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Article ; Online: Hyperphosphatemia, a Cause of High Anion Gap Metabolic Acidosis: Report of a Case and Review of the Literature.

Sadjadi, Seyed Ali / Pi, Alexander

2017 Volume 18, Page(s) 463–466

Abstract: BACKGROUND Hyperphosphatemia is a common problem in patients with kidney failure. It is usually mild and rarely severe enough to cause metabolic acidosis on its own. Besides kidney failure, use of phosphate containing enemas, rhabdomyolysis, and tumor ... ...

Abstract	BACKGROUND Hyperphosphatemia is a common problem in patients with kidney failure. It is usually mild and rarely severe enough to cause metabolic acidosis on its own. Besides kidney failure, use of phosphate containing enemas, rhabdomyolysis, and tumor lysis syndrome are common causes of severe hyperphosphatemia. CASE REPORT A 74-year-old man with a history of diabetes mellitus type II, arterial hypertension, and end stage renal disease, who was on hemodialysis and who had undergone hemicolectomy for ischemic bowel disease, and had not eaten for several days, developed severe metabolic acidosis, with an anion gap (AG) of 31 meq/L, -uncorrected for serum albumin. At that time he had a high level of beta-hydroxybutyrate and severe hyperphosphatemia (16.5 mg/dL). Metabolic acidosis and hyperphosphatemia were corrected with hemodialysis, confirming the role of hyperphosphatemia in the development of high AG metabolic acidosis. CONCLUSIONS Although our patient had many reasons to develop high AG metabolic acidosis, hyperphosphatemia played a significant role in his acidosis. Severe hyperphosphatemia is rarely mentioned as a cause of high AG acidosis. It should be added to the long list of causes of this metabolic disorder. Physiological basis of acid base changes are discussed.
MeSH term(s)	Acidosis/etiology ; Aged ; Humans ; Hyperphosphatemia/complications ; Hyperphosphatemia/etiology ; Kidney Failure, Chronic/complications ; Male
Language	English
Publishing date	2017-04-28
Publishing country	United States
Document type	Case Reports ; Journal Article ; Review
ZDB-ID	2517183-5
ISSN	1941-5923 ; 1941-5923
ISSN (online)	1941-5923
ISSN	1941-5923
DOI	10.12659/ajcr.902862
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Stochastic portfolio optimization: A regret-based approach on volatility risk measures: An empirical evidence from The New York stock market.

Larni-Fooeik, AmirMohammad / Sadjadi, Seyed Jafar / Mohammadi, Emran

PloS one

2024 Volume 19, Issue 4, Page(s) e0299699

Abstract: Portfolio optimization involves finding the ideal combination of securities and shares to reduce risk and increase profit in an investment. To assess the impact of risk in portfolio optimization, we utilize a significant volatility risk measure series. ... ...

Abstract	Portfolio optimization involves finding the ideal combination of securities and shares to reduce risk and increase profit in an investment. To assess the impact of risk in portfolio optimization, we utilize a significant volatility risk measure series. Behavioral finance biases play a critical role in portfolio optimization and the efficient allocation of stocks. Regret, within the realm of behavioral finance, is the feeling of remorse that causes hesitation in making significant decisions and avoiding actions that could lead to poor investment choices. This behavior often leads investors to hold onto losing investments for extended periods, refusing to acknowledge mistakes and accept losses. Ironically, by evading regret, investors may miss out on potential opportunities. in this paper, our purpose is to compare investment scenarios in the decision-making process and calculate the amount of regret obtained in each scenario. To accomplish this, we consider volatility risk metrics and utilize stochastic optimization to identify the most suitable scenario that not only maximizes yield in the investment portfolio and minimizes risk, but also minimizes resulting regret. To convert each multi-objective model into a single objective, we employ the augmented epsilon constraint (AEC) method to establish the Pareto efficiency frontier. As a means of validating the solution of this method, we analyze data spanning 20, 50, and 100 weeks from 150 selected stocks in the New York market based on fundamental analysis. The results show that the selection of the mad risk measure in the time horizon of 100 weeks with a regret rate of 0.104 is the most appropriate research scenario. this article recommended that investors diversify their portfolios by investing in a variety of assets. This can help reduce risk and increase overall returns and improve financial literacy among investors.
Language	English
Publishing date	2024-04-22
Publishing country	United States
Document type	Journal Article
ZDB-ID	2267670-3
ISSN	1932-6203 ; 1932-6203
ISSN (online)	1932-6203
ISSN	1932-6203
DOI	10.1371/journal.pone.0299699
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Article ; Online: Acyclovir Neurotoxicity in a Peritoneal Dialysis Patient: Report of a Case and Review of the Pharmacokinetics of Acyclovir.

Sadjadi, Seyed-Ali / Regmi, Surakshya / Chau, Tony

The American journal of case reports

2018 Volume 19, Page(s) 1459–1462

Abstract: BACKGROUND The elderly population in the United States and the world is rapidly increasing. With aging, immunity and kidney function decrease, thus predisposing people to viral illnesses for which there is no effective prophylaxis. Herpes zoster afflicts ...

Abstract	BACKGROUND The elderly population in the United States and the world is rapidly increasing. With aging, immunity and kidney function decrease, thus predisposing people to viral illnesses for which there is no effective prophylaxis. Herpes zoster afflicts the elderly and other immunocompromised patients, like those with end-stage renal disease, transplant recipients, and cancer patients, causing significant morbidity and sometimes mortality. Treating herpes zoster becomes problematic when the regular pharmacokinetics of the antiviral drugs are disturbed. CASE REPORT An 83-year-old African American man with end-stage kidney disease (ESRD) and on chronic peritoneal dialysis (PD) developed herpes zoster, for which he received the manufacturer-recommended intravenous dose of acyclovir. Shortly after taking the medication, he developed confusion, disorientation, and visual hallucinations. He was switched from PD to hemodialysis (HD), with successful recovery. Examination of the cerebrospinal fluid for meningitis and imaging studies of the head were negative. Serum levels of acyclovir were elevated. CONCLUSIONS Even when the acyclovir dose is properly adjusted for kidney function based on the current manufacturer's recommendations, it can cause neurotoxicity. Here, we discuss the pharmacokinetics of acyclovir and make some recommendations with regard to dose adjustment in patients with ESRD.
MeSH term(s)	Acyclovir/adverse effects ; Acyclovir/pharmacokinetics ; Aged, 80 and over ; Antiviral Agents/adverse effects ; Antiviral Agents/pharmacokinetics ; Humans ; Kidney Failure, Chronic/therapy ; Male ; Neurotoxicity Syndromes/diagnosis ; Neurotoxicity Syndromes/etiology ; Peritoneal Dialysis
Chemical Substances	Antiviral Agents ; Acyclovir (X4HES1O11F)
Language	English
Publishing date	2018-12-09
Publishing country	United States
Document type	Case Reports ; Journal Article ; Review
ZDB-ID	2517183-5
ISSN	1941-5923 ; 1941-5923
ISSN (online)	1941-5923
ISSN	1941-5923
DOI	10.12659/AJCR.911520
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Article ; Online: Identification and fixing bottlenecks of a food manufacturing system using a simulation approach.

Javadi, Seyed Mahdi / Sadjadi, Seyed Jafar / Makui, Ahmad

Scientific reports

2023 Volume 13, Issue 1, Page(s) 11786

Abstract: In manufacturing systems, simulation modeling plays an important role in creating some changes instead of working on real systems. Manipulation in a real system is more costly than manipulation in a simulated model. In this research, we tried to use a ... ...

Abstract	In manufacturing systems, simulation modeling plays an important role in creating some changes instead of working on real systems. Manipulation in a real system is more costly than manipulation in a simulated model. In this research, we tried to use a simulation approach to recognize and minimize bottlenecks of a production line, which will decrease costs and improve productivity. To achieve our objectives, we chose a case and analyzed its production line. By using our case study strategy, we tried to collect our data and adapt a conceptual model of production processes drawing on an operation process chart (OPC). After that, we created a simulation model of the production processes by using the popular Arena simulation software 13.5. By running the Arena model, some bottlenecks were found. Ultimately, we proposed some solutions to obviate bottlenecks and reduce the total costs of production.
Language	English
Publishing date	2023-07-21
Publishing country	England
Document type	Journal Article
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-023-39025-5
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Article ; Online: Uremic pericarditis: a report of 30 cases and review of the literature.

Sadjadi, Seyed-Ali / Mashahdian, Ardavan

The American journal of case reports

2015 Volume 16, Page(s) 169–173

Abstract: Patient: Male, 71 • Male, 69 • . Female, 49.: Final diagnosis: Uremic pericarditis.: Symptoms: —: Medication: —: Clinical procedure: Hemodialysis.: Specialty: Nephrology.: Objective: Rare disease.: Background: Uremic pericarditis, ... ...

Abstract	Patient: Male, 71 • Male, 69 • . Female, 49. Final diagnosis: Uremic pericarditis. Symptoms: — Medication: — Clinical procedure: Hemodialysis. Specialty: Nephrology. Objective: Rare disease. Background: Uremic pericarditis, common at one time among dialysis patients, has become a rare entity in recent years. Due to its low incidence, its recognition has gained importance among internists, cardiologists, and nephrologists. It can be seen in predialysis patients and in dialysis patients who are on hemodialysis or peritoneal dialysis. Case report: We report 3 cases of uremic pericarditis and their presenting manifestations and review 30 cases we have treated. Among these patients, the traditional findings among patients with acute pericarditis such as chest pain, fever, electrocardiographic changes, and leukocytosis are uncommon. Pericardial friction rub has a relatively high incidence but its differentiation by an untrained ear, especially by a non-cardiologist, could be a major problem. Not infrequently, it is complicated by pre-tamponade or tamponade, requiring pericardiocentesis or pericardial surgery. Conclusions: Uremic pericarditis is a treatable, but not always a preventable, condition. Timely recognition of its presence and its efficient management are essential elements of successful treatment.
MeSH term(s)	Aged ; Coronary Artery Disease/complications ; Diabetes Complications ; Diagnosis, Differential ; Female ; Heart Failure/complications ; Humans ; Hypertension/complications ; Kidney Failure, Chronic/complications ; Male ; Middle Aged ; Pericardial Effusion/diagnosis ; Pericardial Effusion/etiology ; Pericardial Effusion/therapy ; Pericardiocentesis ; Pericarditis/diagnosis ; Pericarditis/etiology ; Pericarditis/therapy ; Renal Dialysis/methods ; Risk Factors ; Treatment Outcome ; Uremia/complications
Language	English
Publishing date	2015-03-22
Publishing country	United States
Document type	Case Reports ; Journal Article ; Review
ZDB-ID	2517183-5
ISSN	1941-5923 ; 1941-5923
ISSN (online)	1941-5923
ISSN	1941-5923
DOI	10.12659/AJCR.893140
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Book ; Online: NIST SRE CTS Superset

Sadjadi, Seyed Omid

A large-scale dataset for telephony speaker recognition

2021

Abstract: This document provides a brief description of the National Institute of Standards and Technology (NIST) speaker recognition evaluation (SRE) conversational telephone speech (CTS) Superset. The CTS Superset has been created in an attempt to provide the ... ...

Abstract	This document provides a brief description of the National Institute of Standards and Technology (NIST) speaker recognition evaluation (SRE) conversational telephone speech (CTS) Superset. The CTS Superset has been created in an attempt to provide the research community with a large-scale dataset along with uniform metadata that can be used to effectively train and develop telephony (narrowband) speaker recognition systems. It contains a large number of telephony speech segments from more than 6800 speakers with speech durations distributed uniformly in the [10s, 60s] range. The segments have been extracted from the source corpora used to compile prior SRE datasets (SRE1996-2012), including the Greybeard corpus as well as the Switchboard and Mixer series collected by the Linguistic Data Consortium (LDC). In addition to the brief description, we also report speaker recognition results on the NIST 2020 CTS Speaker Recognition Challenge, obtained using a system trained with the CTS Superset. The results will serve as a reference baseline for the challenge.
Keywords	Computer Science - Sound ; Computer Science - Artificial Intelligence ; Electrical Engineering and Systems Science - Audio and Speech Processing ; Statistics - Machine Learning
Subject code	410
Publishing date	2021-08-16
Publishing country	us
Document type	Book ; Online
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Article ; Online: Severe hypercalcemia complicating recovery of acute kidney injury due to rhabdomyolysis.

Hechanova, Lisa Aimee / Sadjadi, Seyed-Ali

The American journal of case reports

2014 Volume 15, Page(s) 393–396

Abstract: Background: Rhabdomyolysis is frequently complicated by multiple electrolyte abnormalities, including hyperkalemia, hyperphosphatemia, and hypo/hypercalcemia. Hypercalcemia can be severe and life-threatening.: Case report: A 23-year-old white male ... ...

Abstract	Background: Rhabdomyolysis is frequently complicated by multiple electrolyte abnormalities, including hyperkalemia, hyperphosphatemia, and hypo/hypercalcemia. Hypercalcemia can be severe and life-threatening. Case report: A 23-year-old white male suffered severe trauma to his lower extremities after a motor vehicle accident, leading to severe muscle damage, cardiac arrhythmia, cardiac arrest, and oliguric acute kidney injury (AKI), requiring hemodialysis treatment. As expected, he was hypocalcemic during the oliguric phase but during the diuretic phase he developed severe symptomatic hypercalcemia requiring hemodialysis treatment in spite of volume replacement and administration of pamidronate. Hypercalcemia reached a peak of 17.1 mg/dL, corrected for serum albumin and urine output was as high as 11.9 liters daily. Hypercalcemia lasted for 3 weeks and then it returned back to normal levels. Plasma levels of 25-OH and 1-25(OH)2 vitamin D were low, intact parathyroid hormone level was appropriately suppressed, and 24-hour urine calcium was 1194 mg (normal up to 350 mg/daily). Mobilization of calcium from calcium phosphate deposits in the injured muscles seems to be the main reason for hypercalcemia and hypercalciuria in rhabdomyolysis-induced AKI. Conclusions: Hypercalcemia is not uncommon during the recovery phase of ATN. Unattended, it can cause severe morbidity and even mortality. Fluid administration, pamidronate, and calcium-free dialysis are some methods used to correct severe hypercalcemia. Over time, hypercalcemia improves in almost all cases.
MeSH term(s)	Accidents, Traffic ; Acute Kidney Injury/complications ; Acute Kidney Injury/therapy ; Calcium/blood ; Calcium/urine ; Follow-Up Studies ; Humans ; Hypercalcemia/diagnosis ; Hypercalcemia/etiology ; Hypercalcemia/metabolism ; Male ; Positron-Emission Tomography ; Renal Dialysis/adverse effects ; Rhabdomyolysis/complications ; Rhabdomyolysis/diagnosis ; Severity of Illness Index ; Urinalysis ; Young Adult
Chemical Substances	Calcium (SY7Q814VUP)
Language	English
Publishing date	2014-09-14
Publishing country	United States
Document type	Case Reports ; Journal Article
ZDB-ID	2517183-5
ISSN	1941-5923 ; 1941-5923
ISSN (online)	1941-5923
ISSN	1941-5923
DOI	10.12659/AJCR.891046
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Article: Improving photocatalyst performance of CdTiO3 via binary Co@CdTiO3 and ternary Co@CdTiO3@S nanocomposites utilizing synergistic effect of adsorption-photocatalytic under sunlight

Tavakoli-Azar, Tayebeh / Mahjoub, Ali Reza / Sadjadi, Mirabdullah Seyed / Ghaznavi- Ghoushchi, M.B

Colloids and surfaces. 2021 Sept. 20, v. 625

2021

Abstract: Binary and ternary nanocomposites of Co@CdTiO₃ (Co@CTO) and Co@CdTiO₃@S (Co@CTO@S) were synthesized via the hydrothermal method and used as photocatalysts under visible-light. The structural properties, morphology, and size of the nanocomposites were ... ...

Abstract	Binary and ternary nanocomposites of Co@CdTiO₃ (Co@CTO) and Co@CdTiO₃@S (Co@CTO@S) were synthesized via the hydrothermal method and used as photocatalysts under visible-light. The structural properties, morphology, and size of the nanocomposites were evaluated by XRD, Fe-SEM, and TEM techniques, respectively. The impurities and chemical composition of the samples were characterized by FT-IR, Map, and EDX. BET analysis was also utilized to determine the specific surface area, total pore volume, and average pore diameter of the nanocomposites. The pore size distribution of the Co@CTO and Co@CTO@S was obtained through the BJH method. Optical properties were investigated via DRS spectra and the results showed a reduction in the band-gap energy due to the penetration of cobalt and sulfur in the structure of CdTiO₃ (CTO). Zeta potential measurements were utilized for determining the surface charge showed the change from + 24 mv to − 25 mv within the pHs range of 2–10. The photocatalytic performance of the CTO, Co@CTO, and Co@CTO@S was investigated by UV-Vis spectroscopy. The Co@CTO@S nanocomposite offered the highest photocatalytic performance in degrading Crystal-Violet (CV) dye as a pollutant (> 96% during 60 min adsorption and 30 min solar irradiation). The main responsible factors for this gain could be considered as: higher surface area, the synergistic effect of the adsorption-photodegradation process, as well as reducing the band-gap energy. Kinetics studies showed that the degradation of CV by Co@CTO@S followed the pseudo-second-order kinetics with R² = 0.9532. Its degradation rate was 22x and 225x faster than that of Co@CTO and CTO, respectively. The investigation of reusability and stability revealed that Co@CTO@S photocatalyst remained stable after five consecutive cycles as tested by the leaching process.
Keywords	adsorption ; chemical composition ; cobalt ; energy ; hot water treatment ; light ; nanocomposites ; pH ; photocatalysis ; photocatalysts ; pollutants ; porosity ; solar radiation ; sulfur ; surface area ; synergism ; ultraviolet-visible spectroscopy ; zeta potential
Language	English
Dates of publication	2021-0920
Publishing place	Elsevier B.V.
Document type	Article
ZDB-ID	1500517-3
ISSN	0927-7757
ISSN	0927-7757
DOI	10.1016/j.colsurfa.2021.126968
Database	NAL-Catalogue (AGRICOLA)

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Article: Adjunct Triptorelin in the Treatment of Obsessive-Compulsive Disorder in Clients Receiving Selective Serotonin Reuptake Inhibitors (SSRIs).

Nikzad, Faezeh / Sadjadi, Seyed Alireza / Mohammadpour, Amir Hooshang / Ziaee, Maliheh / Behdani, Fatemeh / Naghibi, Seyedeh Maryam / Nejatifard, Seyedeh Narges / Ghanbari, Mahdieh / Akhondpour Manteghi, Ali

Iranian journal of psychiatry

2022 Volume 16, Issue 4, Page(s) 444–450

Abstract: Objective: ...

Abstract	Objective:
Language	English
Publishing date	2022-01-17
Publishing country	Iran
Document type	Journal Article
ZDB-ID	2388800-3
ISSN	2008-2215 ; 1735-4587
ISSN (online)	2008-2215
ISSN	1735-4587
DOI	10.18502/ijps.v16i4.7232
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Article ; Online: Gemcitabine induced hemolytic uremic syndrome.

Sadjadi, Seyed-Ali / Annamaraju, Pavan

The American journal of case reports

2012 Volume 13, Page(s) 89–91

Abstract: Background: Gemcitabine is frequently used for the treatment of many cancers. Not infrequently it leads to development of hemolytic uremic syndrome, presenting with hemolytic anemia, acute kidney injury and occasionally peripheral edema, livedo ... ...

Abstract	Background: Gemcitabine is frequently used for the treatment of many cancers. Not infrequently it leads to development of hemolytic uremic syndrome, presenting with hemolytic anemia, acute kidney injury and occasionally peripheral edema, livedo reticularis and digital necrosis. Case report: A 78 year old man with non-small cell lung cancer developed uremic syndrome following treatment with multiple chemotherapy agents including gemcitabine. He was treated aggressively with hemodialysis and plasmapheresis. Initially he responded but upon attempts at decreasing the frequency of plasmapheresis, lactate dehydrogenase increased and platelet count decreased, indicating continuing hemolysis. Hemolysis responded to splenectomy but he continued to require hemodialysis treatment. Conclusions: Although many cases of gemcitabine induced HUS have been reported, its cause and pathogenesis remain unclear and it should be used with caution. Frequent monitoring of renal function and close observation of the patient are essential.
Language	English
Publishing date	2012-05-25
Publishing country	United States
Document type	Journal Article
ZDB-ID	2517183-5
ISSN	1941-5923 ; 1941-5923
ISSN (online)	1941-5923
ISSN	1941-5923
DOI	10.12659/AJCR.882858
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