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  1. Article: Emerging Role of m

    Sokpor, Godwin / Xie, Yuanbin / Nguyen, Huu P / Tuoc, Tran

    Frontiers in cell and developmental biology

    2021  Volume 9, Page(s) 656849

    Abstract: Dynamic modification of RNA affords proximal regulation of gene expression triggered by non-genomic or environmental changes. One such epitranscriptomic alteration in RNA metabolism is the installation of a methyl group on adenosine [ ... ...

    Abstract Dynamic modification of RNA affords proximal regulation of gene expression triggered by non-genomic or environmental changes. One such epitranscriptomic alteration in RNA metabolism is the installation of a methyl group on adenosine [N
    Language English
    Publishing date 2021-05-19
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2737824-X
    ISSN 2296-634X
    ISSN 2296-634X
    DOI 10.3389/fcell.2021.656849
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: GW190521: A Binary Black Hole Merger with a Total Mass of 150  M_{⊙}.

    Abbott, R / Abbott, T D / Abraham, S / Acernese, F / Ackley, K / Adams, C / Adhikari, R X / Adya, V B / Affeldt, C / Agathos, M / Agatsuma, K / Aggarwal, N / Aguiar, O D / Aich, A / Aiello, L / Ain, A / Ajith, P / Akcay, S / Allen, G /
    Allocca, A / Altin, P A / Amato, A / Anand, S / Ananyeva, A / Anderson, S B / Anderson, W G / Angelova, S V / Ansoldi, S / Antier, S / Appert, S / Arai, K / Araya, M C / Areeda, J S / Arène, M / Arnaud, N / Aronson, S M / Arun, K G / Asali, Y / Ascenzi, S / Ashton, G / Aston, S M / Astone, P / Aubin, F / Aufmuth, P / AultONeal, K / Austin, C / Avendano, V / Babak, S / Bacon, P / Badaracco, F / Bader, M K M / Bae, S / Baer, A M / Baird, J / Baldaccini, F / Ballardin, G / Ballmer, S W / Bals, A / Balsamo, A / Baltus, G / Banagiri, S / Bankar, D / Bankar, R S / Barayoga, J C / Barbieri, C / Barish, B C / Barker, D / Barkett, K / Barneo, P / Barone, F / Barr, B / Barsotti, L / Barsuglia, M / Barta, D / Bartlett, J / Bartos, I / Bassiri, R / Basti, A / Bawaj, M / Bayley, J C / Bazzan, M / Bécsy, B / Bejger, M / Belahcene, I / Bell, A S / Beniwal, D / Benjamin, M G / Bentley, J D / Bergamin, F / Berger, B K / Bergmann, G / Bernuzzi, S / Berry, C P L / Bersanetti, D / Bertolini, A / Betzwieser, J / Bhandare, R / Bhandari, A V / Bidler, J / Biggs, E / Bilenko, I A / Billingsley, G / Birney, R / Birnholtz, O / Biscans, S / Bischi, M / Biscoveanu, S / Bisht, A / Bissenbayeva, G / Bitossi, M / Bizouard, M A / Blackburn, J K / Blackman, J / Blair, C D / Blair, D G / Blair, R M / Bobba, F / Bode, N / Boer, M / Boetzel, Y / Bogaert, G / Bondu, F / Bonilla, E / Bonnand, R / Booker, P / Boom, B A / Bork, R / Boschi, V / Bose, S / Bossilkov, V / Bosveld, J / Bouffanais, Y / Bozzi, A / Bradaschia, C / Brady, P R / Bramley, A / Branchesi, M / Brau, J E / Breschi, M / Briant, T / Briggs, J H / Brighenti, F / Brillet, A / Brinkmann, M / Brockill, P / Brooks, A F / Brooks, J / Brown, D D / Brunett, S / Bruno, G / Bruntz, R / Buikema, A / Bulik, T / Bulten, H J / Buonanno, A / Buscicchio, R / Buskulic, D / Byer, R L / Cabero, M / Cadonati, L / Cagnoli, G / Cahillane, C / Calderón Bustillo, J / Callaghan, J D / Callister, T A / Calloni, E / Camp, J B / Canepa, M / Cannon, K C / Cao, H / Cao, J / Carapella, G / Carbognani, F / Caride, S / Carney, M F / Carullo, G / Casanueva Diaz, J / Casentini, C / Castañeda, J / Caudill, S / Cavaglià, M / Cavalier, F / Cavalieri, R / Cella, G / Cerdá-Durán, P / Cesarini, E / Chaibi, O / Chakravarti, K / Chan, C / Chan, M / Chandra, K / Chao, S / Charlton, P / Chase, E A / Chassande-Mottin, E / Chatterjee, D / Chaturvedi, M / Chatziioannou, K / Chen, H Y / Chen, X / Chen, Y / Cheng, H-P / Cheong, C K / Chia, H Y / Chiadini, F / Chierici, R / Chincarini, A / Chiummo, A / Cho, G / Cho, H S / Cho, M / Christensen, N / Chu, Q / Chua, S / Chung, K W / Chung, S / Ciani, G / Ciecielag, P / Cieślar, M / Ciobanu, A A / Ciolfi, R / Cipriano, F / Cirone, A / Clara, F / Clark, J A / Clearwater, P / Clesse, S / Cleva, F / Coccia, E / Cohadon, P-F / Cohen, D / Colleoni, M / Collette, C G / Collins, C / Colpi, M / Constancio, M / Conti, L / Cooper, S J / Corban, P / Corbitt, T R / Cordero-Carrión, I / Corezzi, S / Corley, K R / Cornish, N / Corre, D / Corsi, A / Cortese, S / Costa, C A / Cotesta, R / Coughlin, M W / Coughlin, S B / Coulon, J-P / Countryman, S T / Couvares, P / Covas, P B / Coward, D M / Cowart, M J / Coyne, D C / Coyne, R / Creighton, J D E / Creighton, T D / Cripe, J / Croquette, M / Crowder, S G / Cudell, J-R / Cullen, T J / Cumming, A / Cummings, R / Cunningham, L / Cuoco, E / Curylo, M / Canton, T Dal / Dálya, G / Dana, A / Daneshgaran-Bajastani, L M / D'Angelo, B / Danilishin, S L / D'Antonio, S / Danzmann, K / Darsow-Fromm, C / Dasgupta, A / Datrier, L E H / Dattilo, V / Dave, I / Davier, M / Davies, G S / Davis, D / Daw, E J / DeBra, D / Deenadayalan, M / Degallaix, J / De Laurentis, M / Deléglise, S / Delfavero, M / De Lillo, N / Del Pozzo, W / DeMarchi, L M / D'Emilio, V / Demos, N / Dent, T / De Pietri, R / De Rosa, R / De Rossi, C / DeSalvo, R / de Varona, O / Dhurandhar, S / Díaz, M C / Diaz-Ortiz, M / Dietrich, T / Di Fiore, L / Di Fronzo, C / Di Giorgio, C / Di Giovanni, F / Di Giovanni, M / Di Girolamo, T / Di Lieto, A / Ding, B / Di Pace, S / Di Palma, I / Di Renzo, F / Divakarla, A K / Dmitriev, A / Doctor, Z / Donovan, F / Dooley, K L / Doravari, S / Dorrington, I / Downes, T P / Drago, M / Driggers, J C / Du, Z / Ducoin, J-G / Dupej, P / Durante, O / D'Urso, D / Dwyer, S E / Easter, P J / Eddolls, G / Edelman, B / Edo, T B / Edy, O / Effler, A / Ehrens, P / Eichholz, J / Eikenberry, S S / Eisenmann, M / Eisenstein, R A / Ejlli, A / Errico, L / Essick, R C / Estelles, H / Estevez, D / Etienne, Z B / Etzel, T / Evans, M / Evans, T M / Ewing, B E / Fafone, V / Fairhurst, S / Fan, X / Farinon, S / Farr, B / Farr, W M / Fauchon-Jones, E J / Favata, M / Fays, M / Fazio, M / Feicht, J / Fejer, M M / Feng, F / Fenyvesi, E / Ferguson, D L / Fernandez-Galiana, A / Ferrante, I / Ferreira, E C / Ferreira, T A / Fidecaro, F / Fiori, I / Fiorucci, D / Fishbach, M / Fisher, R P / Fittipaldi, R / Fitz-Axen, M / Fiumara, V / Flaminio, R / Floden, E / Flynn, E / Fong, H / Font, J A / Forsyth, P W F / Fournier, J-D / Frasca, S / Frasconi, F / Frei, Z / Freise, A / Frey, R / Frey, V / Fritschel, P / Frolov, V V / Fronzè, G / Fulda, P / Fyffe, M / Gabbard, H A / Gadre, B U / Gaebel, S M / Gair, J R / Galaudage, S / Ganapathy, D / Ganguly, A / Gaonkar, S G / García-Quirós, C / Garufi, F / Gateley, B / Gaudio, S / Gayathri, V / Gemme, G / Genin, E / Gennai, A / George, D / George, J / Gergely, L / Ghonge, S / Ghosh, Abhirup / Ghosh, Archisman / Ghosh, S / Giacomazzo, B / Giaime, J A / Giardina, K D / Gibson, D R / Gier, C / Gill, K / Glanzer, J / Gniesmer, J / Godwin, P / Goetz, E / Goetz, R / Gohlke, N / Goncharov, B / González, G / Gopakumar, A / Gossan, S E / Gosselin, M / Gouaty, R / Grace, B / Grado, A / Granata, M / Grant, A / Gras, S / Grassia, P / Gray, C / Gray, R / Greco, G / Green, A C / Green, R / Gretarsson, E M / Griggs, H L / Grignani, G / Grimaldi, A / Grimm, S J / Grote, H / Grunewald, S / Gruning, P / Guidi, G M / Guimaraes, A R / Guixé, G / Gulati, H K / Guo, Y / Gupta, A / Gupta, Anchal / Gupta, P / Gustafson, E K / Gustafson, R / Haegel, L / Halim, O / Hall, E D / Hamilton, E Z / Hammond, G / Haney, M / Hanke, M M / Hanks, J / Hanna, C / Hannam, M D / Hannuksela, O A / Hansen, T J / Hanson, J / Harder, T / Hardwick, T / Haris, K / Harms, J / Harry, G M / Harry, I W / Hasskew, R K / Haster, C-J / Haughian, K / Hayes, F J / Healy, J / Heidmann, A / Heintze, M C / Heinze, J / Heitmann, H / Hellman, F / Hello, P / Hemming, G / Hendry, M / Heng, I S / Hennes, E / Hennig, J / Heurs, M / Hild, S / Hinderer, T / Hoback, S Y / Hochheim, S / Hofgard, E / Hofman, D / Holgado, A M / Holland, N A / Holt, K / Holz, D E / Hopkins, P / Horst, C / Hough, J / Howell, E J / Hoy, C G / Huang, Y / Hübner, M T / Huerta, E A / Huet, D / Hughey, B / Hui, V / Husa, S / Huttner, S H / Huxford, R / Huynh-Dinh, T / Idzkowski, B / Iess, A / Inchauspe, H / Ingram, C / Intini, G / Isac, J-M / Isi, M / Iyer, B R / Jacqmin, T / Jadhav, S J / Jadhav, S P / James, A L / Jani, K / Janthalur, N N / Jaranowski, P / Jariwala, D / Jaume, R / Jenkins, A C / Jiang, J / Johns, G R / Johnson-McDaniel, N K / Jones, A W / Jones, D I / Jones, J D / Jones, P / Jones, R / Jonker, R J G / Ju, L / Junker, J / Kalaghatgi, C V / Kalogera, V / Kamai, B / Kandhasamy, S / Kang, G / Kanner, J B / Kapadia, S J / Karki, S / Kashyap, R / Kasprzack, M / Kastaun, W / Katsanevas, S / Katsavounidis, E / Katzman, W / Kaufer, S / Kawabe, K / Kéfélian, F / Keitel, D / Keivani, A / Kennedy, R / Key, J S / Khadka, S / Khalili, F Y / Khan, I / Khan, S / Khan, Z A / Khazanov, E A / Khetan, N / Khursheed, M / Kijbunchoo, N / Kim, Chunglee / Kim, G J / Kim, J C / Kim, K / Kim, W / Kim, W S / Kim, Y-M / Kimball, C / King, P J / Kinley-Hanlon, M / Kirchhoff, R / Kissel, J S / Kleybolte, L / Klimenko, S / Knowles, T D / Knyazev, E / Koch, P / Koehlenbeck, S M / Koekoek, G / Koley, S / Kondrashov, V / Kontos, A / Koper, N / Korobko, M / Korth, W Z / Kovalam, M / Kozak, D B / Kringel, V / Krishnendu, N V / Królak, A / Krupinski, N / Kuehn, G / Kumar, A / Kumar, P / Kumar, Rahul / Kumar, Rakesh / Kumar, S / Kuo, L / Kutynia, A / Lackey, B D / Laghi, D / Lalande, E / Lam, T L / Lamberts, A / Landry, M / Lane, B B / Lang, R N / Lange, J / Lantz, B / Lanza, R K / La Rosa, I / Lartaux-Vollard, A / Lasky, P D / Laxen, M / Lazzarini, A / Lazzaro, C / Leaci, P / Leavey, S / Lecoeuche, Y K / Lee, C H / Lee, H M / Lee, H W / Lee, J / Lee, K / Lehmann, J / Leroy, N / Letendre, N / Levin, Y / Li, A K Y / Li, J / Li, K / Li, T G F / Li, X / Linde, F / Linker, S D / Linley, J N / Littenberg, T B / Liu, J / Liu, X / Llorens-Monteagudo, M / Lo, R K L / Lockwood, A / London, L T / Longo, A / Lorenzini, M / Loriette, V / Lormand, M / Losurdo, G / Lough, J D / Lousto, C O / Lovelace, G / Lück, H / Lumaca, D / Lundgren, A P / Ma, Y / Macas, R / Macfoy, S / MacInnis, M / Macleod, D M / MacMillan, I A O / Macquet, A / Magaña Hernandez, I / Magaña-Sandoval, F / Magee, R M / Majorana, E / Maksimovic, I / Malik, A / Man, N / Mandic, V / Mangano, V / Mansell, G L / Manske, M / Mantovani, M / Mapelli, M / Marchesoni, F / Marion, F / Márka, S / Márka, Z / Markakis, C / Markosyan, A S / Markowitz, A / Maros, E / Marquina, A / Marsat, S / Martelli, F / Martin, I W / Martin, R M / Martinez, V / Martynov, D V / Masalehdan, H / Mason, K / Massera, E / Masserot, A / Massinger, T J / Masso-Reid, M / Mastrogiovanni, S / Matas, A / Matichard, F / Mavalvala, N / Maynard, E / McCann, J J / McCarthy, R / McClelland, D E / McCormick, S / McCuller, L / McGuire, S C / McIsaac, C / McIver, J / McManus, D J / McRae, T / McWilliams, S T / Meacher, D / Meadors, G D / Mehmet, M / Mehta, A K / Mejuto Villa, E / Melatos, A / Mendell, G / Mercer, R A / Mereni, L / Merfeld, K / Merilh, E L / Merritt, J D / Merzougui, M / Meshkov, S / Messenger, C / Messick, C / Metzdorff, R / Meyers, P M / Meylahn, F / Mhaske, A / Miani, A / Miao, H / Michaloliakos, I / Michel, C / Middleton, H / Milano, L / Miller, A L / Millhouse, M / Mills, J C / Milotti, E / Milovich-Goff, M C / Minazzoli, O / Minenkov, Y / Mishkin, A / Mishra, C / Mistry, T / Mitra, S / Mitrofanov, V P / Mitselmakher, G / Mittleman, R / Mo, G / Mogushi, K / Mohapatra, S R P / Mohite, S R / Molina-Ruiz, M / Mondin, M / Montani, M / Moore, C J / Moraru, D / Morawski, F / Moreno, G / Morisaki, S / Mours, B / Mow-Lowry, C M / Mozzon, S / Muciaccia, F / Mukherjee, Arunava / Mukherjee, D / Mukherjee, S / Mukherjee, Subroto / Mukund, N / Mullavey, A / Munch, J / Muñiz, E A / Murray, P G / Nagar, A / Nardecchia, I / Naticchioni, L / Nayak, R K / Neil, B F / Neilson, J / Nelemans, G / Nelson, T J N / Nery, M / Neunzert, A / Ng, K Y / Ng, S / Nguyen, C / Nguyen, P / Nichols, D / Nichols, S A / Nissanke, S / Nitz, A / Nocera, F / Noh, M / North, C / Nothard, D / Nuttall, L K / Oberling, J / O'Brien, B D / Oganesyan, G / Ogin, G H / Oh, J J / Oh, S H / Ohme, F / Ohta, H / Okada, M A / Oliver, M / Olivetto, C / Oppermann, P / Oram, Richard J / O'Reilly, B / Ormiston, R G / Ortega, L F / O'Shaughnessy, R / Ossokine, S / Osthelder, C / Ottaway, D J / Overmier, H / Owen, B J / Pace, A E / Pagano, G / Page, M A / Pagliaroli, G / Pai, A / Pai, S A / Palamos, J R / Palashov, O / Palomba, C / Pan, H / Panda, P K / Pang, P T H / Pankow, C / Pannarale, F / Pant, B C / Paoletti, F / Paoli, A / Parida, A / Parker, W / Pascucci, D / Pasqualetti, A / Passaquieti, R / Passuello, D / Patricelli, B / Payne, E / Pearlstone, B L / Pechsiri, T C / Pedersen, A J / Pedraza, M / Pele, A / Penn, S / Perego, A / Perez, C J / Périgois, C / Perreca, A / Perriès, S / Petermann, J / Pfeiffer, H P / Phelps, M / Phukon, K S / Piccinni, O J / Pichot, M / Piendibene, M / Piergiovanni, F / Pierro, V / Pillant, G / Pinard, L / Pinto, I M / Piotrzkowski, K / Pirello, M / Pitkin, M / Plastino, W / Poggiani, R / Pong, D Y T / Ponrathnam, S / Popolizio, P / Porter, E K / Powell, J / Prajapati, A K / Prasai, K / Prasanna, R / Pratten, G / Prestegard, T / Principe, M / Prodi, G A / Prokhorov, L / Punturo, M / Puppo, P / Pürrer, M / Qi, H / Quetschke, V / Quinonez, P J / Raab, F J / Raaijmakers, G / Radkins, H / Radulesco, N / Raffai, P / Rafferty, H / Raja, S / Rajan, C / Rajbhandari, B / Rakhmanov, M / Ramirez, K E / Ramos-Buades, A / Rana, Javed / Rao, K / Rapagnani, P / Raymond, V / Razzano, M / Read, J / Regimbau, T / Rei, L / Reid, S / Reitze, D H / Rettegno, P / Ricci, F / Richardson, C J / Richardson, J W / Ricker, P M / Riemenschneider, G / Riles, K / Rizzo, M / Robertson, N A / Robinet, F / Rocchi, A / Rodriguez-Soto, R D / Rolland, L / Rollins, J G / Roma, V J / Romanelli, M / Romano, R / Romel, C L / Romero-Shaw, I M / Romie, J H / Rose, C A / Rose, D / Rose, K / Rosińska, D / Rosofsky, S G / Ross, M P / Rowan, S / Rowlinson, S J / Roy, P K / Roy, Santosh / Roy, Soumen / Ruggi, P / Rutins, G / Ryan, K / Sachdev, S / Sadecki, T / Sakellariadou, M / Salafia, O S / Salconi, L / Saleem, M / Salemi, F / Samajdar, A / Sanchez, E J / Sanchez, L E / Sanchis-Gual, N / Sanders, J R / Santiago, K A / Santos, E / Sarin, N / Sassolas, B / Sathyaprakash, B S / Sauter, O / Savage, R L / Savant, V / Sawant, D / Sayah, S / Schaetzl, D / Schale, P / Scheel, M / Scheuer, J / Schmidt, P / Schnabel, R / Schofield, R M S / Schönbeck, A / Schreiber, E / Schulte, B W / Schutz, B F / Schwarm, O / Schwartz, E / Scott, J / Scott, S M / Seidel, E / Sellers, D / Sengupta, A S / Sennett, N / Sentenac, D / Sequino, V / Sergeev, A / Setyawati, Y / Shaddock, D A / Shaffer, T / Sharifi, S / Shahriar, M S / Sharma, A / Sharma, P / Shawhan, P / Shen, H / Shikauchi, M / Shink, R / Shoemaker, D H / Shoemaker, D M / Shukla, K / ShyamSundar, S / Siellez, K / Sieniawska, M / Sigg, D / Singer, L P / Singh, D / Singh, N / Singha, A / Singhal, A / Sintes, A M / Sipala, V / Skliris, V / Slagmolen, B J J / Slaven-Blair, T J / Smetana, J / Smith, J R / Smith, R J E / Somala, S / Son, E J / Soni, S / Sorazu, B / Sordini, V / Sorrentino, F / Souradeep, T / Sowell, E / Spencer, A P / Spera, M / Srivastava, A K / Srivastava, V / Staats, K / Stachie, C / Standke, M / Steer, D A / Steinke, M / Steinlechner, J / Steinlechner, S / Steinmeyer, D / Stevenson, S / Stocks, D / Stops, D J / Stover, M / Strain, K A / Stratta, G / Strunk, A / Sturani, R / Stuver, A L / Sudhagar, S / Sudhir, V / Summerscales, T Z / Sun, L / Sunil, S / Sur, A / Suresh, J / Sutton, P J / Swinkels, B L / Szczepańczyk, M J / Tacca, M / Tait, S C / Talbot, C / Tanasijczuk, A J / Tanner, D B / Tao, D / Tápai, M / Tapia, A / Tapia San Martin, E N / Tasson, J D / Taylor, R / Tenorio, R / Terkowski, L / Thirugnanasambandam, M P / Thomas, M / Thomas, P / Thompson, J E / Thondapu, S R / Thorne, K A / Thrane, E / Tinsman, C L / Saravanan, T R / Tiwari, Shubhanshu / Tiwari, S / Tiwari, V / Toland, K / Tonelli, M / Tornasi, Z / Torres-Forné, A / Torrie, C I / Tosta E Melo, I / Töyrä, D / Travasso, F / Traylor, G / Tringali, M C / Tripathee, A / Trovato, A / Trudeau, R J / Tsang, K W / Tse, M / Tso, R / Tsukada, L / Tsuna, D / Tsutsui, T / Turconi, M / Ubhi, A S / Udall, R / Ueno, K / Ugolini, D / Unnikrishnan, C S / Urban, A L / Usman, S A / Utina, A C / Vahlbruch, H / Vajente, G / Valdes, G / Valentini, M / van Bakel, N / van Beuzekom, M / van den Brand, J F J / Van Den Broeck, C / Vander-Hyde, D C / van der Schaaf, L / Van Heijningen, J V / van Veggel, A A / Vardaro, M / Varma, V / Vass, S / Vasúth, M / Vecchio, A / Vedovato, G / Veitch, J / Veitch, P J / Venkateswara, K / Venugopalan, G / Verkindt, D / Veske, D / Vetrano, F / Viceré, A / Viets, A D / Vinciguerra, S / Vine, D J / Vinet, J-Y / Vitale, S / Vivanco, Francisco Hernandez / Vo, T / Vocca, H / Vorvick, C / Vyatchanin, S P / Wade, A R / Wade, L E / Wade, M / Walet, R / Walker, M / Wallace, G S / Wallace, L / Walsh, S / Wang, J Z / Wang, S / Wang, W H / Ward, R L / Warden, Z A / Warner, J / Was, M / Watchi, J / Weaver, B / Wei, L-W / Weinert, M / Weinstein, A J / Weiss, R / Wellmann, F / Wen, L / Weßels, P / Westhouse, J W / Wette, K / Whelan, J T / Whiting, B F / Whittle, C / Wilken, D M / Williams, D / Willis, J L / Willke, B / Winkler, W / Wipf, C C / Wittel, H / Woan, G / Woehler, J / Wofford, J K / Wong, I C F / Wright, J L / Wu, D S / Wysocki, D M / Xiao, L / Yamamoto, H / Yang, L / Yang, Y / Yang, Z / Yap, M J / Yazback, M / Yeeles, D W / Yu, Hang / Yu, Haocun / Yuen, S H R / Zadrożny, A K / Zadrożny, A / Zanolin, M / Zelenova, T / Zendri, J-P / Zevin, M / Zhang, J / Zhang, L / Zhang, T / Zhao, C / Zhao, G / Zhou, M / Zhou, Z / Zhu, X J / Zimmerman, A B / Zucker, M E / Zweizig, J

    Physical review letters

    2021  Volume 125, Issue 10, Page(s) 101102

    Abstract: ... with masses of 85_{-14}^{+21}  M_{⊙} and 66_{-18}^{+17}  M_{⊙} (90% credible intervals). We infer ... with only a 0.32% probability of being below 65  M_{⊙}. We calculate the mass of the remnant to be 142_{-16 ... 28}  M_{⊙}, which can be considered an intermediate mass black hole (IMBH). The luminosity distance ...

    Abstract On May 21, 2019 at 03:02:29 UTC Advanced LIGO and Advanced Virgo observed a short duration gravitational-wave signal, GW190521, with a three-detector network signal-to-noise ratio of 14.7, and an estimated false-alarm rate of 1 in 4900 yr using a search sensitive to generic transients. If GW190521 is from a quasicircular binary inspiral, then the detected signal is consistent with the merger of two black holes with masses of 85_{-14}^{+21}  M_{⊙} and 66_{-18}^{+17}  M_{⊙} (90% credible intervals). We infer that the primary black hole mass lies within the gap produced by (pulsational) pair-instability supernova processes, with only a 0.32% probability of being below 65  M_{⊙}. We calculate the mass of the remnant to be 142_{-16}^{+28}  M_{⊙}, which can be considered an intermediate mass black hole (IMBH). The luminosity distance of the source is 5.3_{-2.6}^{+2.4}  Gpc, corresponding to a redshift of 0.82_{-0.34}^{+0.28}. The inferred rate of mergers similar to GW190521 is 0.13_{-0.11}^{+0.30}  Gpc^{-3} yr^{-1}.
    Language English
    Publishing date 2021-02-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 208853-8
    ISSN 1079-7114 ; 0031-9007
    ISSN (online) 1079-7114
    ISSN 0031-9007
    DOI 10.1103/PhysRevLett.125.101102
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  3. Article ; Online: GW190814: Gravitational Waves from the Coalescence of a 23 M$_\odot$ Black Hole with a 2.6 M$_\odot$ Compact Object

    Collaboration, The LIGO Scientific / Abbott, the Virgo Collaboration R. / Abbott, T. D. / Abraham, S. / Acernese, F. / Ackley, K. / Adams, C. / Adhikari, R. X. / Adya, V. B. / Affeldt, C. / Agathos, M. / Agatsuma, K. / Aggarwal, N. / Aguiar, O. D. / Aich, A. / Aiello, L. / Ain, A. / Ajith, P. / Akcay, S. /
    Allen, G. / Allocca, A. / Altin, P. A. / Amato, A. / Anand, S. / Ananyeva, A. / Anderson, S. B. / Anderson, W. G. / Angelova, S. V. / Ansoldi, S. / Antier, S. / Appert, S. / Arai, K. / Araya, M. C. / Areeda, J. S. / Arene, M. / Arnaud, N. / Aronson, S. M. / Arun, K. G. / Asali, Y. / Ascenzi, S. / Ashton, G. / Aston, S. M. / Astone, P. / Aubin, F. / Aufmuth, P. / AultONeal, K. / Austin, C. / Avendano, V. / Babak, S. / Bacon, P. / Badaracco, F. / Bader, M. K. M. / Bae, S. / Baer, A. M. / Baird, J. / Baldaccini, F. / Ballardin, G. / Ballmer, S. W. / Bals, A. / Balsamo, A. / Baltus, G. / Banagiri, S. / Bankar, D. / Bankar, R. S. / Barayoga, J. C. / Barbieri, C. / Barish, B. C. / Barker, D. / Barkett, K. / Barneo, P. / Barone, F. / Barr, B. / Barsotti, L. / Barsuglia, M. / Barta, D. / Bartlett, J. / Bartos, I. / Bassiri, R. / Basti, A. / Bawaj, M. / Bayley, J. C. / Bazzan, M. / B'ecsy, B. / Bejger, M. / Belahcene, I. / Bell, A. S. / Beniwal, D. / Benjamin, M. G. / Benkel, R. / Bentley, J. D. / Bergamin, F. / Berger, B. K. / Bergmann, G. / Bernuzzi, S. / Berry, C. P. L. / Bersanetti, D. / Bertolini, A. / Betzwieser, J. / Bhandare, R. / Bhandari, A. V. / Bidler, J. / Biggs, E. / Bilenko, I. A. / Billingsley, G. / Birney, R. / Birnholtz, O. / Biscans, S. / Bischi, M. / Biscoveanu, S. / Bisht, A. / Bissenbayeva, G. / Bitossi, M. / Bizouard, M. A. / Blackburn, J. K. / Blackman, J. / Blair, C. D. / Blair, D. G. / Blair, R. M. / Bobba, F. / Bode, N. / Boer, M. / Boetzel, Y. / Bogaert, G. / Bondu, F. / Bonilla, E. / Bonnand, R. / Booker, P. / Boom, B. A. / Bork, R. / Boschi, V. / Bose, S. / Bossilkov, V. / Bosveld, J. / Bouffanais, Y. / Bozzi, A. / Bradaschia, C. / Brady, P. R. / Bramley, A. / Branchesi, M. / Brau, J. E. / Breschi, M. / Briant, T. / Briggs, J. H. / Brighenti, F. / Brillet, A. / Brinkmann, M. / Brito, R. / Brockill, P. / Brooks, A. F. / Brooks, J. / Brown, D. D. / Brunett, S. / Bruno, G. / Bruntz, R. / Buikema, A. / Bulik, T. / Bulten, H. J. / Buonanno, A. / Buskulic, D. / Byer, R. L. / Cabero, M. / Cadonati, L. / Cagnoli, G. / Cahillane, C. / Bustillo, J. Calder'on / Callaghan, J. D. / Callister, T. A. / Calloni, E. / Camp, J. B. / Canepa, M. / Cannon, K. C. / Cao, H. / Cao, J. / Carapella, G. / Carbognani, F. / Caride, S. / Carney, M. F. / Carullo, G. / Diaz, J. Casanueva / Casentini, C. / Castaneda, J. / Caudill, S. / Cavaglia, M. / Cavalier, F. / Cavalieri, R. / Cella, G. / Cerd'a-Dur'an, P. / Cesarini, E. / Chaibi, O. / Chakravarti, K. / Chan, C. / Chan, M. / Chao, S. / Charlton, P. / Chase, E. A. / Chassande-Mottin, E. / Chatterjee, D. / Chaturvedi, M. / Chatziioannou, K. / Chen, H. Y. / Chen, X. / Chen, Y. / Cheng, H.-P. / Cheong, C. K. / Chia, H. Y. / Chiadini, F. / Chierici, R. / Chincarini, A. / Chiummo, A. / Cho, G. / Cho, H. S. / Cho, M. / Christensen, N. / Chu, Q. / Chua, S. / Chung, K. W. / Chung, S. / Ciani, G. / Ciecielag, P. / Cie'slar, M. / Ciobanu, A. A. / Ciolfi, R. / Cipriano, F. / Cirone, A. / Clara, F. / Clark, J. A. / Clearwater, P. / Clesse, S. / Cleva, F. / Coccia, E. / Cohadon, P.-F. / Cohen, D. / Colleoni, M. / Collette, C. G. / Collins, C. / Colpi, M. / Constancio, M. / Conti, L. / Cooper, S. J. / Corban, P. / Corbitt, T. R. / Cordero-Carri'on, I. / Corezzi, S. / Corley, K. R. / Cornish, N. / Corre, D. / Corsi, A. / Cortese, S. / Costa, C. A. / Cotesta, R. / Coughlin, M. W. / Coughlin, S. B. / Coulon, J.-P. / Countryman, S. T. / Couvares, P. / Covas, P. B. / Coward, D. M. / Cowart, M. J. / Coyne, D. C. / Coyne, R. / Creighton, J. D. E. / Creighton, T. D. / Cripe, J. / Croquette, M. / Crowder, S. G. / Cudell, J.-R. / Cullen, T. J. / Cumming, A. / Cummings, R. / Cunningham, L. / Cuoco, E. / Curylo, M. / Canton, T. Dal / D'alya, G. / Dana, A. / Daneshgaran-Bajastani, L. M. / D'Angelo, B. / Danilishin, S. L. / D'Antonio, S. / Danzmann, K. / Darsow-Fromm, C. / Dasgupta, A. / Datrier, L. E. H. / Dattilo, V. / Dave, I. / Davier, M. / Davies, G. S. / Davis, D. / Daw, E. J. / DeBra, D. / Deenadayalan, M. / Degallaix, J. / Laurentis, M. De / Del'eglise, S. / Delfavero, M. / Lillo, N. De / Pozzo, W. Del / DeMarchi, L. M. / D'Emilio, V. / Demos, N. / Dent, T. / Pietri, R. De / Rosa, R. De / Rossi, C. De / DeSalvo, R. / Varona, O. de / Dhurandhar, S. / D'iaz, M. C. / Diaz-Ortiz, M. / Dietrich, T. / Fiore, L. Di / Fronzo, C. Di / Giorgio, C. Di / Giovanni, F. Di / Giovanni, M. Di / Girolamo, T. Di / Lieto, A. Di / Ding, B. / Pace, S. Di / Palma, I. Di / Renzo, F. Di / Divakarla, A. K. / Dmitriev, A. / Doctor, Z. / Donovan, F. / Dooley, K. L. / Doravari, S. / Dorrington, I. / Downes, T. P. / Drago, M. / Driggers, J. C. / Du, Z. / Ducoin, J.-G. / Dupej, P. / Durante, O. / D'Urso, D. / Dwyer, S. E. / Easter, P. J. / Eddolls, G. / Edelman, B. / Edo, T. B. / Edy, O. / Effler, A. / Ehrens, P. / Eichholz, J. / Eikenberry, S. S. / Eisenmann, M. / Eisenstein, R. A. / Ejlli, A. / Errico, L. / Essick, R. C. / Estelles, H. / Estevez, D. / Etienne, Z. B. / Etzel, T. / Evans, M. / Evans, T. M. / Ewing, B. E. / Fafone, V. / Fairhurst, S. / Fan, X. / Farinon, S. / Farr, B. / Farr, W. M. / Fauchon-Jones, E. J. / Favata, M. / Fays, M. / Fazio, M. / Feicht, J. / Fejer, M. M. / Feng, F. / Fenyvesi, E. / Ferguson, D. L. / Fernandez-Galiana, A. / Ferrante, I. / Ferreira, E. C. / Ferreira, T. A. / Fidecaro, F. / Fiori, I. / Fiorucci, D. / Fishbach, M. / Fisher, R. P. / Fittipaldi, R. / Fitz-Axen, M. / Fiumara, V. / Flaminio, R. / Floden, E. / Flynn, E. / Fong, H. / Font, J. A. / Forsyth, P. W. F. / Fournier, J.-D. / Frasca, S. / Frasconi, F. / Frei, Z. / Freise, A. / Frey, R. / Frey, V. / Fritschel, P. / Frolov, V. V. / Fronze, G. / Fulda, P. / Fyffe, M. / Gabbard, H. A. / Gadre, B. U. / Gaebel, S. M. / Gair, J. R. / Galaudage, S. / Ganapathy, D. / Ganguly, A. / Gaonkar, S. G. / Garc'ia-Quir'os, C. / Garufi, F. / Gateley, B. / Gaudio, S. / Gayathri, V. / Gemme, G. / Genin, E. / Gennai, A. / George, D. / George, J. / Gergely, L. / Ghonge, S. / Ghosh, Abhirup / Ghosh, Archisman / Ghosh, S. / Giacomazzo, B. / Giaime, J. A. / Giardina, K. D. / Gibson, D. R. / Gier, C. / Gill, K. / Glanzer, J. / Gniesmer, J. / Godwin, P. / Goetz, E. / Goetz, R. / Gohlke, N. / Goncharov, B. / Gonz'alez, G. / Gopakumar, A. / Gossan, S. E. / Gosselin, M. / Gouaty, R. / Grace, B. / Grado, A. / Granata, M. / Grant, A. / Gras, S. / Grassia, P. / Gray, C. / Gray, R. / Greco, G. / Green, A. C. / Green, R. / Gretarsson, E. M. / Griggs, H. L. / Grignani, G. / Grimaldi, A. / Grimm, S. J. / Grote, H. / Grunewald, S. / Gruning, P. / Guidi, G. M. / Guimaraes, A. R. / Guix'e, G. / Gulati, H. K. / Guo, Y. / Gupta, A. / Gupta, Anchal / Gupta, P. / Gustafson, E. K. / Gustafson, R. / Haegel, L. / Halim, O. / Hall, E. D. / Hamilton, E. Z. / Hammond, G. / Haney, M. / Hanke, M. M. / Hanks, J. / Hanna, C. / Hannam, M. D. / Hannuksela, O. A. / Hansen, T. J. / Hanson, J. / Harder, T. / Hardwick, T. / Haris, K. / Harms, J. / Harry, G. M. / Harry, I. W. / Hasskew, R. K. / Haster, C.-J. / Haughian, K. / Hayes, F. J. / Healy, J. / Heidmann, A. / Heintze, M. C. / Heinze, J. / Heitmann, H. / Hellman, F. / Hello, P. / Hemming, G. / Hendry, M. / Heng, I. S. / Hennes, E. / Hennig, J. / Heurs, M. / Hild, S. / Hinderer, T. / Hoback, S. Y. / Hochheim, S. / Hofgard, E. / Hofman, D. / Holgado, A. M. / Holland, N. A. / Holt, K. / Holz, D. E. / Hopkins, P. / Horst, C. / Hough, J. / Howell, E. J. / Hoy, C. G. / Huang, Y. / Hubner, M. T. / Huerta, E. A. / Huet, D. / Hughey, B. / Hui, V. / Husa, S. / Huttner, S. H. / Huxford, R. / Huynh-Dinh, T. / Idzkowski, B. / Iess, A. / Inchauspe, H. / Ingram, C. / Intini, G. / Isac, J.-M. / Isi, M. / Iyer, B. R. / Jacqmin, T. / Jadhav, S. J. / Jadhav, S. P. / James, A. L. / Jani, K. / Janthalur, N. N. / Jaranowski, P. / Jariwala, D. / Jaume, R. / Jenkins, A. C. / Jiang, J. / Johns, G. R. / Johnson-McDaniel, N. K. / Jones, A. W. / Jones, D. I. / Jones, J. D. / Jones, P. / Jones, R. / Jonker, R. J. G. / Ju, L. / Junker, J. / Kalaghatgi, C. V. / Kalogera, V. / Kamai, B. / Kandhasamy, S. / Kang, G. / Kanner, J. B. / Kapadia, S. J. / Karki, S. / Kashyap, R. / Kasprzack, M. / Kastaun, W. / Katsanevas, S. / Katsavounidis, E. / Katzman, W. / Kaufer, S. / Kawabe, K. / K'ef'elian, F. / Keitel, D. / Keivani, A. / Kennedy, R. / Key, J. S. / Khadka, S. / Khalili, F. Y. / Khan, I. / Khan, S. / Khan, Z. A. / Khazanov, E. A. / Khetan, N. / Khursheed, M. / Kijbunchoo, N. / Kim, Chunglee / Kim, G. J. / Kim, J. C. / Kim, K. / Kim, W. / Kim, W. S. / Kim, Y.-M. / Kimball, C. / King, P. J. / Kinley-Hanlon, M. / Kirchhoff, R. / Kissel, J. S. / Kleybolte, L. / Klimenko, S. / Knowles, T. D. / Knyazev, E. / Koch, P. / Koehlenbeck, S. M. / Koekoek, G. / Koley, S. / Kondrashov, V. / Kontos, A. / Koper, N. / Korobko, M. / Korth, W. Z. / Kovalam, M. / Kozak, D. B. / Kringel, V. / Krishnendu, N. V. / Kr'olak, A. / Krupinski, N. / Kuehn, G. / Kumar, A. / Kumar, P. / Kumar, Rahul / Kumar, Rakesh / Kumar, S. / Kuo, L. / Kutynia, A. / Lackey, B. D. / Laghi, D. / Lalande, E. / Lam, T. L. / Lamberts, A. / Landry, M. / Landry, P. / Lane, B. B. / Lang, R. N. / Lange, J. / Lantz, B. / Lanza, R. K. / Rosa, I. La / Lartaux-Vollard, A. / Lasky, P. D. / Laxen, M. / Lazzarini, A. / Lazzaro, C. / Leaci, P. / Leavey, S. / Lecoeuche, Y. K. / Lee, C. H. / Lee, H. M. / Lee, H. W. / Lee, J. / Lee, K. / Lehmann, J. / Leroy, N. / Letendre, N. / Levin, Y. / Li, A. K. Y. / Li, J. / li, K. / Li, T. G. F. / Li, X. / Linde, F. / Linker, S. D. / Linley, J. N. / Littenberg, T. B. / Liu, J. / Liu, X. / Llorens-Monteagudo, M. / Lo, R. K. L. / Lockwood, A. / London, L. 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E. / Sanchis-Gual, N. / Sanders, J. R. / Santiago, K. A. / Santos, E. / Sarin, N. / Sassolas, B. / Sathyaprakash, B. S. / Sauter, O. / Savage, R. L. / Savant, V. / Sawant, D. / Sayah, S. / Schaetzl, D. / Schale, P. / Scheel, M. / Scheuer, J. / Schmidt, P. / Schnabel, R. / Schofield, R. M. S. / Schonbeck, A. / Schreiber, E. / Schulte, B. W. / Schutz, B. F. / Schwarm, O. / Schwartz, E. / Scott, J. / Scott, S. M. / Seidel, E. / Sellers, D. / Sengupta, A. S. / Sennett, N. / Sentenac, D. / Sequino, V. / Sergeev, A. / Setyawati, Y. / Shaddock, D. A. / Shaffer, T. / Shahriar, M. S. / Sharma, A. / Sharma, P. / Shawhan, P. / Shen, H. / Shikauchi, M. / Shink, R. / Shoemaker, D. H. / Shoemaker, D. M. / Shukla, K. / ShyamSundar, S. / Siellez, K. / Sieniawska, M. / Sigg, D. / Singer, L. P. / Singh, D. / Singh, N. / Singha, A. / Singhal, A. / Sintes, A. M. / Sipala, V. / Skliris, V. / Slagmolen, B. J. J. / Slaven-Blair, T. J. / Smetana, J. / Smith, J. R. / Smith, R. J. E. / Somala, S. / Son, E. J. / Soni, S. / Sorazu, B. / Sordini, V. / Sorrentino, F. / Souradeep, T. / Sowell, E. / Spencer, A. P. / Spera, M. / Srivastava, A. K. / Srivastava, V. / Staats, K. / Stachie, C. / Standke, M. / Steer, D. A. / Steinhoff, J. / Steinke, M. / Steinlechner, J. / Steinlechner, S. / Steinmeyer, D. / Stevenson, S. / Stocks, D. / Stops, D. J. / Stover, M. / Strain, K. A. / Stratta, G. / Strunk, A. / Sturani, R. / Stuver, A. L. / Sudhagar, S. / Sudhir, V. / Summerscales, T. Z. / Sun, L. / Sunil, S. / Sur, A. / Suresh, J. / Sutton, P. J. / Swinkels, B. L. / Szczepa'nczyk, M. J. / Tacca, M. / Tait, S. C. / Talbot, C. / Tanasijczuk, A. J. / Tanner, D. B. / Tao, D. / T'apai, M. / Tapia, A. / Martin, E. N. Tapia San / Tasson, J. D. / Taylor, R. / Tenorio, R. / Terkowski, L. / Thirugnanasambandam, M. P. / Thomas, M. / Thomas, P. / Thompson, J. E. / Thondapu, S. R. / Thorne, K. A. / Thrane, E. / Tinsman, C. L. / Saravanan, T. R. / Tiwari, Shubhanshu / Tiwari, S. / Tiwari, V. / Toland, K. / Tonelli, M. / Tornasi, Z. / Torres-Forn'e, A. / Torrie, C. I. / Melo, I. Tosta e / Toyra, D. / Trail, E. A. / Travasso, F. / Traylor, G. / Tringali, M. C. / Tripathee, A. / Trovato, A. / Trudeau, R. J. / Tsang, K. W. / Tse, M. / Tso, R. / Tsukada, L. / Tsuna, D. / Tsutsui, T. / Turconi, M. / Ubhi, A. S. / Ueno, K. / Ugolini, D. / Unnikrishnan, C. S. / Urban, A. L. / Usman, S. A. / Utina, A. C. / Vahlbruch, H. / Vajente, G. / Valdes, G. / Valentini, M. / Bakel, N. van / Beuzekom, M. van / Brand, J. F. J. van den / Broeck, C. Van Den / Vander-Hyde, D. C. / Schaaf, L. van der / Heijningen, J. V. Van / Veggel, A. A. van / Vardaro, M. / Varma, V. / Vass, S. / Vas'uth, M. / Vecchio, A. / Vedovato, G. / Veitch, J. / Veitch, P. J. / Venkateswara, K. / Venugopalan, G. / Verkindt, D. / Veske, D. / Vetrano, F. / Vicer'e, A. / Viets, A. D. / Vinciguerra, S. / Vine, D. J. / Vinet, J.-Y. / Vitale, S. / Vivanco, Francisco Hernandez / Vo, T. / Vocca, H. / Vorvick, C. / Vyatchanin, S. P. / Wade, A. R. / Wade, L. E. / Wade, M. / Walet, R. / Walker, M. / Wallace, G. S. / Wallace, L. / Walsh, S. / Wang, J. Z. / Wang, S. / Wang, W. H. / Ward, R. L. / Warden, Z. A. / Warner, J. / Was, M. / Watchi, J. / Weaver, B. / Wei, L.-W. / Weinert, M. / Weinstein, A. J. / Weiss, R. / Wellmann, F. / Wen, L. / Wessels, P. / Westhouse, J. W. / Wette, K. / Whelan, J. T. / Whiting, B. F. / Whittle, C. / Wilken, D. M. / Williams, D. / Willis, J. L. / Willke, B. / Winkler, W. / Wipf, C. C. / Wittel, H. / Woan, G. / Woehler, J. / Wofford, J. K. / Wong, C. / Wright, J. L. / Wu, D. S. / Wysocki, D. M. / Xiao, L. / Yamamoto, H. / Yang, L. / Yang, Y. / Yang, Z. / Yap, M. J. / Yazback, M. / Yeeles, D. W. / Yu, Hang / Yu, Haocun / Yuen, S. H. R. / Zadro.zny, A. K. / Zadro.zny, A. / Zanolin, M. / Zelenova, T. / Zendri, J.-P. / Zevin, M. / Zhang, J. / Zhang, L. / Zhang, T. / Zhao, C. / Zhao, G. / Zhou, M. / Zhou, Z. / Zhu, X. J. / Zimmerman, A. B. / Zucker, M. E. / Zweizig, J.

    Abstract: We report the observation of a compact binary coalescence involving a 22.2 - 24.3 $M_{\odot}$ black ... hole and a compact object with a mass of 2.50 - 2.67 $M_{\odot}$ (all measurements quoted at the 90$ ...

    Abstract We report the observation of a compact binary coalescence involving a 22.2 - 24.3 $M_{\odot}$ black hole and a compact object with a mass of 2.50 - 2.67 $M_{\odot}$ (all measurements quoted at the 90$\%$ credible level). The gravitational-wave signal, GW190814, was observed during LIGO's and Virgo's third observing run on August 14, 2019 at 21:10:39 UTC and has a signal-to-noise ratio of 25 in the three-detector network. The source was localized to 18.5 deg$^2$ at a distance of $241^{+41}_{-45}$ Mpc; no electromagnetic counterpart has been confirmed to date. The source has the most unequal mass ratio yet measured with gravitational waves, $0.112^{+0.008}_{-0.009}$, and its secondary component is either the lightest black hole or the heaviest neutron star ever discovered in a double compact-object system. The dimensionless spin of the primary black hole is tightly constrained to $\leq 0.07$. Tests of general relativity reveal no measurable deviations from the theory, and its prediction of higher-multipole emission is confirmed at high confidence. We estimate a merger rate density of 1-23 Gpc$^{-3}$ yr$^{-1}$ for the new class of binary coalescence sources that GW190814 represents. Astrophysical models predict that binaries with mass ratios similar to this event can form through several channels, but are unlikely to have formed in globular clusters. However, the combination of mass ratio, component masses, and the inferred merger rate for this event challenges all current models for the formation and mass distribution of compact-object binaries.
    Keywords covid19
    Publisher ArXiv
    Document type Article ; Online
    DOI 10.3847/2041-8213/ab960f
    Database COVID19

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  4. Article: Phase 1/2 Trial of CLAG-M with Dose-Escalated Mitoxantrone in Combination with Fractionated-Dose Gemtuzumab Ozogamicin for Newly Diagnosed Acute Myeloid Leukemia and Other High-Grade Myeloid Neoplasms.

    Godwin, Colin D / Rodríguez-Arbolí, Eduardo / Othus, Megan / Halpern, Anna B / Appelbaum, Jacob S / Percival, Mary-Elizabeth M / Hendrie, Paul C / Oehler, Vivian G / Keel, Siobán B / Abkowitz, Janis L / Cooper, Jason P / Cassaday, Ryan D / Estey, Elihu H / Walter, Roland B

    Cancers

    2022  Volume 14, Issue 12

    Abstract: ... high-dose cytarabine, G-CSF, and dose-escalated mitoxantrone (CLAG-M) in adults with newly diagnosed ... dose of GO or three doses of GO (GO3) at 3 mg/m ...

    Abstract Gemtuzumab ozogamicin (GO) improves outcomes when added to intensive AML chemotherapy. A meta-analysis suggested the greatest benefit when combining fractionated doses of GO (GO3) with 7 + 3. To test whether GO3 can be safely used with high intensity chemotherapy, we conducted a phase 1/2 study of cladribine, high-dose cytarabine, G-CSF, and dose-escalated mitoxantrone (CLAG-M) in adults with newly diagnosed AML or other high-grade myeloid neoplasm (NCT03531918). Sixty-six patients with a median age of 65 (range: 19-80) years were enrolled. Cohorts of six and twelve patients were treated in phase 1 with one dose of GO or three doses of GO (GO3) at 3 mg/m
    Language English
    Publishing date 2022-06-14
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527080-1
    ISSN 2072-6694
    ISSN 2072-6694
    DOI 10.3390/cancers14122934
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  5. Article ; Online: In Vitro Anti-Venom Potentials of Aqueous Extract and Oils of Toona ciliata M. Roem against Cobra Venom and Chemical Constituents of Oils

    David Fred Okot / Jane Namukobe / Patrick Vudriko / Godwin Anywar / Matthias Heydenreich / Oyedeji Adebola Omowumi / Robert Byamukama

    Molecules, Vol 28, Iss 3089, p

    2023  Volume 3089

    Abstract: There are high mortality and morbidity rates from poisonous snakebites globally. Many medicinal plants are locally used for snakebite treatment in Uganda. This study aimed to determine the in vitro anti-venom activities of aqueous extract and oils of ... ...

    Abstract There are high mortality and morbidity rates from poisonous snakebites globally. Many medicinal plants are locally used for snakebite treatment in Uganda. This study aimed to determine the in vitro anti-venom activities of aqueous extract and oils of Toona ciliata against Naja melanoleuca venom. A mixture of venom and extract was administered intramuscularly in rats. Anticoagulant, antiphospholipase A 2 (PLA 2 ) inhibition assay, and gel electrophoresis for anti-venom activities of oils were done. The chemical constituents of the oils of ciliata were identified using Gas chromatography-tandem mass spectroscopy (GC-MS/MS). The LD 50 of the venom was 0.168 ± 0.21 µg/g. The venom and aqueous extract mixture (1.25 µg/g and 3.5 mg/g) did not cause any rat mortality, while the control with venom only (1.25 µg/g) caused death in 1 h. The aqueous extract of T. ciliata inhibited the anticoagulation activity of N. melanoleuca venom from 18.58 min. to 4.83 min and reduced the hemolytic halo diameter from 24 to 22 mm. SDS-PAGE gel electrophoresis showed that oils completely cleared venom proteins. GC-MS/MS analysis showed that the oils had sesquiterpene hydrocarbons (60%) in the volatile oil (VO) and oxygenated sesquiterpenes (48.89%) in the non-volatile oils (NVO). Some major compounds reported for the first time in T. ciliata NVOs were: Rutamarin (52.55%), β-Himachalol (9.53%), Girinimbine (6.68%) and Oprea1 (6.24%). Most compounds in the VO were reported for the first time in T. ciliata, including the major ones Santalene (8.55%) and Himachal-7-ol (6.69%). The result showed that aqueous extract and oils of T. ciliata have anti-venom/procoagulant activities and completely neutralized the venom. We recommend a study on isolation and testing the pure compounds against the same venom.
    Keywords snakebite ; venom ; medicinal plants ; anticoagulation ; antiphospholipase a 2 inhibitor ; rutamarin and seselin ; Organic chemistry ; QD241-441
    Subject code 616
    Language English
    Publishing date 2023-03-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
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  6. Article ; Online: Nephrology Policy: Kidney Transplantation.

    Godwin, Miriam

    Advances in chronic kidney disease

    2022  Volume 29, Issue 1, Page(s) 59–64

    Abstract: Kidney transplant policy has not historically been considered a domain of nephrology policy; despite that, the US transplant system is marked by missed opportunities that prevent patients from accessing a kidney transplant. Policymakers in the federal ... ...

    Abstract Kidney transplant policy has not historically been considered a domain of nephrology policy; despite that, the US transplant system is marked by missed opportunities that prevent patients from accessing a kidney transplant. Policymakers in the federal government are focused on growing the inadequate supply of kidneys, especially on increasing procurement of deceased donor organs, and reducing kidney discards. There are many more challenges in transplantation that require the attention of experts in nephrology policy, whether in the Administration, Congress, advocacy organizations, or clinical practice. Thoughtful policy solutions are needed to improve transplant equity, balance competing patient desires, increase living donation, develop and implement measures of transplant center performance, and create an infrastructure for the long-term management of transplant recipients.
    MeSH term(s) Humans ; Kidney ; Kidney Transplantation ; Nephrology ; Policy ; Tissue and Organ Procurement ; Transplant Recipients
    Language English
    Publishing date 2022-06-09
    Publishing country United States
    Document type Journal Article ; Review
    ISSN 1548-5609 ; 1548-5595
    ISSN (online) 1548-5609
    ISSN 1548-5595
    DOI 10.1053/j.ackd.2022.02.007
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  7. Article ; Online: Advocating for Health Equity in Kidney Care: An Urgent Need.

    Godwin, Miriam

    Kidney medicine

    2021  Volume 3, Issue 6, Page(s) 1082–1085

    Language English
    Publishing date 2021-09-03
    Publishing country United States
    Document type Journal Article
    ISSN 2590-0595
    ISSN (online) 2590-0595
    DOI 10.1016/j.xkme.2021.05.012
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  8. Article: Staatsinszenierung, Erinnerungsmarathon und Volksfest, Afrika feiert 50 Jahre Unabhängigkeit, hrsg. von Lentz Carola und Godwin Kornes : Frankfurt a. M., Brandes & Apsel, 2011 / [rezensiert von:] Erika Dahlmanns

    Dahlmanns, Erika / Kornes, Godwin / Lentz, Carola

    Sociologus Vol. 62, No. 1 , p. 109-112

    2012  Volume 62, Issue 1, Page(s) 109–112

    Language German
    Publisher Duncker & Humblot
    Publishing place Berlin
    Document type Article
    ZDB-ID 4842-2
    ISSN 0038-0377
    Database Former special subject collection: coastal and deep sea fishing

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  9. Article ; Online: Consideration of Climate Change on Environmental Impact Assessment in Tanzania: Challenges and Prospects.

    Pauline, Noah M / Lema, Godwin A

    Environmental management

    2024  

    Abstract: The potential of the environmental impact assessment (EIA) process to respond to climate change impacts of development projects can only be realized with the support of policies, regulations, and actors' engagement. While considering climate change in ... ...

    Abstract The potential of the environmental impact assessment (EIA) process to respond to climate change impacts of development projects can only be realized with the support of policies, regulations, and actors' engagement. While considering climate change in EIA has become partly mandatory through the EU revised Directive in Europe, African countries are still lagging. This paper assesses Tanzanian policies, laws, regulations, and EIA reports to uncover consideration of climate change impacts, adaptation, and mitigation measures, drawing from the transformational role of EIA. The methodology integrates content analysis, interpretive policy analysis, and discourse analysis. The analyses draw from environmental policy, three regulatory documents and three EIA reports in Tanzania using a multi-cases study design. The aim was to understand how considering Climate Change issues in EIA has played out in practice. Results reveal less consideration of climate change issues in EIA. The policy, laws, and regulations do not guide when and how the EIA process should consider climate change-related impacts mitigation and adaptation. The practice of EIA in the country is utterly procedural in line with regulations provisions. Consequently, environmental impact statements only profile the climatology of the study area without conducting a deeper analysis of the historical and future climate to enhance the resilience of proposed projects. The weakness exposed in the laws and regulations contributes to the challenges of responding to the impacts of climate change through the EIA process. It is possible to address climate change issues throughout the project life cycle, including design, approval, implementation, monitoring, and auditing, provided the policy and regulations guide how and when the EIA process should consider climate change issues. Additionally, increasing stakeholders' awareness and participation can enhance the EIA process's potential to respond to the impacts of climate change.
    Language English
    Publishing date 2024-04-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1478932-2
    ISSN 1432-1009 ; 0364-152X
    ISSN (online) 1432-1009
    ISSN 0364-152X
    DOI 10.1007/s00267-024-01972-8
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  10. Article ; Online: The effect of single versus dual nutrient decreases on phytoplankton growth rates, community composition, and Microcystin concentration in the western basin of Lake Erie.

    Baer, Mikayla M / Godwin, Casey M / Johengen, Thomas H

    Harmful algae

    2023  Volume 123, Page(s) 102382

    Abstract: The primary management strategy for minimizing harmful algal blooms (HABs) in Lake Erie has been to reduce springtime loading of phosphorus (P) to the lake. However, some studies have shown that the growth rate and toxin content for the HABs-causing ... ...

    Abstract The primary management strategy for minimizing harmful algal blooms (HABs) in Lake Erie has been to reduce springtime loading of phosphorus (P) to the lake. However, some studies have shown that the growth rate and toxin content for the HABs-causing cyanobacterium Microcystis also respond to the availability of dissolved inorganic nitrogen (N). This evidence is based on both observational studies that correlate bloom development with changes in N forms and concentrations in the lake, and experiments in which P and/or N are added at concentrations in excess of those present in the lake. The goal of this study was to determine whether a combined decrease in N and P concentrations from ambient levels in Lake Erie could limit the development of HABs more than a reduction in P concentration only. To directly test the impact of P-only versus dual N and P concentration decreases on phytoplankton in the western basin of Lake Erie, we evaluated changes in growth rate, community composition, and microcystin (MC) concentration through eight bioassay experiments performed from June through October 2018, which encompassed the normal Lake Erie Microcystis-dominated HAB season. Our results showed that during the first five experiments covering June 25 to August 13, the P-only and the dual N and P decrease treatments had similar effects. However, when ambient N became scarce later in the season, the N and P decrease treatments resulted in negative growth rates for cyanobacteria, whereas -P only decreases did not. During low ambient N conditions, dual nutrient decreases lowered the prevalence of cyanobacteria among the total phytoplankton community and decreased microcystin concentrations. The results presented here complement previous experimental work on Lake Erie and suggest that dual nutrient control could be an effective management strategy to decrease microcystin production during the bloom and even possibly diminish or shorten the duration of the bloom based on creating nutrient limiting conditions sooner in the HAB growing season.
    MeSH term(s) Phytoplankton ; Lakes/microbiology ; Microcystins ; Cyanobacteria ; Microcystis
    Chemical Substances Microcystins
    Language English
    Publishing date 2023-01-17
    Publishing country Netherlands
    Document type Journal Article ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 2091119-1
    ISSN 1878-1470 ; 1568-9883
    ISSN (online) 1878-1470
    ISSN 1568-9883
    DOI 10.1016/j.hal.2023.102382
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    Z 7473: Show issues

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