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Article ; Online: Empirical Analysis of Export Tax Rebate on Inwards Foreign Direct Investment in China

Bingqiang Li / Xi Li / Jinzhi Li / Hongchun Lin / Baojuan Rui

SAGE Open, Vol

2023 Volume 13

Abstract: Export tax rebate (ETR) and inwards foreign direct investment (IFDI) are important driving forces for the steady development of China’s export-oriented economy. Based on data from 2004 to 2019, this study puts forward relevant assumptions on constructing ...

Abstract	Export tax rebate (ETR) and inwards foreign direct investment (IFDI) are important driving forces for the steady development of China’s export-oriented economy. Based on data from 2004 to 2019, this study puts forward relevant assumptions on constructing a model for empirically analyzing the impact of the ETR on China’s IFDI from the perspective of the national and the sub-national. The result demonstrates that there exists a complementary relationship between the ETR and IFDI; the weak lag effect of ETR on IFDI in the eastern, middle, and western regions of China; an explicit impact on the performance in the western region, which lags behind only one period; and no significant lag effect of ETR on IFDI in developed, moderately developed, and underdeveloped regions. On the basis of this evaluation, the conclusion could be achieved that that ETR has a significant effect on IFDI, though there may be differences in the direction and value of the impact. The highlight of this research is to detect the impact of ETR on IFDI by taking China as a case, and achieved that there exist sub-national differences, including the geographical and development-level differences.
Keywords	History of scholarship and learning. The humanities ; AZ20-999 ; Social Sciences ; H
Subject code	950
Language	English
Publishing date	2023-12-01T00:00:00Z
Publisher	SAGE Publishing
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: The Histone Variant H3.3 Is Required for Plant Growth and Fertility in

Long, Xiaogang / Yang, Wandong / Lv, Yanfang / Zhong, Xiaoming / Chen, Lin / Li, Qingzhu / Lv, Zhaopeng / Li, Yanzhuo / Cai, Yajun / Yang, Hongchun

International journal of molecular sciences

2024 Volume 25, Issue 5

Abstract: Histones are the core components of the eukaryote chromosome, and have been implicated in transcriptional gene regulation. There are three major isoforms of histone H3 ... ...

Abstract	Histones are the core components of the eukaryote chromosome, and have been implicated in transcriptional gene regulation. There are three major isoforms of histone H3 in
MeSH term(s)	Arabidopsis/genetics ; Histones/metabolism ; Arabidopsis Proteins/genetics ; Transcription Factors/metabolism ; Plant Growth Regulators/metabolism
Chemical Substances	Histones ; Arabidopsis Proteins ; Transcription Factors ; Plant Growth Regulators
Language	English
Publishing date	2024-02-22
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2019364-6
ISSN	1422-0067 ; 1422-0067 ; 1661-6596
ISSN (online)	1422-0067
ISSN	1422-0067 ; 1661-6596
DOI	10.3390/ijms25052549
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Serum Lactate Is an Indicator for Short-Term and Long-Term Mortality in Patients with Acute Pancreatitis.

Zeng, Zhao / Huang, Rong / Lin, Hang / Peng, Hongchun / Luo, Ju / Ding, Ning

Digestive diseases and sciences

2024

Abstract: Background: Serum lactate, as a single and an easily available biomarker, has been applied in various diseases.: Aims: In this study, we aimed to explore the predictive value of serum lactate for short-term and long-term prognosis in acute ... ...

Abstract	Background: Serum lactate, as a single and an easily available biomarker, has been applied in various diseases. Aims: In this study, we aimed to explore the predictive value of serum lactate for short-term and long-term prognosis in acute pancreatitis (AP) admitted in intensive care unit (ICU) based on a large-scale database. Methods: AP patients admitted in ICU in the MIMIC-IV database were included. We constructed three different models to investigate the relationships between serum lactate and clinical outcomes, including 30-day, 180-day and 1-year mortality in AP. Smooth fitting curves were performed for intuitively demonstrating the relationship between serum lactate and different outcomes in AP by the generalized additive model. Results: A total of 895 AP patients admitted in ICU were included. The mortalities of 30 days, 180 days, and 1 year were 12.63% (n = 113), 16.87% (n = 151), and 17.54% (n = 157). In model B, with 1-mmol/L increment in serum lactate, the values of OR in 30-day, 180-day and 1-year mortality were 1.20 (95%CI 1.04-1.37, P = 0.0094), 1.21 (95%CI 1.06-1.37, P = 0.0039), and 1.21 (95%CI 1.07-1.38, P = 0.0035). The AUCs of serum lactate for predicting 30-day, 180-day, and 1-year mortality in AP were 0.688 (95%CI 0.633-0.743), 0.655 (95%CI 0.605-0.705), and 0.653 (95%CI 0.603-0.701), respectively. The cut-off value of serum lactate predicting 30-day, 180-day and 1-year mortality in AP was 2.4 mmol/L. Conclusion: Serum lactate could be an indicator for short-term and long-term mortality in patients with AP admitted in ICU.
Language	English
Publishing date	2024-04-09
Publishing country	United States
Document type	Journal Article
ZDB-ID	304250-9
ISSN	1573-2568 ; 0163-2116
ISSN (online)	1573-2568
ISSN	0163-2116
DOI	10.1007/s10620-024-08419-4
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Article ; Online: Removal effects and potential mechanisms of bisphenol A and 17α-ethynylestradiol by Biogenic Mn oxides generated by Bacillus sp. WH4.

Lin, Yan / Liu, Hongchun / Wang, Xiaojie

Environmental science and pollution research international

2022 Volume 29, Issue 38, Page(s) 57261–57276

Abstract: Endocrine disrupting compounds (EDCs), such as bisphenol A (BPA) and 17α-ethynylestradiol (EE2), have increasingly negative effects on human and wildlife health. In this study, the biogenic Mn oxides (BMOs) generated by Bacillus sp. WH4 were ... ...

Abstract	Endocrine disrupting compounds (EDCs), such as bisphenol A (BPA) and 17α-ethynylestradiol (EE2), have increasingly negative effects on human and wildlife health. In this study, the biogenic Mn oxides (BMOs) generated by Bacillus sp. WH4 were characterized, and the removal effects and reaction kinetics of BPA and EE2 by BMOs under different pH values, initial organic concentrations, and dosages of BMOs were discussed. The results showed that the formation of BMOs was extracellular process, and Mn(II) was oxidized to Mn(III) and Mn(IV) with 23.56% and 76.44%, respectively. The degradation processes of BPA and EE2 by BMOs followed first-order reaction kinetics, and the removal effect decreased with increasing initial BPA/EE2 concentrations and increased with increasing dosages of BMOs. However, the removal effect of BPA by BMOs decreased and then increased with increasing pH, while the removal effect of EE2 by BMOs decreased with increasing pH. Under optimal conditions, the removal efficiency of BPA and EE2 exceeded 98.2% and 94.3%, respectively. Additionally, this study showed that BMOs degraded BPA by coupling, oxidative condensation, substitution, and elimination reactions to obtain sixteen intermediate products and EE2 by substitution and elimination reactions to obtain seven intermediate products.
MeSH term(s)	Bacillus/metabolism ; Benzhydryl Compounds/chemistry ; Ethinyl Estradiol/chemistry ; Humans ; Oxides/metabolism ; Phenols/chemistry
Chemical Substances	Benzhydryl Compounds ; Oxides ; Phenols ; Ethinyl Estradiol (423D2T571U) ; bisphenol A (MLT3645I99)
Language	English
Publishing date	2022-03-29
Publishing country	Germany
Document type	Journal Article
ZDB-ID	1178791-0
ISSN	1614-7499 ; 0944-1344
ISSN (online)	1614-7499
ISSN	0944-1344
DOI	10.1007/s11356-022-19831-6
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Article ; Online: An Unsupervised Feature Extraction Approach Based on Self-Expression.

Qu, Hongchun / Zheng, Yangqi / Li, Lin / Guo, Fei

Big data

2022 Volume 11, Issue 1, Page(s) 18–34

Abstract: Feature extraction algorithms lack good interpretability during the projection learning. To solve this problem, an unsupervised feature extraction algorithm, that is, block diagonal projection (BDP), based on self-expression is proposed. Specifically, if ...

Abstract	Feature extraction algorithms lack good interpretability during the projection learning. To solve this problem, an unsupervised feature extraction algorithm, that is, block diagonal projection (BDP), based on self-expression is proposed. Specifically, if the original data are projected into a low-dimensional subspace by a feature extraction algorithm, although the data may be more compact, the new features obtained may not be as explanatory as the original sample features. Therefore, by imposing L2,1 norm constraint on the projection matrix, the projection matrix can be of row sparsity. On one hand, discriminative features can be selected to make the projection matrix to be more interpretable. On the other hand, irrelevant or redundant features can be suppressed. The proposed model integrates feature extraction and selection into one framework. In addition, since self-expression can well excavate the correlation between samples or sample features, the unsupervised feature extraction task can be better guided using this property between them. At the same time, the block diagonal representation regular term is introduced to directly pursue the block diagonal representation. Thus, the accuracy of pattern recognition tasks such as clustering and classification can be improved. Finally, the effectiveness of BDP in linear dimensionality reduction and classification is proved on various reference datasets. The experimental results show that this algorithm is superior to previous feature extraction counterparts.
MeSH term(s)	Pattern Recognition, Automated/methods ; Algorithms ; Learning ; Cluster Analysis
Language	English
Publishing date	2022-05-10
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ISSN	2167-647X
ISSN (online)	2167-647X
DOI	10.1089/big.2021.0420
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Article: Removal effects and potential mechanisms of bisphenol A and 17α-ethynylestradiol by Biogenic Mn oxides generated by Bacillus sp. WH4

Lin, Yan / Liu, Hongchun / Wang, Xiaojie

Environmental science and pollution research. 2022 Aug., v. 29, no. 38

2022

Abstract	Endocrine disrupting compounds (EDCs), such as bisphenol A (BPA) and 17α-ethynylestradiol (EE2), have increasingly negative effects on human and wildlife health. In this study, the biogenic Mn oxides (BMOs) generated by Bacillus sp. WH4 were characterized, and the removal effects and reaction kinetics of BPA and EE2 by BMOs under different pH values, initial organic concentrations, and dosages of BMOs were discussed. The results showed that the formation of BMOs was extracellular process, and Mn(II) was oxidized to Mn(III) and Mn(IV) with 23.56% and 76.44%, respectively. The degradation processes of BPA and EE2 by BMOs followed first-order reaction kinetics, and the removal effect decreased with increasing initial BPA/EE2 concentrations and increased with increasing dosages of BMOs. However, the removal effect of BPA by BMOs decreased and then increased with increasing pH, while the removal effect of EE2 by BMOs decreased with increasing pH. Under optimal conditions, the removal efficiency of BPA and EE2 exceeded 98.2% and 94.3%, respectively. Additionally, this study showed that BMOs degraded BPA by coupling, oxidative condensation, substitution, and elimination reactions to obtain sixteen intermediate products and EE2 by substitution and elimination reactions to obtain seven intermediate products.
Keywords	Bacillus (bacteria) ; bisphenol A ; condensation reactions ; humans ; pH ; pollution ; reaction kinetics ; research ; wildlife
Language	English
Dates of publication	2022-08
Size	p. 57261-57276.
Publishing place	Springer Berlin Heidelberg
Document type	Article
ZDB-ID	1178791-0
ISSN	1614-7499 ; 0944-1344
ISSN (online)	1614-7499
ISSN	0944-1344
DOI	10.1007/s11356-022-19831-6
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Effects of climate change on vegetation dynamics of the Qinghai-Tibet Plateau, a causality analysis using empirical dynamic modeling

Zhaoni Li / Hongchun Qu / Lin Li / Jian Zheng / Dianwen Wei / Fude Wang

Heliyon, Vol 9, Iss 5, Pp e16001- (2023)

2023

Abstract: Given the vital role of the Qinghai-Tibet Plateau (QTP) as water tower in Asia and regulator for regional and even global climate, the relationship between climate change and vegetation dynamics on it has received considerable focused attention. Climate ... ...

Abstract	Given the vital role of the Qinghai-Tibet Plateau (QTP) as water tower in Asia and regulator for regional and even global climate, the relationship between climate change and vegetation dynamics on it has received considerable focused attention. Climate change may influence the vegetation growth on the plateau, but clear empirical evidence of such causal linkages is sparse. Herein, using datasets CRU-TS v4.04 and AVHHR NDVI from 1981 to 2019, we quantify causal effects of climate factors on vegetation dynamics with an empirical dynamical model (EDM) -- a nonlinear dynamical systems analysis approach based on state-space reconstruction rather than correlation. Results showed the following: (1) climate change promotes the growth of vegetation on the QTP, and specifically, this favorable influence of temperature is stronger than precipitation's; (2) the direction and strength of climate effects on vegetation varied over time, and the effects are seasonally different; (3) a significant increase in temperature and a slight increase in precipitation are beneficial to vegetation growth, specifically, NDVI will increase within 2% in the next 40 years with the climate trend of warming and humidity. Besides the above results, another interesting finding is that the two seasons in which precipitation strongly influence vegetation in the Three-River Source region (part of the QTP) are spring and winter. This study provides insights into the mechanisms by which climate change affects vegetation growth on the QTP, aiding in the modeling of vegetation dynamics in future scenarios.
Keywords	Climate change ; NDVI ; EDM ; Causal effects ; Science (General) ; Q1-390 ; Social sciences (General) ; H1-99
Subject code	550 ; 910
Language	English
Publishing date	2023-05-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Elucidating the role of nicotinamide N-methyltransferase-p53 axis in the progression of chronic kidney disease

Xin Zhen / Yuxiang Sun / Hongchun Lin / Yuebo Huang / Tianwei Liu / Yuanqing Li / Hui Peng

PeerJ, Vol 11, p e

2023 Volume 16301

Abstract: Background Chronic kidney disease (CKD) is a significant global health issue characterized by progressive loss of kidney function. Renal interstitial fibrosis (TIF) is a common feature of CKD, but current treatments are seldom effective in reversing TIF. ...

Abstract	Background Chronic kidney disease (CKD) is a significant global health issue characterized by progressive loss of kidney function. Renal interstitial fibrosis (TIF) is a common feature of CKD, but current treatments are seldom effective in reversing TIF. Nicotinamide N-methyltransferase (NNMT) has been found to increase in kidneys with TIF, but its role in renal fibrosis is unclear. Methods Using mice with unilateral ureteral obstruction (UUO) and cultured renal interstitial fibroblast cells (NRK-49F) stimulated with transforming growth factor-β1 (TGF-β1), we investigated the function of NNMT in vivo and in vitro. Results We performed single-cell transcriptome sequencing (scRNA-seq) on the kidneys of mice and found that NNMT increased mainly in fibroblasts of UUO mice compared to sham mice. Additionally, NNMT was positively correlated with the expression of renal fibrosis-related genes after UUO injury. Knocking down NNMT expression reduced fibroblast activation and was accompanied by an increase in DNA methylation of p53 and a decrease in its phosphorylation. Conclusions Our findings suggest that chronic kidney injury leads to an accumulation of NNMT, which might decrease p53 methylation, and increase the expression and activity of p53. We propose that NNMT promotes fibroblast activation and renal fibrosis, making NNMT a novel target for preventing and treating renal fibrosis.
Keywords	Chronic kidney disease ; Nicotinamide N-methyltransferase ; Renal interstitial fibrosis ; p53 ; Post-translational modification ; Medicine ; R ; Biology (General) ; QH301-705.5
Subject code	616
Language	English
Publishing date	2023-11-01T00:00:00Z
Publisher	PeerJ Inc.
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: The Effects of Hemisphere Dome Orientation on the Structure of Diamond-like Carbon Film Prepared Using Ion Beam Assisted Deposition.

Shang, Peng / Ma, Yuanfei / Zhang, Zhenyun / Sun, Peng / Liu, Huasong / Shi, Hongchun / Lin, Quan / Xue, Tao / Ji, Yiqin

Materials (Basel, Switzerland)

2023 Volume 16, Issue 5

Abstract: Diamond-like carbon (DLC) has attracted significant attention in the recent decades because of its unique properties and applications. Ion beam assisted deposition (IBAD) has been widely established in industry due to the advantages of easy handling and ... ...

Abstract	Diamond-like carbon (DLC) has attracted significant attention in the recent decades because of its unique properties and applications. Ion beam assisted deposition (IBAD) has been widely established in industry due to the advantages of easy handling and scalability. In this work, a hemisphere dome model is specially designed as a substrate. The influence of the surface orientation on the coating thickness, Raman I
Language	English
Publishing date	2023-02-21
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2487261-1
ISSN	1996-1944
ISSN	1996-1944
DOI	10.3390/ma16051773
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Article ; Online: Elucidating the role of nicotinamide N-methyltransferase-p53 axis in the progression of chronic kidney disease.

Zhen, Xin / Sun, Yuxiang / Lin, Hongchun / Huang, Yuebo / Liu, Tianwei / Li, Yuanqing / Peng, Hui

PeerJ

2023 Volume 11, Page(s) e16301

Abstract: Background: Chronic kidney disease (CKD) is a significant global health issue characterized by progressive loss of kidney function. Renal interstitial fibrosis (TIF) is a common feature of CKD, but current treatments are seldom effective in reversing ... ...

Abstract	Background: Chronic kidney disease (CKD) is a significant global health issue characterized by progressive loss of kidney function. Renal interstitial fibrosis (TIF) is a common feature of CKD, but current treatments are seldom effective in reversing TIF. Nicotinamide N-methyltransferase (NNMT) has been found to increase in kidneys with TIF, but its role in renal fibrosis is unclear. Methods: Using mice with unilateral ureteral obstruction (UUO) and cultured renal interstitial fibroblast cells (NRK-49F) stimulated with transforming growth factor-β1 (TGF-β1), we investigated the function of NNMT Results: We performed single-cell transcriptome sequencing (scRNA-seq) on the kidneys of mice and found that NNMT increased mainly in fibroblasts of UUO mice compared to sham mice. Additionally, NNMT was positively correlated with the expression of renal fibrosis-related genes after UUO injury. Knocking down NNMT expression reduced fibroblast activation and was accompanied by an increase in DNA methylation of p53 and a decrease in its phosphorylation. Conclusions: Our findings suggest that chronic kidney injury leads to an accumulation of NNMT, which might decrease p53 methylation, and increase the expression and activity of p53. We propose that NNMT promotes fibroblast activation and renal fibrosis, making NNMT a novel target for preventing and treating renal fibrosis.
MeSH term(s)	Fibrosis ; Kidney/metabolism ; Nicotinamide N-Methyltransferase/genetics ; Renal Insufficiency, Chronic/genetics ; Tumor Suppressor Protein p53/metabolism ; Ureteral Obstruction/genetics ; Animals ; Mice
Chemical Substances	Nicotinamide N-Methyltransferase (EC 2.1.1.1) ; Tumor Suppressor Protein p53 ; Nnmt protein, mouse (EC 2.1.1.1)
Language	English
Publishing date	2023-11-08
Publishing country	United States
Document type	Journal Article
ZDB-ID	2703241-3
ISSN	2167-8359 ; 2167-8359
ISSN (online)	2167-8359
ISSN	2167-8359
DOI	10.7717/peerj.16301
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