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  1. Article: Timeline of FDA-Approved Targeted Therapy for Cholangiocarcinoma.

    Cho, Su Min / Esmail, Abdullah / Raza, Ali / Dacha, Sunil / Abdelrahim, Maen

    Cancers

    2022  Volume 14, Issue 11

    Abstract: Cholangiocarcinoma (CCA) represents approximately 3% of gastrointestinal malignancies worldwide and constitutes around 10-15% of all primary liver cancers, being only second to hepatocellular carcinoma. Mortality from CCA has been on the rise in recent ... ...

    Abstract Cholangiocarcinoma (CCA) represents approximately 3% of gastrointestinal malignancies worldwide and constitutes around 10-15% of all primary liver cancers, being only second to hepatocellular carcinoma. Mortality from CCA has been on the rise in recent decades, and in the United States alone there has been a 36% increase in CCA from 1999 to 2014, with over 7000 CCA mortalities since 2013. Targeted therapies, which have been gaining interest due to their greater specificity toward cancer cells, have only recently started gaining FDA approval for the treatment of CCA. In this manuscript, we will go through the timeline of current FDA-approved targeted therapies as well as those that have gained FDA breakthrough therapy designation.
    Language English
    Publishing date 2022-05-26
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2527080-1
    ISSN 2072-6694
    ISSN 2072-6694
    DOI 10.3390/cancers14112641
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  2. Article ; Online: Core curriculum for endoscopic submucosal dissection (ESD).

    Aihara, Hiroyuki / Dacha, Sunil / Anand, Gobind S / Byrne, Kathryn R / Chahal, Prabhleen / James, Theodore / Kowalski, Thomas E / Repaka, Aparna / Saadi, Mohammed / Sheth, Sunil G / Taylor, Jason R / Williams, Renee L / Wagh, Mihir S

    Gastrointestinal endoscopy

    2021  Volume 93, Issue 6, Page(s) 1215–1221

    Language English
    Publishing date 2021-04-02
    Publishing country United States
    Document type Practice Guideline
    ZDB-ID 391583-9
    ISSN 1097-6779 ; 0016-5107
    ISSN (online) 1097-6779
    ISSN 0016-5107
    DOI 10.1016/j.gie.2021.01.026
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  3. Article ; Online: Choledochocolonic Fistula as the Cause for Chronic Diarrhea.

    Dacha, Sunil / Dwadasi, Sujaata / Keilin, Steven

    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association

    2016  Volume 15, Issue 1, Page(s) A49

    MeSH term(s) Cholangiopancreatography, Endoscopic Retrograde ; Chronic Disease ; Colonic Diseases/complications ; Colonic Diseases/diagnostic imaging ; Common Bile Duct Diseases/complications ; Common Bile Duct Diseases/diagnostic imaging ; Diarrhea/etiology ; Humans ; Intestinal Fistula/complications ; Intestinal Fistula/diagnostic imaging ; Male ; Middle Aged
    Language English
    Publishing date 2016-09-06
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 2119789-1
    ISSN 1542-7714 ; 1542-3565
    ISSN (online) 1542-7714
    ISSN 1542-3565
    DOI 10.1016/j.cgh.2016.08.040
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  4. Article ; Online: Core curriculum for ergonomics in endoscopy.

    Walsh, Catharine M / Qayed, Emad / Aihara, Hiroyuki / Anand, Gobind S / Byrne, Kathryn / Chahal, Prabhleen / Dacha, Sunil / James, Theodore W / Kowalski, Thomas E / Repaka, Aparna / Saadi, Mohammed / Sheth, Sunil G / Taylor, Jason R / Williams, Renee L / Wagh, Mihir S

    Gastrointestinal endoscopy

    2021  Volume 93, Issue 6, Page(s) 1222–1227

    Language English
    Publishing date 2021-04-02
    Publishing country United States
    Document type Practice Guideline
    ZDB-ID 391583-9
    ISSN 1097-6779 ; 0016-5107
    ISSN (online) 1097-6779
    ISSN 0016-5107
    DOI 10.1016/j.gie.2021.01.023
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  5. Article ; Online: Core curriculum for peroral endoscopic myotomy (POEM).

    Dacha, Sunil / Aihara, Hiroyuki / Anand, Gobind S / Byrne, Kathryn R / Chahal, Prabhleen / James, Theodore / Kowalski, Thomas E / Qayed, Emad / Repaka, Aparna / Saadi, Mohammed / Sheth, Sunil G / Taylor, Jason R / Walsh, Catharine M / Williams, Renee L / Wagh, Mihir S

    Gastrointestinal endoscopy

    2021  Volume 93, Issue 3, Page(s) 539–543

    MeSH term(s) Curriculum ; Esophageal Achalasia/surgery ; Heller Myotomy ; Humans ; Myotomy ; Natural Orifice Endoscopic Surgery ; Treatment Outcome
    Language English
    Publishing date 2021-01-07
    Publishing country United States
    Document type Practice Guideline
    ZDB-ID 391583-9
    ISSN 1097-6779 ; 0016-5107
    ISSN (online) 1097-6779
    ISSN 0016-5107
    DOI 10.1016/j.gie.2020.10.026
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  6. Article ; Online: Advanced endoscopy fellowship training in the United States: recent trends in American Society for Gastrointestinal Endoscopy advanced endoscopy fellowship match, trainee experience, and postfellowship employment.

    Qayed, Emad / Sheth, Sunil G / Aihara, Hiroyuki / Anand, Gobind S / Byrne, Kathryn R / Chahal, Prabhleen / Dacha, Sunil / James, Theodore / Kowalski, Thomas E / Repaka, Aparna / Saadi, Mohammed / Taylor, Jason R / Williams, Renee L / Wagh, Mihir S

    Gastrointestinal endoscopy

    2021  Volume 93, Issue 6, Page(s) 1207–1214.e2

    Abstract: Background and aims: The American Society for Gastrointestinal Endoscopy (ASGE) advanced endoscopy fellowship (AEF) match offers a structured application process for AEF training in the United States. Our aim was to describe recent trends in AEF match, ... ...

    Abstract Background and aims: The American Society for Gastrointestinal Endoscopy (ASGE) advanced endoscopy fellowship (AEF) match offers a structured application process for AEF training in the United States. Our aim was to describe recent trends in AEF match, trainee experience, and postfellowship employment.
    Methods: ASGE AEF match data from 2012 to 2020 were reviewed. Online surveys were sent to advanced endoscopy trainees in 2019 and 2020 to explore their perceptions about AEF training and postfellowship jobs.
    Results: Data for 2020 showed 19% of matched applicants were women, 55% foreign medical graduates, and 17.5% U.S. visa holders. The number of AEF match applicants increased by 15.6% (90 in 2012 to 104 in 2020) and number of AEF programs increased by 23.5% (51 in 2012 to 63 in 2020). The average applicant match rate was 57% (range, 52.8%-60.6%) and position match rate 87.9% (range, 79.1%-94.6%). Ninety-one percent of trainees (n = 58) rated the quality of their training as very good/excellent; 75% of trainees participated in >300 ERCPs and 64.1% in >300 EUS cases. Seventy percent of trainees reported that advanced endoscopic procedures comprised ≤50% of their procedure volume in their first job, and 71.9% believed it was not easy to find a job after fellowship; however, 97% believed they would make the same decision to pursue AEF training again.
    Conclusions: There has been a steady increase in the number of advanced endoscopy applicants and training positions over recent years. Most graduating fellows reported 50% or less of their upcoming clinical practice would involve advanced endoscopic procedures. Future studies are needed to further clarify employment opportunities and personnel needs for advanced endoscopists.
    MeSH term(s) Education, Medical, Graduate ; Employment ; Endoscopy, Gastrointestinal ; Fellowships and Scholarships ; Female ; Humans ; Internship and Residency ; Male ; United States
    Language English
    Publishing date 2021-04-05
    Publishing country United States
    Document type Practice Guideline ; Journal Article
    ZDB-ID 391583-9
    ISSN 1097-6779 ; 0016-5107
    ISSN (online) 1097-6779
    ISSN 0016-5107
    DOI 10.1016/j.gie.2021.01.027
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  7. Article ; Online: Esophageal Strictures: An Unusual Presentation of a Common Disorder.

    Shroff, Sagar R / Dacha, Sunil / Iskandar, Heba

    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association

    2015  Volume 13, Issue 10, Page(s) A19–20

    MeSH term(s) Esophageal Stenosis/etiology ; Esophageal Stenosis/pathology ; Esophagoscopy ; Esophagus/diagnostic imaging ; Esophagus/pathology ; Female ; Histocytochemistry ; Humans ; Microscopy ; Middle Aged ; Radiography ; Sarcoidosis/complications ; Sarcoidosis/diagnosis
    Language English
    Publishing date 2015-10
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 2119789-1
    ISSN 1542-7714 ; 1542-3565
    ISSN (online) 1542-7714
    ISSN 1542-3565
    DOI 10.1016/j.cgh.2015.05.033
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  8. Article: A Case of an Ectopic Ampulla of Vater in the Pyloric Channel.

    Dacha, Sunil / Wang, Xiao Jing / Qayed, Emad

    ACG case reports journal

    2014  Volume 1, Issue 3, Page(s) 161–163

    Abstract: A 51-year-old male presented with abdominal pain and jaundice. He was subsequently diagnosed with cholestatic jaundice and cholangitis. A side-viewing duodenoscope failed to identify the ampulla of Vater in the second portion of duodenum. A regular ... ...

    Abstract A 51-year-old male presented with abdominal pain and jaundice. He was subsequently diagnosed with cholestatic jaundice and cholangitis. A side-viewing duodenoscope failed to identify the ampulla of Vater in the second portion of duodenum. A regular gastroscope was used, and an ectopic ampulla of Vater was identified in the pyloric channel.
    Language English
    Publishing date 2014-04-04
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2814825-3
    ISSN 2326-3253
    ISSN 2326-3253
    DOI 10.14309/crj.2014.37
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  9. Article ; Online: Microsporidiosis: an unusual endoscopic finding.

    Dacha, Sunil / Pham, Donald / Cai, Qiang

    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association

    2014  Volume 12, Issue 5, Page(s) e37–8

    MeSH term(s) Aged ; Endoscopy, Gastrointestinal ; Gastrointestinal Diseases/diagnosis ; Gastrointestinal Diseases/pathology ; Histocytochemistry ; Humans ; Macrophages/microbiology ; Macrophages/pathology ; Male ; Microscopy ; Microsporidiosis/diagnosis ; Microsporidiosis/pathology ; Mucous Membrane/microbiology ; Mucous Membrane/pathology
    Language English
    Publishing date 2014-05
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 2119789-1
    ISSN 1542-7714 ; 1542-3565
    ISSN (online) 1542-7714
    ISSN 1542-3565
    DOI 10.1016/j.cgh.2013.08.030
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Hypergastrinemia.

    Dacha, Sunil / Razvi, Mohammed / Massaad, Julia / Cai, Qiang / Wehbi, Mohammad

    Gastroenterology report

    2015  Volume 3, Issue 3, Page(s) 201–208

    Abstract: Gastrin is an important hormone of the digestive system, which assists gastric acid secretion. It may be pathologically elevated in conditions such as Zollinger-Ellison syndrome, or due to common medications such as proton pump inhibitors. In this review ...

    Abstract Gastrin is an important hormone of the digestive system, which assists gastric acid secretion. It may be pathologically elevated in conditions such as Zollinger-Ellison syndrome, or due to common medications such as proton pump inhibitors. In this review we provide an overview of the pathophysiology and medical causes of hypergastrinemia, diagnostic testing and clinical consequences of chronic hypergastrinemia.
    Language English
    Publishing date 2015-02-18
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2710871-5
    ISSN 2052-0034
    ISSN 2052-0034
    DOI 10.1093/gastro/gov004
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