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  1. Article ; Online: L

    Chen, Cheng-Neng / Wang, Mao-Hsien / Soung, Hung-Sheng / Chen, Shu-Mei / Fang, Chih-Hsiang / Lin, Yi-Wen / Tseng, Hsiang-Chien

    Neurotoxicity research

    2022  Volume 40, Issue 1, Page(s) 241–258

    Abstract: Rotenone (RO)-induced neurotoxicity exhibits pathophysiological features similar to those reported in patients with Parkinson's disease (PD), such as nitrosative and oxidative stress, mitochondrial dysfunction, and neural cytoarchitecture alterations in ... ...

    Abstract Rotenone (RO)-induced neurotoxicity exhibits pathophysiological features similar to those reported in patients with Parkinson's disease (PD), such as nitrosative and oxidative stress, mitochondrial dysfunction, and neural cytoarchitecture alterations in the substantia nigra pars compacta (SNpc)/striatum (ST), which has been used for decades as an animal model of PD in humans.
    MeSH term(s) Animals ; Disease Models, Animal ; Glutamates/therapeutic use ; Humans ; Neuroprotective Agents/pharmacology ; Neuroprotective Agents/therapeutic use ; Parkinsonian Disorders/metabolism ; Rats ; Rotenone/toxicity
    Chemical Substances Glutamates ; Neuroprotective Agents ; Rotenone (03L9OT429T) ; theanine (8021PR16QO)
    Language English
    Publishing date 2022-01-06
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2036826-4
    ISSN 1476-3524 ; 1029-8428
    ISSN (online) 1476-3524
    ISSN 1029-8428
    DOI 10.1007/s12640-021-00451-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5749: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: L

    Yang, Qinmin / Jiao, Xuguo / Luo, Qingshun / Chen, Qi / Sun, Youxian

    ISA transactions

    2020  Volume 103, Page(s) 28–36

    Abstract: ... wind conditions, such as wind gusts, can even lead to shut-downs. In this paper, a novel L ...

    Abstract In conditions of above rated wind speed, the power output of a wind turbine should be maintained at rated power to prevent overheating of generators and power electronics systems. Furthermore, extreme wind conditions, such as wind gusts, can even lead to shut-downs. In this paper, a novel L
    Language English
    Publishing date 2020-04-13
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2012746-7
    ISSN 1879-2022 ; 0019-0578
    ISSN (online) 1879-2022
    ISSN 0019-0578
    DOI 10.1016/j.isatra.2020.04.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: L

    Soung, Hung-Sheng / Wang, Mao-Hsien / Chang, Kuo-Chi / Chen, Cheng-Neng / Chang, Yi / Yang, Chih-Chuan / Tseng, Hsiang-Chien

    Neurotoxicity research

    2018  Volume 34, Issue 3, Page(s) 375–387

    Abstract: Reserpine (RES)-induced orofacial dyskinesia (OD) has been used as an animal model for human tardive dyskinesia (TD) for decades, due to its strong pathophysiological association with striatal oxidative stress and neural cytoarchitecture alteration. ...

    Abstract Reserpine (RES)-induced orofacial dyskinesia (OD) has been used as an animal model for human tardive dyskinesia (TD) for decades, due to its strong pathophysiological association with striatal oxidative stress and neural cytoarchitecture alteration.
    MeSH term(s) Analysis of Variance ; Animals ; Antipsychotic Agents/toxicity ; Caspase 3/metabolism ; Cytokines/metabolism ; Disease Models, Animal ; Dose-Response Relationship, Drug ; Dyskinesias/drug therapy ; Dyskinesias/etiology ; Glutamates/therapeutic use ; Glutathione/metabolism ; Lipid Peroxidation/drug effects ; Male ; Neurotransmitter Agents/metabolism ; Rats ; Rats, Wistar ; Reserpine/toxicity ; Superoxide Dismutase/metabolism
    Chemical Substances Antipsychotic Agents ; Cytokines ; Glutamates ; Neurotransmitter Agents ; theanine (8021PR16QO) ; Reserpine (8B1QWR724A) ; Superoxide Dismutase (EC 1.15.1.1) ; Caspase 3 (EC 3.4.22.-) ; Glutathione (GAN16C9B8O)
    Language English
    Publishing date 2018-04-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2036826-4
    ISSN 1476-3524 ; 1029-8428
    ISSN (online) 1476-3524
    ISSN 1029-8428
    DOI 10.1007/s12640-018-9897-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5749: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: (L)

    Li, Zhongshu / Chen, Xiaodan / Andrada, Diego M / Frenking, Gernot / Benkö, Zoltán / Li, Yaqi / Harmer, Jeffrey R / Su, Cheng-Yong / Grützmacher, Hansjörg

    Angewandte Chemie (International ed. in English)

    2017  Volume 56, Issue 21, Page(s) 5744–5749

    Abstract: Carbon phosphides, ... ...

    Abstract Carbon phosphides, C
    Language English
    Publishing date 2017-04-24
    Publishing country Germany
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2011836-3
    ISSN 1521-3773 ; 1433-7851
    ISSN (online) 1521-3773
    ISSN 1433-7851
    DOI 10.1002/anie.201612247
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  5. Article ; Online: L-GrAFT

    Li, Songming / Luo, Qijie / Chen, Shirui / Jia, Zehua / Wang, Tielong / Yu, Xinyu / Wang, Wenjing / YuyiZhang / Zhu, Jiaxing / Deng, Feiwen / Sun, Qiang / Guo, Zhiyong / He, Xiaoshun

    Journal of clinical and translational hepatology

    2023  Volume 12, Issue 1, Page(s) 62–69

    Abstract: ... the Liver Graft Assessment Following Transplantation (L-GrAFT) risk model in a Chinese cohort of 942 adult ... patients undergoing primary liver transplantation at three Chinese centers. L-GrAFT (L-GrAFT: Results: L ... GrAFT: Conclusions: The accuracy of L-GrAFT ...

    Abstract Background and aims: Increasing utilization of extended criteria donor leads to an increasing rate of early allograft failure after liver transplantation. However, consensus of definition of early allograft failure is lacking.
    Methods: A retrospective, multicenter study was performed to validate the Liver Graft Assessment Following Transplantation (L-GrAFT) risk model in a Chinese cohort of 942 adult patients undergoing primary liver transplantation at three Chinese centers. L-GrAFT (L-GrAFT
    Results: L-GrAFT
    Conclusions: The accuracy of L-GrAFT
    Language English
    Publishing date 2023-08-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 3019822-7
    ISSN 2310-8819 ; 2225-0719
    ISSN (online) 2310-8819
    ISSN 2225-0719
    DOI 10.14218/JCTH.2023.00178
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Trifunctional L-Cysteine Assisted Construction of MoO

    Gong, Feilong / Chen, Zhilin / Zhao, Yang / Zhang, Hongge / Zeng, Guang / Yao, Cuijie / Gong, Lihua / Zhang, Yonghui / Liu, Jian / Wei, Shizhong

    Small (Weinheim an der Bergstrasse, Germany)

    2024  , Page(s) e2307986

    Abstract: The volume collapse and slow kinetics reaction of anode materials are two key issues for sodium ion batteries (SIBs). Herein, an "embryo" strategy is proposed for synthesis of nanorod-embedded ... ...

    Abstract The volume collapse and slow kinetics reaction of anode materials are two key issues for sodium ion batteries (SIBs). Herein, an "embryo" strategy is proposed for synthesis of nanorod-embedded MoO
    Language English
    Publishing date 2024-01-08
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2168935-0
    ISSN 1613-6829 ; 1613-6810
    ISSN (online) 1613-6829
    ISSN 1613-6810
    DOI 10.1002/smll.202307986
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: A Tri-Enzyme Cascade for Efficient Production of L-2-Aminobutyrate from L-Threonine.

    Li, Xin / Gao, Changzheng / Wei, Wanqing / Song, Wei / Meng, Weiwei / Liu, Jia / Chen, Xiulai / Gao, Cong / Guo, Liang / Liu, Liming / Wu, Jing

    Chembiochem : a European journal of chemical biology

    2023  Volume 24, Issue 15, Page(s) e202300148

    Abstract: L-2-aminobutyrate (L-ABA) is an important chiral drug intermediate with a key role ... of L-ABA in a tri-enzymatic cascade in Escherichia coli BL21 (DE3) using a cost-effective L-Thr. Low ...

    Abstract L-2-aminobutyrate (L-ABA) is an important chiral drug intermediate with a key role in modern medicinal chemistry. Here, we describe the development of an efficient method for the asymmetric synthesis of L-ABA in a tri-enzymatic cascade in Escherichia coli BL21 (DE3) using a cost-effective L-Thr. Low activity of leucine dehydrogenase from Bacillus thuringiensis (BtLDH) and unbalanced expression of enzymes in the cascade were major challenges. Mechanism-based protein engineering generated the optimal triple variant BtLDH
    MeSH term(s) Threonine/metabolism ; Escherichia coli/metabolism ; Aminobutyrates/metabolism ; Metabolic Engineering
    Chemical Substances Threonine (2ZD004190S) ; Aminobutyrates
    Language English
    Publishing date 2023-06-28
    Publishing country Germany
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2020469-3
    ISSN 1439-7633 ; 1439-4227
    ISSN (online) 1439-7633
    ISSN 1439-4227
    DOI 10.1002/cbic.202300148
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  8. Article ; Online: L-theanine attenuates H

    Li, Zhongqing / Huang, Zhiqing / Jia, Gang / Zhao, Hua / Liu, Guangmang / Chen, Xiaoling

    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association

    2024  Volume 186, Page(s) 114561

    Abstract: This study investigated the protective effects of L-theanine on hydrogen peroxide (H ...

    Abstract This study investigated the protective effects of L-theanine on hydrogen peroxide (H
    MeSH term(s) Humans ; Hydrogen Peroxide/toxicity ; NF-kappa B/metabolism ; MAP Kinase Signaling System ; Intestinal Diseases ; Apoptosis ; p38 Mitogen-Activated Protein Kinases/genetics ; p38 Mitogen-Activated Protein Kinases/metabolism ; Inflammation ; Epithelial Cells/metabolism ; Glutamates
    Chemical Substances Hydrogen Peroxide (BBX060AN9V) ; NF-kappa B ; theanine (8021PR16QO) ; p38 Mitogen-Activated Protein Kinases (EC 2.7.11.24) ; Glutamates
    Language English
    Publishing date 2024-03-02
    Publishing country England
    Document type Journal Article
    ZDB-ID 782617-5
    ISSN 1873-6351 ; 0278-6915
    ISSN (online) 1873-6351
    ISSN 0278-6915
    DOI 10.1016/j.fct.2024.114561
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 529: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  9. Article ; Online: L-Theanine and Immunity: A Review.

    Chen, Shuna / Kang, Jiaxin / Zhu, Huanqing / Wang, Kaixi / Han, Ziyi / Wang, Leyu / Liu, Junsheng / Wu, Yuanyuan / He, Puming / Tu, Youying / Li, Bo

    Molecules (Basel, Switzerland)

    2023  Volume 28, Issue 9

    Abstract: L-theanine (N-ethyl-γ-glutamine) is the main amino acid in tea leaves. It not only contributes ... activities, the immunomodulatory effects of L-theanine have received less attention. Clinical and epidemiological studies have ... shown that L-theanine reduces immunosuppression caused by strenuous exercise and prevents colds and ...

    Abstract L-theanine (N-ethyl-γ-glutamine) is the main amino acid in tea leaves. It not only contributes to tea flavor but also possesses several health benefits. Compared with its sedative and calming activities, the immunomodulatory effects of L-theanine have received less attention. Clinical and epidemiological studies have shown that L-theanine reduces immunosuppression caused by strenuous exercise and prevents colds and influenza by improving immunity. Numerous cell and animal studies have proven that theanine plays an immunoregulatory role in inflammation, nerve damage, the intestinal tract, and tumors by regulating γδT lymphocyte function, glutathione (GSH) synthesis, and the secretion of cytokines and neurotransmitters. In addition, theanine can be used as an immunomodulator in animal production. This article reviews the research progress of L-theanine on immunoregulation and related mechanisms, as well as its application in poultry and animal husbandry. It is hoped that this work will be beneficial to future related research.
    MeSH term(s) Animals ; Glutamates/chemistry ; Cytokines ; Immunity ; Tea/chemistry
    Chemical Substances theanine (8021PR16QO) ; Glutamates ; Cytokines ; Tea
    Language English
    Publishing date 2023-05-01
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules28093846
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.MO 81: Show issues

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  10. Article ; Online: L-Borneol 7-O-[

    Tong, Ziyi / Li, Gaowen / Su, Chengxiao / Zhou, Liyan / Zhang, Ling / Chen, Qun / Xia, Qing

    Journal of immunology research

    2022  Volume 2022, Page(s) 5758303

    Abstract: ... myocardial infarction (AMI). L-Borneol 7-O-[ ...

    Abstract Ischemia/reperfusion (I/R) is a primary cause of morbidity and mortality in acute myocardial infarction (AMI). L-Borneol 7-O-[
    MeSH term(s) Animals ; Apoptosis ; Camphanes ; Hypoxia/metabolism ; Myocardial Infarction/metabolism ; Myocardial Reperfusion Injury/drug therapy ; Myocardial Reperfusion Injury/metabolism ; Myocardial Reperfusion Injury/pathology ; Myocytes, Cardiac/metabolism ; Phosphatidylinositol 3-Kinases/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; Rats ; Signal Transduction ; TOR Serine-Threonine Kinases/metabolism
    Chemical Substances Camphanes ; mTOR protein, rat (EC 2.7.1.1) ; Proto-Oncogene Proteins c-akt (EC 2.7.11.1) ; TOR Serine-Threonine Kinases (EC 2.7.11.1) ; isoborneol (L88RA8N5EG)
    Language English
    Publishing date 2022-05-12
    Publishing country Egypt
    Document type Journal Article
    ZDB-ID 2817541-4
    ISSN 2314-7156 ; 2314-7156
    ISSN (online) 2314-7156
    ISSN 2314-7156
    DOI 10.1155/2022/5758303
    Database MEDical Literature Analysis and Retrieval System OnLINE

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