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  1. Article ; Online: Is hyperoxaemia a risk factor for ICU-acquired pneumonia?

    Jaffal, Karim / Six, Sophie / Zerimech, Farid / Nseir, Saad

    The Lancet. Respiratory medicine

    2017  Volume 5, Issue 5, Page(s) e16

    Language English
    Publishing date 2017-05
    Publishing country England
    Document type Letter
    ZDB-ID 2686754-0
    ISSN 2213-2619 ; 2213-2600
    ISSN (online) 2213-2619
    ISSN 2213-2600
    DOI 10.1016/S2213-2600(17)30121-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Countrywide multi-serotype outbreak of

    Pardos de la Gandara, Maria / Fournet, Nelly / Bonifait, Laetitia / Lefèvre, Sophie / Chemaly, Marianne / Grastilleur, Charlotte / Cadel-Six, Sabrina / Fach, Patrick / Pignault, Agnès / Brisabois, Anne / Jourdan-Da Silva, Nathalie / Weill, François-Xavier

    Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin

    2023  Volume 28, Issue 2

    Abstract: The French National Reference Centre ... ...

    Abstract The French National Reference Centre for
    MeSH term(s) Animals ; Female ; Male ; Humans ; Swine ; Child ; Salmonella typhimurium/genetics ; Serogroup ; Salmonella Food Poisoning/epidemiology ; Salmonella Food Poisoning/microbiology ; Meat Products ; Red Meat/microbiology ; Pork Meat ; France/epidemiology ; Disease Outbreaks
    Language English
    Publishing date 2023-01-25
    Publishing country Sweden
    Document type Journal Article
    ZDB-ID 1338803-4
    ISSN 1560-7917 ; 1025-496X
    ISSN (online) 1560-7917
    ISSN 1025-496X
    DOI 10.2807/1560-7917.ES.2023.28.2.2200123
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Controls on timescales of soil organic carbon persistence across sub-Saharan Africa.

    von Fromm, Sophie F / Doetterl, Sebastian / Butler, Benjamin M / Aynekulu, Ermias / Berhe, Asmeret Asefaw / Haefele, Stephan M / McGrath, Steve P / Shepherd, Keith D / Six, Johan / Tamene, Lulseged / Tondoh, Ebagnerin J / Vågen, Tor-Gunnar / Winowiecki, Leigh A / Trumbore, Susan E / Hoyt, Alison M

    Global change biology

    2024  Volume 30, Issue 1, Page(s) e17089

    Abstract: Given the importance of soil for the global carbon cycle, it is essential to understand not only how much carbon soil stores but also how long this carbon persists. Previous studies have shown that the amount and age of soil carbon are strongly affected ... ...

    Abstract Given the importance of soil for the global carbon cycle, it is essential to understand not only how much carbon soil stores but also how long this carbon persists. Previous studies have shown that the amount and age of soil carbon are strongly affected by the interaction of climate, vegetation, and mineralogy. However, these findings are primarily based on studies from temperate regions and from fine-scale studies, leaving large knowledge gaps for soils from understudied regions such as sub-Saharan Africa. In addition, there is a lack of data to validate modeled soil C dynamics at broad scales. Here, we present insights into organic carbon cycling, based on a new broad-scale radiocarbon and mineral dataset for sub-Saharan Africa. We found that in moderately weathered soils in seasonal climate zones with poorly crystalline and reactive clay minerals, organic carbon persists longer on average (topsoil: 201 ± 130 years; subsoil: 645 ± 385 years) than in highly weathered soils in humid regions (topsoil: 140 ± 46 years; subsoil: 454 ± 247 years) with less reactive minerals. Soils in arid climate zones (topsoil: 396 ± 339 years; subsoil: 963 ± 669 years) store organic carbon for periods more similar to those in seasonal climate zones, likely reflecting climatic constraints on weathering, carbon inputs and microbial decomposition. These insights into the timescales of organic carbon persistence in soils of sub-Saharan Africa suggest that a process-oriented grouping of soils based on pedo-climatic conditions may be useful to improve predictions of soil responses to climate change at broader scales.
    MeSH term(s) Soil/chemistry ; Carbon ; Minerals ; Carbon Sequestration ; Africa South of the Sahara
    Chemical Substances Soil ; Carbon (7440-44-0) ; Minerals
    Language English
    Publishing date 2024-01-25
    Publishing country England
    Document type Journal Article
    ZDB-ID 1281439-8
    ISSN 1365-2486 ; 1354-1013
    ISSN (online) 1365-2486
    ISSN 1354-1013
    DOI 10.1111/gcb.17089
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  4. Article: Source Attribution Study of Sporadic

    Sévellec, Yann / Granier, Sophie A / Le Hello, Simon / Weill, François-Xavier / Guillier, Laurent / Mistou, Michel-Yves / Cadel-Six, Sabrina

    Frontiers in microbiology

    2020  Volume 11, Page(s) 889

    Abstract: Salmonella ... ...

    Abstract Salmonella enterica
    Language English
    Publishing date 2020-05-14
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587354-4
    ISSN 1664-302X
    ISSN 1664-302X
    DOI 10.3389/fmicb.2020.00889
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  5. Article: Accuracy of ventilator-associated events for the diagnosis of ventilator-associated lower respiratory tract infections.

    Pouly, Olivier / Lecailtel, Sylvain / Six, Sophie / Préau, Sébastien / Wallet, Frédéric / Nseir, Saad / Rouzé, Anahita

    Annals of intensive care

    2020  Volume 10, Issue 1, Page(s) 6

    Abstract: Background: The aim of this study was to investigate the concordance between ventilator-associated events (VAE) and ventilator-associated lower respiratory tract infections (VA-LRTI), and their impact on outcome.: Methods: This retrospective study ... ...

    Abstract Background: The aim of this study was to investigate the concordance between ventilator-associated events (VAE) and ventilator-associated lower respiratory tract infections (VA-LRTI), and their impact on outcome.
    Methods: This retrospective study was performed in five 10-bed ICUs of a teaching hospital, during a 2-year period. Ventilator-associated lower respiratory tract infections (VA-LRTI), including ventilator-associated tracheobronchitis (VAT) and ventilator-associated pneumonia (VAP) were prospectively diagnosed. The agreement between VAE, VAT and VAP was assessed by k statistics.
    Results: A total of 1059 patients (15,029 ventilator-days) were included. 268 VAP (17.8 per 1000 ventilator-days), 127 VAT (8.5 per 1000 ventilator-days) and 262 VAE (17.4 per 1000 ventilator-days) were diagnosed. There was no agreement between VAT and VAE, and the agreement was poor between VAP and VAE (k = 0.12, 95% CI 0.03-0.20). VAE and VA-LRTI were associated with significantly longer duration of mechanical ventilation, ICU and hospital length of stay. VAP, VAT and VAE were not significantly associated with mortality in multivariate analysis.
    Conclusions: The agreement was poor between VAE and VAP. No agreement was found between VAE and VAT. VAE episodes were significantly associated with longer duration of mechanical ventilation and length of stay, but not with ICU mortality.
    Keywords covid19
    Language English
    Publishing date 2020-01-13
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2617094-2
    ISSN 2110-5820
    ISSN 2110-5820
    DOI 10.1186/s13613-020-0624-6
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  6. Article: Relationship between hyperoxemia and ventilator associated pneumonia.

    Jaffal, Karim / Six, Sophie / Zerimech, Farid / Nseir, Saad

    Annals of translational medicine

    2017  Volume 5, Issue 22, Page(s) 453

    Abstract: Previous studies suggest a relationship between hyperoxemia and ventilator-associated pneumonia (VAP). Hyperoxemia is responsible for denitrogenation phenomena, and inhibition of surfactant production, promoting atelectasis in mechanically ventilated ... ...

    Abstract Previous studies suggest a relationship between hyperoxemia and ventilator-associated pneumonia (VAP). Hyperoxemia is responsible for denitrogenation phenomena, and inhibition of surfactant production, promoting atelectasis in mechanically ventilated patients. Further, hyperoxemia impairs the efficacy of alveolar macrophages to migrate, phagocyte and kill bacteria. Oxygen can also cause pulmonary-specific toxic effect called hyperoxic acute lung injury leading to longer duration of mechanical ventilation. All these hyperoxic effects are well-known risk factors for VAP. A recent retrospective large single center study identified hyperoxemia as an independent risk factor for VAP. However, two recent randomized controlled trials evaluated the impact of conservative oxygen strategy versus a liberal strategy, but did not confirm the role of hyperoxemia in lower respiratory tract infection occurrence. In this review, we discuss animal and human studies suggesting a relationship between these two common conditions in mechanically ventilated patients and potential interventions that should be evaluated. Further large prospective studies in carefully selected groups of patients are required to confirm the potential role of hyperoxemia in VAP pathogenesis and to evaluate the impact of a conservative oxygen strategy
    Language English
    Publishing date 2017-09-18
    Publishing country China
    Document type Journal Article ; Review
    ZDB-ID 2893931-1
    ISSN 2305-5847 ; 2305-5839
    ISSN (online) 2305-5847
    ISSN 2305-5839
    DOI 10.21037/atm.2017.10.15
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  7. Article ; Online: Nutrition as a driver and outcome of agroecology.

    van Zutphen, Kesso Gabrielle / van den Berg, Sophie / Gavin-Smith, Breda / Imbo, Elizabeth / Kraemer, Klaus / Monroy-Gomez, Jimena / Pannatier, Marnie / Prytherch, Helen / Six, Johan / Thoennissen, Carmen / Winter, Simon / Barjolle, Dominique

    Nature food

    2022  Volume 3, Issue 12, Page(s) 990–996

    Abstract: The principles of agroecology do not explicitly state a link with nutrition. Yet, we argue that among them, input reduction, biodiversity, economic diversification, social values and diets, fairness, connectivity and participation are directly linked to ... ...

    Abstract The principles of agroecology do not explicitly state a link with nutrition. Yet, we argue that among them, input reduction, biodiversity, economic diversification, social values and diets, fairness, connectivity and participation are directly linked to nutrition. Nutrition can serve as a critical outcome and driver of agroecological practices and can drive transformative change across the food system.
    Language English
    Publishing date 2022-12-05
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ISSN 2662-1355
    ISSN (online) 2662-1355
    DOI 10.1038/s43016-022-00631-7
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  8. Article ; Online: Physiology of maerl algae: Comparison of inter- and intraspecies variations.

    Qui-Minet, Zujaila Nohemy / Davoult, Dominique / Grall, Jacques / Delaunay, Coralie / Six, Christophe / Cariou, Thierry / Martin, Sophie

    Journal of phycology

    2021  Volume 57, Issue 3, Page(s) 831–848

    Abstract: Free-living red coralline algae play an important role in the carbon and carbonate cycles of coastal environments. In this study, we examined the physiology of free-living coralline algae-forming maerl beds in the Bay of Brest (Brittany, France), where ... ...

    Abstract Free-living red coralline algae play an important role in the carbon and carbonate cycles of coastal environments. In this study, we examined the physiology of free-living coralline algae-forming maerl beds in the Bay of Brest (Brittany, France), where Lithothamnion corallioides is the dominant maerl (i.e., rhodolith) species. Phymatolithon calcareum and Lithophyllum incrustans are also present (in lower abundances) at a specific site in the bay. We aimed to assess how maerl physiology is affected by seasonality and/or local environmental variations at the inter- and intraspecific levels. Physiological measurements (respiration, photosynthetic, and calcification rates) were performed using incubation chambers in winter and summer to compare (1) the dominant maerl species at three sites and (2) three coexisting maerl species at one site. Comparison of the three coexisting maerl species suggests that L. corallioides is the best adapted to the current environmental conditions in the Bay of Brest, because this species is the most robust to dissolution in the dark in winter and has the highest calcification efficiency in the light. Comparisons of L. corallioides metabolic rates between stations showed that morphological variations within this species are the main factor affecting its photosynthetic and calcification rates. Environmental factors such as freshwater inputs also affect its calcification rates in the dark. In addition to interspecies variation in maerl physiology, there were intraspecific variations associated with direct (water physico-chemistry) or indirect (morphology) local environmental conditions. This study demonstrates the plasticity of maerl physiology in response to environmental changes, which is fundamental for maerl persistence.
    MeSH term(s) Carbonates ; France ; Photosynthesis ; Rhodophyta ; Seasons
    Chemical Substances Carbonates
    Language English
    Publishing date 2021-04-05
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 281226-5
    ISSN 1529-8817 ; 0022-3646
    ISSN (online) 1529-8817
    ISSN 0022-3646
    DOI 10.1111/jpy.13119
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  9. Article ; Online: Human Osteoblast-Conditioned Media Can Influence

    Lamret, Fabien / Varin-Simon, Jennifer / Six, Mélodie / Thoraval, Léa / Chevrier, Julie / Adam, Cloé / Guillaume, Christine / Velard, Frédéric / Gangloff, Sophie C / Reffuveille, Fany

    International journal of molecular sciences

    2022  Volume 23, Issue 22

    Abstract: Osteoblasts are bone-forming and highly active cells participating in bone homeostasis. In the case of osteomyelitis and more specifically prosthetic joint infections (PJI) for ... ...

    Abstract Osteoblasts are bone-forming and highly active cells participating in bone homeostasis. In the case of osteomyelitis and more specifically prosthetic joint infections (PJI) for which
    MeSH term(s) Humans ; Staphylococcus aureus ; Methicillin-Resistant Staphylococcus aureus ; Culture Media, Conditioned/pharmacology ; Tumor Necrosis Factor-alpha/pharmacology ; Anti-Bacterial Agents/pharmacology ; Staphylococcal Infections/microbiology ; Biofilms ; Osteoblasts
    Chemical Substances Culture Media, Conditioned ; Tumor Necrosis Factor-alpha ; Anti-Bacterial Agents
    Language English
    Publishing date 2022-11-19
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms232214393
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  10. Article: Genetic Diversity of

    Sévellec, Yann / Felten, Arnaud / Radomski, Nicolas / Granier, Sophie A / Le Hello, Simon / Petrovska, Liljana / Mistou, Michel-Yves / Cadel-Six, Sabrina

    Pathogens (Basel, Switzerland)

    2019  Volume 8, Issue 2

    Abstract: ... ...

    Abstract Salmonella
    Language English
    Publishing date 2019-04-04
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2695572-6
    ISSN 2076-0817
    ISSN 2076-0817
    DOI 10.3390/pathogens8020046
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