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  1. Article ; Online: Human Papillomavirus Vaccination and Age at First Sexual Activity, National Health and Nutrition Examination Survey.

    Petrosky, Emiko Y / Liu, Gui / Hariri, Susan / Markowitz, Lauri E

    Clinical pediatrics

    2016  Volume 56, Issue 4, Page(s) 363–370

    Abstract: The National Health and Nutrition Examination Survey (NHANES) collects information on human papillomavirus (HPV) vaccination history as well as sexual activity. We evaluated data from NHANES to assess report of HPV vaccination with ≥1 dose and 3 doses ... ...

    Abstract The National Health and Nutrition Examination Survey (NHANES) collects information on human papillomavirus (HPV) vaccination history as well as sexual activity. We evaluated data from NHANES to assess report of HPV vaccination with ≥1 dose and 3 doses among females and males aged 11 to 26 years during 2007-2014. We also examined age at first vaccine dose and age at first sexual activity among females aged 14 to 26 years. Vaccination significantly increased in females aged 13 to 26 years, but not among 11- to 12-year-old girls, and remained low for both females and males. In NHANES 2011-2014, among females with known age at first vaccine dose, 43.1% reported having had sex before or in the same year they received their first HPV vaccine, and this varied by race/ethnicity. Clinicians should provide strong recommendations consistent with guidelines, including routine vaccination of girls and boys at age 11 or 12 years.
    MeSH term(s) Adolescent ; Adult ; Age Distribution ; Child ; Female ; Health Surveys/statistics & numerical data ; Humans ; Male ; Nutrition Surveys/statistics & numerical data ; Papillomavirus Infections/prevention & control ; Papillomavirus Vaccines/therapeutic use ; Sex Distribution ; Sexual Behavior/statistics & numerical data ; Young Adult
    Chemical Substances Papillomavirus Vaccines
    Language English
    Publishing date 2016-10-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 207678-0
    ISSN 1938-2707 ; 0009-9228
    ISSN (online) 1938-2707
    ISSN 0009-9228
    DOI 10.1177/0009922816660541
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Is vaccine type seropositivity a marker for human papillomavirus vaccination? National Health and Nutrition Examination Survey, 2003-2010.

    Petrosky, Emiko Y / Hariri, Susan / Markowitz, Lauri E / Panicker, Gitika / Unger, Elizabeth R / Dunne, Eileen F

    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases

    2015  Volume 33, Page(s) 137–141

    Abstract: Objective: Since 2006, human papillomavirus (HPV) vaccination has been routinely recommended for adolescent females in the USA. The quadrivalent vaccine induces long-term seropositivity to HPV 6/11/16, which may be useful as a marker for HPV vaccine ... ...

    Abstract Objective: Since 2006, human papillomavirus (HPV) vaccination has been routinely recommended for adolescent females in the USA. The quadrivalent vaccine induces long-term seropositivity to HPV 6/11/16, which may be useful as a marker for HPV vaccine coverage.
    Methods: We evaluated vaccine type seropositivity (i.e., seropositivity to HPV 6/11/16 with or without HPV18) among females aged 14-59 years participating in the 2003-2010 National Health and Nutrition Examination Survey (cross-sectional, nationally representative surveys). We compared pre-vaccine era (2003-2006) to vaccine era (2007-2010) seropositivity and assessed agreement between vaccine era seropositivity and reported vaccination by kappa statistic.
    Results: Seropositivity was 1.0% among 2151 females in the pre-vaccine era and 22.1% among 1420 females in the vaccine era (p < 0.001); 23.1% of vaccine era females reported receipt of one or more HPV vaccine dose. Seropositivity and reported vaccination had high agreement (kappa = 0.79; 95% confidence interval 0.74-0.84). Among seropositive females, 14.5% reported no vaccination.
    Conclusion: The increase in vaccine era seropositivity likely reflects vaccination uptake. Our study suggests seropositivity to HPV 6/11/16 may be a useful marker for vaccination coverage in adolescent and young adult females. Discordance between seropositivity and reported vaccination may be explained by inaccurate reporting and/or natural exposure to HPV.
    MeSH term(s) Adolescent ; Adult ; Antibodies, Viral/blood ; Biomarkers/blood ; Cross-Sectional Studies ; Female ; Health Surveys ; Humans ; Middle Aged ; Papillomaviridae/immunology ; Papillomavirus Infections/prevention & control ; Papillomavirus Vaccines/immunology ; Vaccination ; Young Adult
    Chemical Substances Antibodies, Viral ; Biomarkers ; Papillomavirus Vaccines
    Language English
    Publishing date 2015-01-14
    Publishing country Canada
    Document type Journal Article
    ZDB-ID 1331197-9
    ISSN 1878-3511 ; 1201-9712
    ISSN (online) 1878-3511
    ISSN 1201-9712
    DOI 10.1016/j.ijid.2015.01.010
    Database MEDical Literature Analysis and Retrieval System OnLINE

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