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  1. Article ; Online: Targeting Macrophage Epsins to Reverse Atherosclerosis.

    Li, Fang / Zhang, Hanrui

    Circulation research

    2023  Volume 132, Issue 1, Page(s) 7–9

    MeSH term(s) Humans ; Macrophages ; Atherosclerosis/drug therapy ; Plaque, Atherosclerotic
    Language English
    Publishing date 2023-01-05
    Publishing country United States
    Document type Editorial ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 80100-8
    ISSN 1524-4571 ; 0009-7330 ; 0931-6876
    ISSN (online) 1524-4571
    ISSN 0009-7330 ; 0931-6876
    DOI 10.1161/CIRCRESAHA.122.322273
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  2. Article: Commentary: Monocyte and macrophage lipid accumulation results in down-regulated type-I interferon responses.

    Li, Fang / Zhang, Hanrui

    Frontiers in cardiovascular medicine

    2023  Volume 9, Page(s) 1086136

    Language English
    Publishing date 2023-01-09
    Publishing country Switzerland
    Document type Journal Article ; Comment
    ZDB-ID 2781496-8
    ISSN 2297-055X
    ISSN 2297-055X
    DOI 10.3389/fcvm.2022.1086136
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  3. Article ; Online: Omics Approaches Unveiling the Biology of Human Atherosclerotic Plaques.

    Wu, Xun / Zhang, Hanrui

    The American journal of pathology

    2024  Volume 194, Issue 4, Page(s) 482–498

    Abstract: Atherosclerosis is a chronic inflammatory disease of the arterial wall, characterized by the buildup of plaques with the accumulation and transformation of lipids, immune cells, vascular smooth muscle cells, and necrotic cell debris. Plaques with ... ...

    Abstract Atherosclerosis is a chronic inflammatory disease of the arterial wall, characterized by the buildup of plaques with the accumulation and transformation of lipids, immune cells, vascular smooth muscle cells, and necrotic cell debris. Plaques with collagen-poor thin fibrous caps infiltrated by macrophages and lymphocytes are considered unstable because they are at the greatest risk of rupture and clinical events. However, the current histologic definition of plaque types may not fully capture the complex molecular nature of atherosclerotic plaque biology and the underlying mechanisms contributing to plaque progression, rupture, and erosion. The advances in omics technologies have changed the understanding of atherosclerosis plaque biology, offering new possibilities to improve risk prediction and discover novel therapeutic targets. Genomic studies have shed light on the genetic predisposition to atherosclerosis, and integrative genomic analyses expedite the translation of genomic discoveries. Transcriptomic, proteomic, metabolomic, and lipidomic studies have refined the understanding of the molecular signature of atherosclerotic plaques, aiding in data-driven hypothesis generation for mechanistic studies and offering new prospects for biomarker discovery. Furthermore, advancements in single-cell technologies and emerging spatial analysis techniques have unveiled the heterogeneity and plasticity of plaque cells. This review discusses key omics-based discoveries that have advanced the understanding of human atherosclerotic plaque biology, focusing on insights derived from omics profiling of human atherosclerotic vascular specimens.
    MeSH term(s) Humans ; Plaque, Atherosclerotic/genetics ; Plaque, Atherosclerotic/metabolism ; Plaque, Atherosclerotic/pathology ; Proteomics ; Atherosclerosis/pathology ; Macrophages/metabolism ; Extracellular Matrix/pathology
    Language English
    Publishing date 2024-01-25
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2943-9
    ISSN 1525-2191 ; 0002-9440
    ISSN (online) 1525-2191
    ISSN 0002-9440
    DOI 10.1016/j.ajpath.2023.12.007
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  4. Article ; Online: Nucleation of Pitting and Evolution of Stripping on Lithium-Metal Anodes.

    Zhang, Hanrui / Ulusel, Mert / Shi, Feifei

    ACS applied materials & interfaces

    2024  

    Abstract: The stripping reaction of lithium (Li) will greatly impact the cyclability and safety of Li-metal batteries. However, Li pits' nucleation and growth, the origin of uneven stripping, are still poorly understood. In this study, we analyze the nucleation ... ...

    Abstract The stripping reaction of lithium (Li) will greatly impact the cyclability and safety of Li-metal batteries. However, Li pits' nucleation and growth, the origin of uneven stripping, are still poorly understood. In this study, we analyze the nucleation mechanism of Li pits and their morphology evolution with a large population and electrode area (>0.45 cm
    Language English
    Publishing date 2024-04-25
    Publishing country United States
    Document type Journal Article ; Review
    ISSN 1944-8252
    ISSN (online) 1944-8252
    DOI 10.1021/acsami.4c01530
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  5. Article: Editorial: Lipids, lipoproteins and COVID-19.

    Ozcan, Mualla / Zhu, Xuewei / Zhang, Hanrui / Javaheri, Ali

    Frontiers in cardiovascular medicine

    2023  Volume 10, Page(s) 1293249

    Language English
    Publishing date 2023-11-01
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2781496-8
    ISSN 2297-055X
    ISSN 2297-055X
    DOI 10.3389/fcvm.2023.1293249
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  6. Article ; Online: Critical Role of In-Situ-Generated Eutectic Carbonates in Superstructured Solid Fuel Cells.

    Su, Hanrui / Zhang, Wei / Hu, Yun Hang

    The journal of physical chemistry letters

    2023  Volume 15, Issue 1, Page(s) 142–147

    Abstract: As a distinct type of fuel cell, a carbonate-superstructured solid fuel cell (CSSFC), which possesses excellent performance and easy fabrication as well as low cost, was recently invented by our group. Herein, we demonstrated the critical role of the in- ... ...

    Abstract As a distinct type of fuel cell, a carbonate-superstructured solid fuel cell (CSSFC), which possesses excellent performance and easy fabrication as well as low cost, was recently invented by our group. Herein, we demonstrated the critical role of the in-situ-generated eutectic carbonate phase in CSSFC. Namely, the in-situ generation of eutectic Li
    Language English
    Publishing date 2023-12-26
    Publishing country United States
    Document type Journal Article
    ISSN 1948-7185
    ISSN (online) 1948-7185
    DOI 10.1021/acs.jpclett.3c03354
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  7. Article ; Online: Statins for ACTA2 mutation-driven atherosclerosis?

    Zhang, Hanrui / Halmos, Benedek / Westerterp, Marit

    European heart journal

    2023  Volume 44, Issue 29, Page(s) 2727–2729

    MeSH term(s) Humans ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/therapeutic use ; Actins ; Cholesterol ; Atherosclerosis/drug therapy ; Atherosclerosis/genetics ; Mutation/genetics ; Myocytes, Smooth Muscle ; Muscle, Smooth
    Chemical Substances Hydroxymethylglutaryl-CoA Reductase Inhibitors ; Actins ; Cholesterol (97C5T2UQ7J) ; ACTA2 protein, human
    Language English
    Publishing date 2023-07-17
    Publishing country England
    Document type Editorial ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 603098-1
    ISSN 1522-9645 ; 0195-668X
    ISSN (online) 1522-9645
    ISSN 0195-668X
    DOI 10.1093/eurheartj/ehad364
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  8. Article ; Online: Dissecting cell type-specific impact in lysosomal acid lipase deficiency-associated disorders.

    Westerterp, Marit / Li, Fang / Zhang, Hanrui

    Journal of lipid research

    2023  Volume 64, Issue 12, Page(s) 100474

    MeSH term(s) Humans ; Wolman Disease/genetics ; Wolman Disease/complications ; Cholesterol Ester Storage Disease ; Sterol Esterase/genetics ; Lysosomes
    Chemical Substances Sterol Esterase (EC 3.1.1.13)
    Language English
    Publishing date 2023-11-14
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, N.I.H., Extramural ; Comment
    ZDB-ID 80154-9
    ISSN 1539-7262 ; 0022-2275
    ISSN (online) 1539-7262
    ISSN 0022-2275
    DOI 10.1016/j.jlr.2023.100474
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  9. Article ; Online: Break on Through to the Other Side: How Trained Monocytes Promote Recovery From Hind Limb Ischemia.

    Zhang, Hanrui / Wolf, Dennis

    Arteriosclerosis, thrombosis, and vascular biology

    2021  Volume 42, Issue 2, Page(s) 189–192

    MeSH term(s) Animals ; Hindlimb ; Ischemia ; Monocytes
    Language English
    Publishing date 2021-12-23
    Publishing country United States
    Document type Editorial ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 1221433-4
    ISSN 1524-4636 ; 1079-5642
    ISSN (online) 1524-4636
    ISSN 1079-5642
    DOI 10.1161/ATVBAHA.121.317257
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  10. Article ; Online: Structural design of La

    Ouyang, Erming / Xiang, Hanrui / Zhao, Rui / Yang, Hongwei / He, Wanyuan / Zhang, Ruiyue

    Environmental pollution (Barking, Essex : 1987)

    2024  Volume 345, Page(s) 123510

    Abstract: High levels of phosphorus released into the environment can cause eutrophication issues in wastewater, therefore discharge concentrations of such element are regulated in many countries. This study addresses the pressing need for effective phosphorus ... ...

    Abstract High levels of phosphorus released into the environment can cause eutrophication issues in wastewater, therefore discharge concentrations of such element are regulated in many countries. This study addresses the pressing need for effective phosphorus removal methods by developing a novel La
    MeSH term(s) Phosphorus/chemistry ; Wastewater ; Phosphates ; Adsorption ; Kinetics ; Magnetic Phenomena ; Water Pollutants, Chemical/analysis ; Charcoal
    Chemical Substances Phosphorus (27YLU75U4W) ; Wastewater ; biochar ; Phosphates ; Water Pollutants, Chemical ; Charcoal (16291-96-6)
    Language English
    Publishing date 2024-02-05
    Publishing country England
    Document type Journal Article
    ZDB-ID 280652-6
    ISSN 1873-6424 ; 0013-9327 ; 0269-7491
    ISSN (online) 1873-6424
    ISSN 0013-9327 ; 0269-7491
    DOI 10.1016/j.envpol.2024.123510
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