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Article ; Online: Light People: Professor Xi-Cheng Zhang.

Wang, Hui

2022 Volume 11, Issue 1, Page(s) 272

Abstract: ... in terahertz research for many years, Professor Xi-Cheng Zhang works at the University of Rochester, one ...

Abstract	Editorial: As 5 G ever becomes a part of everyday life and 6 G is also on the agenda, terahertz technology has gradually become known by the public, and is referred to as the "third eye" for human beings to understand the world.Terahertz is considered one of the top ten technologies that will change the world due to its unique properties. In 2019, astronomers were able to observe a black hole for the first time, using a terahertz astronomical telescope. Terahertz is no longer far away from our lives, whether it is information, medicine, or food safety and other fields. It is everywhere, triggering major changes in people's work and lifestyle.Today's guest of Light People is an internationally renowned scholar who has been engaged in terahertz research for many years, Professor Xi-Cheng Zhang works at the University of Rochester, one of the three major optics educational centers in the United States. As a pioneer in the field of terahertz technology, after years of practice, he has successfully generated terahertz waves using water, changing how we see water with THz wave forever.Next, please follow the Light Science Editor into the terahertz world to learn about the latest and most cutting-edge science and technology and the "story" behind it.
Language	English
Publishing date	2022-09-14
Publishing country	England
Document type	Journal Article
ZDB-ID	2662628-7
ISSN	2047-7538 ; 2047-7538
ISSN (online)	2047-7538
ISSN	2047-7538
DOI	10.1038/s41377-022-00955-w
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Article ; Online: Genetic insights into the dissolution of dioecy in diploid persimmon Diospyros oleifera Cheng.

Sun, Peng / Nishiyama, Soichiro / Li, Huawei / Mai, Yini / Han, Weijuan / Suo, Yujing / Liang, Chengzhi / Du, Huilong / Diao, Songfeng / Wang, Yiru / Yuan, Jiaying / Zhang, Yue / Tao, Ryutaro / Li, Fangdong / Fu, Jianmin

BMC plant biology

2023 Volume 23, Issue 1, Page(s) 606

Abstract: Background: Dioecy, a sexual system of single-sexual (gynoecious/androecious) individuals, is rare in flowering plants. This rarity may be a result of the frequent transition from dioecy into systems with co-sexual individuals.: Results: In this ... ...

Abstract	Background: Dioecy, a sexual system of single-sexual (gynoecious/androecious) individuals, is rare in flowering plants. This rarity may be a result of the frequent transition from dioecy into systems with co-sexual individuals. Results: In this study, co-sexual expression (monoecy and hermaphroditic development), previously thought to be polyploid-specific in Diospyros species, was identified in the diploid D. oleifeara historically. We characterized potential genetic mechanisms that underlie the dissolution of dioecy to monoecy and andro(gyno)monoecy, based on multiscale genome-wide investigations of 150 accessions of Diospyros oleifera. We found all co-sexual plants, including monoecious and andro(gyno)monoecious individuals, possessed the male determinant gene OGI, implying the presence of genetic factors controlling gynoecia development in genetically male D. oleifera. Importantly, discrepancies in the OGI/MeGI module were found in diploid monoecious D. oleifera compared with polyploid monoecious D. kaki, including no Kali insertion on the promoter of OGI, no different abundance of smRNAs targeting MeGI (a counterpart of OGI), and no different expression of MeGI between female and male floral buds. On the contrary, in both single- and co-sexual plants, female function was expressed in the presence of a genome-wide decrease in methylation levels, along with sexually distinct regulatory networks of smRNAs and their targets. Furthermore, a genome-wide association study (GWAS) identified a genomic region and a DUF247 gene cluster strongly associated with the monoecious phenotype and several regions that may contribute to andromonoecy. Conclusions: Collectively, our findings demonstrate stable breakdown of the dioecious system in D. oleifera, presumably also a result of genomic features of the Y-linked region.
MeSH term(s)	Diospyros/genetics ; Diploidy ; Genome-Wide Association Study ; Genomics ; Polyploidy
Language	English
Publishing date	2023-11-30
Publishing country	England
Document type	Journal Article
ZDB-ID	2059868-3
ISSN	1471-2229 ; 1471-2229
ISSN (online)	1471-2229
ISSN	1471-2229
DOI	10.1186/s12870-023-04610-3
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Article ; Online: Reply to Cheng and Chuang.

Avery, Lindsay M / Kuti, Joseph L / Weisser, Maja / Egli, Adrian / Rybak, Michael J / Zasowski, Evan J / Arias, Cesar A / Contreras, German A / Chong, Pearlie P / Aitken, Samuel L / DiPippo, Adam J / Wang, Jann-Tay / Britt, Nicholas S / Nicolau, David P

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

2019 Volume 69, Issue 5, Page(s) 903–904

MeSH term(s)	Bacteremia ; Bacterial Infections ; Daptomycin ; Humans
Chemical Substances	Daptomycin (NWQ5N31VKK)
Language	English
Publishing date	2019-02-04
Publishing country	United States
Document type	Letter ; Comment
ZDB-ID	1099781-7
ISSN	1537-6591 ; 1058-4838
ISSN (online)	1537-6591
ISSN	1058-4838
DOI	10.1093/cid/ciz081
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Article ; Online: Cheng et al. reply.

Cheng, Heping / Wang, Wang / Wang, Xianhua / Sheu, Shey-Shing / Dirksen, Robert T / Dong, Meng-Qiu

Nature

2014 Volume 514, Issue 7523, Page(s) E14–5

MeSH term(s)	Animals ; Caenorhabditis elegans/metabolism ; Longevity ; Male ; Mitochondria/metabolism ; Superoxides/metabolism
Chemical Substances	Superoxides (11062-77-4)
Language	English
Publishing date	2014-10-22
Publishing country	England
Document type	Letter ; Comment
ZDB-ID	120714-3
ISSN	1476-4687 ; 0028-0836
ISSN (online)	1476-4687
ISSN	0028-0836
DOI	10.1038/nature13859
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Article ; Online: Correction: Cheng et al. Glutathione S-Transferases S1, Z1 and A1 Serve as Prognostic Factors in Glioblastoma and Promote Drug Resistance through Antioxidant Pathways.

Cheng, Bo / Wang, Yu / Ayanlaja, Abiola Abdulrahman / Zhu, Jing / Kambey, Piniel Alphayo / Qiu, Ziqiang / Zhang, Caiyi / Hu, Wei

Cells

2023 Volume 12, Issue 14

Abstract: The authors wish to make the following change to their paper [ ... ]. ...

Abstract	The authors wish to make the following change to their paper [...].
Language	English
Publishing date	2023-07-21
Publishing country	Switzerland
Document type	Published Erratum
ZDB-ID	2661518-6
ISSN	2073-4409 ; 2073-4409
ISSN (online)	2073-4409
ISSN	2073-4409
DOI	10.3390/cells12141908
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Article: Xiao Cheng Qi Decoction, an Ancient Chinese Herbal Mixture, Relieves Loperamide-Induced Slow-Transit Constipation in Mice: An Action Mediated by Gut Microbiota.

Tuohongerbieke, Amanguli / Wang, Huaiyou / Wu, Jiahui / Wang, Zhengqi / Dong, Tingxia / Huang, Yamiao / Zhu, Dequan / Sun, Dongmei / Tsim, Karl Wah Keung

Pharmaceuticals (Basel, Switzerland)

2024 Volume 17, Issue 2

Abstract: Xiao Cheng Qi (XCQ) decoction, an ancient Chinese herbal mixture, has been used in treating slow ...

Abstract	Xiao Cheng Qi (XCQ) decoction, an ancient Chinese herbal mixture, has been used in treating slow-transit constipation (STC) for years. The underlying action mechanism in relieving the clinical symptoms is unclear. Several lines of evidence point to a strong link between constipation and gut microbiota. Short-chain fatty acids (SCFAs) and microbial metabolites have been shown to affect 5-HT synthesis by activating the GPR43 receptor localized on intestinal enterochromaffin cells, since 5-HT receptors are known to influence colonic peristalsis. The objective of this study was to evaluate the efficacy of XCQ in alleviating clinical symptoms in a mouse model of STC induced by loperamide. The application of loperamide leads to a decrease in intestinal transport and fecal water, which is used to establish the animal model of STC. In addition, the relationship between constipation and gut microbiota was determined. The herbal materials, composed of Rhei Radix et Rhizoma (Rhizomes of
Language	English
Publishing date	2024-01-24
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2193542-7
ISSN	1424-8247
ISSN	1424-8247
DOI	10.3390/ph17020153
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Article ; Online: Flagellar sensilla of the hangingflies Bittacus planus Cheng and Bittacus sinicus Issiki (Mecoptera: Bittacidae).

Wang, Xiao-Yan / Hua, Bao-Zhen

Arthropod structure & development

2023 Volume 76, Page(s) 101297

Abstract: ... Cheng, 1949 and Bittacus sinicus Issiki, 1931 using scanning electron microscopy. Four types of sensilla ...

Abstract	Adult hangingflies are very sensitive to humidity, thereby frequently being used as ecological indicators to assess the degradation of the environment, especially forest ecosystems. Studies on the sense organs associated with hygro- and thermo-sensitivity, however, have been scant. Here, the ultramorphology and distribution of the flagellar sensilla were investigated in the adult hangingflies Bittacus planus Cheng, 1949 and Bittacus sinicus Issiki, 1931 using scanning electron microscopy. Four types of sensilla are identified in B. planus, including sensilla campaniformia, sensilla chaetica (SC1, SC2), sensilla basiconica (SB1, SB2), and sensilla coeloconica. In B. sinicus, sensilla chaetica III are present additionally from 7th to 14th flagellomeres. Abundant sensilla coeloconica are present on the flagella of Bittacus. Sensilla basiconica I are situated at the joints of flagellomeres. Sensilla campaniformia are densely distributed on the basal half of the first flagellomere, but scarcely on other flagellomeres. Sensilla chaetica II are present on the distal three flagellomeres. The size, abundance, and distribution of flagellar sensilla differ considerably between B. planus and B. sinicus. We infer that the abundance of sensilla coeloconica is likely associated with the hygro- and thermo-sensitivity in Bittacidae. Studies of flagellar sensilla can provide valuable information for subsequent electrophysiological, behavioral, biogeographical, and phylogenetic analyses of Bittacidae.
MeSH term(s)	Animals ; Ecosystem ; Phylogeny ; Sensilla ; Holometabola ; Flagella
Language	English
Publishing date	2023-08-20
Publishing country	England
Document type	Journal Article
ZDB-ID	2001498-3
ISSN	1873-5495 ; 1467-8039
ISSN (online)	1873-5495
ISSN	1467-8039
DOI	10.1016/j.asd.2023.101297
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Book ; Online: Peng Cheng Object Detection Benchmark for Smart City

Wang, Yaowei / Yang, Zhouxin / Liu, Rui / Li, Deng / Lai, Yuandu / Fang, Leyuan / Han, Yahong

2022

Abstract: Object detection is an algorithm that recognizes and locates the objects in the image and has a wide range of applications in the visual understanding of complex urban scenes. Existing object detection benchmarks mainly focus on a single specific ... ...

Abstract	Object detection is an algorithm that recognizes and locates the objects in the image and has a wide range of applications in the visual understanding of complex urban scenes. Existing object detection benchmarks mainly focus on a single specific scenario and their annotation attributes are not rich enough, these make the object detection model is not generalized for the smart city scenes. Considering the diversity and complexity of scenes in intelligent city governance, we build a large-scale object detection benchmark for the smart city. Our benchmark contains about 500K images and includes three scenarios: intelligent transportation, intelligent security, and drones. For the complexity of the real scene in the smart city, the diversity of weather, occlusion, and other complex environment diversity attributes of the images in the three scenes are annotated. The characteristics of the benchmark are analyzed and extensive experiments of the current state-of-the-art target detection algorithm are conducted based on our benchmark to show their performance.
Keywords	Computer Science - Computer Vision and Pattern Recognition
Subject code	006
Publishing date	2022-03-11
Publishing country	us
Document type	Book ; Online
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Article ; Online: Protective effects of Da-cheng-qi decoction in rats with intracerebral hemorrhage.

Zeng, Peng / Wang, Xiao-Ming / Su, Hong-Fei / Zhang, Teng / Ning, Lin-Na / Shi, Yan / Yang, Shu-Sheng / Lin, Li / Tian, Qing

Phytomedicine : international journal of phytotherapy and phytopharmacology

2021 Volume 90, Page(s) 153630

Abstract: ... modifying treatment. Da-cheng-qi decoction (DCQ), composed of rhubarb, is one of the most commonly used ...

Abstract	Background: Intracerebral hemorrhage (ICH), the most fatal subtype of stroke, has no disease-modifying treatment. Da-cheng-qi decoction (DCQ), composed of rhubarb, is one of the most commonly used Chinese traditional decoctions in ICH treatment. But the mechanism is not clear. Emodin is an active compound found in rhubarb. Purpose: To study the protective effects of DCQ on ICH and its possible mechanisms of action. Methods: The ICH model was reproduced by injecting collagenase-VII into the left caudate putamen (CPu) of rats. DCQ and emodin were used to treat the ICH rats for 7 days. Behavior tests, proteomic analysis, morphological studies, and western blotting were performed. Results: The neurological deficits in the ICH rats recovered with DCQ and emodin on the 14 Conclusion: The protective effects of DCQ on ICH were confirmed in this study, and its mechanism may be related to the inhibition of MAPK and activation of M2 microglia. These results are beneficial to the development of ICH therapeutic targets.
MeSH term(s)	Animals ; Cerebral Hemorrhage/drug therapy ; Drugs, Chinese Herbal/pharmacology ; Emodin/pharmacology ; Hippocampus/drug effects ; Proteomics ; Rats ; p38 Mitogen-Activated Protein Kinases/antagonists & inhibitors
Chemical Substances	Da-Cheng-Qi ; Drugs, Chinese Herbal ; p38 Mitogen-Activated Protein Kinases (EC 2.7.11.24) ; Emodin (KA46RNI6HN)
Language	English
Publishing date	2021-06-17
Publishing country	Germany
Document type	Journal Article
ZDB-ID	1205240-1
ISSN	1618-095X ; 0944-7113
ISSN (online)	1618-095X
ISSN	0944-7113
DOI	10.1016/j.phymed.2021.153630
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Article: [Effects of Xiao-Cheng-Qi decoction on brain edema and inflammatory factors in rats with severe traumatic brain injury].

Peng, Lingling / Wang, Jingbo / Pan, Yuzheng / Du, Yiheng / Huang, Guihua

Zhonghua wei zhong bing ji jiu yi xue

2022 Volume 33, Issue 11, Page(s) 1347–1352

Abstract: Objective: To observe the effects of the Chinese medicine prescription Xiao-Cheng-Qi decoction ...

Abstract	Objective: To observe the effects of the Chinese medicine prescription Xiao-Cheng-Qi decoction (XCQD) on acute brain edema and inflammatory factors in rats with severe traumatic brain injury (sTBI). Methods: A total of 108 male Sprague-Dawley (SD) rats were divided into control group, sham operation group, sTBI model group, and XCQD low, medium, high dose groups by random number table method, with 18 rats in each group. sTBI rat model was prepared according to the modified Freeney method. At 6 hours after injury, the XCQD low, medium, and high dose groups were given XCQD 1.80, 2.78, and 4.59 g/kg by gavage, respectively, and the other three groups were given the same amount of normal saline, once a day for 3 days. After 3 days of injury, rats in each group were sacrificed after the modified neurologic severity score (mNSS) assessed. Pathological changes of brain tissue were observed under light microscope after hematoxylin eosin (HE) staining, water content of brain tissue was measured by dry-wet specific gravity method, and the expressions of aquaporin 4 (AQP4), tumor necrosis factor-α (TNF-α) and interleukin-1β (IL-1β) in brain tissue were detected by Western blotting. Serum TNF-α and IL-1β levels were detected by enzyme linked immunosorbent assay (ELISA). Results: Compared with the normal group, the mNSS score of rats increased significantly, the structure of brain tissue was disordered, and pathological changes appeared such as inflammation, edema, pyknosis of nerve nuclei, water content, the protein expressions of AQP4, TNF-α and IL-1β in brain tissue, and the contents of TNF-α, IL-1β in serum were significantly increased. After XCQD intervention, the above indexes were significantly improved. Compared with sTBI model group, the mNSS score of XCQD medium and high dose groups significantly decreased (6.94±1.16, 6.88±1.02 vs. 8.61±1.09, both P < 0.05), and the pathological changes such as brain edema and inflammation were alleviated. Brain tissue water content, AQP4 protein expression and contents of serum TNF-α, IL-1β in XCQD low, medium, and high dose groups significantly decreased compared with sTBI model group [brain tissue water content: (78.25±0.71)%, (77.62±0.44)%, (76.70±0.74)% vs. (80.08±0.66)%; the expression of brain AQP4 protein (AQP4/β-actin): 0.86±0.13, 0.84±0.22, 0.65±0.13 vs. 1.08±0.14; serum TNF-α (ng/L): 106.34±15.07, 95.75±17.26, 89.00±17.36 vs. 141.96±29.47; serum IL-1β (ng/L): 90.41±12.88, 72.82±13.51, 71.32±16.79 vs. 128.57±22.56, respectively, all P < 0.05]. The protein expressions of TNF-α,IL-1β in brain tissue of XCQD medium and high dose groups also significantly decreased compared with sTBI model group [TNF-α (TNF-α/β-actin): 0.90±0.24, 0.79±0.35 vs. 1.17±0.15; IL-1β (IL-1β/β-actin): 0.91±0.21, 0.68±0.28 vs. 1.23±0.08, respectively, all P < 0.05]. Brain tissue water content, the expression of brain AQP4 protein, the levels of brain tissue and serum IL-1β in XCQD high dose group improved more significant than those of XCQD low dose group. Conclusions: XCQD can alleviate the acute brain edema in sTBI rats, and it is dose-dependent. The mechanism may be relevant to reduce the secondary inflammatory response of sTBI by inhibiting the expression of inflammatory factors TNF-α and IL-1β.
MeSH term(s)	Animals ; Brain Edema/drug therapy ; Brain Injuries, Traumatic/drug therapy ; Inflammation/drug therapy ; Male ; Rats ; Rats, Sprague-Dawley ; Tumor Necrosis Factor-alpha
Chemical Substances	Tumor Necrosis Factor-alpha
Language	Chinese
Publishing date	2022-01-03
Publishing country	China
Document type	Journal Article
ISSN	2095-4352
ISSN	2095-4352
DOI	10.3760/cma.j.cn121430-20210709-01030
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