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  1. Book ; Online ; E-Book: Neurogeriatrie

    Maetzler, Walter / Dodel, Richard C. / Jacobs, Andreas H.

    ICF-basierte Diagnose und Behandlung

    2019  

    Author's details Walter Maetzler, Richard Dodel, Andreas H. Jacobs (Hrsg.)
    Keywords Neurology ; Geriatrics ; Family medicine
    Subject code 616.8
    Language German
    Size 1 Online-Ressource (XVII, 326 Seiten), Illustrationen
    Publisher Springer
    Publishing place Berlin
    Publishing country Germany
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT019936444
    ISBN 978-3-662-57358-7 ; 9783662573570 ; 3-662-57358-X ; 3662573571
    DOI 10.1007/978-3-662-57358-7
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: Verdacht auf Demenz: So gelingt die Früh- und Differenzialdiagnose.

    Jacobs, Andreas H

    MMW Fortschritte der Medizin

    2022  Volume 164, Issue 10, Page(s) 32–39

    Title translation Early and differential diagnosis of dementia.
    MeSH term(s) Alzheimer Disease ; Dementia/diagnosis ; Diagnosis, Differential ; Humans
    Language German
    Publishing date 2022-05-18
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 1478211-x
    ISSN 1613-3560 ; 1438-3276
    ISSN (online) 1613-3560
    ISSN 1438-3276
    DOI 10.1007/s15006-022-1027-4
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  3. Article: Arzneimittelversorgung im Alter.

    Jacobs, Andreas H

    Medizinische Monatsschrift fur Pharmazeuten

    2018  Volume 39, Issue 10, Page(s) 403

    Title translation In process.
    Language German
    Publishing date 2018-07-30
    Publishing country Germany
    Document type Editorial
    ZDB-ID 132805-0
    ISSN 0342-9601
    ISSN 0342-9601
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  4. Article: Parkinson-Syndrome.

    Jacobs, Andreas H

    Medizinische Monatsschrift fur Pharmazeuten

    2018  Volume 39, Issue 7, Page(s) 273

    Title translation In process.
    Language German
    Publishing date 2018-06-28
    Publishing country Germany
    Document type Editorial
    ZDB-ID 132805-0
    ISSN 0342-9601
    ISSN 0342-9601
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  5. Article: Alterspharmakotherapie. Auf dem Weg zur "weisen" Therapieentscheidung

    Jacobs, Andreas H.

    Arzneimitteltherapie

    2018  Volume 36, Issue 4, Page(s) 117

    Language German
    Document type Article
    ZDB-ID 380334-x
    ISSN 0723-6913
    Database Current Contents Medicine

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  6. Book ; Online ; Thesis: Targeting developmental signalling pathways in experimental gliomas by overexpression of NUMB

    Euskirchen, Philipp / Jacobs, Andreas / Goldbrunner, Roland

    2011  

    Institution Max-Planck-Institut für Neurologische Forschung
    Author's details vorgelegt von Philipp Euskirchen ; 1. Berichterstatter: Professor Dr. med. A. Jacobs, 2. Berichterstatter: Universitätsprofessor Dr. med. R. Goldbrunner ; aus dem Max-Planck-Institut für neurologische Forschung mit Klaus-Joachim-Zülch-Laboratorien der Max-Planck-Gesellschaft und der Medizinischen Fakultät der Universität zu Köln
    Subject code 610
    Language English
    Size 75 S. : graph. Darst.
    Publishing country Germany
    Document type Book ; Online ; Thesis
    Thesis / German Habilitation thesis Köln, Univ., Diss., 2011
    HBZ-ID HT016881438
    DOI 10.4126/38m-000000432
    Database Repository for Life Sciences

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  7. Book ; Thesis: Targeting developmental signalling pathways in experimental gliomas by overexpression of NUMB

    Euskirchen, Philipp / Jacobs, Andreas / Goldbrunner, Roland

    2011  

    Institution Max-Planck-Institut für Neurologische Forschung
    Author's details vorgelegt von Philipp Euskirchen ; 1. Berichterstatter: Professor Dr. med. A. Jacobs, 2. Berichterstatter: Universitätsprofessor Dr. med. R. Goldbrunner ; aus dem Max-Planck-Institut für neurologische Forschung mit Klaus-Joachim-Zülch-Laboratorien der Max-Planck-Gesellschaft und der Medizinischen Fakultät der Universität zu Köln
    Subject code 610
    Language English
    Size 75 S. : graph. Darst.
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Köln, Univ., Diss., 2011
    HBZ-ID HT016979911
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    2011 D 1164 order for loan Magazin

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  8. Article ; Online: Seltene Ursache für ein postrenales Nierenversagen.

    Metzen, Maike / Kowar, Michael / Solleder, Gerold / Wilhelm, Kai / Jacobs, Andreas H

    Deutsche medizinische Wochenschrift (1946)

    2022  Volume 147, Issue 7, Page(s) 403–406

    Abstract: History and clinical findings:  In the following case report, we describe a patient with acute renal failure due to an urinary congestion level II-III under BCG-(Bacillus Calmette-Guérin)-therapy because of bladder cancer. Cystoscopy revealed the ... ...

    Title translation BCG-therapy as a rare reason for postrenal failure.
    Abstract History and clinical findings:  In the following case report, we describe a patient with acute renal failure due to an urinary congestion level II-III under BCG-(Bacillus Calmette-Guérin)-therapy because of bladder cancer. Cystoscopy revealed the diagnosis of BCG-induced intramural narrowing of distal ureters bilaterally.
    Therapy and further development:  After receiving a double-J-catheter the renal function returned to normal.
    Conclusions:  Although postrenal failure is relatively rare (5 %), also seldom causes such as medication-induced (e. g. BCG) ureter stenosis has to be included into the differential diagnosis.
    MeSH term(s) Administration, Intravesical ; BCG Vaccine/adverse effects ; Cystoscopy ; Female ; Humans ; Male ; Urinary Bladder Neoplasms/complications ; Urinary Bladder Neoplasms/therapy
    Chemical Substances BCG Vaccine
    Language German
    Publishing date 2022-03-28
    Publishing country Germany
    Document type Case Reports ; Journal Article
    ZDB-ID 200446-x
    ISSN 1439-4413 ; 0012-0472
    ISSN (online) 1439-4413
    ISSN 0012-0472
    DOI 10.1055/a-1766-3235
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  9. Article ; Online: Polycythämia vera in der differenzialdiagnostischen Abklärung kognitiver Defizite.

    Kowar, Michael / Wilhelm, Kai / Jacobs, Andreas H

    Deutsche medizinische Wochenschrift (1946)

    2020  Volume 145, Issue 22, Page(s) 1625–1627

    Abstract: History: A 82-years old woman was admitted with a progressive cognitive decline for further investigations and treatment.: Findings and diagnosis: In the computed tomography of the brain findings of subcortical artherosclerotic encephalopathy (SAE) ... ...

    Title translation Polycythemia vera as a cause for progressive cognitive impairment.
    Abstract History: A 82-years old woman was admitted with a progressive cognitive decline for further investigations and treatment.
    Findings and diagnosis: In the computed tomography of the brain findings of subcortical artherosclerotic encephalopathy (SAE) were present. Laboratory findings revealed elevated hemoglobin-levels (19.9 g/dl). In further investigations we found a mutation in JAK-2 as diagnostic sign for polycythemia vera (Pv). After specific treatment of the Pv cognition improved significantly.
    Discussion: In this case report we were able to relate the progressive cognitive impairment in the context of newly diagnosed Pv in conjunction with pre-existing SAE. After Pv-directed therapy cognition improved. This case report underlines the importance of a good diagnostic work-up of patients with cognitive impairment to rule out secondary and possible treatable causes.
    MeSH term(s) Aged, 80 and over ; Cognitive Dysfunction/diagnosis ; Cognitive Dysfunction/etiology ; Female ; Humans ; Janus Kinase 2/genetics ; Mutation/genetics ; Polycythemia Vera/complications ; Polycythemia Vera/diagnosis ; Polycythemia Vera/genetics
    Chemical Substances JAK2 protein, human (EC 2.7.10.2) ; Janus Kinase 2 (EC 2.7.10.2)
    Language German
    Publishing date 2020-11-03
    Publishing country Germany
    Document type Case Reports ; Journal Article
    ZDB-ID 200446-x
    ISSN 1439-4413 ; 0012-0472
    ISSN (online) 1439-4413
    ISSN 0012-0472
    DOI 10.1055/a-1219-9564
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  10. Article ; Online: Falls at advanced age - The importance to search for benign paroxysmal positional vertigo (BPPV).

    Krieger, Jasmin / Frackowiak, Monika / Berger, Moritz / Heneka, Michael T / Jacobs, Andreas H

    Experimental gerontology

    2022  Volume 165, Page(s) 111868

    Abstract: Introduction: One of the most important geriatric syndromes is dizziness in conjunction with gait disorder and consequent falls. There are various differential diagnoses for dizziness, one of them is benign paroxysmal positional vertigo (BPPV).: ... ...

    Abstract Introduction: One of the most important geriatric syndromes is dizziness in conjunction with gait disorder and consequent falls. There are various differential diagnoses for dizziness, one of them is benign paroxysmal positional vertigo (BPPV).
    Objectives: A targeted diagnostic work-up and treatment of BPPV can prevent subsequent falls and a decline in the patients' quality of life, prolonged hospitalization with unnecessary examinations and medication.
    Design: Prospective examination of patients with a positive medical history of BPPV.
    Setting and participants: All patients treated within the Department of Geriatrics between 05/2015 and 03/2018 were included. A total of n = 5166 patients were screened (n = 2651 geriatrics; n = 2515 controls).
    Methods: All patients from other wards subjected to a neurological examination due to vertigo served as controls. Patients with typical hints in the medical history for a BPPV were subjected to the diagnostic Dix-Hallpike maneuver and, if positive, subsequent canalith repositioning maneuvers. The percentage of successful positional treatments was determined in both groups.
    Results: N = 254 patients (4.9 %) had indications in the medical history for a BPPV. For 71 of n = 254 patients (28 %; in total 1.4 %; mean age: 78.4 ± 12.3 years) the diagnosis of BPPV was proven by a positive Dix-Hallpike maneuver. N = 39 (54.9 %) patients belong to the geriatric group (mean age 82 years) and n = 32 (45.1 %) to the control group (mean age 73.9 years). The frequency of BPPV was similar in both groups (1.3-1.5 %). In 91.9 % of patients the BPPV was localized in the posterior semicircular canal. Up to 93 % were asymptomatic after one or repeated canalith repositioning maneuvers.
    Conclusions and implications: The BPPV should be considered as an important differential diagnosis for geriatric patients with dizziness and falls. After therapeutic repositioning maneuvers most of the patients are asymptomatic. Therefore, targeted screening and therapy ("theragnostic") of BPPV at an advanced age increases diagnostic accuracy and prevents unnecessary examinations, medications and future falls.
    MeSH term(s) Aged ; Aged, 80 and over ; Benign Paroxysmal Positional Vertigo/diagnosis ; Benign Paroxysmal Positional Vertigo/therapy ; Dizziness ; Humans ; Neurologic Examination ; Prospective Studies ; Quality of Life
    Language English
    Publishing date 2022-06-11
    Publishing country England
    Document type Journal Article
    ZDB-ID 390992-x
    ISSN 1873-6815 ; 0531-5565
    ISSN (online) 1873-6815
    ISSN 0531-5565
    DOI 10.1016/j.exger.2022.111868
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