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  1. Book: Chronopharmakologie

    Lemmer, Björn

    biologische Rhythmen und Arzneimittelwirkung ; mit 26 Tabellen

    2012  

    Author's details Björn Lemmer
    Keywords Circadian Rhythm ; Pharmacology ; Chronopharmakologie
    Language German
    Size XI, 203 S. : Ill., graph. Darst.
    Edition 4., überarb. und erw. Aufl.
    Publisher Wiss. Verl.-Ges
    Publishing place Stuttgart
    Publishing country Germany
    Document type Book
    HBZ-ID HT016959953
    ISBN 978-3-8047-2786-1 ; 3-8047-2786-7
    Database Catalogue ZB MED Medicine, Health

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  2. Article ; Online: Caelius Aurelianus' textbook on medicine of the fifth century: rhythm in asthma, pain, and drug effects.

    Lemmer, Björn

    Chronobiology international

    2019  Volume 36, Issue 7, Page(s) 883–885

    Abstract: Caelius Aurelianus was a Greek-Roman physician in the fifth century. He translated the work of Soranus from Ephesus into Latin and extended the medical knowledge of his time in several textbooks. His book " ...

    Abstract Caelius Aurelianus was a Greek-Roman physician in the fifth century. He translated the work of Soranus from Ephesus into Latin and extended the medical knowledge of his time in several textbooks. His book "
    MeSH term(s) Analgesics/history ; Asthma/history ; Chronobiology Phenomena ; Circadian Rhythm ; History, Ancient ; Humans ; Lung Diseases/history ; Pain/drug therapy ; Roman World ; Seasons ; Toothache/history
    Chemical Substances Analgesics
    Language English
    Publishing date 2019-04-05
    Publishing country England
    Document type Historical Article ; Letter
    ZDB-ID 998996-1
    ISSN 1525-6073 ; 0742-0528
    ISSN (online) 1525-6073
    ISSN 0742-0528
    DOI 10.1080/07420528.2019.1595639
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: No correlation between lunar and menstrual cycle - an early report by the french physician J. A. Murat in 1806.

    Lemmer, Björn

    Chronobiology international

    2019  Volume 36, Issue 5, Page(s) 587–590

    Abstract: Jean Arnaud Murat was a physician at the Medical School of Montpellier in France. In 1806 he published his outstanding book "De L'Influence de la Nuit sur les Maladies ou Traité des Maladies Nocturne". In his book he concentrated on the following ... ...

    Abstract Jean Arnaud Murat was a physician at the Medical School of Montpellier in France. In 1806 he published his outstanding book "De L'Influence de la Nuit sur les Maladies ou Traité des Maladies Nocturne". In his book he concentrated on the following questions: - Does the night has an influence on a disease? - Are there diseases in which this is more or less obvious? - What is the physical background of this influence? Murat described in detail certain diseases which dominate at night and he concluded that the most evident motivation for his observations is the constant and periodic movement of the earth around its axis, resulting in a period of about 24 h, and the elliptic rotation around the sun. Most important Murat presented for the first time data that the menstrual cycle is not governed by the lunar cycle.
    MeSH term(s) Circadian Rhythm/physiology ; Female ; France ; History, 19th Century ; Humans ; Menstrual Cycle/physiology ; Moon ; Physicians/history
    Language English
    Publishing date 2019-02-22
    Publishing country England
    Document type Historical Article ; Journal Article
    ZDB-ID 998996-1
    ISSN 1525-6073 ; 0742-0528
    ISSN (online) 1525-6073
    ISSN 0742-0528
    DOI 10.1080/07420528.2019.1583669
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: The physiologist Johann Autenrieth (1772-1835) at Tübingen University: early reports on biological rhythms and their use for medical lectures.

    Lemmer, Björn

    Chronobiology international

    2018  Volume 36, Issue 3, Page(s) 304–306

    Abstract: Johann, Heinrich, Ferdinand von Autenrieth [1772-1835], was a teacher of anatomy, physiology and pharmacology at the University of Tübingen, Germany. He was the author of a famous textbook on Physiology and one of the earliest pharmacologists [ ... ...

    Abstract Johann, Heinrich, Ferdinand von Autenrieth [1772-1835], was a teacher of anatomy, physiology and pharmacology at the University of Tübingen, Germany. He was the author of a famous textbook on Physiology and one of the earliest pharmacologists [Öffentlicher Lehrer der Arzneykunst]. In his textbooks, he presented a lot of information that and how biological rhythms influenced physiological functions in the human body, the book was used for his medical lectures for students. He can be regarded as on of the earliest chronophysiologists. Most important, he assumed a chemical stimulation responsible for generating the periodicities in the human body.
    MeSH term(s) Animals ; Circadian Rhythm/physiology ; Germany ; History, 18th Century ; History, 19th Century ; Humans ; Research Personnel/history ; Students ; Universities/history ; Zebrafish/physiology
    Language English
    Publishing date 2018-12-21
    Publishing country England
    Document type Biography ; Historical Article ; Letter
    ZDB-ID 998996-1
    ISSN 1525-6073 ; 0742-0528
    ISSN (online) 1525-6073
    ISSN 0742-0528
    DOI 10.1080/07420528.2018.1550653
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Book: Chronopharmakologie

    Lemmer, Björn

    Tagesrhythmen und Arzneimittelwirkung ; 22 Tabellen

    2004  

    Author's details Björn Lemmer
    Keywords Circadian Rhythm ; Pharmacology ; Chronopharmakologie
    Language German
    Size IX, 180 S. : Ill., graph. Darst.
    Edition 3., völlig neu bearb. Aufl.
    Publisher Wiss. Verl.-Ges
    Publishing place Stuttgart
    Publishing country Germany
    Document type Book
    HBZ-ID HT014018596
    ISBN 3-8047-1304-1 ; 978-3-8047-1304-8
    Database Catalogue ZB MED Medicine, Health

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  6. Article: Signal Transduction and Chronopharmacology of Regulation of Circadian Cardiovascular Rhythms in Animal Models of Human Hypertension.

    Lemmer, Björn

    Heart failure clinics

    2017  Volume 13, Issue 4, Page(s) 739–757

    Abstract: Inbred strains of rats can be used as models of human hypertension to evaluate mechanisms of regulation of the circadian rhythms underlying hypertension. Blood pressure and heart rate rhythms in rodents are endogenous (circadian). Studies have been ... ...

    Abstract Inbred strains of rats can be used as models of human hypertension to evaluate mechanisms of regulation of the circadian rhythms underlying hypertension. Blood pressure and heart rate rhythms in rodents are endogenous (circadian). Studies have been performed in rats on the turnover of norepinephrine, on processes of signal transduction in the beta-adrenoceptor-adenylate cyclase-cyclic AMP-phosphodiesterase system and in the renin-angiotensin-aldosterone system, and on circadian rhythms in blood pressure and heart rate using radiotelemetry. The findings allowed a better understanding of the circadian phase-dependent kinetics and effects of cardiovascular active drugs (chronopharmacology) used in humans.
    Language English
    Publishing date 2017-10
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2212019-1
    ISSN 1551-7136
    ISSN 1551-7136
    DOI 10.1016/j.hfc.2017.05.009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Auch in Stockholm tickt nun die innere Uhr – Nobelpreis für die circadianen Rhythmen.

    Lemmer, Björn

    Deutsche medizinische Wochenschrift (1946)

    2017  Volume 142, Issue 25, Page(s) 1897–1900

    Title translation The Circadian Clock is Now Ticking Even in Stockholm - Nobel Prize in Medicine 2017.
    MeSH term(s) Circadian Clocks ; History of Medicine ; History, 21st Century ; Humans ; Nobel Prize
    Language German
    Publishing date 2017-12-14
    Publishing country Germany
    Document type Historical Article ; Journal Article
    ZDB-ID 200446-x
    ISSN 1439-4413 ; 0012-0472
    ISSN (online) 1439-4413
    ISSN 0012-0472
    DOI 10.1055/s-0043-122203
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Licht und Medizin.

    Lemmer, Björn

    Deutsche medizinische Wochenschrift (1946)

    2016  Volume 141, Issue 25, Page(s) 1840–1844

    Abstract: There would be no life without light. The rotation of the earth around its axis has introduced the development of biological clocks in all living subjects regulating all functions of the body. The rhythms best described are the 24-hour/circadian and the ... ...

    Title translation Light and Medicine.
    Abstract There would be no life without light. The rotation of the earth around its axis has introduced the development of biological clocks in all living subjects regulating all functions of the body. The rhythms best described are the 24-hour/circadian and the seasonal rhythms. The rhythmic composition around the body clock has great impact on health and disease, both in diagnostics and treatment. Nowadays, bright light, e.g. in seasonal affective disorder, can be regarded as a drug, being even more effective than selective serotonin reuptake inhibitors.
    MeSH term(s) Circadian Rhythm/radiation effects ; Evidence-Based Medicine ; Humans ; Light ; Lighting/methods ; Models, Biological ; Phototherapy/methods ; Seasonal Affective Disorder/physiopathology ; Seasonal Affective Disorder/prevention & control ; Seasons
    Language German
    Publishing date 2016-12
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 200446-x
    ISSN 1439-4413 ; 0012-0472
    ISSN (online) 1439-4413
    ISSN 0012-0472
    DOI 10.1055/s-0042-109421
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Sanctorius Sanctorius - Chronophysiology in the seventeenth century.

    Lemmer, Björn

    Chronobiology international

    2015  Volume 32, Issue 5, Page(s) 728–730

    MeSH term(s) Body Weight ; Chronotherapy/history ; Circadian Rhythm/physiology ; Heart Rate/physiology ; History, 17th Century ; Humans
    Language English
    Publishing date 2015-06
    Publishing country England
    Document type Historical Article ; Letter
    ZDB-ID 998996-1
    ISSN 1525-6073 ; 0742-0528
    ISSN (online) 1525-6073
    ISSN 0742-0528
    DOI 10.3109/07420528.2015.1027902
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Insufficient reply by Hermida et al. to the critical comments to the MAPEC and HYGIA studies.

    Lemmer, Björn / Middeke, Martin

    Chronobiology international

    2020  Volume 37, Issue 8, Page(s) 1269

    Abstract: The reply of Hermida et al. (2020) to our critical comments on the MAPEC and HYGIA Lemmer and ...

    Abstract The reply of Hermida et al. (2020) to our critical comments on the MAPEC and HYGIA Lemmer and Middeke (2020) studies in this Journal is insufficient and incomplete. Hermida does not address our first and main point on the baseline blood pressure values of 131/77 mmHg over 48 hours comprising 57.4% of the treated hypertensives (according to Table 1 in HYGIA) and consequently 42.6% of the untretated hypertensives! We criticized that in the HYGIA study; both normal and treated patients were included in one group not separated by statistics and without information on the baseline blood pressure values in each subgroup. This basic failure is our key issue of criticism and the basis of unreliability concerning the whole publication. This issue was not picked up in the recent comment of Hermida et al. (2020). They just concentrated on minor points in order to reject our severe criticism.
    MeSH term(s) Blood Pressure ; Chronotherapy ; Circadian Rhythm ; Humans ; Hypertension
    Language English
    Publishing date 2020-09-01
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 998996-1
    ISSN 1525-6073 ; 0742-0528
    ISSN (online) 1525-6073
    ISSN 0742-0528
    DOI 10.1080/07420528.2020.1812901
    Database MEDical Literature Analysis and Retrieval System OnLINE

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