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Article ; Online: Identification of critical airports for controlling global infectious disease outbreaks: Stress-tests focusing in Europe.

Nikolaou, Paraskevas / Dimitriou, Loukas

Journal of air transport management

2020 Volume 85, Page(s) 101819

Abstract: As the global population increases and transportation connectivity improves in quality and prices, the demand for mobility increases, especially in long-haul services. According to the 2017 report of the European Commission in Mobility and Transport, the ...

Abstract	As the global population increases and transportation connectivity improves in quality and prices, the demand for mobility increases, especially in long-haul services. According to the 2017 report of the European Commission in Mobility and Transport, the performance of all modes for passenger transport (roadways and airways) are reaching record highs. Although the benefits of the increased demand for mobility are substantial and welcome, an effort should be paid such as to ameliorate possible threatening side-effects that may also arise. As World Health Organization (WHO) denotes and as has been evident from the global COVID-19 epidemic outbreak, infectious diseases can be spread directly or indirectly from one person to another under common exposure circumstances such as air transportation (especially long-haul airline connections) that may act as the medium for transmitting and spreading infectious diseases. In this paper, analytical and realistic models have been integrated, for providing evidence on the spread dynamics of infectious diseases that may face Europe through the airlines system. In particular, a detailed epidemiological model has been integrated with the airlines' and land transport network, able to simulate the epidemic spread of infectious diseases originated from distant locations. Additionally, a wide set of experiments and simulations have been conducted, providing results from detailed stress-tests covering both mild as well as aggressive cases of epidemic spreading scenarios. The results provide convincing evidence on the effectiveness that the European airports' system offer in controlling the emergence of epidemics, but also on the time and extent that controlling measures should be taken in order to break the chain of infections in realistic cases.
Keywords	covid19
Language	English
Publishing date	2020-04-10
Publishing country	England
Document type	Journal Article
ISSN	1873-2089
ISSN (online)	1873-2089
DOI	10.1016/j.jairtraman.2020.101819
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Heat, Hills and the High Season

Suzanne Maas / Paraskevas Nikolaou / Maria Attard / Loukas Dimitriou

Sustainability, Vol 13, Iss 3274, p

A Model-Based Comparative Analysis of Spatio-Temporal Factors Affecting Shared Bicycle Use in Three Southern European Islands

2021 Volume 3274

Abstract: Bicycle sharing systems (BSSs) have been implemented in cities worldwide in an attempt to promote cycling. Despite exhibiting characteristics considered to be barriers to cycling, such as hot summers, hilliness and car-oriented infrastructure, Southern ... ...

Abstract	Bicycle sharing systems (BSSs) have been implemented in cities worldwide in an attempt to promote cycling. Despite exhibiting characteristics considered to be barriers to cycling, such as hot summers, hilliness and car-oriented infrastructure, Southern European island cities and tourist destinations Limassol (Cyprus), Las Palmas de Gran Canaria (Canary Islands, Spain) and the Valletta conurbation (Malta) are all experiencing the implementation of BSSs and policies to promote cycling. In this study, a year of trip data and secondary datasets are used to analyze dock-based BSS usage in the three case-study cities. How land use, socio-economic, network and temporal factors influence BSS use at station locations, both as an origin and as a destination, was examined using bivariate correlation analysis and through the development of linear mixed models for each case study. Bivariate correlations showed significant positive associations with the number of cafes and restaurants, vicinity to the beach or promenade and the percentage of foreign population at the BSS station locations in all cities. A positive relation with cycling infrastructure was evident in Limassol and Las Palmas de Gran Canaria, but not in Malta, as no cycling infrastructure is present in the island’s conurbation, where the BSS is primarily operational. Elevation had a negative association with BSS use in all three cities. In Limassol and Malta, where seasonality in weather patterns is strongest, a negative effect of rainfall and a positive effect of higher temperature were observed. Although there was a positive association between BSS use and the number of visiting tourists in Limassol and Malta, this is predominantly explained through the multi-collinearity with weather factors rather than by intensive use of the BSS by tourists. The linear mixed models showed more fine-grained results and explained differences in BSS use at stations, including differences for station use as an origin and as a destination. The insights from the correlation ...
Keywords	bicycle sharing systems (BSSs) ; cycling ; linear mixed models ; Southern Europe ; island cities ; Environmental effects of industries and plants ; TD194-195 ; Renewable energy sources ; TJ807-830 ; Environmental sciences ; GE1-350
Subject code	910
Language	English
Publishing date	2021-03-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Trip and Personal Characteristics towards the Intention to Cycle in Larnaca, Cyprus

Paraskevas Nikolaou / Socrates Basbas / Ioannis Politis / Georgios Borg

Sustainability, Vol 12, Iss 4250, p

An EFA-SEM Approach

2020 Volume 4250

Abstract: Mobility is one of the most important and challenging aspects that influence climate change, air quality, and especially the quality of citizens’ lives. Therefore, creating sustainable transport solutions makes way for different modes of transport such ... ...

Abstract	Mobility is one of the most important and challenging aspects that influence climate change, air quality, and especially the quality of citizens’ lives. Therefore, creating sustainable transport solutions makes way for different modes of transport such as the bicycle, which is continuously gaining more supporters, due to the health, economic, and environmental benefits that it provides. However, cyclists are facing several barriers (e.g., lack of infrastructure), a fact that keeps away commuters from using a bicycle for their daily trips. Investigating the factors that reflect on the commuters’ intention to use a bicycle is a sine qua non for the promotion of sustainable mobility. Therefore, the objective of this paper is the investigation of the factors that prevent residents with low experience or with no cultural/lifestyle background in regards to cycling from cycling. The case study of the city of Larnaca (Cyprus) is deployed by exploring the socio-demographic and trip characteristics of the city’s residents and their relation with the intention to cycle. A two-step approach is developed, namely Explanatory Factor Analysis (EFA) and Structural Equation Modeling (SEM). Despite the promotion of cycling that education is attempting to do (successfully), other factors (such as age, distance, and time) appear to prevent Larnaca’s residents from cycling. Among the actions that local authorities should undertake is that of safety prevention of the vulnerable users of the road network. This group includes elderly people, who need major encouraging interventions by local policymakers and stakeholders.
Keywords	exploratory factor analysis ; structural equation modeling ; intention ; bicycle ; sustainable mobility ; Environmental effects of industries and plants ; TD194-195 ; Renewable energy sources ; TJ807-830 ; Environmental sciences ; GE1-350
Subject code	710
Language	English
Publishing date	2020-05-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Identification of critical airports for controlling global infectious disease outbreaks: Stress-tests focusing in Europe

Nikolaou, Paraskevas / Dimitriou, Loukas

J Air Transp Manag

Abstract	As the global population increases and transportation connectivity improves in quality and prices, the demand for mobility increases, especially in long-haul services. According to the 2017 report of the European Commission in Mobility and Transport, the performance of all modes for passenger transport (roadways and airways) are reaching record highs. Although the benefits of the increased demand for mobility are substantial and welcome, an effort should be paid such as to ameliorate possible threatening side-effects that may also arise. As World Health Organization (WHO) denotes and as has been evident from the global COVID-19 epidemic outbreak, infectious diseases can be spread directly or indirectly from one person to another under common exposure circumstances such as air transportation (especially long-haul airline connections) that may act as the medium for transmitting and spreading infectious diseases. In this paper, analytical and realistic models have been integrated, for providing evidence on the spread dynamics of infectious diseases that may face Europe through the airlines system. In particular, a detailed epidemiological model has been integrated with the airlines' and land transport network, able to simulate the epidemic spread of infectious diseases originated from distant locations. Additionally, a wide set of experiments and simulations have been conducted, providing results from detailed stress-tests covering both mild as well as aggressive cases of epidemic spreading scenarios. The results provide convincing evidence on the effectiveness that the European airports' system offer in controlling the emergence of epidemics, but also on the time and extent that controlling measures should be taken in order to break the chain of infections in realistic cases.
Keywords	covid19
Publisher	WHO
Document type	Article
Note	WHO #Covidence: #343020
Database	COVID19

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Book ; Online: Fessonia

Chatzithanos, Paraskevas / Nikolaou, Grigoris / Stolkin, Rustam / Chiou, Manolis

a Method for Real-Time Estimation of Human Operator Workload Using Behavioural Entropy

2021

Abstract: This paper addresses the problem of the human operator cognitive workload estimation while controlling a robot. Being capable of assessing, in real-time, the operator's workload could help prevent calamitous events from occurring. This workload ... ...

Abstract	This paper addresses the problem of the human operator cognitive workload estimation while controlling a robot. Being capable of assessing, in real-time, the operator's workload could help prevent calamitous events from occurring. This workload estimation could enable an AI to make informed decisions to assist or advise the operator, in an advanced human-robot interaction framework. We propose a method, named Fessonia, for real-time cognitive workload estimation from multiple parameters of an operator's driving behaviour via the use of behavioural entropy. Fessonia is comprised of: a method to calculate the entropy (i.e. unpredictability) of the operator driving behaviour profile; the Driver Profile Update algorithm which adapts the entropy calculations to the evolving driving profile of individual operators; and a Warning And Indication System that uses workload estimations to issue advice to the operator. Fessonia is evaluated in a robot teleoperation scenario that incorporated cognitively demanding secondary tasks to induce varying degrees of workload. The results demonstrate the ability of Fessonia to estimate different levels of imposed workload. Additionally, it is demonstrated that our approach is able to detect and adapt to the evolving driving profile of the different operators. Lastly, based on data obtained, a decrease in entropy is observed when a warning indication is issued, suggesting a more attentive approach focused on the primary navigation task.
Keywords	Computer Science - Robotics
Subject code	629
Publishing date	2021-10-05
Publishing country	us
Document type	Book ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Exploring the temporal stability of global road safety statistics.

Dimitriou, Loukas / Nikolaou, Paraskevas / Antoniou, Constantinos

Accident; analysis and prevention

2018 Volume 130, Page(s) 38–53

Abstract: Given the importance of rigorous quantitative reasoning in supporting national, regional or global road safety policies, data quality, reliability, and stability are of the upmost importance. This study focuses on macroscopic properties of road safety ... ...

Abstract	Given the importance of rigorous quantitative reasoning in supporting national, regional or global road safety policies, data quality, reliability, and stability are of the upmost importance. This study focuses on macroscopic properties of road safety statistics and the temporal stability of these statistics at a global level. A thorough investigation of two years of measurements was conducted to identify any unexpected gaps that could highlight the existence of inconsistent measurements. The database used in this research includes 121 member countries of the United Nation (UN-121) with a population of at least one million (smaller country data shows higher instability) and includes road safety and socioeconomic variables collected from a number of international databases (e.g. WHO and World Bank) for the years 2010 and 2013. For the fulfillment of the earlier stated goal, a number of data visualization and exploratory analyses (Hierarchical Clustering and Principal Component Analysis) were conducted. Furthermore, in order to provide a richer analysis of the data, we developed and compared the specification of a number of Structural Equation Models for the years 2010 and 2013. Different scenarios have been developed, with different endogenous variables (indicators of mortality rate and fatality risk) and structural forms. The findings of the current research indicate inconsistency phenomena in global statistics of different instances/years. Finally, the results of this research provide evidence on the importance of careful and systematic data collection for developing advanced statistical and econometric techniques and furthermore for developing road safety policies.
MeSH term(s)	Accidents, Traffic/statistics & numerical data ; Data Accuracy ; Databases, Factual ; Humans ; Policy ; Reproducibility of Results ; Safety/statistics & numerical data ; Spatial Analysis
Language	English
Publishing date	2018-02-21
Publishing country	England
Document type	Journal Article
ZDB-ID	210223-7
ISSN	1879-2057 ; 0001-4575
ISSN (online)	1879-2057
ISSN	0001-4575
DOI	10.1016/j.aap.2017.12.015
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Zs.A 2461: Show issues

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Article ; Online: Screening for peripheral artery disease in dialysis patients: an opportunity for early disease detection and timely initiation of appropriate therapeutic measures.

Paraskevas, Kosmas I / Koupidis, Sotirios A / Tzovaras, Alexandros A / Nikolaou, Achilleas / Mikhailidis, Dimitri P

International urology and nephrology

2011 Volume 43, Issue 1, Page(s) 143–145

MeSH term(s)	Global Health ; Humans ; Incidence ; Kidney Failure, Chronic/complications ; Kidney Failure, Chronic/mortality ; Kidney Failure, Chronic/therapy ; Peripheral Arterial Disease/diagnosis ; Peripheral Arterial Disease/epidemiology ; Peripheral Arterial Disease/etiology ; Renal Dialysis ; Survival Rate
Language	English
Publishing date	2011-01-06
Publishing country	Netherlands
Document type	Editorial
ZDB-ID	204048-7
ISSN	1573-2584 ; 0301-1623 ; 0042-1162
ISSN (online)	1573-2584
ISSN	0301-1623 ; 0042-1162
DOI	10.1007/s11255-010-9892-7
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Zs.A 733: Show issues

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Article: The deceptive clinical picture of primary saphenofemoral junction aneurysms.

Liapis, C D / Paraskevas, K I / Nikolaou, A C / Kostakis, A G

International angiology : a journal of the International Union of Angiology

2005 Volume 24, Issue 2, Page(s) 193–195

Abstract: Venous aneurysms may remain undetected for years due to their obscure and non-specific clinical picture. Two cases of primary saphenofemoral junction aneurysm are described, and their vague clinical picture is highlighted. The importance of increased ... ...

Abstract	Venous aneurysms may remain undetected for years due to their obscure and non-specific clinical picture. Two cases of primary saphenofemoral junction aneurysm are described, and their vague clinical picture is highlighted. The importance of increased alertness and suspicion is noted, because of the gravity of the possible complications of an undetected venous aneurysm, namely rupture of the aneurysm and/or recurrent pulmonary embolism.
MeSH term(s)	Aged ; Aneurysm/diagnosis ; Female ; Femoral Vein ; Humans ; Middle Aged ; Saphenous Vein
Language	English
Publishing date	2005-06
Publishing country	Italy
Document type	Case Reports ; Journal Article
ZDB-ID	604910-2
ISSN	0392-9590
ISSN	0392-9590
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Zs.A 1833: Show issues

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Article: Circulating interleukin-15 in dementia disorders.

Rentzos, Michael / Paraskevas, George P / Kapaki, Elisabeth / Nikolaou, Chryssoula / Zoga, Margarita / Tsoutsou, Anthousa / Rombos, Antonis / Vassilopoulos, Demetrios

The Journal of neuropsychiatry and clinical neurosciences

2007 Volume 19, Issue 3, Page(s) 318–325

Abstract: The objective of this study was to assess the role of interleukin-15 (IL-15) as a potential marker of immune reactions in patients with Alzheimer's disease and vascular dementia. The authors measured by immunoassay serum IL-15 levels in 20 patients with ... ...

Abstract	The objective of this study was to assess the role of interleukin-15 (IL-15) as a potential marker of immune reactions in patients with Alzheimer's disease and vascular dementia. The authors measured by immunoassay serum IL-15 levels in 20 patients with Alzheimer's disease and 15 patients with vascular dementia and compared them with serum IL-15 levels in 15 healthy subjects. The authors also studied the effect of treatment with acetylcholinesterase inhibitors (AChEI) on serum IL-15 levels. Patients with Alzheimer's disease were found to have significantly lower serum IL-15 levels compared with healthy subjects and patients with vascular dementia. Healthy subjects and patients with vascular dementia did not differ between each other. Age, sex, disease duration, and Mini-Mental State Examination score did not affect IL-15 levels in any of the groups. Treatment with AChEI had no influence on IL-15 concentrations. The findings suggest that IL-15 is not implicated in the pathogenetic mechanisms of Alzheimer's disease and vascular dementia. An immune hyporesponsiveness at some point during disease development may be responsible for the lower levels of IL-15 and other cytokines in Alzheimer's disease patients.
MeSH term(s)	Aged ; Aged, 80 and over ; Analysis of Variance ; Cholinesterase Inhibitors/therapeutic use ; Dementia/blood ; Dementia/classification ; Dementia/drug therapy ; Enzyme-Linked Immunosorbent Assay/methods ; Female ; Humans ; Interleukin-15/blood ; Male ; Mental Status Schedule/statistics & numerical data ; Middle Aged ; Neuropsychological Tests/statistics & numerical data ; Statistics, Nonparametric
Chemical Substances	Cholinesterase Inhibitors ; Interleukin-15
Language	English
Publishing date	2007
Publishing country	United States
Document type	Clinical Trial ; Journal Article
ZDB-ID	1036340-3
ISSN	1545-7222 ; 0895-0172
ISSN (online)	1545-7222
ISSN	0895-0172
DOI	10.1176/jnp.2007.19.3.318
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Zs.A 2633: Show issues

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Article: External Iliac artery stent mucormycosis in a renal transplant patient.

Liapis, Christos D / Petrikkos, Georgios L / Paraskevas, Kosmas I / Skiada, Anna / Nikolaou, Alex C / Tzortzis, Giorgos / Kostakis, Alkiviadis G

Annals of vascular surgery

2006 Volume 20, Issue 2, Page(s) 253–257

Abstract: A Mucorales infection of an external iliac artery stent in a renal transplant patient is described. Following a kidney transplantation operation and an acute rejection of the transplant, an aneurysm developed at the site of the arterial ligation and ... ...

Abstract	A Mucorales infection of an external iliac artery stent in a renal transplant patient is described. Following a kidney transplantation operation and an acute rejection of the transplant, an aneurysm developed at the site of the arterial ligation and three stents were inserted. Two months following insertion of the stents, recurrent episodes of peripheral thromboembolism occurred. Histological examination of the thrombus revealed hyphae characteristic of mucormycosis. A combination of surgical and medical treatment with intravenous liposomal amphotericin B was applied, which led to complete cure of the disease without infection recurrence after 1 year of follow-up.
MeSH term(s)	Acute Kidney Injury/surgery ; Adult ; Amphotericin B/therapeutic use ; Aneurysm, False/surgery ; Angioplasty ; Antifungal Agents/therapeutic use ; Graft Rejection ; Humans ; Iliac Aneurysm/surgery ; Kidney Transplantation ; Male ; Mucormycosis/drug therapy ; Prosthesis-Related Infections/drug therapy ; Stents/adverse effects ; Treatment Outcome
Chemical Substances	Antifungal Agents ; Amphotericin B (7XU7A7DROE)
Language	English
Publishing date	2006-03
Publishing country	Netherlands
Document type	Case Reports ; Journal Article
ZDB-ID	1027366-9
ISSN	1615-5947 ; 0890-5096
ISSN (online)	1615-5947
ISSN	0890-5096
DOI	10.1007/s10016-006-9007-1
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