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  1. Article ; Online: Heart Failure Associated with Socioeconomic Status Stronger in Younger Patients: A French Nationwide Cohort Study.

    Domengé, Orianne / Lecoeur, Emmanuel / Chavarot, Nathalie / Hulot, Jean-Sébastien / Jannot, Anne-Sophie

    European journal of preventive cardiology

    2024  

    Language English
    Publishing date 2024-03-05
    Publishing country England
    Document type Journal Article
    ZDB-ID 2626011-6
    ISSN 2047-4881 ; 2047-4873
    ISSN (online) 2047-4881
    ISSN 2047-4873
    DOI 10.1093/eurjpc/zwae083
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  2. Article: COVID-19: A One-center Experience in Paris.

    Chavarot, Nathalie / Fournier, Catherine / Burger, Carole / Amrouche, Lucile / Legendre, Christophe

    Transplantation direct

    2020  Volume 7, Issue 1, Page(s) e647

    Language English
    Publishing date 2020-12-18
    Publishing country United States
    Document type Journal Article
    ISSN 2373-8731
    ISSN 2373-8731
    DOI 10.1097/TXD.0000000000001066
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  3. Article ; Online: Stiripentol and Lumasiran as a Rescue Therapy for Oxalate Nephropathy Recurrence After Kidney Transplantation in an Adult Patient With Primary Hyperoxaluria Type 1.

    Lombardi, Yannis / Isnard, Pierre / Chavarot, Nathalie / Chauvet, Sophie / Martinez, Frank / Thervet, Éric / Anglicheau, Dany / Karras, Alexandre

    American journal of kidney diseases : the official journal of the National Kidney Foundation

    2023  Volume 82, Issue 1, Page(s) 113–116

    Abstract: Primary hyperoxaluria type 1 is a rare cause of kidney failure. Stiripentol, an inhibitor of lactate dehydrogenase A, and lumasiran, a small interfering RNA targeting glycolate oxidase, have been proposed as therapeutic options, but clinical data are ... ...

    Abstract Primary hyperoxaluria type 1 is a rare cause of kidney failure. Stiripentol, an inhibitor of lactate dehydrogenase A, and lumasiran, a small interfering RNA targeting glycolate oxidase, have been proposed as therapeutic options, but clinical data are scarce, especially in adults and transplanted patients. We describe the case of a 51-year-old patient with a biopsy-proven recurrence of oxalate nephropathy after a kidney-only transplantation. He received stiripentol and lumasiran without adverse events. Fourteen months after transplantation, graft function, serum, and urinary oxalate levels have remained stable, and kidney biopsy showed a complete regression of oxalate crystals. Further studies are needed to assess whether this strategy is effective and could replace liver-kidney transplantation.
    MeSH term(s) Male ; Humans ; Adult ; Middle Aged ; Kidney Transplantation/adverse effects ; Hyperoxaluria, Primary/complications ; Hyperoxaluria, Primary/surgery ; Hyperoxaluria/etiology ; RNA, Small Interfering ; Renal Insufficiency/etiology ; Oxalates
    Chemical Substances stiripentol (R02XOT8V8I) ; lumasiran (RZT8C352O1) ; RNA, Small Interfering ; Oxalates
    Language English
    Publishing date 2023-01-21
    Publishing country United States
    Document type Case Reports
    ZDB-ID 604539-x
    ISSN 1523-6838 ; 0272-6386
    ISSN (online) 1523-6838
    ISSN 0272-6386
    DOI 10.1053/j.ajkd.2022.12.005
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    Zs.A 1669: Show issues Location:
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  4. Article ; Online: Vaccination anti-COVID-19 chez les patients dialysés et transplantés rénaux.

    Sakhi, Hamza / Chavarot, Nathalie / Attias, Philippe / El Karoui, Khalil / Anglicheau, Dany

    Nephrologie & therapeutique

    2021  Volume 17, Issue 4, Page(s) 208–213

    Abstract: Patients with end stage renal disease, including dialysis and kidney transplantation, have a high risk of severe COVID-19. In these populations, post-COVID-19 humoral response is prolonged until 6 months post-infection. However, post-vaccination humoral ... ...

    Title translation COVID-19 vaccination in dialysis and kidney transplant patients.
    Abstract Patients with end stage renal disease, including dialysis and kidney transplantation, have a high risk of severe COVID-19. In these populations, post-COVID-19 humoral response is prolonged until 6 months post-infection. However, post-vaccination humoral responses are frequently weak even when positive, notably in kidney transplant patients treated with belatacept. Actually, after 2 injectionos of mRNA vaccines, humoral response rates are 80-95% in dialysis patients, 30-50% in transplant patients, and about 5% in transplant patients treated with belatacept. These results have led to propose a 3rd injection of mRNA vaccine in dialysis and transplant patients in France. Numerous questions, regarding cellular responses, durability of response and clinical efficacy of vaccines remain in these high risk populations.
    MeSH term(s) COVID-19 Vaccines ; Humans ; Kidney Transplantation ; Renal Dialysis ; Transplant Recipients
    Chemical Substances COVID-19 Vaccines
    Language French
    Publishing date 2021-07-01
    Publishing country France
    Document type Journal Article
    ZDB-ID 2229575-6
    ISSN 1872-9177 ; 1769-7255
    ISSN (online) 1872-9177
    ISSN 1769-7255
    DOI 10.1016/j.nephro.2021.06.005
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  5. Article ; Online: Immunogenicity of Anti-SARS-CoV-2 Vaccination After Kidney Transplantation in Kidney Transplant Recipients Vaccinated Before Transplantation.

    Uro-Coste, Charlotte / Sberro-Soussan, Rebecca / Martinez, Frank / Amrouche, Lucile / Aubert, Olivier / Leruez-Ville, Marianne / Delage, Claire / Peraldi, Marie Noëlle / Legendre, Christophe / Lanternier, Fanny / Zuber, Julien / Anglicheau, Dany / Scemla, Anne / Chavarot, Nathalie

    Transplantation

    2023  Volume 107, Issue 8, Page(s) e213–e214

    MeSH term(s) Humans ; Kidney Transplantation/adverse effects ; COVID-19/prevention & control ; Transplant Recipients ; Vaccination ; Antibodies, Viral
    Chemical Substances Antibodies, Viral
    Language English
    Publishing date 2023-05-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 208424-7
    ISSN 1534-6080 ; 0041-1337
    ISSN (online) 1534-6080
    ISSN 0041-1337
    DOI 10.1097/TP.0000000000004654
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    Zs.A 488: Show issues Location:
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    Zs.MO 509: Show issues

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  6. Article ; Online: Biphosphonate Therapy, Risk of Fracture, and Sites of Bone Mineral Density Assessments in Kidney Transplantation.

    Tabibzadeh, Nahid / Chavarot, Nathalie / Flamant, Martin / Vidal-Petiot, Emmanuelle

    Journal of the American Society of Nephrology : JASN

    2019  Volume 30, Issue 5, Page(s) 905

    MeSH term(s) Bone Density ; Chronic Kidney Disease-Mineral and Bone Disorder ; Fractures, Bone ; Humans ; Kidney Transplantation ; Zoledronic Acid
    Chemical Substances Zoledronic Acid (6XC1PAD3KF)
    Language English
    Publishing date 2019-03-25
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 1085942-1
    ISSN 1533-3450 ; 1046-6673
    ISSN (online) 1533-3450
    ISSN 1046-6673
    DOI 10.1681/ASN.2019010079
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    Zs.A 3344: Show issues Location:
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  7. Article: Increased Risk of Invasive Aspergillosis in Immunocompromised Patients With Persistent SARS-CoV-2 Viral Shedding >8 Weeks, Retrospective Case-control Study.

    Melenotte, Cléa / Chavarot, Nathalie / L'Honneur, Anne-Sophie / Bodard, Sylvain / Cheminant, Morgane / Flahault, Adrien / Nguyen, Yann / Burgard, Marianne / Dannaoui, Eric / Bougnoux, Marie-Elisabeth / Parize, Perrine / Rouzaud, Claire / Scemla, Anne / Canouï, Etienne / Lafont, Emmanuel / Vimpere, Damien / Zuber, Julien / Charlier, Caroline / Suarez, Felipe /
    Anglicheau, Dany / Hermine, Olivier / Lanternier, Fanny / Mouthon, Luc / Lortholary, Olivier

    Open forum infectious diseases

    2024  Volume 11, Issue 2, Page(s) ofae012

    Abstract: Background: Immunocompromised patients now represent the population most at risk for severe coronavirus disease 2019. Persistent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral shedding was reported in these patients ranging from ... ...

    Abstract Background: Immunocompromised patients now represent the population most at risk for severe coronavirus disease 2019. Persistent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral shedding was reported in these patients ranging from several weeks up to 9 months. We conducted a bicentric retrospective case-control study to identify risk and prognostic factors associated with persistent viral shedding in immunocompromised patients.
    Material and methods: Symptomatic immunocompromised adults with persistent SARS-CoV-2 viral shedding >8 weeks were retrospectively included between 1 March 2020 and 24 April 2022 at 2 university hospitals in Paris, France, and matched with a control group consisting of symptomatic immunocompromised patients without persistent viral shedding.
    Results: Twenty-nine immunocompromised patients with persistent viral shedding were compared with 40 controls. In multivariate analysis, fever and lymphocytopenia (<0.5 G/L) were associated with an increased risk of persistent viral shedding (odds ratio [OR]: 3.3; 95% confidence interval [CI], 1.01-11.09)
    Conclusions: Vaccine coverage was protective against SARS-CoV-2 persistent viral shedding in immunocompromised patients. This new group of immunocompromised patients with SARS-CoV-2 persistent viral shedding is at risk of developing invasive aspergillosis and death and should therefore be systematically screened for this fungal infection for as long as the viral shedding persists.
    Language English
    Publishing date 2024-01-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2757767-3
    ISSN 2328-8957
    ISSN 2328-8957
    DOI 10.1093/ofid/ofae012
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  8. Article ; Online: Bortezomib Does Not Prevent the Occurrence of Kaposi's Sarcoma in Patients with Haematological Malignancies: Two Case Reports.

    Chavarot, Nathalie / Lebbe, Celeste / Thervet, Eric / Bouscary, Didier / Karras, Alexandre

    Acta dermato-venereologica

    2017  Volume 97, Issue 9, Page(s) 1138–1139

    Abstract: is missing (Short communication). ...

    Abstract is missing (Short communication).
    Language English
    Publishing date 2017-10-02
    Publishing country Sweden
    Document type Journal Article
    ZDB-ID 80007-7
    ISSN 1651-2057 ; 0001-5555
    ISSN (online) 1651-2057
    ISSN 0001-5555
    DOI 10.2340/00015555-2727
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  9. Article ; Online: De novo posttransplant membranous nephropathy following BNT162b2 mRNA COVID-19 vaccine in a kidney transplant recipient.

    Chavarot, Nathalie / Padden, Michael / Amrouche, Lucile / Malard, Stéphanie / Scemla, Anne / Sberro-Soussan, Rebecca / Léon, Juliette / Legendre, Christophe / Duong, Jean Paul / Zuber, Julien / Anglicheau, Dany / Rabant, Marion / Isnard, Pierre

    American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

    2022  Volume 22, Issue 12, Page(s) 3188–3189

    MeSH term(s) Humans ; BNT162 Vaccine ; COVID-19/epidemiology ; COVID-19/prevention & control ; COVID-19 Vaccines/adverse effects ; Glomerulonephritis, Membranous/etiology ; Kidney Transplantation/adverse effects ; RNA, Messenger
    Chemical Substances BNT162 Vaccine ; COVID-19 Vaccines ; RNA, Messenger
    Language English
    Publishing date 2022-08-24
    Publishing country United States
    Document type Letter
    ZDB-ID 2060594-8
    ISSN 1600-6143 ; 1600-6135
    ISSN (online) 1600-6143
    ISSN 1600-6135
    DOI 10.1111/ajt.17166
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  10. Article ; Online: CMV-related anterior and intermediate uveitis in a kidney transplant recipient treated with belatacept.

    Morel, Antoine / Debieb, Amina Chahrazed / Mrejen, David / Amrouche, Lucile / Scemla, Anne / Vilain, Estelle / Legendre, Christophe / Anglicheau, Dany / Zuber, Julien / Brézin, Antoine / Chavarot, Nathalie

    European journal of ophthalmology

    2022  Volume 33, Issue 5, Page(s) NP47–NP50

    Abstract: Introduction: Belatacept is associated with a higher incidence of cytomegalovirus (CMV) disease and atypical presentations. Ocular manifestations are rare, representing up to 5% of disease manifestations and previous cases consisted in isolated ... ...

    Abstract Introduction: Belatacept is associated with a higher incidence of cytomegalovirus (CMV) disease and atypical presentations. Ocular manifestations are rare, representing up to 5% of disease manifestations and previous cases consisted in isolated retinitis.
    Case description: Herein, we report the case of an 81-year-old kidney transplant recipient who developed an anterior and intermediate uveitis under belatacept therapy. The diagnosis was established using quantitative CMV polymerase chain reaction assays in the aqueous humor. Belatacept was interrupted and oral and topical valganciclovir treatments were instituted. Lesions however extended, leading to intensify the treatment by intra-venous and intra-vitreal ganciclovir injections. Visual acuity stabilized and ocular inflammation was finally controlled after 3 months.
    Conclusion: Clinicians should be aware of CMV infection as a cause of anterior uveitis under belatacept-based regimen, even in the absence of symptoms suggestive of systemic CMV replication.
    MeSH term(s) Humans ; Aged, 80 and over ; Antiviral Agents/therapeutic use ; Abatacept/therapeutic use ; Kidney Transplantation/adverse effects ; Ganciclovir/therapeutic use ; Cytomegalovirus Infections/diagnosis ; Cytomegalovirus Infections/drug therapy ; Uveitis, Anterior/diagnosis ; Uveitis, Anterior/drug therapy ; Uveitis, Intermediate/drug therapy
    Chemical Substances Antiviral Agents ; Abatacept (7D0YB67S97) ; Ganciclovir (P9G3CKZ4P5)
    Language English
    Publishing date 2022-09-13
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 1089461-5
    ISSN 1724-6016 ; 1120-6721
    ISSN (online) 1724-6016
    ISSN 1120-6721
    DOI 10.1177/11206721221126308
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