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  1. Article ; Online: Bryan Traynor: serious science from a funny fellow.

    Williams, Ruth

    The Lancet. Neurology

    2018  Volume 18, Issue 8, Page(s) 720

    MeSH term(s) Amyotrophic Lateral Sclerosis ; Humans ; Neurology
    Language English
    Publishing date 2018-11-12
    Publishing country England
    Document type Interview
    ZDB-ID 2079704-7
    ISSN 1474-4465 ; 1474-4422
    ISSN (online) 1474-4465
    ISSN 1474-4422
    DOI 10.1016/S1474-4422(18)30286-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Professor Bryan F Warren--obituary.

    Shepherd, Neil A / Novelli, Marco R / Williams, Geraint T

    Histopathology

    2012  Volume 61, Issue 1, Page(s) 138–139

    MeSH term(s) Gastroenterology/education ; Gastroenterology/history ; History, 20th Century ; History, 21st Century ; Humans ; Inflammatory Bowel Diseases/history ; Inflammatory Bowel Diseases/pathology ; Pathology, Surgical/education ; Pathology, Surgical/history ; United Kingdom
    Language English
    Publishing date 2012-07
    Publishing country England
    Document type Biography ; Historical Article ; Journal Article ; Portraits
    ZDB-ID 131914-0
    ISSN 1365-2559 ; 0309-0167
    ISSN (online) 1365-2559
    ISSN 0309-0167
    DOI 10.1111/j.1365-2559.2012.04325.x
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    Zs.A 1328: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (1.OG)
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  3. Article ; Online: Professor Bryan F Warren (15 April 1958-28 March 2012): an appreciation.

    Shepherd, Neil A / Novelli, Marco R / Williams, Geraint T

    The Journal of pathology

    2012  Volume 227, Issue 3, Page(s) e3–4

    MeSH term(s) England ; Gastroenterology/education ; Gastroenterology/history ; History, 20th Century ; History, 21st Century ; Humans ; Inflammatory Bowel Diseases/history ; Inflammatory Bowel Diseases/pathology ; Pathology, Clinical/education ; Pathology, Clinical/history
    Language English
    Publishing date 2012-07
    Publishing country England
    Document type Biography ; Historical Article ; Journal Article ; Portraits
    ZDB-ID 3119-7
    ISSN 1096-9896 ; 0022-3417
    ISSN (online) 1096-9896
    ISSN 0022-3417
    DOI 10.1002/path.4048
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    Ud II Zs.12: Show issues Location:
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  4. Article ; Online: Professor Bryan F Warren: an appreciation (15 April 1958-28 March 2012).

    Shepherd, Neil A / Novelli, Marco R / Williams, Geraint T

    Journal of clinical pathology

    2012  Volume 65, Issue 9, Page(s) 863–864

    MeSH term(s) Biomedical Research/history ; Gastroenterology/education ; Gastroenterology/history ; History, 20th Century ; History, 21st Century ; Humans ; Pathology/education ; Pathology/history ; Teaching/history ; United Kingdom
    Language English
    Publishing date 2012-09
    Publishing country England
    Document type Biography ; Historical Article ; Journal Article
    ZDB-ID 80261-x
    ISSN 1472-4146 ; 0021-9746
    ISSN (online) 1472-4146
    ISSN 0021-9746
    DOI 10.1136/jclinpath-2012-200925
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  5. Article ; Online: A New Dawn for Aldosterone as a Therapeutic Target in Hypertension.

    Williams, Bryan

    JAMA

    2023  Volume 330, Issue 12, Page(s) 1138–1139

    MeSH term(s) Humans ; Aldosterone ; Hypertension/drug therapy ; Molecular Targeted Therapy
    Chemical Substances Aldosterone (4964P6T9RB)
    Language English
    Publishing date 2023-08-29
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 2958-0
    ISSN 1538-3598 ; 0254-9077 ; 0002-9955 ; 0098-7484
    ISSN (online) 1538-3598
    ISSN 0254-9077 ; 0002-9955 ; 0098-7484
    DOI 10.1001/jama.2023.17087
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    Ua VI Zs.88: Show issues Location:
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  6. Article ; Online: Evaluation of the utility of NEWS2 during the COVID-19 pandemic.

    Williams, Bryan

    Clinical medicine (London, England)

    2022  Volume 22, Issue 6, Page(s) 539–543

    Abstract: The emergence of the COVID-19 pandemic resulted in a dramatic increase in acutely ill patients presenting to hospitals with life-threatening acute respiratory disease. There was an immediate need for effective triage systems to facilitate clinical ... ...

    Abstract The emergence of the COVID-19 pandemic resulted in a dramatic increase in acutely ill patients presenting to hospitals with life-threatening acute respiratory disease. There was an immediate need for effective triage systems to facilitate clinical decision making. This review assesses the performance of the National Early Warning Score 2 (NEWS2) in two contexts. Firstly, the ability to detect acute illness severity and likely clinical deterioration in patients presenting to hospitals with COVID-19. Secondly, the use of NEWS2 in the longitudinal monitoring to detect acute clinical deterioration in hospitalised patients with COVID-19. NEWS2 appeared to be at least comparable and, often, superior to other scoring systems (such as qSOFA and CURB-65), and provided an earlier alert of deterioration. A NEWS2 of 5 had high short-term sensitivity within and was unlikely to miss patients with COVID-19 who go on to deteriorate, but this comes with moderate specificity. However, the specificity of these systems is likely underestimated because preventing deterioration is their purpose.NEWS2 is an adjunct to clinical decision making and has served that purpose during the COVID-19 pandemic, playing an important role in communicating illness severity, clinical deterioration, triaging patients to appropriate levels of care and prompting completion of treatment escalation plans for those with high scores and at imminent risk of deterioration.
    MeSH term(s) Humans ; COVID-19 ; Pandemics ; Clinical Deterioration ; Triage/methods
    Language English
    Publishing date 2022-11-21
    Publishing country England
    Document type Review ; Journal Article
    ZDB-ID 2048646-7
    ISSN 1473-4893 ; 1470-2118
    ISSN (online) 1473-4893
    ISSN 1470-2118
    DOI 10.7861/clinmed.2022-news-covid
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    Zs.A 5439: Show issues Location:
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  7. Article ; Online: The National Early Warning Score: from concept to NHS implementation.

    Williams, Bryan

    Clinical medicine (London, England)

    2022  Volume 22, Issue 6, Page(s) 499–505

    Abstract: This year is the 10th anniversary since the launch of the National Early Warning Score (NEWS) by the Royal College of Physicians in 2012. This review reflects on the journey, from the nascent concept of a standardised system to detect acute illness ... ...

    Abstract This year is the 10th anniversary since the launch of the National Early Warning Score (NEWS) by the Royal College of Physicians in 2012. This review reflects on the journey, from the nascent concept of a standardised system to detect acute illness severity and clinical deterioration through to the adoption of NEWS2 by the NHS and, ultimately, its incorporation into quality indicators of acute care provision. The impact of NEWS/NEWS2 on the transformation of provision and configuration and training of acute care teams in hospitals is reviewed. User feedback has been key in iterating guidance on the use of NEWS/NEWS2 and key elements of this are discussed. The ultimate aim of NEWS was to improve patient outcomes with acute illness or deterioration and the impact on outcomes is now becoming apparent but, paradoxically, an effective response can eliminate the link between the score and the ultimate outcome. This review concludes with a reflection on what the next 10 years may bring, particularly with the digital transformation of healthcare and its potential impact on scoring systems, as well as the necessary permeation of NEWS2 beyond the acute hospital setting into emergency response triage in primary and community care settings.Ten years on, via NEWS/NEWS2, the NHS is the first healthcare system globally with a 'common language' of illness severity and a standardised early warning system for acute clinical illness and deterioration, a system that is now being replicated in many other areas of the world.
    MeSH term(s) Humans ; Early Warning Score ; State Medicine ; Critical Care ; Educational Status ; Hospitals
    Language English
    Publishing date 2022-11-21
    Publishing country England
    Document type Review ; Journal Article
    ZDB-ID 2048646-7
    ISSN 1473-4893 ; 1470-2118
    ISSN (online) 1473-4893
    ISSN 1470-2118
    DOI 10.7861/clinmed.2022-news-concept
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    Zs.A 5439: Show issues Location:
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  8. Article ; Online: Renin-angiotensin system inhibitors in hospitalised patients with COVID-19.

    Williams, Bryan

    The Lancet. Respiratory medicine

    2021  Volume 9, Issue 3, Page(s) 221–222

    MeSH term(s) Angiotensin Receptor Antagonists ; COVID-19 ; Hospitals ; Humans ; Prospective Studies ; Renin-Angiotensin System ; SARS-CoV-2
    Chemical Substances Angiotensin Receptor Antagonists
    Language English
    Publishing date 2021-01-07
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 2686754-0
    ISSN 2213-2619 ; 2213-2600
    ISSN (online) 2213-2619
    ISSN 2213-2600
    DOI 10.1016/S2213-2600(21)00003-5
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    Zs.A 7041: Show issues Location:
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  9. Article ; Online: Renin Angiotensin System Inhibition as treatment for Covid-19?

    Williams, Professor Bryan

    EClinicalMedicine

    2021  Volume 37, Page(s) 101023

    Language English
    Publishing date 2021-07-13
    Publishing country England
    Document type Journal Article
    ISSN 2589-5370
    ISSN (online) 2589-5370
    DOI 10.1016/j.eclinm.2021.101023
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Book ; Online: Mamã, porque sou uma ave?

    Wells, Anne Marie / Azul, Anabela Marisa / Williams, Bryan

    2015  

    Abstract: Uma ave, curiosa, ... ...

    Abstract Uma ave, curiosa, pergunta
    Size 1 electronic resource (55 pages)
    Publisher Coimbra University Press
    Document type Book ; Online
    Note Open Access
    HBZ-ID HT020589221
    ISBN 9789892607368 ; 9892607368
    DOI 10.14195/978-989-26-0736-8
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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