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  1. Book: Thoracic tumors

    Lokuhetty, Dilani / White, Valeri A. / Cree, Ian A.

    (WHO Classification of Tumours ; 5)

    2021  

    Institution WHO / Classification of Tumours Editorial Board
    International Agency for Research on Cancer
    International Association for the Study of Lung Cancer
    ITMIG
    International Mesothelioma Panel
    Author's details edited by the WHO Classification of Tumours Editorial Board ; Dilani Lokuhetty, Valeri A. White, Ian A. Cree
    Series title WHO Classification of Tumours ; 5
    World Health Organization classification of tumours
    Collection World Health Organization classification of tumours
    Keywords Thoracic Neoplasms
    Language English
    Size XIII, 565 Seiten, Illustrationen (farbig)
    Edition [5. Auflage]
    Publisher International Agency for Research on Cancer, World Health Organization
    Publishing place Lyon Cedex
    Publishing country France
    Document type Book
    HBZ-ID HT020938359
    ISBN 978-92-832-4506-3 ; 92-832-4506-7
    Database Catalogue ZB MED Medicine, Health

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  2. Article ; Online: COVID-19 and ESRD: Entering a New Era of Uncertainty.

    Valeri, Anthony

    Kidney international reports

    2020  Volume 5, Issue 9, Page(s) 1381–1382

    Keywords covid19
    Language English
    Publishing date 2020-07-25
    Publishing country United States
    Document type Editorial ; Comment
    ISSN 2468-0249
    ISSN (online) 2468-0249
    DOI 10.1016/j.ekir.2020.07.020
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Vitamin Supplementation in ESKD: Too Little or Too Much of a Good Thing?

    Valeri, Anthony

    Kidney international reports

    2020  Volume 5, Issue 12, Page(s) 2125–2126

    Language English
    Publishing date 2020-09-28
    Publishing country United States
    Document type Editorial ; Comment
    ISSN 2468-0249
    ISSN (online) 2468-0249
    DOI 10.1016/j.ekir.2020.09.030
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: State of the Art and Future of Stem Cell Therapy in Ischemic Stroke: Why Don't We Focus on Their Administration?

    Valeri, Andrea / Mazzon, Emanuela

    Bioengineering (Basel, Switzerland)

    2023  Volume 10, Issue 1

    Abstract: Stroke is one of the leading causes of death and disability worldwide, so there is an urgent need to find a therapy for the tragic outcomes of this cerebrovascular disease. Stem cells appeared to be a good solution for many conditions, so different ... ...

    Abstract Stroke is one of the leading causes of death and disability worldwide, so there is an urgent need to find a therapy for the tragic outcomes of this cerebrovascular disease. Stem cells appeared to be a good solution for many conditions, so different experiments were made to establish stem cells as a feasible therapy for stroke. The aim of this review is to analyze the state of the art of stem cell therapy for stroke and if the route of administration could represent a valid adjusting point for ameliorating the therapy's outcome. To obtain this, we searched the scientific literature of the last 10 years for relevant in vitro and in vivo evidence regarding stem cells' potential in stroke therapy. In vitro evidence points to hypoxia, among the preconditioning strategies, as the most used and probably efficient method to enhance cells qualities, while in vivo results raise the question if it is the type of cells or how they are administrated which can make the difference in terms of efficiency. Unfortunately, despite the number of clinical trials, only a few were successfully concluded, demonstrating how urgent the necessity is to translate pre-clinical results into clinics. Since any type of stem cell seems suitable for therapy, the chosen route of administration corresponds to different engraftment rates, distribution and efficiency in terms of the beneficial effects of stem cells. Intravenous administration was widely used for delivering stem cells into the human body, but recently intranasal administration has given promising results in vivo. It allows stem cells to efficiently reach the brain that was precluded to intravenous administration, so it is worth further investigation.
    Language English
    Publishing date 2023-01-14
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2746191-9
    ISSN 2306-5354
    ISSN 2306-5354
    DOI 10.3390/bioengineering10010118
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Research on texture images and radiomics in urology: a review of urological MR imaging applications.

    Valeri, Antoine / Nguyen, Truong An

    Current opinion in urology

    2023  Volume 33, Issue 6, Page(s) 428–436

    Abstract: Purpose of review: Tumor volume and heterogenicity are associated with diagnosis and prognosis of urological cancers, and assessed by conventional imaging. Quantitative imaging, Radiomics, using advanced mathematical analysis may contain information ... ...

    Abstract Purpose of review: Tumor volume and heterogenicity are associated with diagnosis and prognosis of urological cancers, and assessed by conventional imaging. Quantitative imaging, Radiomics, using advanced mathematical analysis may contain information imperceptible to the human eye, and may identify imaging-based biomarkers, a new field of research for individualized medicine. This review summarizes the recent literature on radiomics in kidney and prostate cancers and the future perspectives.
    Recent findings: Radiomics studies have been developed and showed promising results in diagnosis, in characterization, prognosis, treatment planning and recurrence prediction in kidney tumors and prostate cancer, but its use in guiding clinical decision-making remains limited at present due to several limitations including lack of external validations in most studies, lack of prospective studies and technical standardization.
    Summary: Future challenges, besides developing prospective and validated studies, include automated segmentation using artificial intelligence deep learning networks and hybrid radiomics integrating clinical data, combining imaging modalities and genomic features. It is anticipated that these improvements may allow identify these noninvasive, imaging-based biomarkers, to enhance precise diagnosis, improve decision-making and guide tailored treatment.
    MeSH term(s) Humans ; Artificial Intelligence ; Urology ; Prospective Studies ; Magnetic Resonance Imaging ; Biomarkers
    Chemical Substances Biomarkers
    Language English
    Publishing date 2023-09-18
    Publishing country United States
    Document type Review ; Journal Article
    ZDB-ID 1091792-5
    ISSN 1473-6586 ; 0963-0643
    ISSN (online) 1473-6586
    ISSN 0963-0643
    DOI 10.1097/MOU.0000000000001131
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Methods for the Analysis of Multiple Epigenomic Mediators in Environmental Epidemiology.

    Domingo-Relloso, Arce / Tellez-Plaza, Maria / Valeri, Linda

    Current environmental health reports

    2024  

    Abstract: Purpose of review: Epigenetic changes can be highly influenced by environmental factors and have in turn been proposed to influence chronic disease. Being able to quantify to which extent epigenomic processes are mediators of the association between ... ...

    Abstract Purpose of review: Epigenetic changes can be highly influenced by environmental factors and have in turn been proposed to influence chronic disease. Being able to quantify to which extent epigenomic processes are mediators of the association between environmental exposures and diseases is of interest for epidemiologic research. In this review, we summarize the proposed mediation analysis methods with applications to epigenomic data.
    Recent findings: The ultra-high dimensionality and high correlations that characterize omics data have hindered the precise quantification of mediated effects. Several methods have been proposed to deal with mediation in high-dimensional settings, including methods that incorporate dimensionality reduction techniques to the mediation algorithm. Although important methodological advances have been conducted in the previous years, key challenges such as the development of sensitivity analyses, dealing with mediator-mediator interactions, including environmental mixtures as exposures, or the integration of different omic data should be the focus of future methodological developments for epigenomic mediation analysis.
    Language English
    Publishing date 2024-02-22
    Publishing country Switzerland
    Document type Journal Article ; Review
    ISSN 2196-5412
    ISSN (online) 2196-5412
    DOI 10.1007/s40572-024-00436-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: COVID-19 and ESRD

    Valeri, Anthony

    Kidney International Reports

    Entering a New Era of Uncertainty

    2020  Volume 5, Issue 9, Page(s) 1381–1382

    Keywords Nephrology ; covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    ISSN 2468-0249
    DOI 10.1016/j.ekir.2020.07.020
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Gaming bacterial metabolism.

    Valeri, Jacqueline A / Krishnan, Aarti / Collins, James J

    Nature microbiology

    2023  Volume 8, Issue 6, Page(s) 1004–1005

    Language English
    Publishing date 2023-06-02
    Publishing country England
    Document type Journal Article ; Comment
    ISSN 2058-5276
    ISSN (online) 2058-5276
    DOI 10.1038/s41564-023-01390-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Anti-ADAMTS13 Autoantibodies: From Pathophysiology to Prognostic Impact-A Review for Clinicians.

    Dainese, Cristina / Valeri, Federica / Bruno, Benedetto / Borchiellini, Alessandra

    Journal of clinical medicine

    2023  Volume 12, Issue 17

    Abstract: Thrombotic thrombocytopenic purpura (TTP) is a fatal disease in which platelet-rich microthrombi cause end-organ ischemia and damage. TTP is caused by markedly reduced ADAMTS13 (a disintegrin and metalloproteinase with a thrombospondin type 1 motif, ... ...

    Abstract Thrombotic thrombocytopenic purpura (TTP) is a fatal disease in which platelet-rich microthrombi cause end-organ ischemia and damage. TTP is caused by markedly reduced ADAMTS13 (a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13) activity. ADAMTS13 autoantibodies (autoAbs) are the major cause of immune TTP (iTTP), determining ADAMTS13 deficiency. The pathophysiology of such autoAbs as well as their prognostic role are continuous objects of scientific studies in iTTP fields. This review aims to provide clinicians with the basic information and updates on autoAbs' structure and function, how they are typically detected in the laboratory and their prognostic implications. This information could be useful in clinical practice and contribute to future research implementations on this specific topic.
    Language English
    Publishing date 2023-08-29
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm12175630
    Database MEDical Literature Analysis and Retrieval System OnLINE

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