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Article ; Online: Acute inspiratory resistance training enhances endothelium-dependent dilation and retrograde shear rate in healthy young adults.

Tavoian, Dallin / Mazzone, Josie L / Craighead, Daniel H / Bailey, E Fiona

2024 Volume 12, Issue 3, Page(s) e15943

Abstract: ... cycle phase, and converted into SRs. FMD improved 10 min post-IRT (+1.86 ± 0.61%; p = 0.025 ... but returned to baseline by 40 min post-IRT (p = 0.002). Anterograde SR decreased by 10% and retrograde SR ... increased 102% during resisted inspiration, relative to baseline SR (p < 0.001). Anterograde SR increased ...

Abstract	Inspiratory resistance training (IRT) yields significant reductions in resting blood pressure and improves vascular endothelial function. Our objective was to quantify the acute effects of IRT on brachial artery flow-mediated dilation (FMD) and shear rates (SRs) in healthy men and women. Twenty young adults (22.9 ± 3.4 years; 10 male, 10 female) completed a single bout of IRT or Rest condition in a randomized crossover design. Brachial artery FMD was performed before, 10 min after, and 40 min after the assigned condition. Brachial artery blood flow velocities were collected during IRT, separated by breathing cycle phase, and converted into SRs. FMD improved 10 min post-IRT (+1.86 ± 0.61%; p = 0.025) but returned to baseline by 40 min post-IRT (p = 0.002). Anterograde SR decreased by 10% and retrograde SR increased 102% during resisted inspiration, relative to baseline SR (p < 0.001). Anterograde SR increased by 7% in men and women (p < 0.001) and retrograde SR decreased by 12% in women but not men (p = 0.022) during unresisted expiration, relative to baseline SR. A single bout of IRT elicits a transient enhancement in FMD in both men and women. Acute IRT-related enhancements in SRs may contribute to sustained improvements in FMD that have been reported previously.
MeSH term(s)	Adult ; Female ; Humans ; Male ; Young Adult ; Blood Flow Velocity/physiology ; Brachial Artery/physiology ; Cross-Over Studies ; Dilatation ; Endothelium, Vascular/physiology ; Regional Blood Flow/physiology ; Resistance Training ; Stress, Mechanical ; Vasodilation/physiology
Language	English
Publishing date	2024-02-03
Publishing country	United States
Document type	Journal Article ; Randomized Controlled Trial
ZDB-ID	2724325-4
ISSN	2051-817X ; 2051-817X
ISSN (online)	2051-817X
ISSN	2051-817X
DOI	10.14814/phy2.15943
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: The ISQ-P tool: measuring stress associated with incontinence.

Yu, L C / Kaltreider, D L / Hu, T / Igou, J F / Craighead, W E

Journal of gerontological nursing

1989 Volume 15, Issue 2, Page(s) 9–15

Abstract: 1. ISQ-P is a useful tool in measuring psychological stress associated with urinary incontinence. 2 ... ISQ-P can be used in conjunction with bladder training programs. 3. Patients with urinary incontinence ...

Abstract	1. ISQ-P is a useful tool in measuring psychological stress associated with urinary incontinence. 2. ISQ-P can be used in conjunction with bladder training programs. 3. Patients with urinary incontinence show depressive symptoms, have somatic concerns regarding urinary incontinence, and exhibit a feeling of shame.
MeSH term(s)	Aged ; Aged, 80 and over ; Depression/etiology ; Female ; Humans ; Surveys and Questionnaires ; Urinary Incontinence, Stress/diagnosis ; Urinary Incontinence, Stress/psychology
Language	English
Publishing date	1989-02
Publishing country	United States
Document type	Journal Article
ZDB-ID	603140-7
ISSN	0098-9134
ISSN	0098-9134
DOI	10.3928/0098-9134-19890201-05
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Zs.B 2334: Show issues

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Article ; Online: The protective effects of Swedish COVID-19 pandemic strategies on adolescents' mental health: a longitudinal cohort study.

Lilja, Josefine L / Augustsson, Pia / Praetorius Björk, Marcus / Marteinsdottir, Ina / Craighead, W Edward / Örn Arnarson, Eiríkur / Sveinsdottir, Gudny / Wikberg, Carl

Scandinavian journal of public health

2024 , Page(s) 14034948241238836

Language	English
Publishing date	2024-03-22
Publishing country	Sweden
Document type	Journal Article
ZDB-ID	1475054-5
ISSN	1651-1905 ; 1403-4948
ISSN (online)	1651-1905
ISSN	1403-4948
DOI	10.1177/14034948241238836
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Zs.A 884: Show issues

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Article ; Online: Assessing in-session rumination and its effects on CBT for depression.

Kennedy, J C / Dunlop, B W / Craighead, L W / Nemeroff, C B / Mayberg, H S / Craighead, W E

Behaviour research and therapy

2022 Volume 159, Page(s) 104209

Abstract: ... the initial treatment session predicted higher levels of subsequent clinician-rated depressive symptoms (p ... at session 8 significantly predicted higher clinician-rated symptoms at end of treatment (p's < 0.02 ...

Abstract	The study evaluated if rumination of patients during therapy (i.e., in-session rumination) relates to whether or not they do less well in CBT treatment. We developed a reliably assessed in-session rumination observational measure and evaluated its relationship to depression over the course of CBT. Rated sessions came from 63 treatment-naïve patients with major depressive disorder who participated in CBT in the PReDICT study (Dunlop et al., 2017). In-session rumination was operationalized as repetitive, negative, and passive talking about depressive topics. Trained undergraduates rated the intensity and duration of in-session rumination occurring during 57 initial therapy sessions (i.e., session one) and 45 sessions in the middle of treatment (i.e., session eight). The observational ratings were sufficiently reliable (all ICCs > 0.69). Mixed model results indicated that greater intensity of in-session rumination during the initial treatment session predicted higher levels of subsequent clinician-rated depressive symptoms (p < .023). Regression results indicated that greater intensity and duration of in-session rumination at session 8 significantly predicted higher clinician-rated symptoms at end of treatment (p's < 0.02). In-session rumination intensity and duration were not, however, related to subsequent self-reported depressive symptoms. The results support efforts to identify which patients might benefit from rumination-specific interventions.
MeSH term(s)	Humans ; Depressive Disorder, Major/therapy ; Depression/therapy ; Depression/diagnosis ; Self Report
Language	English
Publishing date	2022-10-09
Publishing country	England
Document type	Journal Article
ZDB-ID	211997-3
ISSN	1873-622X ; 0005-7967
ISSN (online)	1873-622X
ISSN	0005-7967
DOI	10.1016/j.brat.2022.104209
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Zs.A 162: Show issues

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Article: 1987 H. P. Smith award lecture. Eyes for the epidemiologist: the pathologist's role in shaping our understanding of the asbestos-associated diseases.

Craighead, J E

American journal of clinical pathology

1988 Volume 89, Issue 2, Page(s) 281–287

Abstract: Asbestosis was first recognized as an entity at autopsy by a pathologist in 1900. Pathologists also discovered the unique relationship of mesothelioma and bronchogenic carcinoma with exposure to asbestos. The observations of preceding pathologists have ... ...

Abstract	Asbestosis was first recognized as an entity at autopsy by a pathologist in 1900. Pathologists also discovered the unique relationship of mesothelioma and bronchogenic carcinoma with exposure to asbestos. The observations of preceding pathologists have provided insights that have served as the basis for epidemiologic studies associating asbestos with disease in humans.
MeSH term(s)	Asbestos/adverse effects ; Asbestos/history ; Asbestosis/chemically induced ; Asbestosis/history ; Asbestosis/pathology ; Awards and Prizes ; Carcinoma, Bronchogenic/etiology ; Carcinoma, Bronchogenic/pathology ; England ; Epidemiology/history ; Germany ; History, 19th Century ; History, 20th Century ; Humans ; Lung Neoplasms/etiology ; Lung Neoplasms/pathology ; Mesothelioma/chemically induced ; Mesothelioma/pathology ; Pathology/history ; United States
Chemical Substances	Asbestos (1332-21-4)
Language	English
Publishing date	1988-02
Publishing country	England
Document type	Historical Article ; Journal Article ; Portrait
ZDB-ID	2944-0
ISSN	1943-7722 ; 0002-9173
ISSN (online)	1943-7722
ISSN	0002-9173
DOI	10.1093/ajcp/89.2.281
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Ud II Zs.91: Show issues

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Article ; Online: Day Case Local Anaesthetic Thoracoscopy

Megan Turner / Felicity Craighead / Joseph Donald MacKenzie / Avinash Aujayeb

Medical Sciences, Vol 11, Iss 23, p

Experience from 2 District General Hospitals in the United Kingdom

2023 Volume 23

Abstract: Background: Local anaesthetic thoracoscopy (LAT) can be a vital procedure for diagnosis of unexplained pleural effusions. Traditionally, poudrage for pleurodesis and insertion of a large bore drain necessitated admission. There has been a shift towards ... ...

Abstract	Background: Local anaesthetic thoracoscopy (LAT) can be a vital procedure for diagnosis of unexplained pleural effusions. Traditionally, poudrage for pleurodesis and insertion of a large bore drain necessitated admission. There has been a shift towards performing LAT as a day case procedure with indwelling pleural catheter (IPC) insertion. This was advocated during the COVID pandemic by the British Thoracic Society (BTS). To determine the feasibility of such pathways, continuous evaluations are required. Methods: All day case LAT procedures with IPC insertion, performed in theatre, were identified at two large district general hospitals (Northumbria HealthCare in the North East of England and Victoria Hospital, NHS Fife, in Scotland). Rapid pleurodesis with talc was not performed due to local staffing problems. All patients had their LAT in theatre under conscious sedation with a rigid scope. Demographics, clinical, radiological and histopathological characteristics and outcomes were collected. Results: 79 patients underwent day case LAT. The lung did not deflate, meaning biopsies were not enabled, in four of the patients. The mean age was 72 years (standard deviation 13). Fifty-five patients were male and twenty-four were female. The main diagnoses were lung cancers, mesotheliomas and fibrinous pleuritis with an overall diagnostic sensitivity of 93%. Other diagnoses were breast, tonsillar, unknown primary cancers and lymphomas. Seventy-three IPCs were simultaneously placed and, due to normal macroscopic appearances in two patients, two large bore drains were placed and removed within one hour of LAT termination. Sixty-six (88%) patients were discharged on the same day. Seven patients required admission: one for treatment of surgical emphysema, four because they lived alone, one for pain control and one for control of a cardiac arrythmia. Within 30 days, there were five IPC site infections with two resultant empyemas (9%), with no associated mortality. Two patients developed pneumonia requiring admission and one ...
Keywords	local anaesthetic thoracoscopy ; medical thoracoscopy ; indwelling pleural catheter ; Medicine ; R
Subject code	610
Language	English
Publishing date	2023-03-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Has Radiotherapy Been Successfully Implemented in Alberta's Small Cities? A Review of Alberta's Regional Cancer Centre Network from 2010-2020.

Craighead, Peter S / Ruether, Dean / Martens, Chandra / Grendarova, Petra

Current oncology (Toronto, Ont.)

2021 Volume 28, Issue 1, Page(s) 445–454

Abstract: The expansion of cancer services closer to home has become a major focus of publicly funded healthcare, with cancer organizations attempting to invest in smaller centers by integrating radiotherapy into these facilities. In Canada this has resulted in ... ...

Abstract	The expansion of cancer services closer to home has become a major focus of publicly funded healthcare, with cancer organizations attempting to invest in smaller centers by integrating radiotherapy into these facilities. In Canada this has resulted in Ontario, British Columbia and Alberta investing in 12 expanded regional centers over the past 20 years. Quebec, Manitoba and Nova Scotia have made similar investments. Alberta's three new centers opened in 2010, 2013 and 2021 (projected). This study examined improvements in wait times and patient throughput between 2010 and 2020, and highlighted strategies that will support the sustainability and growth of clinical activity through to 2030. Significant improvement in ready to treat wait times for radiotherapy have resulted from opening two centers, and the provincial throughput for patients requiring systemic or radiotherapy has gone up by 16%. A patient satisfaction survey demonstrated that rural patients are happy with their care and desire the provision of more of their cancer treatment closer to home. An expert panel provided recommendations on what needs to be done to stabilize recruitment and retention.
MeSH term(s)	Alberta ; British Columbia ; Cities ; Humans ; Neoplasms/radiotherapy ; Surveys and Questionnaires
Language	English
Publishing date	2021-01-13
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	1236972-x
ISSN	1718-7729 ; 1198-0052
ISSN (online)	1718-7729
ISSN	1198-0052
DOI	10.3390/curroncol28010047
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Zs.A 4305: Show issues

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Article ; Online: A novel camera trapping method for individually identifying pumas by facial features

Peter D. Alexander / Derek J. Craighead

Ecology and Evolution, Vol 12, Iss 1, Pp n/a-n/a (2022)

2022

Abstract: ... that included the accessory (n = 208, χ2 = 43.23, p ≤ .001). To evaluate if puma faces improve photo‐ID ...

Abstract	Abstract Camera traps (CTs), used in conjunction with capture–mark–recapture analyses (CMR; photo‐CMR), are a valuable tool for estimating abundances of rare and elusive wildlife. However, a critical requirement of photo‐CMR is that individuals are identifiable in CT images (photo‐ID). Thus, photo‐CMR is generally limited to species with conspicuous pelage patterns (e.g., stripes or spots) using lateral‐view images from CTs stationed along travel paths. Pumas (Puma concolor) are an elusive species for which CTs are highly effective at collecting image data, but their suitability to photo‐ID is controversial due to their lack of pelage markings. For a wide range of taxa, facial features are useful for photo‐ID, but this method has generally been limited to images collected with traditional handheld cameras. Here, we evaluate the feasibility of using puma facial features for photo‐ID in a CT framework. We consider two issues: (1) the ability to capture puma facial images using CTs, and (2) whether facial images improve human ability to photo‐ID pumas. We tested a novel CT accessory that used light and sound to attract the attention of pumas, thereby collecting face images for use in photo‐ID. Face captures rates increased at CTs that included the accessory (n = 208, χ2 = 43.23, p ≤ .001). To evaluate if puma faces improve photo‐ID, we measured the inter‐rater agreement of 5 independent assessments of photo‐ID for 16 of our puma face capture events. Agreement was moderate to good (Fleiss’ kappa = 0.54, 95% CI = 0.48–0.60), and was 92.90% greater than a previously published kappa using conventional CT methods. This study is the first time that such a technique has been used for photo‐ID, and we believe a promising demonstration of how photo‐ID may be feasible for an elusive but unmarked species.
Keywords	camera traps ; facial recognition ; novel techniques ; photo‐ID ; population monitoring ; Puma concolor ; Ecology ; QH540-549.5
Subject code	333
Language	English
Publishing date	2022-01-01T00:00:00Z
Publisher	Wiley
Document type	Article ; Online
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Article ; Online: Menthol-Induced Cutaneous Vasodilation Is Preserved in Essential Hypertensive Men and Women.

Craighead, Daniel H / Alexander, Lacy M

American journal of hypertension

2017 Volume 30, Issue 12, Page(s) 1156–1162

Abstract: ... in both the normotensive and hypertensive groups (menthol doses 100, 250, and 500 mM; all P < 0.05 compared to baseline ... There were no differences between groups (P = 0.58, main effect). There was no effect of either NOS or ...

Abstract	Background: Menthol is a selective transient receptor potential melastatin 8 (TRPM8) channel agonist that induces cutaneous vasodilation in young, normotensive men and women through nitric oxide synthase (NOS)-, endothelium-derived hyperpolarizing factor (EDHF)-, and sensory nerve-mediated mechanisms. Microvascular dysfunction is present in essential hypertension and whether menthol induces vasodilation is men and women with essential hypertension is equivocal. Methods: Four intradermal microdialysis fibers were placed in the forearm of 9 essential hypertensive and 10 age-matched normotensive control subjects. Sites were pretreated with lactated Ringer's (control), l-NAME (NOS inhibited), TEA (EDHF inhibited), and lidocaine (sensory nerve inhibited). The microdialysis fibers were then perfused with 7 increasing doses of menthol (0.1-500 mM). Red cell flux in response to menthol was measured with laser Doppler flowmetry. Data were normalized to mean arterial pressure and presented as a percentage of site-specific maximum vasodilation (%CVCmax). Results: At the control site, menthol caused vasodilation in both the normotensive and hypertensive groups (menthol doses 100, 250, and 500 mM; all P < 0.05 compared to baseline). There were no differences between groups (P = 0.58, main effect). There was no effect of either NOS or sensory nerve inhibition on menthol-induced vasodilation in the normotensive group; however, menthol-induced vasodilation was attenuated with NOS and sensory nerve inhibition in the hypertensive group. EDHF inhibition attenuated menthol-induced vasodilation in both groups. Conclusions: Menthol-induced vasodilation has NO, EDHF, and sensory nerve components. Menthol-induced cutaneous vasodilation is preserved in hypertensive subjects. However, the hypertensive subjects exhibited a loss of redundant vasodilator systems.
MeSH term(s)	Arterial Pressure/drug effects ; Capillaries/drug effects ; Dose-Response Relationship, Drug ; Enzyme Inhibitors/pharmacology ; Erythrocytes/drug effects ; Essential Hypertension/physiopathology ; Female ; Humans ; Laser-Doppler Flowmetry ; Male ; Menthol/pharmacology ; Middle Aged ; NG-Nitroarginine Methyl Ester/pharmacology ; Nitric Oxide Synthase/antagonists & inhibitors ; Regional Blood Flow/drug effects ; Skin/blood supply ; TRPM Cation Channels/agonists ; Vasodilation/drug effects ; Vasodilator Agents/pharmacology
Chemical Substances	Enzyme Inhibitors ; TRPM Cation Channels ; TRPM8 protein, human ; Vasodilator Agents ; Menthol (1490-04-6) ; Nitric Oxide Synthase (EC 1.14.13.39) ; NG-Nitroarginine Methyl Ester (V55S2QJN2X)
Language	English
Publishing date	2017-10-14
Publishing country	United States
Document type	Journal Article
ZDB-ID	639383-4
ISSN	1941-7225 ; 1879-1905 ; 0895-7061
ISSN (online)	1941-7225 ; 1879-1905
ISSN	0895-7061
DOI	10.1093/ajh/hpx127
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Zs.A 2329: Show issues

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Article ; Online: Time-efficient, high-resistance inspiratory muscle strength training for cardiovascular aging.

Craighead, Daniel H / Freeberg, Kaitlin A / McCarty, Narissa P / Seals, Douglas R

Experimental gerontology

2021 Volume 154, Page(s) 111515

Abstract: Cardiovascular diseases (CVD) remain the leading cause of death in developed and developing societies and aging is the primary risk factor for CVD. Much of the increased risk of CVD in midlife/older adults (i.e., adults aged 50 years and older) is due to ...

Abstract	Cardiovascular diseases (CVD) remain the leading cause of death in developed and developing societies and aging is the primary risk factor for CVD. Much of the increased risk of CVD in midlife/older adults (i.e., adults aged 50 years and older) is due to increases in blood pressure, vascular endothelial dysfunction and stiffening of the large elastic arteries. Aerobic exercise training is an effective lifestyle intervention to improve CV function and decrease CVD risk with aging. However, <40% of midlife/older adults meet guidelines for aerobic exercise, due to time availability-related barriers and other obstacles to adherence. Therefore, there is a need for new lifestyle interventions that not only improve CV function with aging but also promote adherence. High-resistance inspiratory muscle strength training (IMST) is an emerging, time-efficient (5 min/day) lifestyle intervention. Early research suggests high-resistance IMST may promote adherence, lower blood pressure and potentially improve vascular endothelial function. However, additional investigation will be required to more definitively establish high-resistance IMST as a healthy lifestyle intervention for CV aging. This review will summarize the current evidence on high-resistance IMST for improving CV function with aging and will identify key research gaps and future directions.
MeSH term(s)	Aged ; Aging ; Arteries ; Blood Pressure ; Humans ; Middle Aged ; Muscle Strength ; Muscles ; Resistance Training
Language	English
Publishing date	2021-08-10
Publishing country	England
Document type	Journal Article ; Research Support, N.I.H., Extramural ; Review
ZDB-ID	390992-x
ISSN	1873-6815 ; 0531-5565
ISSN (online)	1873-6815
ISSN	0531-5565
DOI	10.1016/j.exger.2021.111515
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