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  1. Artikel ; Online: Evaluating the World Health Organization's SkinNTDs App as a Training Tool for Skin Neglected Tropical Diseases in Ghana and Kenya: Cross-Sectional Study.

    Cano, Mireia / Ruiz-Postigo, José A / Macharia, Paul / Ampem Amoako, Yaw / Odame Phillips, Richard / Kinyeru, Esther / Carrion, Carme

    Journal of medical Internet research

    2024  Band 26, Seite(n) e51628

    Abstract: Background: Neglected tropical diseases (NTDs) affect over 1.5 billion people worldwide, primarily impoverished populations in low- and middle-income countries. Skin NTDs, a significant subgroup, manifest primarily as skin lesions and require extensive ... ...

    Abstract Background: Neglected tropical diseases (NTDs) affect over 1.5 billion people worldwide, primarily impoverished populations in low- and middle-income countries. Skin NTDs, a significant subgroup, manifest primarily as skin lesions and require extensive diagnosis and treatment resources, including trained personnel and financial backing. The World Health Organization has introduced the SkinNTDs app, a mobile health tool designed to train and be used as a decision support tool for frontline health care workers. As most digital health guidelines prioritize the thorough evaluation of mobile health interventions, it is essential to conduct a rigorous and validated assessment of this app.
    Objective: This study aims to assess the usability and user experience of World Health Organization SkinNTDs app (version 3) as a capacity-building tool and decision-support tool for frontline health care workers.
    Methods: A cross-sectional study was conducted in Ghana and Kenya. Frontline health care workers dealing with skin NTDs were recruited through snowball sampling. They used the SkinNTDs app for at least 5 days before completing a web-based survey containing demographic variables and the user version of the Mobile Application Rating Scale (uMARS), a validated scale for assessing health apps. A smaller group of participants took part in semistructured interviews and one focus group. Quantitative data were analyzed using SPSS with a 95% CI and P≤.05 for statistical significance and qualitative data using ATLAS.ti to identify attributes, cluster themes, and code various dimensions that were explored.
    Results: Overall, 60 participants participated in the quantitative phase and 17 in the qualitative phase. The SkinNTDs app scored highly on the uMARS questionnaire, with an app quality mean score of 4.02 (SD 0.47) of 5, a subjective quality score of 3.82 (SD 0.61) of 5, and a perceived impact of 4.47 (SD 0.56) of 5. There was no significant association between the app quality mean score and any of the categorical variables examined, according to Pearson correlation analysis; app quality mean score vs age (P=.37), sex (P=.70), type of health worker (P=.35), country (P=.94), work context (P=.17), frequency of dealing with skin NTDs (P=.09), and dermatology experience (P=.63). Qualitative results echoed the quantitative outcomes, highlighting the ease of use, the offline functionality, and the potential utility for frontline health care workers in remote and resource-constrained settings. Areas for improvement were identified, such as enhancing the signs and symptoms section.
    Conclusions: The SkinNTDs app demonstrates notable usability and user-friendliness. The results indicate that the app could play a crucial role in improving capacity building of frontline health care workers dealing with skin NTDs. It could be improved in the future by including new features such as epidemiological context and direct contact with experts. The possibility of using the app as a diagnostic tool should be considered.
    International registered report identifier (irrid): RR2-10.2196/39393.
    Mesh-Begriff(e) Humans ; Cross-Sectional Studies ; Ghana ; Kenya ; Mobile Applications ; World Health Organization ; Female ; Adult ; Male ; Neglected Diseases ; Skin Diseases ; Middle Aged ; Tropical Medicine/methods ; Health Personnel/statistics & numerical data ; Surveys and Questionnaires
    Sprache Englisch
    Erscheinungsdatum 2024-04-30
    Erscheinungsland Canada
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2028830-X
    ISSN 1438-8871 ; 1438-8871
    ISSN (online) 1438-8871
    ISSN 1438-8871
    DOI 10.2196/51628
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel: Prostate-specific antigen for prediction of skeletal metastases on bone scintigraphy in prostate cancer.

    Hammond, Emmanuel Nii Boye / Amoako, Yaw Ampem / Laryea, Dennis Odai / Amoah, George

    World journal of nuclear medicine

    2021  Band 20, Heft 3, Seite(n) 327–328

    Sprache Englisch
    Erscheinungsdatum 2021-05-26
    Erscheinungsland Austria
    Dokumenttyp Journal Article
    ZDB-ID 2911903-0
    ISSN 1607-3312 ; 1450-1147
    ISSN (online) 1607-3312
    ISSN 1450-1147
    DOI 10.4103/wjnm.wjnm_129_20
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: Prostate-specific antigen for prediction of skeletal metastases on bone scintigraphy in prostate cancer

    Emmanuel Nii Boye Hammond / Yaw Ampem Amoako / Dennis Odai Laryea / George Amoah

    World Journal of Nuclear Medicine, Vol 20, Iss 3, Pp 327-

    2021  Band 328

    Schlagwörter Medical physics. Medical radiology. Nuclear medicine ; R895-920
    Sprache Englisch
    Erscheinungsdatum 2021-01-01T00:00:00Z
    Verlag Wolters Kluwer Medknow Publications
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  4. Artikel ; Online: Prevalence and determinants of impetigo in Ghana: a cross-sectional study.

    Amoako, Yaw Ampem / Laryea, Dennis Odai / Agbanyo, Abigail / Agbavor, Bernadette / Oppong, Michael Ntiamoah / Kyem, Gloria / Abass, Kabiru Mohammed / van Bentum, Renee / Phillips, Richard Odame / Stienstra, Ymkje

    BMC infectious diseases

    2024  Band 24, Heft 1, Seite(n) 349

    Abstract: Introduction: Skin diseases such as impetigo pose a significant public health challenge in low resource settings. Despite this, there is a dearth of epidemiological data on the prevalence of this condition in Ghana.: Methods: We conducted a cross ... ...

    Abstract Introduction: Skin diseases such as impetigo pose a significant public health challenge in low resource settings. Despite this, there is a dearth of epidemiological data on the prevalence of this condition in Ghana.
    Methods: We conducted a cross sectional study in three settings in Ghana: community members in East Mamprusi district in the North East region, a secondary school in Sekyere East district, and inmates of the Kumasi central prisons both in the Ashanti region. Following a period of training, we performed a standardised skin examination on each participant to assess for scabies and impetigo. We calculated the prevalence of each skin condition and investigated determinants of impetigo.
    Results/ findings: Of the 1327 participants [males 64.1% and median age 22 (16-29) years], 746 (56.2%) had scabies and 186 (14%) had impetigo which was usually very mild or mild in severity. Most participants with impetigo also had scabies (161/186, 86.6%). Having an itch [RR 6.05 (95% CI 2.53-14.47)], presence of scabies burrows [RR 1.99 (95% CI 1.54-2.59)], clinical scabies [RR 3.15 (2.11-4.72)] or being in preschool [RR 4.56 (1.78-11.67)] increased the risk for impetigo. A combination of the presence of clinical scabies, age, sex and itch most accurately predicted the odds of having impetigo.
    Conclusions: There is substantial burden of impetigo and scabies in Ghana. There is a need to institute measures to improve detection and control of these common dermatoses as part of Universal Health Coverage package to reduce the scourge of the diseases in this setting.
    Mesh-Begriff(e) Child, Preschool ; Male ; Humans ; Young Adult ; Adult ; Impetigo/epidemiology ; Cross-Sectional Studies ; Scabies/epidemiology ; Prevalence ; Ghana/epidemiology
    Sprache Englisch
    Erscheinungsdatum 2024-03-26
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 2041550-3
    ISSN 1471-2334 ; 1471-2334
    ISSN (online) 1471-2334
    ISSN 1471-2334
    DOI 10.1186/s12879-024-09242-y
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Artikel ; Online: Traditional healers' perception on scabies causation and management in Ghana.

    Tehrani, Jian M / Vos, Ingmar A / Kisabacak, Robin / Topper, Marten K / Steinhorst, Jonathan / Phillips, Richard Odame / Abass, Kabiru Mohammed / Osei-Mireku, Samuel / Anokye, Charles Owusu / Adu Poku, Joseph K / Stienstra, Ymkje / Amoako, Yaw Ampem

    Tropical medicine & international health : TM & IH

    2024  

    Abstract: Introduction: Scabies is an underdiagnosed skin infestation caused by the Sarcoptes scabiei mite. The infection causes severe itching and a skin rash but can be effectively treated using topical or systemic drugs. Scabies outbreaks are commonly reported ...

    Abstract Introduction: Scabies is an underdiagnosed skin infestation caused by the Sarcoptes scabiei mite. The infection causes severe itching and a skin rash but can be effectively treated using topical or systemic drugs. Scabies outbreaks are commonly reported in resource-poor countries, including Ghana. Traditional healers play an important role in primary care in rural areas. The role of these traditional healers in the management of scabies has so far not been explored. The aim of this study was therefore to investigate the perceptions of traditional healers regarding the causation and management of scabies.
    Methods: A phenomenological qualitative approach was employed. Traditional healers in the Asante Akim North and Central districts in Ghana were approached with an interview request. Using a semi-structured interview protocol, 15 traditional healers were interviewed. The results were coded and analysed, after which seven themes were extrapolated.
    Results: Scabies infections were frequently reported by traditional healers. Itching and skin rash were unanimously regarded as the major symptoms of scabies. The majority acknowledged the infectious nature of scabies, but no participant reported the causative organism. A dichotomous disease classification was noted, consisting of 'natural' and 'spiritual' variants each with a unique disease profile and management requirements, as reported by the traditional healers. All but two traditional healers reported to treat scabies using almost exclusively herbs and spiritual rituals.
    Conclusion: The majority of traditional healers were open to collaboration with allopathic healthcare providers. Collaboration could broaden the primary care network in rural areas, but mistrust and lack of transparency form potential barriers to collaboration. We, therefore, emphasise the need for additional efforts to investigate strategies for future collaboration.
    Sprache Englisch
    Erscheinungsdatum 2024-04-10
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 1314080-2
    ISSN 1365-3156 ; 1360-2276
    ISSN (online) 1365-3156
    ISSN 1360-2276
    DOI 10.1111/tmi.13989
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  6. Artikel ; Online: Clinical and microbiological predictors of healing in Buruli ulcer disease.

    Agbavor, Bernadette / Agbanyo, Abigail / Loglo, Aloysius Dzigbordi / Antwi, Philemon Boasiako / Ackam, Nancy / Adjei, Jonathan / Frimpong, Venus / Boampong, Kwadwo / Frimpong, Michael / Addo, Matthew Glover / Wansbrough-Jones, Mark / Amoako, Yaw Ampem / Phillips, Richard Odame

    Journal of clinical tuberculosis and other mycobacterial diseases

    2024  Band 34, Seite(n) 100415

    Abstract: Introduction: Wound measurements are relevant in monitoring the rate of healing (RoH) and may predict time to healing. Predicting the time to healing can help improve the management of Buruli ulcer. We examine three methods for the determination of RoH ... ...

    Abstract Introduction: Wound measurements are relevant in monitoring the rate of healing (RoH) and may predict time to healing. Predicting the time to healing can help improve the management of Buruli ulcer. We examine three methods for the determination of RoH and their use as predictors of time to healing.
    Methods: Lesion measurements of Buruli ulcer patients treated from 2007 to 2022 were obtained with acetate sheet tracings (2D) or Aranz software (3D) fortnightly. RoH was determined using the absolute area, percentage area reduction and linear methods at 4 weeks post onset of antibiotic treatment. Predicted time to healing was compared to the actual healing time. Baseline characteristics were assessed for associations with healing.
    Results: All three methods for calculating the RoH significantly distinguished between fast and slow healers (p < 0.0001). The predicted healing time using the linear method was comparable to the actual healing time for fast healers (p = 0.34). The RoH was influenced by the form of lesion, with plaques [OR 2.19 5 %CI (1.2-3.6), p = 0.009], and oedemas [OR 8.5; 95 %CI (1.9--36.9), p = 0.004] being associated with delayed healing. The proportion of patients with paradoxical reactions 16 % vs 3 %, p < 0.0001), higher baseline bacterial load (75/104;72 % vs 21/47;45 %, p = 0.001) and delayed clearance of viable organisms (71/104;68 % vs 9/47;19 %, p < 0.0001) was higher in the slow healers than the fast healers.
    Conclusion: Predicted healing rates were comparatively lower for slow healers than fast healers. Baseline characteristics associated with healing can be explored for an improved disease management plan to reduce patient and caregiver anxiety.
    Sprache Englisch
    Erscheinungsdatum 2024-01-06
    Erscheinungsland England
    Dokumenttyp Journal Article
    ISSN 2405-5794
    ISSN (online) 2405-5794
    DOI 10.1016/j.jctube.2024.100415
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  7. Artikel ; Online: Implementation of an integrated control programme for neglected tropical diseases of the skin in Ghana: The essential role of the laboratory.

    Agbanyo, Abigail / Agbavor, Bernadette / Gyabaah, Solomon / Oppong, Michael Ntiamoah / Dornu, Olivia / Antwi, Philemon Boasiako / Loglo, Aloysius Dzigbordi / Abass, Kabiru Mohammed / Amofa, George / Kotey, Nana Konama / Quao, Benedict / Frimpong, Michael / Asiedu, Kingsley / Amoako, Yaw Ampem / Phillips, Richard Odame

    Journal of clinical tuberculosis and other mycobacterial diseases

    2024  Band 35, Seite(n) 100442

    Abstract: ... Buruli ulcer (BU), and yaws in seven selected districts in Ghana.: Methods: Actions implemented from July ... for trained health workers, laboratory confirmation of BU and yaws samples and providing results ... of 18,683 (including suspected BU 976; suspected yaws 10,995) individuals were screened for BU and yaws ...

    Abstract Introduction: In this study, we report on findings from approaches used, the outcomes and the lessons learnt from the laboratory support provided for integrated control of skin NTDs including Buruli ulcer (BU), and yaws in seven selected districts in Ghana.
    Methods: Actions implemented from July 2018 to October 2022 included; training district-level health workers on specimen collection, storage, and transport to laboratories, integrated case searches, continual monitoring and supervision for trained health workers, laboratory confirmation of BU and yaws samples and providing results of the analysed samples to guide decision making. Descriptive analysis of data was performed.
    Results: A total of 18,683 (including suspected BU 976; suspected yaws 10,995) individuals were screened for BU and yaws. Of 976 suspected BU cases, 16.8% [median (IQR) age 24 (12.0-37.8) years] were confirmed positive by IS2404 PCR; BU mostly presented as ulcers (78.7%); category I (37.2%) and category II (36%). 480 individuals (4.4%) had DPP positive yaws. Multiplex PCR analysis of 75 selected DPP positive cases identified; 7 DPP positive yaws cases as
    Conclusion: The implementation of integrated diagnostic confirmation for skin NTDs is feasible with provision of timely results within a week. Multiplex diagnostic tools differentiated
    Sprache Englisch
    Erscheinungsdatum 2024-04-20
    Erscheinungsland England
    Dokumenttyp Journal Article
    ISSN 2405-5794
    ISSN (online) 2405-5794
    DOI 10.1016/j.jctube.2024.100442
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  8. Artikel ; Online: Stigma experiences, effects and coping among individuals affected by Buruli ulcer and yaws in Ghana.

    Tuwor, Ruth Dede / Mtuy, Tara B / Amoako, Yaw Ampem / Owusu, Lucy / Oppong, Michael Ntiamoah / Agbanyo, Abigail / Agbavor, Bernadette / Marks, Michael / Walker, Stephen L / Yeboah-Manu, Dorothy / Pullan, Rachel L / Dapaah, Jonathan Mensah / Phillips, Richard Odame / Palmer, Jennifer

    PLoS neglected tropical diseases

    2024  Band 18, Heft 4, Seite(n) e0012093

    Abstract: Background: Stigma related to skin neglected tropical diseases like Buruli ulcer (BU) and yaws has ... for integration in disease management. Within two districts in central Ghana, we explored stigma associated with BU and yaws ... In contrast, a high level of social acceptance was reported among yaws participants although some micro-level ...

    Abstract Background: Stigma related to skin neglected tropical diseases like Buruli ulcer (BU) and yaws has remained underexplored and existing studies are limited to individual diseases despite the WHO call for integration in disease management. Within two districts in central Ghana, we explored stigma associated with BU and yaws to understand overlaps and disease-specific nuances to help guide integrated interventions.
    Methodology/principal findings: In-depth interviews were conducted with 31 current or formerly affected individuals to assess the experiences, effects and coping strategies adopted to manage disease related stigma. Data were analysed along broad themes based on the sociological construct of macro and micro interaction and Goffman's treatise on stigma. Disapproving community labels fueled by misconceptions were noted among BU participants which contributed to macro stigma experiences, including exclusion, discrimination and avoidance. In contrast, a high level of social acceptance was reported among yaws participants although some micro-level stigma (anticipated, felt and self-stigma) were noted by individuals with both diseases. While younger participants experienced name-calling and use of derogatory words to address affected body parts, older participants and caregivers discussed the pain of public staring. Stigma experiences had negative consequences on psychosocial well-being, schooling, and social relations, particularly for BU affected people. Problem-focused strategies including confrontation, selective disclosure and concealment as well as emotion-focused strategies (religious coping and self-isolation) were noted.
    Conclusions and significance: The types and levels of stigma varied for BU and yaws. Stigma experiences also differed for adults and children in this setting and these differences should be accounted for in integrated interventions for these skin NTDs. School health programs need to prioritize educating school teachers about skin NTDs and the negative impact of stigma on the wellbeing of children.
    Mesh-Begriff(e) Humans ; Buruli Ulcer/psychology ; Ghana ; Social Stigma ; Female ; Male ; Adult ; Adaptation, Psychological ; Middle Aged ; Young Adult ; Adolescent ; Yaws/psychology ; Child ; Aged
    Sprache Englisch
    Erscheinungsdatum 2024-04-29
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2429704-5
    ISSN 1935-2735 ; 1935-2735
    ISSN (online) 1935-2735
    ISSN 1935-2735
    DOI 10.1371/journal.pntd.0012093
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  9. Artikel ; Online: Beliefs, attitudes and practices towards scabies in central Ghana.

    Yaw Ampem Amoako / Lotte Suzanne van Rietschoten / Michael Ntiamoah Oppong / Kwabena Oppong Amoako / Kabiru Mohammed Abass / Bernard Akoto Anim / Dennis Odai Laryea / Richard Odame Phillips / Ymkje Stienstra

    PLoS Neglected Tropical Diseases, Vol 17, Iss 2, p e

    2023  Band 0011175

    Abstract: Background Scabies commonly affects poor populations in low-middle-income countries. The WHO has advocated for country-driven and country-owned control strategies. Knowledge of context specific issues will be important for design and implementation of ... ...

    Abstract Background Scabies commonly affects poor populations in low-middle-income countries. The WHO has advocated for country-driven and country-owned control strategies. Knowledge of context specific issues will be important for design and implementation of scabies control interventions. We aimed to assess beliefs, attitudes and practices towards scabies in central Ghana. Methodology/principal findings Data was collected via semi-structured questionnaires for people who had active scabies or scabies in the past year and people who never had scabies in the past. The questionnaire covered several domains: knowledge about the causes and risk factors; perceptions towards stigmatisation and consequences of scabies in daily life; and treatment practices. Out of 128 participants, 67 were in the (former) scabies group and had a mean age of 32.3 ± 15.6 years. Overall scabies group participants less often indicated a factor to predispose to scabies than community controls; only 'family/friends contacts' was more often mentioned in the scabies group. Scabies causation was attributed to poor hygiene, traditional beliefs, heredity and drinking water. Individuals with scabies delay care seeking (median time from symptom onset to visiting the health centre was 21 [14 - 30] days) and this delay is enhanced by their beliefs (like witchcraft and curses) and a perception of limited disease severity. Compared to past scabies participants in the dermatology clinic, participants with past scabies in the community tended to have a longer delay (median [IQR] 30 [14-48.8] vs 14 [9.5-30] days, p = 0.002). Scabies was associated with health consequences, stigma, and loss of productivity. Conclusion/significance Early diagnosis and effective treatment of scabies can lead to persons less frequently associating scabies with witchcraft and/ or curses. There is the need to enhance health education to promote early care seeking, enhance knowledge of communities on impact and dispel negative perceptions about scabies in Ghana.
    Schlagwörter Arctic medicine. Tropical medicine ; RC955-962 ; Public aspects of medicine ; RA1-1270
    Sprache Englisch
    Erscheinungsdatum 2023-02-01T00:00:00Z
    Verlag Public Library of Science (PLoS)
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  10. Artikel ; Online: Beliefs, attitudes and practices towards scabies in central Ghana.

    Amoako, Yaw Ampem / van Rietschoten, Lotte Suzanne / Oppong, Michael Ntiamoah / Amoako, Kwabena Oppong / Abass, Kabiru Mohammed / Anim, Bernard Akoto / Laryea, Dennis Odai / Phillips, Richard Odame / Stienstra, Ymkje

    PLoS neglected tropical diseases

    2023  Band 17, Heft 2, Seite(n) e0011175

    Abstract: Background: Scabies commonly affects poor populations in low-middle-income countries. The WHO has advocated for country-driven and country-owned control strategies. Knowledge of context specific issues will be important for design and implementation of ... ...

    Abstract Background: Scabies commonly affects poor populations in low-middle-income countries. The WHO has advocated for country-driven and country-owned control strategies. Knowledge of context specific issues will be important for design and implementation of scabies control interventions. We aimed to assess beliefs, attitudes and practices towards scabies in central Ghana.
    Methodology/principal findings: Data was collected via semi-structured questionnaires for people who had active scabies or scabies in the past year and people who never had scabies in the past. The questionnaire covered several domains: knowledge about the causes and risk factors; perceptions towards stigmatisation and consequences of scabies in daily life; and treatment practices. Out of 128 participants, 67 were in the (former) scabies group and had a mean age of 32.3 ± 15.6 years. Overall scabies group participants less often indicated a factor to predispose to scabies than community controls; only 'family/friends contacts' was more often mentioned in the scabies group. Scabies causation was attributed to poor hygiene, traditional beliefs, heredity and drinking water. Individuals with scabies delay care seeking (median time from symptom onset to visiting the health centre was 21 [14 - 30] days) and this delay is enhanced by their beliefs (like witchcraft and curses) and a perception of limited disease severity. Compared to past scabies participants in the dermatology clinic, participants with past scabies in the community tended to have a longer delay (median [IQR] 30 [14-48.8] vs 14 [9.5-30] days, p = 0.002). Scabies was associated with health consequences, stigma, and loss of productivity.
    Conclusion/significance: Early diagnosis and effective treatment of scabies can lead to persons less frequently associating scabies with witchcraft and/ or curses. There is the need to enhance health education to promote early care seeking, enhance knowledge of communities on impact and dispel negative perceptions about scabies in Ghana.
    Mesh-Begriff(e) Humans ; Adolescent ; Young Adult ; Adult ; Middle Aged ; Scabies/epidemiology ; Scabies/prevention & control ; Ghana/epidemiology ; Health Knowledge, Attitudes, Practice ; Patient Acceptance of Health Care ; Risk Factors
    Sprache Englisch
    Erscheinungsdatum 2023-02-22
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 2429704-5
    ISSN 1935-2735 ; 1935-2735
    ISSN (online) 1935-2735
    ISSN 1935-2735
    DOI 10.1371/journal.pntd.0011175
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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