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  1. Book: Xiao er xue yi bing xue

    Qin, Zhenting

    1982  

    Author's details Qin Zhenting zhu bian ; Wang Ruwen fu zhu bian
    MeSH term(s) Hematologic Diseases ; Child ; Infant
    Language Chinese
    Size 3, 799 p., [8] p. of plates :, ill.
    Edition Di 2 ban.
    Publisher Shanghai ke xue ji shu chu ban she : Xin hua shu dian Shanghai fa xing suo fa xing
    Publishing place Shanghai
    Document type Book
    Database Catalogue of the US National Library of Medicine (NLM)

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  2. Book: Xiao er xue ye bing xue

    Qin, Zhenting

    [Blood diseases in children

    (Yi shi jin xiu cong shu)

    1965  

    Series title Yi shi jin xiu cong shu
    MeSH term(s) Hematologic Diseases ; Child ; Infant
    Language Chinese
    Size 2, 4, 494 p., illus.
    Publisher Shanghai ke xue ji shu chu ban she
    Publishing place Shanghai
    Document type Book
    Database Catalogue of the US National Library of Medicine (NLM)

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  3. Book: Nei fen mi dai xie bing Zhong yi zhi liao xue

    Huang, Taikang / Sun, Qin'guo / Liu, Xueyue

    (Xian dai Zhong yi xi lie cong shu ; 18)

    2002  

    Title variant Therapeutics of TCM on endocrine and metabolism disease
    Author's details zong bian Huang Taikang ; zhu bian Sun Qin'guo, Liu Xueyue
    Series title Xian dai Zhong yi xi lie cong shu ; 18
    MeSH term(s) Endocrine System Diseases/therapy ; Medicine, Chinese Traditional ; Metabolic Diseases/therapy
    Language Chinese ; English
    Size 5, 699 p. ;, 31 cm.
    Edition Di 1 ban.
    Publisher Zhongguo yi yao ke ji chu ban she
    Publishing place Beijing Shi
    Document type Book
    Note Abstract also in English.
    ISBN 9787506725859 ; 7506725851
    Database Catalogue of the US National Library of Medicine (NLM)

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  4. Book: Xue hong dan bai bing

    Qin, Wenbin

    1984  

    Author's details Qin Wenbin bian zhu
    MeSH term(s) Hemoglobinopathies
    Language Chinese
    Size 10, 317 p. :, ill.
    Edition Di 1 ban.
    Publisher Ren min wei sheng chu ban she : Xin hua shu dian Beijing fa xing suo fa xing
    Publishing place Beijing Shi
    Document type Book
    Database Catalogue of the US National Library of Medicine (NLM)

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  5. Article ; Online: Rapid Nucleic Acid Detection of

    Yang, Yujuan / Kong, Xiangxiang / Yang, Jielin / Xue, Junxin / Niu, Bing / Chen, Qin

    International journal of molecular sciences

    2024  Volume 25, Issue 6

    Abstract: ... Listeria ... ...

    Abstract Listeria monocytogenes
    MeSH term(s) Animals ; Cattle ; Humans ; Listeria monocytogenes/genetics ; CRISPR-Cas Systems ; Food Microbiology ; Nucleic Acid Amplification Techniques/methods ; Recombinases/genetics ; DNA
    Chemical Substances Recombinases ; DNA (9007-49-2)
    Language English
    Publishing date 2024-03-20
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms25063477
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: A Pilot Study on a Possible Mechanism behind Olfactory Dysfunction in Parkinson's Disease: The Association of TAAR1 Downregulation with Neuronal Loss and Inflammation along Olfactory Pathway.

    Zhang, Mei-Xuan / Hong, Hui / Shi, Yun / Huang, Wen-Yan / Xia, Yi-Meng / Tan, Lu-Lu / Zhao, Wei-Jiang / Qiao, Chen-Meng / Wu, Jian / Zhao, Li-Ping / Huang, Shu-Bing / Jia, Xue-Bing / Shen, Yan-Qin / Cui, Chun

    Brain sciences

    2024  Volume 14, Issue 4

    Abstract: Parkinson's disease (PD) is characterized not only by motor symptoms but also by non-motor dysfunctions, such as olfactory impairment; the cause is not fully understood. Our study suggests that neuronal loss and inflammation in brain regions along the ... ...

    Abstract Parkinson's disease (PD) is characterized not only by motor symptoms but also by non-motor dysfunctions, such as olfactory impairment; the cause is not fully understood. Our study suggests that neuronal loss and inflammation in brain regions along the olfactory pathway, such as the olfactory bulb (OB) and the piriform cortex (PC), may contribute to olfactory dysfunction in PD mice, which might be related to the downregulation of the trace amine-associated receptor 1 (TAAR1) in these areas. In the striatum, although only a decrease in mRNA level, but not in protein level, of TAAR1 was detected, bioinformatic analyses substantiated its correlation with PD. Moreover, we discovered that neuronal death and inflammation in the OB and the PC in PD mice might be regulated by TAAR through the Bcl-2/caspase3 pathway. This manifested as a decrease of anti-apoptotic protein Bcl-2 and an increase of the pro-apoptotic protein cleaved caspase3, or through regulating astrocytes activity, manifested as the increase of TAAR1 in astrocytes, which might lead to the decreased clearance of glutamate and consequent neurotoxicity. In summary, we have identified a possible mechanism to elucidate the olfactory dysfunction in PD, positing neuronal damage and inflammation due to apoptosis and astrocyte activity along the olfactory pathway in conjunction with the downregulation of TAAR1.
    Language English
    Publishing date 2024-03-22
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2651993-8
    ISSN 2076-3425
    ISSN 2076-3425
    DOI 10.3390/brainsci14040300
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Book: Bing li jie pou xue ge lun

    Liang, Boqiang / Qin, Guangyu

    [Treatises in pathological anatomy, by Qin Guangyu et al.]

    1964  

    Title translation Treatises in pathological anatomy, by Ch'in Kuang-yü et al.
    MeSH term(s) Pathology
    Language Chinese
    Size 8, 375 p., illus.
    Edition Rev. ed.
    Publisher Ren min wei sheng chu ban she
    Publishing place Peking
    Document type Book
    Database Catalogue of the US National Library of Medicine (NLM)

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  8. Article ; Online: Deep learning for head and neck semi-supervised semantic segmentation.

    Luan, Shunyao / Ding, Yi / Shao, Jiakang / Zou, Bing / Yu, Xiao / Qin, Nannan / Zhu, Benpeng / Wei, Wei / Xue, Xudong

    Physics in medicine and biology

    2024  Volume 69, Issue 5

    Abstract: ... ...

    Abstract Objective
    MeSH term(s) Humans ; Deep Learning ; Semantics ; Tomography, X-Ray Computed ; Head and Neck Neoplasms/diagnostic imaging ; Head and Neck Neoplasms/radiotherapy ; Organs at Risk ; Image Processing, Computer-Assisted/methods
    Language English
    Publishing date 2024-02-19
    Publishing country England
    Document type Journal Article
    ZDB-ID 208857-5
    ISSN 1361-6560 ; 0031-9155
    ISSN (online) 1361-6560
    ISSN 0031-9155
    DOI 10.1088/1361-6560/ad25c2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 199: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  9. Article ; Online: Genomic analysis of Marinimicrobium sp. C6131 reveals its genetic potential involved in chitin metabolism.

    Dang, Yan-Ru / Zhang, Xiao-Yu / Liu, Sha-Sha / Li, Ping-Yi / Ren, Xue-Bing / Qin, Qi-Long

    Marine genomics

    2022  Volume 67, Page(s) 101007

    Abstract: Marinimicrobium sp. C6131, which had the ability to degrade chitin, was isolated from deep-sea sediment of the southwest Indian Ocean. Here, the genome of strain C6131 was sequenced and the chitin metabolic pathways were constructed. The genome contained ...

    Abstract Marinimicrobium sp. C6131, which had the ability to degrade chitin, was isolated from deep-sea sediment of the southwest Indian Ocean. Here, the genome of strain C6131 was sequenced and the chitin metabolic pathways were constructed. The genome contained a circular chromosome of 4,207,651 bp with a G + C content of 58.50%. A total of 3471 protein-coding sequences were predicted. Gene annotation and metabolic pathway reconstruction showed that strain C6131 possessed genes and two metabolic pathways involved in chitin catabolism: the hydrolytic chitin utilization pathway initiated by chitinases and the oxidative chitin utilization pathway initiated by lytic polysaccharide monooxygenases. Chitin is the most abundant polysaccharide in the ocean. Degradation and recycling of chitin driven by marine bacteria are crucial for biogeochemical cycles of carbon and nitrogen in the ocean. The genomic information of strain C6131 revealed its genetic potential involved in chitin metabolism. The strain C6131 could grow with colloidal chitin as the sole carbon source, indicating that these genes would have functions in chitin degradation and utilization. The genomic sequence of Marinimicrobium sp. C6131 could provide fundamental information for future studies on chitin degradation, and help to improve our understanding of the chitin degradation process in deep-sea environments.
    MeSH term(s) Gammaproteobacteria ; Genome, Bacterial ; Genomics ; Chitin/metabolism ; Carbon
    Chemical Substances Chitin (1398-61-4) ; Carbon (7440-44-0)
    Language English
    Publishing date 2022-12-14
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2429626-0
    ISSN 1876-7478 ; 1874-7787
    ISSN (online) 1876-7478
    ISSN 1874-7787
    DOI 10.1016/j.margen.2022.101007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Ecological function and interaction of different bacterial groups during alginate processing in coastal seawater community

    Qian-Qian Cha / Sha-Sha Liu / Yan-Ru Dang / Xue-Bing Ren / Fei Xu / Ping-Yi Li / Xiu-Lan Chen / Peng Wang / Xi-Ying Zhang / Yu-Zhong Zhang / Qi-Long Qin

    Environment International, Vol 182, Iss , Pp 108325- (2023)

    2023  

    Abstract: The degradation of high molecular weight organic matter (HMWOM) is a core process of oceanic carbon cycle, which is determined by the activity of microbial communities harboring hundreds of different species. Illustrating the active microbes and their ... ...

    Abstract The degradation of high molecular weight organic matter (HMWOM) is a core process of oceanic carbon cycle, which is determined by the activity of microbial communities harboring hundreds of different species. Illustrating the active microbes and their interactions during HMWOM processing can provide key information for revealing the relationship between community composition and its ecological functions. In this study, the genomic and transcriptional responses of microbial communities to the availability of alginate, an abundant HMWOM in coastal ecosystem, were elucidated. The main degraders transcribing alginate lyase (Aly) genes came from genera Alteromonas, Psychrosphaera and Colwellia. Meanwhile, some strains, mainly from the Rhodobacteraceae family, did not transcribe Aly gene but could utilize monosaccharides to grow. The co-culture experiment showed that the activity of Aly-producing strain could promote the growth of Aly-non-producing strain when alginate was the sole carbon source. Interestingly, this interaction did not reduce the alginate degradation rate, possibly due to the easily degradable nature of alginate. This study can improve our understanding of the relationship between microbial community activity and alginate metabolism function as well as further manipulation of microbial community structure for alginate processing.
    Keywords Environmental sciences ; GE1-350
    Language English
    Publishing date 2023-12-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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