT162b2 or Ad26.COV2.S following a primary ...

    Abstract Background: Few head-to-head comparisons have been performed on the real-world effectiveness of coronavirus disease 2019 (COVID-19) booster vaccines. We evaluated the relative effectiveness (rVE) of a primary series of mRNA-1273 vs BNT162b2 and Ad26.COV2.S and a homologous mRNA booster against any medically attended, outpatient, and hospitalized COVID-19.
    Methods: A data set linking primary care electronic medical records with medical claims data was used for this retrospective cohort study of US patients age ≥18 years vaccinated with a primary series between February and October 2021 (Part 1) and a homologous mRNA booster between October 2021 and January 2022 (Part 2). Adjusted hazard ratios (HRs) were derived from 1:1 matching adjusted across potential covariates. rVE was (1 - HR
    Results: Following adjustment, Part 1 rVE for mRNA-1273 vs BNT162b2 was 23% (95% CI, 22%-25%), 23% (95% CI, 22%-25%), and 19% (95% CI, 14%-24%), while the rVE for mRNA-1273 vs Ad26.COV2.S was 50% (95% CI, 48%-51%), 50% (95% CI, 48%-52%), and 57% (95% CI, 53%-61%) against any medically attended, outpatient, and hospitalized COVID-19, respectively. The adjusted rVE in Part 2 for mRNA-1273 vs BNT162b2 was 14% (95% CI, 10%-18%), 13% (95% CI, 8%-17%), and 19% (95% CI, 1%-34%) against any medically attended, outpatient, and hospitalized COVID-19, respectively. rVE against medically attended COVID-19 was higher in adults age ≥65 years (35%; 95% CI, 24%-47%) than in those age 18-64 years (13%; 95% CI, 9%-17%) after the booster.
    Conclusions: In this study, mRNA-1273 was more effective than BNT162b2 or Ad26.COV2.S following a primary series during the Delta-dominant period and more effective than BNT162b2 as a booster during the Omicron-dominant period.
    Language English
    Publishing date 2023-05-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2757767-3
    ISSN 2328-8957
    ISSN 2328-8957
    DOI 10.1093/ofid/ofad288
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Conference proceedings: What’s hidden under the gastric intestinal metaplasia? Diffuse-type adenocarcinoma discovered by targeted biopsies: a case-report

    Dilaghi, E. / Angeletti, S. / Pilozzi, E. / Annibale, B. / Lahner, E. / Esposito, G.

    Endoscopy

    2023  Volume 55, Issue S 02

    Event/congress ESGE Days 2023, Dublin, Ireland, 2023-04-20
    Language English
    Publishing date 2023-04-01
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article ; Conference proceedings
    ZDB-ID 80120-3
    ISSN 1438-8812 ; 0013-726X
    ISSN (online) 1438-8812
    ISSN 0013-726X
    DOI 10.1055/s-0043-1765793
    Database Thieme publisher's database

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  8. Article ; Online: The nature and structure of maternal parenting practices and infant behaviors in U.S. national and international samples.

    Bornstein, Marc H / Putnick, Diane L / Esposito, Gianluca / Pearson, Rebecca M

    Frontiers in child and adolescent psychiatry

    2023  Volume 2

    Abstract: ... in a U.S. national sample (: Background and rationale: A previous test of three competing models ...

    Abstract Methods: Twenty maternal parenting practices and 15 behaviors of their 5½- month-old infants in a U.S. national sample (
    Background and rationale: A previous test of three competing models of the nature and structure of the maternal parenting practices supported a hybrid 2 factor/6 domain model as superior to a 1-factor dimensional model and a multi-factor style model: Maternal parenting practices are structured into nurture, physical, social, didactic, material, and language domains undergirded by dyadic and extradyadic factors. Infant behaviors were organized into physical, social, exploration, nondistress vocalization, and distress communication domains. The current study sought to examine links connecting these previously identified maternal domains and factors with infant behavior domains using structural equation models.
    Results: Mothers' dyadic factor is associated with infant social behaviors with mother; and mothers' extradyadic factor and encouragement of infant physical development are associated with infant exploration of their immediate physical environment and physical development. Infant distress communication (and less nondistress vocalization) is associated with more maternal nurturing.
    Discussion: Mothers' parenting practices in the middle of the first year of infant life are commonly structured and adapted to specific needs and developmental tasks of infants. Evaluations of mother-infant interactions with national and international samples permit a wide yet judicious analysis of common vs. specific models of mother-infant relationships.
    Language English
    Publishing date 2023-05-26
    Publishing country Switzerland
    Document type Journal Article
    ISSN 2813-4540
    ISSN (online) 2813-4540
    DOI 10.3389/frcha.2023.1124037
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Urban Commons between Ostrom’s and Neo-Materialist Approaches

    Maria Patrizia Vittoria / Stefania Ragozino / Gabriella Esposito De Vita

    Land, Vol 12, Iss 524, p

    The Case of Lido Pola in Naples, Southern Italy

    2023  Volume 524

    Abstract: ... design context through two interpretative keys: Ostrom’s idea of sustainability and the recent hybrid neo ...

    Abstract The main aim of the study was reflecting on performative implications of the urban commons and their relational ability (i.e., inter- and/or intra-actioning) within an inclusive governance model and policy design context through two interpretative keys: Ostrom’s idea of sustainability and the recent hybrid neo-materialist urban and organizational theoretical path grounded within the Metzger–Barad–Latour analyses. Firstly, we focused on defining the theoretical setting, background and selected codes. The resulting scheme was tested with a mixed methodology within the case study of the Lido Pola Commons in Naples, Southern Italy. Empirical analysis benefits from long-lasting research experience on the area and an action-research processes aimed at codesigning a living civic lab. The discussion illustrates the main pivots of the internal/external validation of the case study results, thus contributing to enhancing a participatory policy design by raising awareness regarding social intra/interactions.
    Keywords urban commons ; intra-actioning ; governance model ; policy design ; Ostrom’s CPRs ; neo-materialist approaches ; Agriculture ; S
    Language English
    Publishing date 2023-02-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: Cardiac Imaging in Athlete’s Heart

    Marco Fogante / Giacomo Agliata / Maria Chiara Basile / Paolo Compagnucci / Giovanni Volpato / Umberto Falanga / Giulia Stronati / Federico Guerra / Davide Vignale / Antonio Esposito / Antonio Dello Russo / Michela Casella / Andrea Giovagnoni

    Medicina, Vol 57, Iss 455, p

    The Role of the Radiologist

    2021  Volume 455

    Abstract: Athlete’s heart (AH) is the result of morphological and functional cardiac modifications due ...

    Abstract Athlete’s heart (AH) is the result of morphological and functional cardiac modifications due to long-lasting athletic training. Athletes can develop very marked structural myocardial changes, which may simulate or cover unknown cardiomyopathies. The differential diagnosis between AH and cardiomyopathy is necessary to prevent the risk of catastrophic events, such as sudden cardiac death, but it can be a challenging task. The improvement of the imaging modalities and the introduction of the new technologies in cardiac magnetic resonance (CMR) and cardiac computed tomography (CCT) can allow overcoming this challenge. Therefore, the radiologist, specialized in cardiac imaging, could have a pivotal role in the differential diagnosis between structural adaptative changes observed in the AH and pathological anomalies of cardiomyopathies. In this review, we summarize the main CMR and CCT techniques to evaluate the cardiac morphology, function, and tissue characterization, and we analyze the imaging features of the AH and the key differences with the main cardiomyopathies.
    Keywords athlete’s heart ; cardiac magnetic resonance ; cardiac computed tomography ; cardiomyopathy ; sudden cardiac death ; Medicine (General) ; R5-920
    Subject code 610
    Language English
    Publishing date 2021-05-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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