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  1. Book: Wu dai shi guo song liao xia jin

    Liu, Zhanwu / Yin, Jingfang / Deng, Rui

    (Zhong guo li shi da shi bian nian : 中国历史大事编年 ; / Zhang xi kong, tian jue zhu bian ; 3)

    1989  

    Author's details Liu zhan wu, yin jing fang, deng rui bian zhu
    Series title Zhong guo li shi da shi bian nian : 中国历史大事编年
    / Zhang xi kong, tian jue zhu bian ; 3
    Language Chinese
    Dates of publication 1989-1987
    Size 4, 695 S
    Edition Di 1 ban
    Publisher Bei jing chu ban she
    Publishing place Bei jing
    Document type Book
    ISBN 7200002976 ; 9787200002973
    Database Former special subject collection: coastal and deep sea fishing

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  2. Article ; Online: A novel TOX3-WDR5-ABCG2 signaling axis regulates the progression of colorectal cancer by accelerating stem-like traits and chemoresistance.

    Hao, Jiaojiao / Huang, Jinsheng / Hua, Chunyu / Zuo, Yan / Yu, Wendan / Wu, Xiaojun / Li, Liren / Xue, Guoqing / Wan, Xinyu / Ru, Liyuan / Guo, Ziyue / Han, Shilong / Deng, Wuguo / Lin, Fei / Guo, Wei

    PLoS biology

    2023  Volume 21, Issue 9, Page(s) e3002256

    Abstract: The eradication of cancer stem cells (CSCs) with drug resistance confers the probability of local tumor control after chemotherapy or targeted therapy. As the main drug resistance marker, ABCG2 is also critical for colorectal cancer (CRC) evolution, in ... ...

    Abstract The eradication of cancer stem cells (CSCs) with drug resistance confers the probability of local tumor control after chemotherapy or targeted therapy. As the main drug resistance marker, ABCG2 is also critical for colorectal cancer (CRC) evolution, in particular cancer stem-like traits expansion. Hitherto, the knowledge about the expression regulation of ABCG2, in particular its upstream transcriptional regulatory mechanisms, remains limited in cancer, including CRC. Here, ABCG2 was found to be markedly up-regulated in CRC CSCs (cCSCs) expansion and chemo-resistant CRC tissues and closely associated with CRC recurrence. Mechanistically, TOX3 was identified as a specific transcriptional factor to drive ABCG2 expression and subsequent cCSCs expansion and chemoresistance by binding to -261 to -141 segments of the ABCG2 promoter region. Moreover, we found that TOX3 recruited WDR5 to promote tri-methylation of H3K4 at the ABCG2 promoter in cCSCs, which further confers stem-like traits and chemoresistance to CRC by co-regulating the transcription of ABCG2. In line with this observation, TOX3, WDR5, and ABCG2 showed abnormal activation in chemo-resistant tumor tissues of in situ CRC mouse model and clinical investigation further demonstrated the comprehensive assessment of TOX3, WDR5, and ABCG2 could be a more efficient strategy for survival prediction of CRC patients with recurrence or metastasis. Thus, our study found that TOX3-WDR5/ABCG2 signaling axis plays a critical role in regulating CRC stem-like traits and chemoresistance, and a combination of chemotherapy with WDR5 inhibitors may induce synthetic lethality in ABCG2-deregulated tumors.
    MeSH term(s) Animals ; Mice ; Drug Resistance, Neoplasm/genetics ; Disease Models, Animal ; Knowledge ; Neoplastic Stem Cells ; Colorectal Neoplasms/drug therapy ; Colorectal Neoplasms/genetics
    Language English
    Publishing date 2023-09-14
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2126776-5
    ISSN 1545-7885 ; 1544-9173
    ISSN (online) 1545-7885
    ISSN 1544-9173
    DOI 10.1371/journal.pbio.3002256
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6193: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  3. Article ; Online: Core-Hole Excitation Spectra of the Oxides and Hydrates of Fullerene C

    Li, Xiong / Wang, Shuyi / Guo, Jingdong / Wu, Ziye / Guo, Changrui / Cai, Shaohong / Deng, Mingsen

    Molecules (Basel, Switzerland)

    2024  Volume 29, Issue 3

    Abstract: The interaction of fullerenes and their derivatives with environmental molecules such as oxygen or water was crucial for the rational design of low-dimensional materials and devices. In this paper, the near-edge X-ray absorption fine structure (NEXAFS), ... ...

    Abstract The interaction of fullerenes and their derivatives with environmental molecules such as oxygen or water was crucial for the rational design of low-dimensional materials and devices. In this paper, the near-edge X-ray absorption fine structure (NEXAFS), X-ray emission spectroscopy (XES) and X-ray photoelectron spectroscopy (XPS) shake-up satellites were employed to distinguish the oxides and hydrates of the fullerene C
    Language English
    Publishing date 2024-01-26
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules29030609
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.MO 81: Show issues

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  4. Article ; Online: Oxygen Vacancies Driven by Co in the Deeply Charged State Inducing Intragranular Cracking of Ni-Rich Cathodes.

    Guo, Fuqiren / Chen, Yaoqu / Song, Yang / Deng, Yuting / Hua, Weibo / Yang, Wen / Chen, Ting / Wu, Zhenguo / Qiu, Lang / Guo, Xiaodong

    Small (Weinheim an der Bergstrasse, Germany)

    2024  , Page(s) e2310321

    Abstract: Intragranular cracking within the material structure of Ni-rich ( ... ...

    Abstract Intragranular cracking within the material structure of Ni-rich (LiNi
    Language English
    Publishing date 2024-01-05
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2168935-0
    ISSN 1613-6829 ; 1613-6810
    ISSN (online) 1613-6829
    ISSN 1613-6810
    DOI 10.1002/smll.202310321
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Smart Wearable Systems for Health Monitoring.

    Deng, Zhiyong / Guo, Lihao / Chen, Ximeng / Wu, Weiwei

    Sensors (Basel, Switzerland)

    2023  Volume 23, Issue 5

    Abstract: Smart wearable systems for health monitoring are highly desired in personal wisdom medicine and telemedicine. These systems make the detecting, monitoring, and recording of biosignals portable, long-term, and comfortable. The development and optimization ...

    Abstract Smart wearable systems for health monitoring are highly desired in personal wisdom medicine and telemedicine. These systems make the detecting, monitoring, and recording of biosignals portable, long-term, and comfortable. The development and optimization of wearable health-monitoring systems have focused on advanced materials and system integration, and the number of high-performance wearable systems has been gradually increasing in recent years. However, there are still many challenges in these fields, such as balancing the trade-off between flexibility/stretchability, sensing performance, and the robustness of systems. For this reason, more evolution is required to promote the development of wearable health-monitoring systems. In this regard, this review summarizes some representative achievements and recent progress of wearable systems for health monitoring. Meanwhile, a strategy overview is presented about selecting materials, integrating systems, and monitoring biosignals. The next generation of wearable systems for accurate, portable, continuous, and long-term health monitoring will offer more opportunities for disease diagnosis and treatment.
    MeSH term(s) Wearable Electronic Devices ; Monitoring, Physiologic ; Telemedicine
    Language English
    Publishing date 2023-02-23
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2052857-7
    ISSN 1424-8220 ; 1424-8220
    ISSN (online) 1424-8220
    ISSN 1424-8220
    DOI 10.3390/s23052479
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Synthesizing high performance LNMO cathode materials with porous structure by manipulating reynolds number in a microreactor.

    Liu, Tongli / Deng, Hongjie / He, Fa / Wu, Yuqing / Wu, Zhenguo / Wan, Fang / Chen, Ting / Xu, Wenhua / Song, Yang / Guo, Xiaodong

    Nanotechnology

    2024  Volume 35, Issue 19

    Abstract: The demand for Lithium-ion batteries (LIBs) has significantly grown in the last decade due to their extensive use electric vehicles. To further advance the commercialization of LIBs for various applications, there is a pressing need to develop electrode ... ...

    Abstract The demand for Lithium-ion batteries (LIBs) has significantly grown in the last decade due to their extensive use electric vehicles. To further advance the commercialization of LIBs for various applications, there is a pressing need to develop electrode materials with enhanced performance. The porous microsphere morphology LiNi
    Language English
    Publishing date 2024-02-23
    Publishing country England
    Document type Journal Article
    ZDB-ID 1362365-5
    ISSN 1361-6528 ; 0957-4484
    ISSN (online) 1361-6528
    ISSN 0957-4484
    DOI 10.1088/1361-6528/ad2017
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: The Production Splitting Method of Offshore Multilayer Combined Water Flooding Gas Wells with Gas Dissolving.

    Ren, Chaoqun / Deng, Chuanzhong / Jiang, Zhehao / Fu, Qiang / Jiang, Lili / Guo, Yuchuan / Wu, Keliu

    ACS omega

    2024  Volume 9, Issue 11, Page(s) 12850–12865

    Abstract: Offshore gas reservoirs are characterized by thin interlayers, high production, few wells, etc., and are often exploited by multilayer combined mining, whereas the production dynamics of multilayer gas reservoirs are very different from those of single- ... ...

    Abstract Offshore gas reservoirs are characterized by thin interlayers, high production, few wells, etc., and are often exploited by multilayer combined mining, whereas the production dynamics of multilayer gas reservoirs are very different from those of single-layer gas reservoirs. Therefore, clarifying the gas production contribution of each layer in multilayer combined gas reservoirs is an important prerequisite for analyzing the potential of gas reservoirs and realizing efficient development. In this paper, unlike the past method of evaluating the gas production contribution of each layer by using the KH attribute of the reservoir, we combined the modified B-L equation considering CO
    Language English
    Publishing date 2024-03-06
    Publishing country United States
    Document type Journal Article
    ISSN 2470-1343
    ISSN (online) 2470-1343
    DOI 10.1021/acsomega.3c08949
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Wheat leaf area index prediction using data fusion based on high-resolution unmanned aerial vehicle imagery.

    Wu, Shuang / Deng, Lei / Guo, Lijie / Wu, Yanjie

    Plant methods

    2022  Volume 18, Issue 1, Page(s) 68

    Abstract: Background: Leaf Area Index (LAI) is half of the amount of leaf area per unit horizontal ground surface area. Consequently, accurate vegetation extraction in remote sensing imagery is critical for LAI estimation. However, most studies do not fully ... ...

    Abstract Background: Leaf Area Index (LAI) is half of the amount of leaf area per unit horizontal ground surface area. Consequently, accurate vegetation extraction in remote sensing imagery is critical for LAI estimation. However, most studies do not fully exploit the advantages of Unmanned Aerial Vehicle (UAV) imagery with high spatial resolution, such as not removing the background (soil and shadow, etc.). Furthermore, the advancement of multi-sensor synchronous observation and integration technology allows for the simultaneous collection of canopy spectral, structural, and thermal data, making it possible for data fusion.
    Methods: To investigate the potential of high-resolution UAV imagery combined with multi-sensor data fusion in LAI estimation. High-resolution UAV imagery was obtained with a multi-sensor integrated MicaSense Altum camera to extract the wheat canopy's spectral, structural, and thermal features. After removing the soil background, all features were fused, and LAI was estimated using Random Forest and Support Vector Machine Regression.
    Results: The results show that: (1) the soil background reduced the accuracy of the LAI prediction of wheat, and soil background could be effectively removed by taking advantage of high-resolution UAV imagery. After removing the soil background, the LAI prediction accuracy improved significantly, R
    Conclusions: The method of this study can be transferred to other sites with more extensive areas or similar agriculture structures, which will facilitate agricultural production and management.
    Language English
    Publishing date 2022-05-19
    Publishing country England
    Document type Journal Article
    ZDB-ID 2203723-8
    ISSN 1746-4811
    ISSN 1746-4811
    DOI 10.1186/s13007-022-00899-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Evaluation of microbiological epidemiology and clinical characteristics of maternal bloodstream infection: a 10 years retrospective study.

    Guo, Junfei / Wu, Yongbing / Li, Huan / Deng, Wenyu / Lai, Weiming / Gu, Chunming / Luo, Mingyong

    Frontiers in microbiology

    2024  Volume 14, Page(s) 1332611

    Abstract: Objective: Although the incidence of bloodstream infection (BSI) during pregnancy is relatively low, it can lead to unfavorable outcomes. The aim of our study was to analyze the clinical and microbiological characteristics of maternal bacteremia and to ... ...

    Abstract Objective: Although the incidence of bloodstream infection (BSI) during pregnancy is relatively low, it can lead to unfavorable outcomes. The aim of our study was to analyze the clinical and microbiological characteristics of maternal bacteremia and to assess maternal and fetal outcomes.
    Methods: Our study was a retrospective study conducted in a tertiary women and children's hospital in Guangzhou, China, from 2013 to 2022. Data were extracted from medical records and the laboratory information system. The participants were divided into groups, and the difference between the groups was analyzed.
    Results: The incidence of maternal BSI during the 10 years study period was 10.2 cases/10,000 maternities, with a peak found from 2014 to 2016.
    Conclusion: Maternal BSI is a rare event, but continuous monitoring on the aspects of pathogen composition, antimicrobial resistance characteristics, and risk factors for adverse outcomes remains necessary to further reduce poor outcomes and mitigate bacterial resistance.
    Language English
    Publishing date 2024-01-08
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587354-4
    ISSN 1664-302X
    ISSN 1664-302X
    DOI 10.3389/fmicb.2023.1332611
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Feasibility analysis of inactivating influenza A(H1N1) virus using UVC robot in classroom environment.

    Wu, Yizhen / Guo, Peiyao / Luo, Dekun / Deng, Jianyu / Yao, Huilu / Sun, Wenhong

    Heliyon

    2024  Volume 10, Issue 8, Page(s) e29540

    Abstract: Background: Starting from 2009, H1N1 has been one of the respiratory diseases that afflict the global population. Concurrently, due to the influence of COVID-19, it has become widely accepted that preventing the virus's spread necessitates personal ... ...

    Abstract Background: Starting from 2009, H1N1 has been one of the respiratory diseases that afflict the global population. Concurrently, due to the influence of COVID-19, it has become widely accepted that preventing the virus's spread necessitates personal protection measures and disinfection in public spaces.
    Experiments: This study conducted two experiments. In the classroom experiment, six UVC dose test points were calibrated to test whether the UVC dose at each testing point met the standards for inactivating IAVs and the time required to meet the standards. In the simulated classroom experiment, seven square slides made of IAVs were placed. After 10 min of robot movement, irradiated sterile square slides were made into suspension and injected into chicken embryos. Cultivate chicken embryos and conduct IAVs testing.
    Results: Classroom experiment has shown that 5 testing points can meet the standards for inactivating IAVs(3 mJ/cm
    Conclusion: The study presented that IAVs on the surface of an object can be effectively and rapidly deactivated at an irradiation density of 1.8 mW/cm
    Language English
    Publishing date 2024-04-15
    Publishing country England
    Document type Journal Article
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2024.e29540
    Database MEDical Literature Analysis and Retrieval System OnLINE

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