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  1. Article ; Online: Primary small cell neuroendocrine cancer of adrenal gland: a rare extrapulmonary small cell cancer.

    Abdullah, Hafez Mohammad Ammar / Hassan, Masroor / Khan, Uzma Ikhtiar / Ellithi, Moataz

    BMJ case reports

    2023  Volume 16, Issue 2

    Abstract: Small cell cancer is an aggressive neoplasm of neuroendocrine origin that is most commonly found in the lungs. However, up to 5% of cases can be extrapulmonary. These have been reported to be located in the gastrointestinal and genitourinary systems and ... ...

    Abstract Small cell cancer is an aggressive neoplasm of neuroendocrine origin that is most commonly found in the lungs. However, up to 5% of cases can be extrapulmonary. These have been reported to be located in the gastrointestinal and genitourinary systems and rarely in other locations. Only five prior cases of small cell cancer have been reported where the primary lesion is at the adrenal gland. Here we present the case of a female patient in her mid-50s who presented with right upper quadrant pain and was diagnosed with metastatic small cell carcinoma of the adrenal gland. The patient received palliative chemotherapy for her metastatic cancer and was ultimately admitted to hospice after progression of her disease. This case and the accompanying literature review highlight a rare manifestation of extrapulmonary small cell cancer.
    MeSH term(s) Humans ; Female ; Carcinoma, Small Cell/pathology ; Lung Neoplasms/pathology ; Adrenal Glands/pathology ; Carcinoma, Neuroendocrine/pathology
    Language English
    Publishing date 2023-02-15
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2022-250828
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: A very unusual cause of severe right upper quadrant pain: splenic infarct in a patient with heterotaxy syndrome.

    Abdullah, Hafez Mohammad Ammar / Ahmed, Mamoon / Khan, Salman / Khan, Uzma Ikhtiar

    BMJ case reports

    2021  Volume 14, Issue 11

    MeSH term(s) Abdominal Pain/etiology ; Diagnosis, Differential ; Heterotaxy Syndrome/complications ; Heterotaxy Syndrome/diagnostic imaging ; Humans ; Splenic Infarction/diagnostic imaging ; Splenic Infarction/etiology
    Language English
    Publishing date 2021-11-11
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2021-246541
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Republished: Amiodarone-induced diffuse alveolar haemorrhage: a rare but potentially life-threatening complication of a commonly prescribed medication.

    Saeed, Jamaluddin / Waqas, Qazi Ahmed / Khan, Uzma Ikhtiar / Abdullah, Hafez Mohammad Ammar

    Drug and therapeutics bulletin

    2020  Volume 58, Issue 7, Page(s) 107–111

    Language English
    Publishing date 2020-04-30
    Publishing country England
    Document type Journal Article ; Corrected and Republished Article
    ZDB-ID 80242-6
    ISSN 1755-5248 ; 0012-6543
    ISSN (online) 1755-5248
    ISSN 0012-6543
    DOI 10.1136/dtb.2019.232149rep
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: High output heart failure in a young woman secondary to massive arteriovenous malformations from a uterine tumor.

    Abdullah, Hafez Mohammad Ammar / Oliver, Tony / Lamfers, Randall / Narayana Gowda, Smitha

    BMJ case reports

    2020  Volume 13, Issue 2

    MeSH term(s) Adult ; Arteriovenous Malformations/complications ; Arteriovenous Malformations/diagnostic imaging ; Arteriovenous Malformations/surgery ; Cardiac Output, High/etiology ; Embolization, Therapeutic ; Female ; Gestational Trophoblastic Disease/diagnosis ; Gestational Trophoblastic Disease/pathology ; Gestational Trophoblastic Disease/therapy ; Heart Failure/etiology ; Humans ; Hysterectomy ; Pregnancy ; Uterine Artery/abnormalities
    Language English
    Publishing date 2020-02-10
    Publishing country England
    Document type Case Reports
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2019-233887
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Percutaneous removal of a retained appendicolith causing recurrent perihepatic abscesses between the liver and diaphragm.

    Abdullah, Hafez Mohammad Ammar / Atiq, Muslim / Yeager, Terry

    BMJ case reports

    2019  Volume 12, Issue 7

    Abstract: Many cases of appendicitis can be associated with appendicoliths. These may sometimes be lost during appendectomies and may be lodged in the body. Most of these cases lead to recurrent abscess formation, and these appendicoliths invariably need removal. ... ...

    Abstract Many cases of appendicitis can be associated with appendicoliths. These may sometimes be lost during appendectomies and may be lodged in the body. Most of these cases lead to recurrent abscess formation, and these appendicoliths invariably need removal. Typically, this used to be done as an open surgery or laparoscopically. Here we describe the case of a transcutaneous removal of an appendicolith that was lodged between the liver and diaphragm that led to recurrent perihepatic abscess formation in a 24-year-old otherwise healthy man. The patient made a successful recovery without any recurrence. A transcutaneous approach to remove a retained appendicolith may be a feasible, a safe and an easy method to extract appendicoliths that are accessible for transcutaneous removal.
    MeSH term(s) Abdominal Abscess/diagnostic imaging ; Abdominal Abscess/etiology ; Abdominal Abscess/surgery ; Appendectomy ; Appendicitis/surgery ; Calculi/complications ; Calculi/surgery ; Diaphragm/diagnostic imaging ; Foreign Bodies/complications ; Foreign Bodies/diagnostic imaging ; Foreign Bodies/surgery ; Humans ; Liver/diagnostic imaging ; Male ; Postoperative Complications/diagnostic imaging ; Postoperative Complications/surgery ; Recurrence ; Tomography, X-Ray Computed ; Young Adult
    Language English
    Publishing date 2019-07-18
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2019-230176
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Cardiac arrest in a young healthy male patient secondary to kratom ingestion: is this 'legal high' substance more dangerous than initially thought ?

    Abdullah, Hafez Mohammad Ammar / Haq, Iqra / Lamfers, Randall

    BMJ case reports

    2019  Volume 12, Issue 7

    Abstract: Kratom is a psychoactive herb that has stimulant properties at low doses and has opioid-like properties at higher doses. It has been used for centuries in southeast Asia as a stimulant but has gained increasing popularity as a substitute for opioids in ... ...

    Abstract Kratom is a psychoactive herb that has stimulant properties at low doses and has opioid-like properties at higher doses. It has been used for centuries in southeast Asia as a stimulant but has gained increasing popularity as a substitute for opioids in western countries as it is easily available. As most cases of kratom use involve other drugs too, the Food and Drug Administration (FDA) has stopped short of restricting kratom due to difficulty in assessing the adverse effects of kratom alone. We present the case of a young healthy 35-year-old man who suffered a cardiac arrest due to kratom use with no other coingestants. He was subsequently intubated and found to have systolic dysfunction and small brain infarcts. Fortunately, he made a successful recovery and was discharged after a stay at thebehavioural health centre. Our case highlights the potential adverse effects of kratom and the need to regulate its use.
    MeSH term(s) Adult ; Brain Infarction/chemically induced ; Brain Infarction/therapy ; Diagnosis, Differential ; Heart Arrest/chemically induced ; Heart Arrest/therapy ; Humans ; Hypothermia, Induced ; Male ; Mitragyna/poisoning ; Psychotropic Drugs/adverse effects ; Substance Withdrawal Syndrome
    Chemical Substances Psychotropic Drugs
    Language English
    Publishing date 2019-07-19
    Publishing country England
    Document type Journal Article ; Case Reports
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2019-229778
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: A not so happy ending: coital cephalgia resulting from an acute non-traumatic intraparenchymal haemorrhage in a female with no comorbidities.

    Abdullah, Hafez Mohammad Ammar / Khan, Uzma Ikhtiar / Tariq, Ezza / Omar, Muhammad

    BMJ case reports

    2019  Volume 12, Issue 5

    Abstract: A sexual headache or coital cephalgia is a headache associated with sexual activity and is a well-recognised condition. It is usually benign, primary and self-limiting. However, occasionally sexual headaches can result from more sinister causes. ... ...

    Abstract A sexual headache or coital cephalgia is a headache associated with sexual activity and is a well-recognised condition. It is usually benign, primary and self-limiting. However, occasionally sexual headaches can result from more sinister causes. Intraparenchymal and subdural haemorrhages have been reported as secondary causes of sexual headaches. We present the case of a 61-year-old woman with no comorbidities who presented acutely with a sexual headache and vision loss, and was found to have an occipital and parietal intraparenchymal haemorrhage. She was normotensive and after extensive workup was found to have no predisposing condition for her haemorrhage. The patient had an uneventful recovery with physical rehabilitation and had regular follow-ups, with no residual weakness. She was in a completely normal state of health 1 year after her event, and continued to be off any medications.
    MeSH term(s) Acute Disease ; Coitus/physiology ; Female ; Headache/diagnosis ; Headache/etiology ; Headache/physiopathology ; Humans ; Intracranial Hemorrhages/complications ; Intracranial Hemorrhages/diagnosis ; Intracranial Hemorrhages/rehabilitation ; Middle Aged ; Sexual Behavior/physiology ; Treatment Outcome
    Language English
    Publishing date 2019-05-27
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2018-228872
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Human cytomegalovirus pneumonia in an immunocompetent patient: a very uncommon but treatable condition.

    Waqas, Qazi Ahmed / Abdullah, Hafez Mohammad Ammar / Khan, Uzma Ikhtiar / Oliver, Tony

    BMJ case reports

    2019  Volume 12, Issue 8

    Abstract: Human cytomegalovirus (CMV) is a double-stranded DNA virus that can cause widespread severe infection in immunocompromised individuals but is more typically a subclinical infection in immunocompetent individuals. Rarely, it can cause a serious infection ... ...

    Abstract Human cytomegalovirus (CMV) is a double-stranded DNA virus that can cause widespread severe infection in immunocompromised individuals but is more typically a subclinical infection in immunocompetent individuals. Rarely, it can cause a serious infection in immunocompetent individuals. Here, we describe a 36-year-old otherwise healthy male who presented with fever, cough and malaise who was diagnosed with CMV pneumonia. He made a rapid recovery after initiation of ganciclovir and has been doing well on follow-up visits. We performed a comprehensive review of CMV pneumonia in immunocompetent individuals and have summarised the prior 16 reported cases of CMV pneumonia in immunocompetent patients. This article highlights the importance of considering CMV as a cause of pneumonia even in immunocompetent individuals, especially when the more common causes have been excluded. Early diagnosis allows prompt treatment and potentially complete recovery.
    MeSH term(s) Adult ; Antiviral Agents/administration & dosage ; Cytomegalovirus/isolation & purification ; Cytomegalovirus Infections/diagnosis ; Cytomegalovirus Infections/drug therapy ; Cytomegalovirus Infections/immunology ; Cytomegalovirus Infections/physiopathology ; Early Diagnosis ; Early Medical Intervention/methods ; Ganciclovir/administration & dosage ; Humans ; Immunocompetence ; Male ; Pneumonia/diagnosis ; Pneumonia/drug therapy ; Pneumonia/physiopathology ; Pneumonia/virology ; Treatment Outcome
    Chemical Substances Antiviral Agents ; Ganciclovir (P9G3CKZ4P5)
    Language English
    Publishing date 2019-08-26
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2019-230229
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Amiodarone-induced diffuse alveolar haemorrhage: a rare but potentially life-threatening complication of a commonly prescribed medication.

    Saeed, Jamaluddin / Waqas, Qazi Ahmed / Khan, Uzma Ikhtiar / Abdullah, Hafez Mohammad Ammar

    BMJ case reports

    2019  Volume 12, Issue 10

    Abstract: Amiodarone is an antiarrhythmic agent that is used commonly in clinical practice. It is associated with many side effects, the most common being pulmonary manifestations. Interstitial pneumonitis is one of the most common complications, however rarely ... ...

    Abstract Amiodarone is an antiarrhythmic agent that is used commonly in clinical practice. It is associated with many side effects, the most common being pulmonary manifestations. Interstitial pneumonitis is one of the most common complications, however rarely amiodarone can cause diffuse alveolar haemorrhage (DAH) too. We describe the case of a 73-year-old woman who presented with shortness of breath and haemoptysis 4 days after starting amiodarone. She was diagnosed with amiodarone-induced DAH based on imaging and bronchoalveolar lavage. She was treated with intravenous and then oral steroids, and amiodarone was discontinued. The patient made a significant clinical and radiological recovery. She was discharged 10 days after her presentation. This case highlights a rare but potentially life-threatening complication of a commonly used medication.
    MeSH term(s) Aged ; Amiodarone/adverse effects ; Anti-Arrhythmia Agents/adverse effects ; Diagnosis, Differential ; Female ; Hemorrhage/chemically induced ; Hemorrhage/diagnostic imaging ; Hemorrhage/drug therapy ; Humans ; Lung Diseases, Interstitial/chemically induced ; Lung Diseases, Interstitial/diagnostic imaging ; Lung Diseases, Interstitial/drug therapy ; Radiography ; Steroids/therapeutic use
    Chemical Substances Anti-Arrhythmia Agents ; Steroids ; Amiodarone (N3RQ532IUT)
    Language English
    Publishing date 2019-10-25
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2019-232149
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Cardiac tamponade and purulent pericarditis secondary to an oesophageal pericardial fistula as an initial presentation of squamous cell carcinoma of the oesophagus.

    Abdullah, Hafez Mohammad Ammar / Khan, Uzma Ikhtiar / Wasekar, Chetan / Omar, Muhammad

    BMJ case reports

    2019  Volume 12, Issue 7

    Abstract: Pericardial effusions resulting in a cardiac tamponade have previously been reported with oesophageal cancers. However, most of these cases have been reported in association with radiation and chemotherapy. Rarely as oesophageal pericardial fistuls (OPF) ...

    Abstract Pericardial effusions resulting in a cardiac tamponade have previously been reported with oesophageal cancers. However, most of these cases have been reported in association with radiation and chemotherapy. Rarely as oesophageal pericardial fistuls (OPF) have been reported as the culprits in causing pericardial effusions in patients with oesophageal cancers. Here we present the case of a 61-year-old woman who presented clinically with cardiac tamponade. She was found to have an OPF due to oesophageal squamous cell cancer that resulted in a purulent pericardial effusion. She underwent a median sternotomy, pericardial decompression, and mediastinal debridement. An oesophageal stent was attempted unsuccessfully. The patient refused any more aggressive treatments and was discharged to a hospice where she passed away 13 days after presentation. This case and the associated literature review highlights an unusual presentation of oesophageal cancer and an uncommon cause of cardiac tamponade.
    MeSH term(s) Cardiac Tamponade/diagnosis ; Cardiac Tamponade/etiology ; Cardiac Tamponade/surgery ; Electrocardiography ; Endoscopy, Digestive System ; Esophageal Fistula/diagnosis ; Esophageal Fistula/etiology ; Esophageal Neoplasms/complications ; Esophageal Neoplasms/diagnosis ; Esophageal Neoplasms/pathology ; Esophageal Squamous Cell Carcinoma/complications ; Esophageal Squamous Cell Carcinoma/diagnosis ; Esophageal Squamous Cell Carcinoma/pathology ; Female ; Humans ; Mediastinitis/complications ; Middle Aged ; Pericarditis/diagnosis ; Pericarditis/etiology ; Pericarditis/surgery ; Suppuration ; Tomography, X-Ray Computed
    Language English
    Publishing date 2019-07-17
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2019-229634
    Database MEDical Literature Analysis and Retrieval System OnLINE

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