LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 157

Search options

  1. Article ; Online: Bone Metastasis Challenge: New Ideas and Future.

    Scimeca, Manuel

    International journal of molecular sciences

    2023  Volume 24, Issue 7

    Abstract: Bone metastasis is a complex and challenging clinical problem, affecting patients with advanced stages of cancer [ ... ]. ...

    Abstract Bone metastasis is a complex and challenging clinical problem, affecting patients with advanced stages of cancer [...].
    MeSH term(s) Humans ; Bone Neoplasms/secondary
    Language English
    Publishing date 2023-03-24
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms24076161
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Article ; Online: Bone Metastasis Challenge

    Manuel Scimeca

    International Journal of Molecular Sciences, Vol 24, Iss 6161, p

    New Ideas and Future

    2023  Volume 6161

    Abstract: Bone metastasis is a complex and challenging clinical problem, affecting patients with advanced stages of cancer [.] ...

    Abstract Bone metastasis is a complex and challenging clinical problem, affecting patients with advanced stages of cancer [.]
    Keywords n/a ; Biology (General) ; QH301-705.5 ; Chemistry ; QD1-999
    Language English
    Publishing date 2023-03-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  3. Article ; Online: The impact of aluminum exposure on human health.

    Bonfiglio, Rita / Scimeca, Manuel / Mauriello, Alessandro

    Archives of toxicology

    2023  Volume 97, Issue 11, Page(s) 2997–2998

    MeSH term(s) Humans ; Aluminum/toxicity
    Chemical Substances Aluminum (CPD4NFA903)
    Language English
    Publishing date 2023-08-19
    Publishing country Germany
    Document type Editorial
    ZDB-ID 124992-7
    ISSN 1432-0738 ; 0340-5761
    ISSN (online) 1432-0738
    ISSN 0340-5761
    DOI 10.1007/s00204-023-03581-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Uf I Zs.90: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article ; Online: The impact of environmental pollution on cancer: Risk mitigation strategies to consider.

    Bonfiglio, Rita / Scimeca, Manuel / Mauriello, Alessandro

    The Science of the total environment

    2023  Volume 902, Page(s) 166219

    MeSH term(s) Humans ; Environmental Pollution ; Sustainable Development ; Neoplasms/chemically induced ; Neoplasms/epidemiology ; United Nations ; Goals
    Language English
    Publishing date 2023-08-09
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 121506-1
    ISSN 1879-1026 ; 0048-9697
    ISSN (online) 1879-1026
    ISSN 0048-9697
    DOI 10.1016/j.scitotenv.2023.166219
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 949: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Article ; Online: Addressing environmental pollution and cancer: the imperative of the 2030 agenda.

    Bonfiglio, Rita / Scimeca, Manuel / Mauriello, Alessandro

    Future oncology (London, England)

    2023  Volume 19, Issue 34, Page(s) 2273–2276

    MeSH term(s) Humans ; Environmental Pollution/adverse effects ; Neoplasms/epidemiology ; Neoplasms/etiology ; Environmental Exposure/adverse effects ; Asbestos
    Chemical Substances Asbestos (1332-21-4)
    Language English
    Publishing date 2023-11-03
    Publishing country England
    Document type Editorial
    ZDB-ID 2274956-1
    ISSN 1744-8301 ; 1479-6694
    ISSN (online) 1744-8301
    ISSN 1479-6694
    DOI 10.2217/fon-2023-0617
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 6478: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  6. Article ; Online: Deer antlers: the fastest growing tissue with least cancer occurrence.

    Li, Chunyi / Li, Yan / Wang, Wenying / Scimeca, Manuel / Melino, Gerry / Du, Rui / Shi, Yufang

    Cell death and differentiation

    2023  Volume 30, Issue 12, Page(s) 2452–2461

    Abstract: Deer antlers are a bony organ solely able to acquired distinct unique attributes during evolution and all these attributes are against thus far known natural rules. One of them is as the fastest animal growing tissue (2 cm/day), they are remarkably ... ...

    Abstract Deer antlers are a bony organ solely able to acquired distinct unique attributes during evolution and all these attributes are against thus far known natural rules. One of them is as the fastest animal growing tissue (2 cm/day), they are remarkably cancer-free, despite high cell division rate. Although tumor-like nodules on the long-lived castrate antlers in some deer species do occur, but they are truly benign in nature. In this review, we tried to find the answer to this seemingly contradictory phenomenon based on the currently available information and give insights into possible clinic application. The antler growth center is located in its tip; the most intensive dividing cells are resident in the inner layer of reserve mesenchyme (RM), and these cells are more adopted to osteosarcoma rather than to normal bone tissues in gene expression profiles but acquire their energy mainly through aerobic oxidative phosphorylation pathway. To counteract propensity of neoplastic transformation, antlers evolved highly efficient apoptosis exactly in the RM, unparalleled by any known tissues; and annual wholesale cast to jettison the corps. Besides, some strong cancer suppressive genes including p53 cofactor genes and p53 regulator genes are highly positively selected by deer, which would have certainly contributed to curb tumorigenesis. Thus far, antler extracts and RM cells/exosomes have been tried on different cancer models either in vitro or in vivo, and all achieved positive results. These positive experimental results together with the anecdotal folklore that regular consumption of velvet antler is living with cancer-free would encourage us to test antlers in clinic settings.
    MeSH term(s) Animals ; Deer/genetics ; Antlers/metabolism ; Tumor Suppressor Protein p53/genetics ; Tumor Suppressor Protein p53/metabolism ; Bone and Bones ; Neoplasms/metabolism
    Chemical Substances Tumor Suppressor Protein p53
    Language English
    Publishing date 2023-10-20
    Publishing country England
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 1225672-9
    ISSN 1476-5403 ; 1350-9047
    ISSN (online) 1476-5403
    ISSN 1350-9047
    DOI 10.1038/s41418-023-01231-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 4230: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MG 80: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  7. Article ; Online: Preclinical Investigation of Radiopharmaceuticals: An Accurate and Multidisciplinary Approach.

    Urbano, Nicoletta / Scimeca, Manuel / Bonanno, Elena / Schillaci, Orazio

    Current radiopharmaceuticals

    2021  Volume 15, Issue 2, Page(s) 157–163

    Abstract: Background: The development of less expensive and pivotal methodologies capable of supporting the researchers in the radiopharmaceutical pre-clinical investigations could provide a crucial incentive for conducting biomedical research involved in the ... ...

    Abstract Background: The development of less expensive and pivotal methodologies capable of supporting the researchers in the radiopharmaceutical pre-clinical investigations could provide a crucial incentive for conducting biomedical research involved in the realization of tailored target therapies.
    Objective: The aim of this pilot study was to evaluate the capability of a digital autoradiography system equipped with a laser scanning device to perform [
    Methods: PC3 prostate cancer cells were used to develop NOD/SCID mice xenografts. The biodistribution of the radiopharmaceuticals was evaluated at 30, 60, and 120 min after injecting in excised organs by using a digital autoradiography system equipped with a super-resolution laser screen. Histological and immunohistochemical analyses were performed to correlate the [
    Results: The reported data clearly indicate the possibility of performing accurate biodistribution studies using the digital autoradiographic system equipped with a super-resolution screen. Specifically, a significant increase in the [
    Conclusion: The use of an autoradiography system in pre-clinical investigations could shed new light on the molecular mechanisms that orchestrate the tissues damage induced by therapeutical radiopharmaceuticals.
    MeSH term(s) Animals ; Cell Line, Tumor ; Choline/chemistry ; Fluorine Radioisotopes/pharmacology ; Humans ; Male ; Mice ; Mice, Inbred NOD ; Mice, SCID ; Pilot Projects ; Positron-Emission Tomography/methods ; Prostatic Neoplasms/diagnostic imaging ; Prostatic Neoplasms/metabolism ; Prostatic Neoplasms/radiotherapy ; Radiopharmaceuticals/chemistry ; Radiopharmaceuticals/pharmacology ; Tissue Distribution
    Chemical Substances Fluorine Radioisotopes ; Radiopharmaceuticals ; Choline (N91BDP6H0X)
    Language English
    Publishing date 2021-12-09
    Publishing country United Arab Emirates
    Document type Journal Article
    ISSN 1874-4729
    ISSN (online) 1874-4729
    DOI 10.2174/1874471014666211209154317
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  8. Article ; Online: Precision medicine in breast cancer: From biological imaging to artificial intelligence.

    Scimeca, Manuel / Urbano, Nicoletta / Toschi, Nicola / Bonanno, Elena / Schillaci, Orazio

    Seminars in cancer biology

    2021  Volume 72, Page(s) 1–3

    MeSH term(s) Artificial Intelligence ; Breast Neoplasms/diagnostic imaging ; Breast Neoplasms/pathology ; Female ; Humans ; Multimodal Imaging/methods ; Precision Medicine
    Language English
    Publishing date 2021-04-29
    Publishing country England
    Document type Editorial ; Introductory Journal Article
    ZDB-ID 1033980-2
    ISSN 1096-3650 ; 1044-579X
    ISSN (online) 1096-3650
    ISSN 1044-579X
    DOI 10.1016/j.semcancer.2021.04.019
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 2922: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  9. Article ; Online: Bone Morphogenetic Proteins, Satellite Cells, and Sarcopenia: Perspective in Translational Medicine.

    Tarantino, Umberto / Scimeca, Manuel

    The journals of gerontology. Series A, Biological sciences and medical sciences

    2018  Volume 73, Issue 12, Page(s) 1591–1593

    MeSH term(s) Aged ; Aging/physiology ; Animals ; Bone Morphogenetic Proteins/metabolism ; Geriatric Assessment/methods ; Humans ; Sarcopenia/metabolism ; Sarcopenia/pathology ; Satellite Cells, Skeletal Muscle/cytology ; Satellite Cells, Skeletal Muscle/metabolism ; Sensitivity and Specificity ; Translational Medical Research
    Chemical Substances Bone Morphogenetic Proteins
    Language English
    Publishing date 2018-04-16
    Publishing country United States
    Document type Editorial
    ZDB-ID 1223643-3
    ISSN 1758-535X ; 1079-5006
    ISSN (online) 1758-535X
    ISSN 1079-5006
    DOI 10.1093/gerona/gly079
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Uc I Zs.242/A: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  10. Article ; Online: Possible role of

    Urbano, Nicoletta / Scimeca, Manuel / Bonfiglio, Rita / Bonanno, Elena / Schillaci, Orazio

    Revista espanola de medicina nuclear e imagen molecular

    2021  Volume 41, Issue 3, Page(s) 201

    MeSH term(s) COVID-19/diagnostic imaging ; Follow-Up Studies ; Humans ; Radionuclide Imaging ; SARS-CoV-2 ; Technetium Tc 99m Sestamibi
    Chemical Substances Technetium Tc 99m Sestamibi (971Z4W1S09)
    Language English
    Publishing date 2021-03-10
    Publishing country Spain
    Document type Letter
    ISSN 2253-8089
    ISSN (online) 2253-8089
    DOI 10.1016/j.remnie.2021.03.009
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

To top