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  1. Book ; Online: Ethics and Drug Resistance: Collective Responsibility for Global Public Health

    Jamrozik, Euzebiusz / Selgelid, Michael

    (Public Health Ethics Analysis ; 5)

    2020  

    Author's details edited by Euzebiusz Jamrozik, Michael Selgelid
    Series title Public Health Ethics Analysis ; 5
    Keywords Bioethics ; Drug resistance ; Infectious diseases
    Subject code 171.7
    Language English
    Size 1 Online-Ressource (XVII, 448 p. 1 illus)
    Edition 1st ed. 2020
    Publisher Springer International Publishing ; Imprint: Springer
    Publishing place Cham
    Document type Book ; Online
    HBZ-ID HT020631344
    ISBN 978-3-030-27874-8 ; 9783030278731 ; 9783030278755 ; 9783030278762 ; 3-030-27874-3 ; 3030278735 ; 3030278751 ; 303027876X
    DOI 10.1007/978-3-030-27874-8
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book ; Online: Human Challenge Studies in Endemic Settings

    Jamrozik, Euzebiusz / Selgelid, Michael J.

    Ethical and Regulatory Issues

    (SpringerBriefs in Ethics)

    2021  

    Author's details by Euzebiusz Jamrozik, Michael J. Selgelid
    Series title SpringerBriefs in Ethics
    Keywords Bioethics ; Infectious diseases ; Vaccines ; Economic development
    Subject code 171.7
    Language English
    Size 1 Online-Ressource (XVII, 134 p. 1 illus)
    Edition 1st ed. 2021
    Publisher Springer International Publishing ; Imprint: Springer
    Publishing place Cham
    Document type Book ; Online
    HBZ-ID HT020567911
    ISBN 978-3-030-41480-1 ; 9783030414795 ; 9783030414818 ; 3-030-41480-9 ; 3030414795 ; 3030414817
    DOI 10.1007/978-3-030-41480-1
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Book ; Online: Ethics and Drug Resistance: Collective Responsibility for Global Public Health

    Jamrozik, Euzebiusz / Selgelid, Michael

    2020  

    Keywords Bio-ethics ; Pharmacology ; Infectious & contagious diseases ; Bioethics ; Drug Resistance ; Infectious Diseases ; Moral Philosophy and Applied Ethics ; Medical Microbiology ; Internal Medicine ; antimicrobial resistance ; public health ethics ; collective responsibility ; infectious disease ; global health ; hospital acquired infection ; animal ethics ; animal epidemiology ; TB resistance and human rights ; TB resistance in developing countries ; privacy and data collection ; ethics and AMR regulation ; ethics of drug development
    Size 1 electronic resource (448 pages)
    Publisher Springer Nature
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021027776
    ISBN 978-3-030-27874-8 ; 3-030-27874-3
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  4. Book ; Online: Human Challenge Studies in Endemic Settings

    Jamrozik, Euzebiusz / Selgelid, Michael J.

    2021  

    Abstract: This open access book provides an extensive review of ethical and regulatory issues related to human infection challenge studies, with a particular focus on the expansion of this type of research into endemic settings and/or low- and middle-income ... ...

    Abstract This open access book provides an extensive review of ethical and regulatory issues related to human infection challenge studies, with a particular focus on the expansion of this type of research into endemic settings and/or low- and middle-income countries (LMICs). Human challenge studies (HCS) involve the intentional infection of research participants, and this type of research is rapidly increasing in frequency worldwide. HCS are widely considered to be an especially promising approach to vaccine development, including for pathogens endemic to LMICs. However, challenge studies are sometimes controversial and raise complex ethical issues, some of which are especially salient in endemic and/or LMIC settings. Informed by qualitative interviews with experts in infectious diseases and bioethics, this book highlights areas of ethical consensus and controversy concerning this kind of research. As the first volume to focus on ethical issues associated with human challenge studies, it sets the agenda for further work in this important area of global health research; contributes to current debates in research ethics; and aims to inform regulatory policy and research practice. Insofar as it focuses on HCS in (endemic) settings where diseases are present and/or widespread, much of the analysis provided here is directly relevant to HCS involving pandemic diseases including COVID19
    Keywords Biology (General) ; Infectious and parasitic diseases ; Medicine (General) ; Colonies and colonization. Emigration and immigration. International migration
    Size 1 electronic resource (134 pages)
    Publisher Springer Nature
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT020677982
    ISBN 9783030414801 ; 3030414809
    DOI 10.1007/978-3-030-41480-1
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  5. Article ; Online: Public health ethics: critiques of the "new normal".

    Jamrozik, Euzebiusz

    Monash bioethics review

    2022  Volume 40, Issue 1, Page(s) 1–16

    Abstract: The global response to the recent coronavirus pandemic has revealed an ethical crisis in public health. This article analyses key pandemic public health policies in light of widely accepted ethical principles: the need for evidence, the least restrictive/ ...

    Abstract The global response to the recent coronavirus pandemic has revealed an ethical crisis in public health. This article analyses key pandemic public health policies in light of widely accepted ethical principles: the need for evidence, the least restrictive/harmful alternative, proportionality, equity, reciprocity, due legal process, and transparency. Many policies would be considered unacceptable according to pre-pandemic norms of public health ethics. There are thus significant opportunities to develop more ethical responses to future pandemics. This paper serves as the introduction to this Special Issue of Monash Bioethics Review and provides background for the other articles in this collection.
    MeSH term(s) Bioethics ; Coronavirus Infections/epidemiology ; Humans ; Pandemics/prevention & control ; Public Health
    Language English
    Publishing date 2022-09-27
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2510076-2
    ISSN 1836-6716 ; 1321-2753
    ISSN (online) 1836-6716
    ISSN 1321-2753
    DOI 10.1007/s40592-022-00163-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Herd immunity to endemic diseases: Historical concepts and implications for public health policy.

    Robertson, David / Heriot, George / Jamrozik, Euzebiusz

    Journal of evaluation in clinical practice

    2024  

    Abstract: Background: "Herd immunity" became a contested term during the COVID-19 pandemic. Although the term "herd immunity" is often used to refer to thresholds at which some diseases can be eliminated (e.g., due to mass vaccination), the term has multiple ... ...

    Abstract Background: "Herd immunity" became a contested term during the COVID-19 pandemic. Although the term "herd immunity" is often used to refer to thresholds at which some diseases can be eliminated (e.g., due to mass vaccination), the term has multiple referents. Different concepts of herd immunity have been relevant throughout the history of immunology and infectious disease epidemiology. For some diseases, herd immunity plays a role in the development of an endemic equilibrium, rather than elimination via threshold effects.
    Methods: We reviewed academic literature from 1920 to 2022, using historical and philosophical analysis to identify and develop relevant concepts of herd immunity.
    Results: This paper analyses the ambiguity surrounding the concept of herd immunity during the pandemic. We argue for the need to recapture a long-standing interpretation of this concept as one of the factors that leads to a dynamic endemic equilibrium between a host population and a mutating respiratory pathogen.
    Conclusions: Informed by the history of infectious disease epidemiology, we argue that understanding the concept in this way will help us manage both SARS-CoV-2 and hundreds of other seasonal respiratory pathogens with which we live but which have been disrupted due to sustained public health measures/non-pharmaceutical interventions targeting SARS-CoV-2.
    Language English
    Publishing date 2024-04-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 1327355-3
    ISSN 1365-2753 ; 1356-1294
    ISSN (online) 1365-2753
    ISSN 1356-1294
    DOI 10.1111/jep.13983
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: No Jab, No Pay and vaccine refusal in Australia: the jury is out.

    Jamrozik, Euzebiusz

    The Medical journal of Australia

    2018  Volume 207, Issue 9, Page(s) 407

    MeSH term(s) Australia ; Mandatory Programs ; Treatment Refusal ; Vaccination ; Vaccination Refusal
    Language English
    Publishing date 2018-01-11
    Publishing country Australia
    Document type Letter ; Comment
    ZDB-ID 186082-3
    ISSN 1326-5377 ; 0025-729X
    ISSN (online) 1326-5377
    ISSN 0025-729X
    DOI 10.5694/mja17.00479
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Moralization and Mismoralization in Public Health.

    Kraaijeveld, Steven R / Jamrozik, Euzebiusz

    Medicine, health care, and philosophy

    2022  Volume 25, Issue 4, Page(s) 655–669

    Abstract: Moralization is a social-psychological process through which morally neutral issues take on moral significance. Often linked to health and disease, moralization may sometimes lead to good outcomes; yet moralization is often detrimental to individuals and ...

    Abstract Moralization is a social-psychological process through which morally neutral issues take on moral significance. Often linked to health and disease, moralization may sometimes lead to good outcomes; yet moralization is often detrimental to individuals and to society as a whole. It is therefore important to be able to identify when moralization is inappropriate. In this paper, we offer a systematic normative approach to the evaluation of moralization. We introduce and develop the concept of 'mismoralization', which is when moralization is metaethically unjustified. In order to identify mismoralization, we argue that one must engage in metaethical analysis of moralization processes while paying close attention to the relevant facts. We briefly discuss one historical example (tuberculosis) and two contemporary cases related to COVID-19 (infection and vaccination status) that we contend to have been mismoralized in public health. We propose a remedy of de-moralization that begins by identifying mismoralization and that proceeds by neutralizing inapt moral content. De-moralization calls for epistemic and moral humility. It should lead us to pull away from our tendency to moralize-as individuals and as social groups-whenever and wherever moralization is unjustified.
    MeSH term(s) Humans ; Public Health ; COVID-19/epidemiology ; Morals
    Language English
    Publishing date 2022-08-31
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1440052-2
    ISSN 1572-8633 ; 1386-7423
    ISSN (online) 1572-8633
    ISSN 1386-7423
    DOI 10.1007/s11019-022-10103-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Ethics and antibiotic resistance.

    Jamrozik, Euzebiusz / Heriot, George S

    British medical bulletin

    2022  Volume 141, Issue 1, Page(s) 4–14

    Abstract: Introduction or background: Antibiotic resistance raises ethical issues due to the severe and inequitably distributed consequences caused by individual actions and policies.: Sources of data: Synthesis of ethical, scientific and clinical literature.!# ...

    Abstract Introduction or background: Antibiotic resistance raises ethical issues due to the severe and inequitably distributed consequences caused by individual actions and policies.
    Sources of data: Synthesis of ethical, scientific and clinical literature.
    Areas of agreement: Ethical analyses have focused on the moral responsibilities of patients to complete antibiotic courses, resistance as a tragedy of the commons and attempts to limit use through antibiotic stewardship.
    Areas of controversy: Each of these analyses has significant limitations and can result in self-defeating or overly narrow implications for policy.
    Growing points: More complex analyses focus on ethical implications of ubiquitous asymptomatic carriage of resistant bacteria, non-linear outcomes within and between patients over time and global variation in resistant disease burdens.
    Areas timely for developing research: Neglected topics include the harms of antibiotic use, including off-target effects on the human microbiome, and the lack of evidence guiding most antibiotic prescription decisions.
    MeSH term(s) Anti-Bacterial Agents/therapeutic use ; Drug Resistance, Microbial ; Humans ; Morals
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2022-02-04
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 213294-1
    ISSN 1471-8391 ; 0007-1420
    ISSN (online) 1471-8391
    ISSN 0007-1420
    DOI 10.1093/bmb/ldab030
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Ethics of antibiotic allergy.

    Xiang, Yu Yi / Heriot, George S / Jamrozik, Euzebiusz

    Journal of medical ethics

    2023  Volume 50, Issue 1, Page(s) 39–44

    Abstract: Antibiotic allergies are commonly reported among patients, but most do not experience reactions on rechallenge with the same agents. These reported allergies complicate management of infections in patients labelled as having penicillin allergy, including ...

    Abstract Antibiotic allergies are commonly reported among patients, but most do not experience reactions on rechallenge with the same agents. These reported allergies complicate management of infections in patients labelled as having penicillin allergy, including serious infections where penicillin-based antibiotics are the first-line (most effective and least toxic) treatment option. Allergy labels are rarely questioned in clinical practice, with many clinicians opting for inferior second-line antibiotics to avoid a perceived risk of allergy. Reported allergies thereby can have significant impacts on patients and public health, and present major ethical challenges. Antibiotic allergy testing has been described as a strategy to circumvent this dilemma, but it carries limitations that often make it less feasible in patients with acute infections or in community settings that lack access to allergy testing. This article provides an empirically informed ethical analysis of key considerations in this clinical dilemma, using
    MeSH term(s) Humans ; Bacteremia/complications ; Bacteremia/drug therapy ; Staphylococcal Infections/complications ; Staphylococcal Infections/drug therapy ; Staphylococcus aureus ; Anti-Bacterial Agents/adverse effects ; Penicillins/adverse effects ; Drug Hypersensitivity/complications ; Drug Hypersensitivity/drug therapy ; Hypersensitivity/complications ; Hypersensitivity/drug therapy
    Chemical Substances Anti-Bacterial Agents ; Penicillins
    Language English
    Publishing date 2023-12-14
    Publishing country England
    Document type Journal Article
    ZDB-ID 194927-5
    ISSN 1473-4257 ; 0306-6800
    ISSN (online) 1473-4257
    ISSN 0306-6800
    DOI 10.1136/jme-2022-108648
    Database MEDical Literature Analysis and Retrieval System OnLINE

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