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  1. Article: Hepatic Epstein-Barr Virus-Associated Smooth Muscle Tumor in a Heart and Liver Transplant Recipient.

    Johnson, Brett M / Iskandar, Jean-Pierre / Farha, Natalie / Yerian, Lisa / Modaresi Esfeh, Jamak / Lindenmeyer, Christina

    ACG case reports journal

    2022  Volume 9, Issue 6, Page(s) e00782

    Abstract: Epstein-Barr virus (EBV)-associated smooth muscle tumors (SMT) have been described in immunosuppressed states, including in post-transplant patients. Here, we discuss a heart-liver transplant recipient who was found to have multifocal hepatic EBV-SMT. ... ...

    Abstract Epstein-Barr virus (EBV)-associated smooth muscle tumors (SMT) have been described in immunosuppressed states, including in post-transplant patients. Here, we discuss a heart-liver transplant recipient who was found to have multifocal hepatic EBV-SMT. His immunosuppression was initially transitioned from tacrolimus to sirolimus because of the proposed benefits of the mechanistic target of rapamycin inhibitors on EBV-SMT. Unfortunately, he suffered acute rejection of his liver allograft while on sirolimus therapy, which ultimately led to consideration of retransplantation.
    Language English
    Publishing date 2022-06-06
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2814825-3
    ISSN 2326-3253
    ISSN 2326-3253
    DOI 10.14309/crj.0000000000000782
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Histopathological evaluation of fatty and alcoholic liver diseases.

    Yerian, Lisa

    Journal of digestive diseases

    2011  Volume 12, Issue 1, Page(s) 17–24

    Abstract: Fatty liver disease (FLD) represents a common form of hepatic dysfunction among adults and children. Recognition of steatosis is usually straightforward but the differential diagnosis is broad. Macrovesicular steatosis may occur due to alcohol use or ... ...

    Abstract Fatty liver disease (FLD) represents a common form of hepatic dysfunction among adults and children. Recognition of steatosis is usually straightforward but the differential diagnosis is broad. Macrovesicular steatosis may occur due to alcohol use or metabolic factors including obesity and hyperinsulinemia. Steatosis is, in some patients, accompanied by varying degrees of inflammation, ballooning hepatocyte degeneration or fibrosis, or both. The pathologist's recognition and interpretation of these features, when present, is critical for the classification and prognostication of the disease. Recent advances in the study of FLD have yielded new information for the surgical pathologist to guide the interpretation of steatosis in children and adults, and in patients with other forms of liver disease such as chronic viral hepatitis. This article details the current terminology for various forms of FLD, highlights the key histological features and reviews recent advances in the field.
    MeSH term(s) Diagnosis, Differential ; Fatty Liver, Alcoholic/classification ; Fatty Liver, Alcoholic/pathology ; Humans ; Liver/pathology ; Pathology, Clinical
    Language English
    Publishing date 2011-02
    Publishing country Australia
    Document type Journal Article ; Review
    ZDB-ID 2317117-0
    ISSN 1751-2980 ; 1751-2972
    ISSN (online) 1751-2980
    ISSN 1751-2972
    DOI 10.1111/j.1751-2980.2010.00472.x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Histology of metaplasia and dysplasia in Barrett's esophagus.

    Yerian, Lisa

    Surgical oncology clinics of North America

    2009  Volume 18, Issue 3, Page(s) 411–422

    Abstract: The histologic diagnosis of Barrett's dysplasia requires the identification of intestinal metaplasia, which often presents a challenge due to sampling error, observer variation, and difficulty in histologic interpretation. Particularly problematic is the ...

    Abstract The histologic diagnosis of Barrett's dysplasia requires the identification of intestinal metaplasia, which often presents a challenge due to sampling error, observer variation, and difficulty in histologic interpretation. Particularly problematic is the separation of negative, indefinite, and low-grade dysplasia, the varied histological appearances of high-grade dysplasia, and the diagnosis of suboptimal biopsy material. This article seeks to aid in the histological evaluation of metaplasia and dysplasia in Barrett's esophagus.
    MeSH term(s) Adenocarcinoma/etiology ; Barrett Esophagus/complications ; Barrett Esophagus/pathology ; Biopsy ; Cell Transformation, Neoplastic/pathology ; Diagnosis, Differential ; Esophageal Neoplasms/etiology ; Esophagus/pathology ; Gastroesophageal Reflux/complications ; Goblet Cells/pathology ; Histocytochemistry ; Histological Techniques/methods ; Histological Techniques/standards ; Humans ; Metaplasia ; Neoplasm Staging ; Observer Variation ; Precancerous Conditions/complications ; Precancerous Conditions/pathology ; Selection Bias ; Severity of Illness Index
    Language English
    Publishing date 2009-07
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1196919-2
    ISSN 1558-5042 ; 1055-3207
    ISSN (online) 1558-5042
    ISSN 1055-3207
    DOI 10.1016/j.soc.2009.03.011
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Identifying activated hepatic stellate cells in chronic and posttransplant recurrent hepatitis C.

    Yerian, Lisa

    Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society

    2008  Volume 14, Issue 6, Page(s) 756–758

    MeSH term(s) Animals ; Biopsy ; Fibrosis ; Glial Fibrillary Acidic Protein/metabolism ; Hepatitis C/diagnosis ; Hepatitis C/etiology ; Humans ; Liver/cytology ; Liver/pathology ; Liver/virology ; Liver Transplantation/adverse effects ; Postoperative Period ; Rats ; Research Design ; Retrospective Studies
    Chemical Substances Glial Fibrillary Acidic Protein
    Language English
    Publishing date 2008-06
    Publishing country United States
    Document type Comment ; Editorial
    ZDB-ID 2006866-9
    ISSN 1527-6473 ; 1527-6465
    ISSN (online) 1527-6473
    ISSN 1527-6465
    DOI 10.1002/lt.21469
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Evolution of nonalcoholic fatty liver disease recurrence after liver transplantation.

    Patil, Deepa T / Yerian, Lisa M

    Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society

    2012  Volume 18, Issue 10, Page(s) 1147–1153

    Abstract: Nonalcoholic steatohepatitis (NASH) is the progressive form of nonalcoholic fatty liver disease (NAFLD) and is the fourth most common indication for liver transplantation. Risk factors for NAFLD can persist and even worsen after liver transplantation. ... ...

    Abstract Nonalcoholic steatohepatitis (NASH) is the progressive form of nonalcoholic fatty liver disease (NAFLD) and is the fourth most common indication for liver transplantation. Risk factors for NAFLD can persist and even worsen after liver transplantation. However, the risk and significance of NAFLD recurrence remain unclear. Reported posttransplant NAFLD and NASH recurrence rates vary widely across studies. There is little information detailing the histological evolution of NAFLD recurrence, and the long-term natural history of NAFLD recurrence is unclear. In this review, we summarize the findings of studies on the prevalence of recurrent NAFLD and its risk factors in the posttransplant setting, and we explore reasons for the discrepant reported recurrence rates. On the basis of currently available data, the relatively low rates of advanced fibrosis and NAFLD-associated graft loss and the comparability of the survival rates for these patients and patients undergoing transplantation for other diseases suggest that although NAFLD or NASH can recur, the clinical significance of disease recurrence for graft or patient survival may be small.
    MeSH term(s) Fatty Liver/epidemiology ; Fatty Liver/mortality ; Fatty Liver/pathology ; Humans ; Liver Transplantation ; Non-alcoholic Fatty Liver Disease ; Postoperative Period ; Prevalence ; Recurrence ; Risk Factors ; Survival Rate
    Language English
    Publishing date 2012-10
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2006866-9
    ISSN 1527-6473 ; 1527-6465
    ISSN (online) 1527-6473
    ISSN 1527-6465
    DOI 10.1002/lt.23499
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Pancreas transplant: recent advances and spectrum of features in pancreas allograft pathology.

    Patil, Deepa T / Yerian, Lisa M

    Advances in anatomic pathology

    2010  Volume 17, Issue 3, Page(s) 202–208

    Abstract: As result of improved surgical techniques and newer immunosuppressive regimens contributing significantly to better graft survival, exocrine pancreas transplantation remains the standard treatment of choice for patients with diabetes mellitus complicated ...

    Abstract As result of improved surgical techniques and newer immunosuppressive regimens contributing significantly to better graft survival, exocrine pancreas transplantation remains the standard treatment of choice for patients with diabetes mellitus complicated by end-stage renal disease. Histologic assessment continues to play an important role in the diagnosis of graft complications after pancreas transplantation, especially for evaluating allograft rejection where histopathology is still considered the gold standard. This review elaborates on the current types of pancreas transplants and focuses on the patterns of allograft injury that are encountered in posttransplantation pancreas biopsies along with the pertinent differential diagnoses. In addition to optimal histologic assessment, as in any other organ transplant setting, clinical information including indication and duration of transplant as well as other serologic work-up must be taken into consideration during clinical decision making for optimal graft outcome.
    MeSH term(s) Graft Rejection/pathology ; Humans ; Pancreas/pathology ; Pancreas Transplantation/pathology ; Transplantation, Homologous
    Language English
    Publishing date 2010-05
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1212493-x
    ISSN 1533-4031 ; 1072-4109
    ISSN (online) 1533-4031
    ISSN 1072-4109
    DOI 10.1097/PAP.0b013e3181d97635
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: In Response.

    Dasarathy, Srinivasan / Dasarathy, Jaividhya / Khiyami, Amer / Yerian, Lisa / McCullough, Arthur J

    Journal of clinical gastroenterology

    2016  Volume 50, Issue 2, Page(s) 181

    MeSH term(s) Diabetes Mellitus/drug therapy ; Docosahexaenoic Acids/therapeutic use ; Eicosapentaenoic Acid/therapeutic use ; Female ; Humans ; Male ; Non-alcoholic Fatty Liver Disease/drug therapy
    Chemical Substances Docosahexaenoic Acids (25167-62-8) ; Eicosapentaenoic Acid (AAN7QOV9EA)
    Language English
    Publishing date 2016-02
    Publishing country United States
    Document type Comment ; Letter ; Research Support, N.I.H., Extramural
    ZDB-ID 448460-5
    ISSN 1539-2031 ; 0192-0790
    ISSN (online) 1539-2031
    ISSN 0192-0790
    DOI 10.1097/MCG.0000000000000451
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Iron ulcers.

    Parsi, Mansour A / Yerian, Lisa M

    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association

    2009  Volume 7, Issue 10, Page(s) A22

    MeSH term(s) Aged, 80 and over ; Endoscopy, Digestive System ; Female ; Gastric Mucosa/pathology ; Helicobacter Infections/diagnosis ; Helicobacter Infections/microbiology ; Helicobacter pylori/isolation & purification ; Histocytochemistry ; Humans ; Iron/toxicity ; Stomach Diseases/chemically induced ; Stomach Diseases/pathology ; Ulcer/chemically induced ; Ulcer/pathology
    Chemical Substances Iron (E1UOL152H7)
    Language English
    Publishing date 2009-10
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 2119789-1
    ISSN 1542-7714 ; 1542-3565
    ISSN (online) 1542-7714
    ISSN 1542-3565
    DOI 10.1016/j.cgh.2009.01.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Diagnosing gastroesophageal reflux disease: the pathologist's perspective.

    Allende, Daniela S / Yerian, Lisa M

    Advances in anatomic pathology

    2009  Volume 16, Issue 3, Page(s) 161–165

    Abstract: Gastroesophageal reflux disease (GERD) is a common disease frequently encountered by surgical pathologists. Although the pathogenesis and clinical features of the disease have been studied for years, many unanswered questions remain. Typical clinical ... ...

    Abstract Gastroesophageal reflux disease (GERD) is a common disease frequently encountered by surgical pathologists. Although the pathogenesis and clinical features of the disease have been studied for years, many unanswered questions remain. Typical clinical symptoms along with the endoscopic findings, pH monitoring, and biopsies, all support the diagnosis. However, these tests may yield conflicting findings, and at present there is no gold standard for the diagnosis of GERD. In patients with normal or nearly normal endoscopic findings (nonerosive reflux disease), the major diagnostic burden lies with the histology. The histologic diagnosis of GERD is based on a combination of findings, including basal cell hyperplasia, papilla elongation, inflammation, and dilatation of intercellular spaces. However, these features exhibit varying sensitivity and specificity, and minimal biopsy criteria for the diagnosis of reflux esophagitis have not been rigorously tested in well-characterized patient populations. However, given the high prevalence of GERD, pathologists face esophageal mucosal biopsies daily and must recognize the diagnostic strengths and limitations of histologic features of reflux esophagitis. Future studies and new techniques may improve the diagnostic strength of histology and establish meaningful minimal criteria for the diagnosis of reflux esophagitis.
    MeSH term(s) Biopsy/methods ; Eosinophils/pathology ; Esophagoscopy ; Esophagus/immunology ; Esophagus/pathology ; Extracellular Space ; Gastroesophageal Reflux/pathology ; Humans ; Hyperplasia/pathology ; Neutrophils/pathology
    Language English
    Publishing date 2009-05
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1212493-x
    ISSN 1533-4031 ; 1072-4109
    ISSN (online) 1533-4031
    ISSN 1072-4109
    DOI 10.1097/PAP.0b013e3181a186a3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Book: Atlas of transplant pathology

    Cagle, Philip T / Yerian, Lisa / Truong, Luan D

    heart, kidney, liver, lung, pancreas

    2015  

    Institution College of American Pathologists,
    Author's details Philip T. Cagle, Lisa Yerian, Luan D. Truong, editors
    MeSH term(s) Organ Transplantation/adverse effects ; Transplants/pathology ; Postoperative Complications/pathology ; Transplantation Immunology
    Language English
    Size vii, 245 pages :, illustrations
    Document type Book
    ISBN 9780983706861 ; 0983706867
    Database Catalogue of the US National Library of Medicine (NLM)

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