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  1. Article: The impact of armed conflict on animal well-being and welfare, and analyzing damage assessment on the veterinary sector: The case of Ethiopia's Tigray region.

    Tedla, Mebrahtu G / Berhe, Kibrom F / Grmay, Kibrom M

    Heliyon

    2023  Volume 9, Issue 12, Page(s) e22681

    Abstract: Tigray war broke out on November 4, 2020, and lasted until November 3, 2022. The war has caused a significant loss of human life and a catastrophic economic and humanitarian crisis. The war affected the food and water supplies to farmers to care their ... ...

    Abstract Tigray war broke out on November 4, 2020, and lasted until November 3, 2022. The war has caused a significant loss of human life and a catastrophic economic and humanitarian crisis. The war affected the food and water supplies to farmers to care their livestock and this led to animal death, malnutrition, and suffering. In addition, a significant number of animals have been subjected to flee the region and killed during the warfare. The veterinary sector is significantly damaged and animals became a victim. Veterinarians and animal health workers have fled the region because of the war, and this adds an extra burden to the sector. Although the impact of this war on animal life, welfare and overall, on the livestock infrastructure is significant, no study has been conducted so far. We analyzed the level of damage to the veterinary sector and number of animal loss following the war. Our analytical study showed the war has claimed a total of 2,487,047 cattle, 1,690,096 sheep, 3,803,860 goat, 610,976 donkey, 4,280,815 poultry, and 231,985 beehives. Such loss led to an estimated total financial loss of 53.56 billion Ethiopian birr (∼1.01 billion USD). We also analyzed the destruction level of the veterinary infrastructures in percentage, and the associated financial loss due to facility damage and animal disappearances from the region. A complete destruction (100 %) of veterinary facilities was reported in 10 districts and this accounts to an estimated financial loss of 68.59 million Ethiopian birrs (1.3 million USD). In conclusion, Tigray war has caused an immense impact to animal welfare and veterinary sector and a collaborative effort between governmental and nongovernmental organizations, and professional bodies is required to restore to restor the sector. This study also highlighted how the war jeopardize animal right and wellbeing. Thus, we believe this study will be an input for national and international policy makers working on international convention for animal protection and rights.
    Language English
    Publishing date 2023-11-20
    Publishing country England
    Document type Journal Article
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2023.e22681
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Simulated gastric leachate of 3D printer metal-fill filaments induces cytotoxic effects in rat and human intestinal models.

    Hughes, Michael F / Clapper, Haley M / Tedla, Getachew / Sowers, Tyler D / Rogers, Kim R

    Toxicology in vitro : an international journal published in association with BIBRA

    2024  Volume 97, Page(s) 105805

    Abstract: Metals are used in 3-dimensional (3D) printer filaments in the manufacture of 3D printed objects. Exposure to the filaments, printed objects and emissions from printing may pose health risks from release of toxic metals. This study investigated the ... ...

    Abstract Metals are used in 3-dimensional (3D) printer filaments in the manufacture of 3D printed objects. Exposure to the filaments, printed objects and emissions from printing may pose health risks from release of toxic metals. This study investigated the cytotoxicity of extruded 3D printer filament leachates in rat and human intestinal cells. Copper-, bronze-, and steel-fill extruded filaments were incubated in acidic media for 2 h. Leachates were adjusted to pH 7 and cells exposed for 4 or 24 h. Concentration- and time-dependent decreases in rat and human cell viability were observed using a colorimetric assay and confirmed by microscopy. Copper- and bronze-fill leachates were more cytotoxic than steel. Copper-fill leachates had the highest copper concentrations by ICP-MS. Exposure to CuSO
    MeSH term(s) Humans ; Rats ; Animals ; Copper/toxicity ; Metals ; Intestines ; Steel
    Chemical Substances Copper (789U1901C5) ; Metals ; Steel (12597-69-2)
    Language English
    Publishing date 2024-03-06
    Publishing country England
    Document type Journal Article
    ZDB-ID 639064-x
    ISSN 1879-3177 ; 0887-2333
    ISSN (online) 1879-3177
    ISSN 0887-2333
    DOI 10.1016/j.tiv.2024.105805
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: The impact of armed conflict on animal well-being and welfare, and analyzing damage assessment on the veterinary sector

    Mebrahtu G. Tedla / Kibrom F. Berhe / Kibrom M. Grmay

    Heliyon, Vol 9, Iss 12, Pp e22681- (2023)

    The case of Ethiopia's Tigray region

    2023  

    Abstract: Tigray war broke out on November 4, 2020, and lasted until November 3, 2022. The war has caused a significant loss of human life and a catastrophic economic and humanitarian crisis. The war affected the food and water supplies to farmers to care their ... ...

    Abstract Tigray war broke out on November 4, 2020, and lasted until November 3, 2022. The war has caused a significant loss of human life and a catastrophic economic and humanitarian crisis. The war affected the food and water supplies to farmers to care their livestock and this led to animal death, malnutrition, and suffering. In addition, a significant number of animals have been subjected to flee the region and killed during the warfare. The veterinary sector is significantly damaged and animals became a victim. Veterinarians and animal health workers have fled the region because of the war, and this adds an extra burden to the sector. Although the impact of this war on animal life, welfare and overall, on the livestock infrastructure is significant, no study has been conducted so far. We analyzed the level of damage to the veterinary sector and number of animal loss following the war. Our analytical study showed the war has claimed a total loss of 2,487,047 cattle, 1,690,096 sheep, 3,803,860 goats, 610,976 donkey, 4,280,815 poultry, and 231,985 beehives. This caused an estimated total financial loss of 53.56 billion Ethiopian birr (∼1.01 billion USD). We also analyzed the destruction level of the veterinary infrastructures in percentage, and the associated financial loss due to facility damage and animal disappearances from the region. A complete destruction (100 %) of veterinary facilities was reported in 10 districts and this accounts to an estimated financial loss of 68.59 million Ethiopian birrs (1.3 million USD). In conclusion, Tigray war has caused an immense impact to animal welfare and veterinary sector and a collaborative effort between governmental and nongovernmental organizations, and professional bodies is required to restore the sector. This study also highlighted how the war jeopardize animal right and wellbeing. Thus, we believe this study will be an input for national and international policy makers working on international convention for animal protection and rights.
    Keywords Animal victim ; Animal welfare ; Damage analysis ; Financial loss ; Tigray war ; Veterinary sector ; Science (General) ; Q1-390 ; Social sciences (General) ; H1-99
    Subject code 390
    Language English
    Publishing date 2023-12-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Establishing a Kidney Transplantation Program in a Resource-limited Country: The Experience of Rwanda.

    Ahmed, Momina M / Neil, Kara L / Gasana, Afrika G / Leichtman, Alan / Brown, Lloyd / Tedla, Fasika / Satarino, Colleen / Sendegeya, Augustin / Rusanganwa, Vincent / Punch, Jeffrey / Ntihabose, Corneille

    Transplantation

    2024  Volume 108, Issue 5, Page(s) 1033–1035

    MeSH term(s) Kidney Transplantation ; Rwanda ; Humans ; Developing Countries ; Health Resources ; Program Development
    Language English
    Publishing date 2024-04-24
    Publishing country United States
    Document type Letter ; Journal Article
    ZDB-ID 208424-7
    ISSN 1534-6080 ; 0041-1337
    ISSN (online) 1534-6080
    ISSN 0041-1337
    DOI 10.1097/TP.0000000000004923
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Validity and reliability of Squegg device in measuring isometric handgrip strength.

    Bairapareddy, K C / Khaleel, A / Akbar, S / Maherban, H / Mehdiyeva, F / Rasti, F / Tamim, M / Abdelbasset, W K / Ezzat, W / Reddy, R S / Tedla, J S / Ramakrshnan, S / Hussein, R S / Alaparthi, G K / Elsayed, S H

    European review for medical and pharmacological sciences

    2023  Volume 27, Issue 21, Page(s) 10247–10254

    Abstract: Objective: The quantitative measurement of handgrip strength is important in assessing and charting the progress of patients with neuromuscular diseases. The aim of this research was to determine the intra-rater and inter-rater reliability and the ... ...

    Abstract Objective: The quantitative measurement of handgrip strength is important in assessing and charting the progress of patients with neuromuscular diseases. The aim of this research was to determine the intra-rater and inter-rater reliability and the validity of the Squegg digital dynamometer.
    Subjects and methods: Twenty-one females and nine male participants with an age range between 18 and 40 years volunteered for the study. Three testers each took three measurements with a Squegg device and a Jamar dynamometer using standardized measurement techniques. Intra- and inter-tester reliability were calculated using the intra-class correlation coefficient (ICC). To investigate the relationship between hand measures and isometric handgrip strength, the Pearson correlation coefficient test was used. To determine the agreement between the two devices, a Bland Altman plot was constructed, and the concurrent validity of Squegg was calculated.
    Results: The intra-rater reliability coefficients for both Jamar and Squegg were greater than 0.99 for all three testers, indicating excellent intra-rater reliability. The inter-rater reliability of Jamar (ICC=0.93) and Squegg (ICC=0.87) was excellent. With an ICC of 0.844 and an r-value of 0.720, Squegg with Jamar demonstrates good validity and statistical significance (p=0.001).
    Conclusions: The isometric handgrip strength and hand measures showed a moderate correlation in the study population. The Squegg isometric handgrip dynamometer has good concurrent validity and great intra- and inter-rater reliability in healthy individuals. The validity of Squegg in patients with neuromuscular diseases that affect hand function has to be investigated further.
    MeSH term(s) Female ; Humans ; Male ; Adolescent ; Young Adult ; Adult ; Hand Strength ; Reproducibility of Results ; Muscle Strength Dynamometer ; Health Status ; Neuromuscular Diseases
    Language English
    Publishing date 2023-11-17
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 605550-3
    ISSN 2284-0729 ; 1128-3602 ; 0392-291X
    ISSN (online) 2284-0729
    ISSN 1128-3602 ; 0392-291X
    DOI 10.26355/eurrev_202311_34300
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: A cross-sectional survey and follow up study on major dairy health problems in large and small scale urban farms in Mekelle, Tigray, Ethiopia.

    Tedla, Mebrahtu / Mehari, Feven / Kebede, Hassen

    BMC research notes

    2018  Volume 11, Issue 1, Page(s) 236

    Abstract: Objective: This study was conducted with the objective of estimating the incidence of major dairy health problems in the area.: Result: From a cross-sectional survey (n = 475) and follow up study (n = 68), an overall incidence of 43.00 and 29.02% was ...

    Abstract Objective: This study was conducted with the objective of estimating the incidence of major dairy health problems in the area.
    Result: From a cross-sectional survey (n = 475) and follow up study (n = 68), an overall incidence of 43.00 and 29.02% was reported respectively. This study showed biting fly (9.51%), respiratory problems (7.80%), mastitis (5.13%), actinomycosis (5.12%), dystocia (4.42%), endoparasites (3.81%), retention fetal membrane (3.63%), tick infestation (2.91%), lameness (2.94%), vaginal and uterine prolepses (2.51%), skin related problem (1.70%) and abortion (1.70%) were the main dairy health problems identified. In addition, the follow up study revealed; retention fetal membrane (5.91%), tick infestation (5.91%), respiratory problem (2.91%), mastitis (2.94%), endoparasites (2.94%), lameness (2.94%), dystocia (2.94%), actinomycosis (1.53%) and skin related problems (1.53%). The incidence of dairy reproductive problems showed statistically significant variation among local and cross breeds (P < 0.05). Incidence of infectious diseases among dairy cows managed under intensive and semi-intensive management systems showed a significant difference (P < 0.05). Moreover, incidence of physical injury was also showed a significant difference among animal breeds and management system (P < 0.05). However, reproductive problems among management system and infectious diseases among breeds showed a significant difference (P > 0.05). Overall, this study showed dairy animals are exposed to various type of diseases.
    MeSH term(s) Animals ; Cattle ; Cattle Diseases/epidemiology ; Communicable Diseases/epidemiology ; Communicable Diseases/veterinary ; Cross-Sectional Studies ; Dairying/statistics & numerical data ; Ethiopia/epidemiology ; Farms/statistics & numerical data ; Female ; Follow-Up Studies ; Parasitic Diseases, Animal/epidemiology ; Pregnancy ; Pregnancy Complications/epidemiology ; Pregnancy Complications/veterinary
    Language English
    Publishing date 2018-04-10
    Publishing country England
    Document type Journal Article
    ZDB-ID 2413336-X
    ISSN 1756-0500 ; 1756-0500
    ISSN (online) 1756-0500
    ISSN 1756-0500
    DOI 10.1186/s13104-018-3347-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Correlation and comparison of quadriceps endurance and knee joint position sense in individuals with and without unilateral knee osteoarthritis.

    Saeed Alshahrani, Mastour / Reddy, Ravi Shankar / Asiri, Faisal / Tedla, Jaya Shanker / Alshahrani, Adel / Kandakurti, Praveen Kumar / Kakaraparthi, Venkata Nagaraj

    BMC musculoskeletal disorders

    2022  Volume 23, Issue 1, Page(s) 444

    Abstract: Background: Knee osteoarthritis (KOA) is a painful degenerative joint disease that may limit activities of daily living. This study aimed to determine the relationship between quadriceps endurance and knee joint position sense (JPS) in KOA individuals ... ...

    Abstract Background: Knee osteoarthritis (KOA) is a painful degenerative joint disease that may limit activities of daily living. This study aimed to determine the relationship between quadriceps endurance and knee joint position sense (JPS) in KOA individuals and compare the quadriceps endurance and knee JPS with and without KOA.
    Methods: This comparative cross-sectional study was conducted in medical rehabilitation clinics, King Khalid University, Saudi Arabia. This study recruited 50 individuals diagnosed with unilateral KOA (mean age = 67.10 ± 4.36 years) and 50 asymptomatic individuals (mean age = 66.50 ± 3.63 years). Quadriceps isometric endurance capacity (sec) was measured using a fatigue resistance test, and knee JPS (degrees) were assessed using a digital inclinometer and evaluated in sitting and standing positions.
    Results: Quadriceps isometric endurance showed a significant moderate negative correlation with knee JPS in 20° of flexion (r = -0.48, p < 0.001); 40° of flexion: r = -0.62, p < 0.001; 60° of flexion: r = -0.58, p < 0.001) in sitting and 20° of flexion (r = -0.25, p = 0.084) in standing position in KOA individuals. When compared to the asymptomatic, the quadriceps endurance was lower (p < 0.001), and knee joint position errors were larger (p < 0.001) in KOA individuals.
    Conclusion: Results of this study showed that quadriceps endurance capacity is negatively associated with knee JPS. KOA individuals demonstrated lower quadriceps endurance and larger JPS compared to asymptomatic.
    MeSH term(s) Activities of Daily Living ; Aged ; Cross-Sectional Studies ; Humans ; Knee Joint ; Middle Aged ; Osteoarthritis, Knee ; Proprioception
    Language English
    Publishing date 2022-05-12
    Publishing country England
    Document type Journal Article
    ZDB-ID 2041355-5
    ISSN 1471-2474 ; 1471-2474
    ISSN (online) 1471-2474
    ISSN 1471-2474
    DOI 10.1186/s12891-022-05403-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Low global frontal brain activity is associated with non-planned or impulsive suicide attempts. A preliminary study.

    Cáceda, Ricardo / Mirmina, Julianne / Kim, Diane J / Rafiaa, Marianne / Carbajal, Jessica M / Akram, Faisal / Lau, Jaisy / Chacko, Mason / Tedla, Alemante / Teng, York / Perlman, Greg

    Journal of affective disorders

    2023  Volume 326, Page(s) 44–48

    Abstract: Background: Suicide prevention is limited by the frequent non-planned or impulsive nature of suicidal behavior. For instance, 25-62 % of suicide attempts, occur within 30 min of the onset of suicidal ideation. We aimed to examine frontal brain activity ... ...

    Abstract Background: Suicide prevention is limited by the frequent non-planned or impulsive nature of suicidal behavior. For instance, 25-62 % of suicide attempts, occur within 30 min of the onset of suicidal ideation. We aimed to examine frontal brain activity in depressed patients following a suicide attempt and its relationship with the duration of the suicidal process.
    Methods: We recruited 35 adult patients within three days of a suicide attempt of at least moderate lethality. Duration of the suicidal process was recorded in a semi-structured interview, including suicide contemplation (time from onset of suicidal ideation to decision to kill oneself) and suicide action intervals (time from the decision to kill oneself to suicide attempt). Resting state EEG data from AF7, AF8, TP9 and TP10 leads was collected with a portable MUSE 2 headband system. The average frequency values throughout a 5-minute portable EEG recording were extracted for delta (1-4 Hz), theta (4-8 Hz), alpha (8-13 Hz), and beta (13-30 Hz) waves.
    Results: Delta (r = 0.450, p = 0.021) and theta power (r = 0.395, p = 0.044) were positively correlated with the duration of the suicide action interval. There were no significant correlations of the suicide contemplation interval with clinical or EEG measures. Patients with suicide action interval shorter than 30 min showed lower delta power (U = 113, p = 0.049) compared with those with longer duration.
    Conclusions: Lower theta and delta activity may reflect hindered cognitive control and inhibition in impulsive suicide attempters. Portable EEG may provide a valuable tool for clinical research and in the management of acutely suicidal patients.
    MeSH term(s) Adult ; Humans ; Suicide, Attempted/prevention & control ; Suicide, Attempted/psychology ; Brain ; Suicidal Ideation ; Impulsive Behavior/physiology ; Suicide Prevention
    Language English
    Publishing date 2023-01-25
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 135449-8
    ISSN 1573-2517 ; 0165-0327
    ISSN (online) 1573-2517
    ISSN 0165-0327
    DOI 10.1016/j.jad.2023.01.084
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Effects of patient-specific three-dimensional lumbar traction on pain and functional disability in patients with lumbar intervertebral disc prolapse.

    Asiri, F / Tedla, J S / D Alshahrani, M S / Ahmed, I / Reddy, R S / Gular, K

    Nigerian journal of clinical practice

    2020  Volume 23, Issue 4, Page(s) 498–502

    Abstract: Background: Prolapsed lumbar intervertebral disc is one of the most prevalent causes of low back pain and traction is one of the most common physical therapy treatments offered to affected patients. Advancements in traction equipment are needed to ... ...

    Abstract Background: Prolapsed lumbar intervertebral disc is one of the most prevalent causes of low back pain and traction is one of the most common physical therapy treatments offered to affected patients. Advancements in traction equipment are needed to ensure their effectiveness in clinical situations.
    Aims: The objective of the study was to find out the effect of patient-specific three-dimensional lumbar traction on pain and functional disability in individuals with lumbar intervertebral disc prolapse.
    Subjects and methods: Original article and Experimental design. Twenty-five participants (age range: 34-67 years) diagnosed with lumbar intervertebral disc prolapse were included in this study. Patient-specific three-dimensional lumbar traction was given as three sessions per week for the duration of one month. All participants completed a 10-cm visual analog pain scale and pain pressure threshold to assess pain and the Oswestry disability index to assess the functional disability.
    Results: On pre to post interventions, a significant change in mean values were found for visual analog scale pain score, pain pressure threshold, and Oswestry disability index (P < 0.001). The pain intensity was reduced from 8.5 to 3.2, pain pressure threshold increased from 0.7 to 1.6 kg/cm
    Conclusion: Twelve sessions of patient-specific three-dimensional lumbar traction promoted a reduction in pain and improvement in functional disability among subjects with lumbar intervertebral disc prolapse.
    MeSH term(s) Adult ; Aged ; Female ; Humans ; Intervertebral Disc Degeneration/therapy ; Intervertebral Disc Displacement/therapy ; Low Back Pain/therapy ; Male ; Middle Aged ; Physical Therapy Modalities ; Prolapse ; Traction/methods ; Treatment Outcome ; Visual Analog Scale
    Language English
    Publishing date 2020-04-03
    Publishing country India
    Document type Journal Article
    ZDB-ID 1458330-6
    ISSN 1119-3077
    ISSN 1119-3077
    DOI 10.4103/njcp.njcp_285_19
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Antihypertensive Medications and Change in Stages of Chronic Kidney Disease.

    Komaroff, Marina / Tedla, Fasika / Helzner, Elizabeth / Joseph, Michael A

    International journal of chronic diseases

    2018  Volume 2018, Page(s) 1382705

    Abstract: Objectives: The goal of this study is to estimate the change in the relationships between use of five classes of antihypertensive medications and stages of Chronic Kidney Disease (CKD) in American adults treated for hypertension.: Methods: The US ... ...

    Abstract Objectives: The goal of this study is to estimate the change in the relationships between use of five classes of antihypertensive medications and stages of Chronic Kidney Disease (CKD) in American adults treated for hypertension.
    Methods: The US National Health and Nutrition Examination Survey (NHANES) data sets 1999-2012 were used with the final analytical sample of 3,045 participants. Population prevalence estimates were calculated using the NHANES survey design weights. Inferential analyses were done with binomial logistic regression models.
    Results: The odds of advanced (3, 4, and 5 combined) versus early CKD stages (1 and 2 combined) were significantly higher among patients treated with Angiotensin Receptor Blockers (ARB) versus those not treated with ARB in 2009-2012 (adjusted odds ratio (95% confidence interval) = 2.52 (1.32-4.80)). From 1999 to 2012, the increase in this relationship was significant (
    Conclusion: Aggressive pharmacological management of hypertension with ARB as add-on therapy may have accelerated kidney damage in American adults. However, prospective longitudinal studies are needed to establish proper temporal sequence in this relationship.
    Language English
    Publishing date 2018-02-25
    Publishing country Egypt
    Document type Journal Article
    ISSN 2356-6981
    ISSN 2356-6981
    DOI 10.1155/2018/1382705
    Database MEDical Literature Analysis and Retrieval System OnLINE

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