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  1. Article ; Online: Fetal biomarkers for lower urinary tract obstruction secondary to posterior urethral valves.

    Schanstra, Joost P / Decramer, Stéphane / Buffin-Meyer, Bénédicte / Klein, Julie / Fossum, Magdalena / Wu, Hsi-Yang

    Journal of pediatric urology

    2024  

    Abstract: Today, prenatal diagnosis of congenital urogenital malformations is mostly dependent on anatomical variations found on imaging. However, these findings can mislead us in telling us when to intervene, and about post-natal prognosis. Since many findings ... ...

    Abstract Today, prenatal diagnosis of congenital urogenital malformations is mostly dependent on anatomical variations found on imaging. However, these findings can mislead us in telling us when to intervene, and about post-natal prognosis. Since many findings are dependent on multiple assessments, delayed diagnosis can occur, leading to less optimal outcomes compared to early intervention. Analyses of fetal urinary biomarkers have been proposed as a method of finding biological changes that are predictive for diagnosis and prognosis in fetuses at risk of kidney disease. We interviewed a group of researchers that have demonstrated that by combining multiple omics traits extracted from fetal urine, the biological variability found in single omics data can be circumvented. By analyzing multiple fetal urine peptides and metabolites at single time point, the prognostic power of postnatal renal outcome in fetuses with lower urinary tract obstruction is significantly increased. In this interview, we inquired about the technical aspects of the tests, challenges, and limitations the research group have come across, and how they envision the future for multi-omics fetal analysis in the clinic.
    Language English
    Publishing date 2024-01-14
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2237683-5
    ISSN 1873-4898 ; 1477-5131
    ISSN (online) 1873-4898
    ISSN 1477-5131
    DOI 10.1016/j.jpurol.2024.01.011
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6387: Show issues Location:
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  2. Article: Reducing Red Tape's Negative Consequences for Leaders: The Buffering Role of Autonomous Motivation.

    Muylaert, Jolien / Bauwens, Robin / Audenaert, Mieke / Decramer, Adelien

    Frontiers in psychology

    2022  Volume 12, Page(s) 806388

    Abstract: In a context where the amount of red tape in healthcare organizations continues to rise, head nurses' job satisfaction is constantly under pressure. By building on the Job Demands-Resources model, we developed a theoretical model investigating the ... ...

    Abstract In a context where the amount of red tape in healthcare organizations continues to rise, head nurses' job satisfaction is constantly under pressure. By building on the Job Demands-Resources model, we developed a theoretical model investigating the relationship between red tape and job satisfaction. By investigating the mediating role of discretionary room and the moderating role of autonomous motivation in this relationship, this study does not only aim to provide additional knowledge regarding the underlying mechanisms in this relationship, but also to increase our understanding of how this suffering at work can be mitigated. Our conditional process analyses (
    Language English
    Publishing date 2022-01-14
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2563826-9
    ISSN 1664-1078
    ISSN 1664-1078
    DOI 10.3389/fpsyg.2021.806388
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  3. Article ; Online: How to foster employee quality of life: The role of employee performance management and authentic leadership.

    Audenaert, Mieke / Decramer, Adelien / George, Bert

    Evaluation and program planning

    2021  Volume 85, Page(s) 101909

    Abstract: Although employee performance management (EPM) enhances performance, the effects that these systems have on employee quality of life remain unclear. Such information is particularly relevant for 'vulnerable' workers, whose employment situation has the ... ...

    Abstract Although employee performance management (EPM) enhances performance, the effects that these systems have on employee quality of life remain unclear. Such information is particularly relevant for 'vulnerable' workers, whose employment situation has the potential to alter their social and economic position in life. Based on data gathered from 111 leaders and 547 vulnerable workers in 36 social profit organizations, multilevel regression analysis demonstrates that EPM is related to vulnerable workers' quality of life. Moreover, authentic leadership and psychological empowerment buffer the negative relationship between EPM and vulnerable workers' quality of life. These findings imply that organizations that employ vulnerable workers need authentic leaders to foster a positive impact not only on performance through EPM but also on vulnerable workers' quality of life. In addition, organizations can also pursue vulnerable workers' psychological empowerment by providing tasks that are meaningful to them and in which they experience self-efficacy to reduce the potential negative effects of EPM on vulnerable workers' quality of life.
    MeSH term(s) Employment ; Humans ; Leadership ; Organizations ; Program Evaluation ; Quality of Life
    Language English
    Publishing date 2021-02-04
    Publishing country England
    Document type Journal Article
    ZDB-ID 2013444-7
    ISSN 1873-7870 ; 0149-7189
    ISSN (online) 1873-7870
    ISSN 0149-7189
    DOI 10.1016/j.evalprogplan.2021.101909
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  4. Article ; Online: The European respiratory roadmap.

    Decramer, Marc

    Multidisciplinary respiratory medicine

    2011  Volume 6, Issue 5, Page(s) 272–273

    Language English
    Publishing date 2011-10-31
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 2677839-7
    ISSN 2049-6958 ; 2049-6958
    ISSN (online) 2049-6958
    ISSN 2049-6958
    DOI 10.1186/2049-6958-6-5-272
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  5. Article ; Online: The European respiratory roadmap.

    Decramer, Marc

    Lancet (London, England)

    2011  Volume 378, Issue 9805, Page(s) 1765–1767

    MeSH term(s) Asthma/epidemiology ; Asthma/prevention & control ; Asthma/therapy ; Europe/epidemiology ; European Union ; Humans ; Pulmonary Disease, Chronic Obstructive/epidemiology ; Pulmonary Disease, Chronic Obstructive/prevention & control ; Pulmonary Disease, Chronic Obstructive/therapy ; Pulmonary Medicine/manpower ; Research Support as Topic ; Risk Factors ; Smoking/epidemiology ; Smoking Prevention
    Language English
    Publishing date 2011-11-19
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 3306-6
    ISSN 1474-547X ; 0023-7507 ; 0140-6736
    ISSN (online) 1474-547X
    ISSN 0023-7507 ; 0140-6736
    DOI 10.1016/S0140-6736(11)60619-3
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    In stock of ZB MED Cologne/Königswinter

    Ua VI Zs.5: Show issues Location:
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    Zs.MG 94: Show issues

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  6. Book ; Thesis: Respiratory muscle mechanics in dogs

    Decramer, Marc

    an experimental study

    1986  

    Size 206 S. : graph. Darst.
    Publishing country Belgium
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Leuven, Kathol. Univ., Diss., 1986
    HBZ-ID HT003128261
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    88 E 1635 order for loan Magazin

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  7. Article ; Online: Who can pay for innovative medicines?

    Decramer, Stefaan / Decramer, Marc

    The European respiratory journal

    2013  Volume 41, Issue 3, Page(s) 495–496

    MeSH term(s) Biomedical Research ; Drug Discovery/economics ; Drug Industry ; Drug Therapy/economics ; Economics, Pharmaceutical ; Europe ; Financing, Government ; Humans ; Respiratory Tract Diseases/drug therapy ; Respiratory Tract Diseases/economics ; United States
    Language English
    Publishing date 2013-03
    Publishing country England
    Document type Editorial
    ZDB-ID 639359-7
    ISSN 1399-3003 ; 0903-1936
    ISSN (online) 1399-3003
    ISSN 0903-1936
    DOI 10.1183/09031936.00135412
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    Zs.A 2322: Show issues Location:
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    Zs.MO 292: Show issues

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  8. Article ; Online: Pediatric urogenital schistosomiasis diagnosed in France.

    Percheron, Lucas / Leblanc, Claire / Ulinski, Tim / Fila, Marc / Malvy, Denis / Bacchetta, Justine / Guigonis, Vincent / Debuisson, Cecile / Launay, Elise / Martinez, Edouard / Morand, Aurelie / Decramer, Stéphane / Schanstra, Joost-Peter / Berry, Antoine

    Pediatric nephrology (Berlin, Germany)

    2024  Volume 39, Issue 6, Page(s) 1893–1900

    Abstract: ... centers were included. The median age was 14 years and the sex ratio M/F was 4:1. Hematuria was present ...

    Abstract Background: Schistosomiasis affects approximately 230 million people worldwide. There is an increased incidence of schistosomiasis cases in France acquired from outside the country. This increases the risk of schistosomiasis outbreaks as observed in Corsica. Clinicians from non-endemic regions are not accustomed to diagnosing and managing this pathology. The objective of this study is to provide a better description of the clinical and paraclinical characteristics and disease evolution of affected children.
    Methods: Through the French Pediatric Nephrology Society and the Pediatric Infectious Pathology Group, we contacted all French pediatric centers that may have treated children with urinary schistosomiasis between 2013 and 2019. Age, sex, comorbidities, and clinical, biological, and radiological data (at discovery and follow-up) were collected retrospectively.
    Results: A total of 122 patients from 10 different centers were included. The median age was 14 years and the sex ratio M/F was 4:1. Hematuria was present in 82% of the patients while urinary tract abnormality was found in 36% of them. Fourteen patients (11%) displayed complicated forms of urinary schistosomiasis including 10 patients with chronic kidney disease. A total of 110 patients received treatment with praziquantel, which was well-tolerated and led to clinical resolution of symptoms in 98% of cases.
    Conclusion: Patients with schistosomiasis present frequent kidney, urinary, or genital involvement. Systematic screening of patients returning from endemic areas is therefore recommended, especially since treatment with antiparasitic drugs is effective and well-tolerated. Enhancing medical knowledge of this pathology among all practitioners is essential to improve care and outcomes.
    MeSH term(s) Humans ; Child ; Adolescent ; Animals ; Schistosomiasis haematobia/diagnosis ; Schistosomiasis haematobia/drug therapy ; Schistosomiasis haematobia/epidemiology ; Retrospective Studies ; Praziquantel/therapeutic use ; Hematuria ; France/epidemiology ; Schistosoma haematobium
    Chemical Substances Praziquantel (6490C9U457)
    Language English
    Publishing date 2024-01-12
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 631932-4
    ISSN 1432-198X ; 0931-041X
    ISSN (online) 1432-198X
    ISSN 0931-041X
    DOI 10.1007/s00467-023-06260-x
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    Zs.A 2196: Show issues Location:
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  9. Article: Description of Trichodorus marylandi n. sp. (Nematoda: Trichodoridae) from Maryland, USA

    Decramer, W. / Kantor, M. R. / Handoo, Z. A. / Subbotin, S. A.

    Nematology

    2022  Volume 24, Issue 3, Page(s) 307

    Language English
    Document type Article
    ZDB-ID 1450013-9
    ISSN 1388-5545
    Database Current Contents Nutrition, Environment, Agriculture

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    In stock of ZB MED Bonn / Germany

    Z 7171: Show issues

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  10. Article: Response of the respiratory muscles to rehabilitation in COPD.

    Decramer, Marc

    Journal of applied physiology (Bethesda, Md. : 1985)

    2009  Volume 107, Issue 3, Page(s) 971–976

    Abstract: Respiratory rehabilitation is known to improve outcomes in patients with chronic obstructive pulmonary disease (COPD). The question addressed in the present review is whether these beneficial effects are related to improvements in inspiratory muscle ... ...

    Abstract Respiratory rehabilitation is known to improve outcomes in patients with chronic obstructive pulmonary disease (COPD). The question addressed in the present review is whether these beneficial effects are related to improvements in inspiratory muscle function. Respiratory muscle fatigue often did not occur during exercise in patients with COPD, since exercise limitation usually occurred when significant force reserve in the inspiratory muscles was still present. Notwithstanding, a number of observations may provide indirect evidence that respiratory muscle fatigue may occur during exercise. Some evidence is present that, in normal humans, whole body exercise training improved inspiratory muscle endurance, but no studies are available in patients with COPD. Animal studies invariably demonstrated that exercise training increased the number of oxidative fibers and oxidative enzyme activity in inspiratory muscles. These effects, however, were considerably smaller than the effects found on peripheral muscles with similar fiber composition. Clear evidence indicated that inspiratory muscle training (IMT) improved inspiratory muscle function. Two large meta-analyses indicated that, if the training load was properly controlled, IMT alone or combined with general exercise reconditioning improved inspiratory muscle strength and endurance and dyspnea. The combination did not result in greater improvements in functional exercise capacity. Animal studies and one patient study confirmed the occurrence of structural remodeling of the inspiratory muscles in response to IMT. The final question is whether improvements in inspiratory muscle function produced by IMT lead to improved outcomes in COPD. In all five studies in which training load was adequately controlled, a significant reduction of dyspnea during activities of daily living was found. Eight randomized studies examined the effects of the combination. Greater improvements in exercise capacity were only found in three studies, and none showed a greater reduction in dyspnea.
    MeSH term(s) Exercise/physiology ; Humans ; Muscle Fatigue/physiology ; Physical Fitness/physiology ; Pulmonary Disease, Chronic Obstructive/physiopathology ; Pulmonary Disease, Chronic Obstructive/rehabilitation ; Respiratory Muscles/physiopathology
    Language English
    Publishing date 2009-09
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 219139-8
    ISSN 1522-1601 ; 8750-7587 ; 0021-8987 ; 0161-7567
    ISSN (online) 1522-1601
    ISSN 8750-7587 ; 0021-8987 ; 0161-7567
    DOI 10.1152/japplphysiol.91459.2008
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