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Article ; Online: Bilateral lentiform and caudate nucleus lesions in a child with COVID-19: A case report.

Akçay, Nihal / Bakırtaş Palabıyık, Figen / Şevketoğlu, Esra

2022

Abstract: Neurological complications are frequently mentioned in the published reports regarding the coronavirus disease 2019 (COVID-19). Especially encephalopathy draws attention as the leading symptom or complication of COVID-19 in some reports. This article ... ...

Abstract	Neurological complications are frequently mentioned in the published reports regarding the coronavirus disease 2019 (COVID-19). Especially encephalopathy draws attention as the leading symptom or complication of COVID-19 in some reports. This article discussed a 3-year-old patient with bilateral lentiform and caudate nuclei involvement on brain imaging, who presented with mental status changes and acute muscular weakness, possibly due to COVID-19. To the best of our knowledge, this case is the first one showing pathological signal enhancement and edema in bilateral lentiform and caudate nuclei associated with COVID-19.
Language	English
Publishing date	2022-06-06
Publishing country	United States
Document type	Journal Article
ZDB-ID	2698541-X
ISSN	2320-2890 ; 2320-2890
ISSN (online)	2320-2890
ISSN	2320-2890
DOI	10.1016/j.bj.2022.05.009
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Article ; Online: COVID-19-associated transverse myelitis treated by therapeutic plasma exchange: A case report.

Akçay, Nihal / Menentoğlu, Mehmet Emin / Oğur, Mustafa / Tosun, Demet / Palabıyık, Figen Bakırtaş / Şevketoğlu, Esra

Journal of clinical apheresis

2022 Volume 38, Issue 1, Page(s) 65–68

Abstract: Background: Transverse myelitis (TM) is a very uncommon condition in children which can be associated with viral infections. Acute TM cases have been reported after Coronavirus disease 2019 (COVID-19) infection during the pandemic.: Case report: We ... ...

Abstract	Background: Transverse myelitis (TM) is a very uncommon condition in children which can be associated with viral infections. Acute TM cases have been reported after Coronavirus disease 2019 (COVID-19) infection during the pandemic. Case report: We report a child with TM related to severe acute respiratory syndrome coronavirus 2, who was successfully treated with therapeutic plasma exchange (TPE). Inability to walk and urinary retention were the central nervous system symptom. Spinal magnetic resonance imaging revealed signal changes in the spinal cord. Her neurological symptoms worsened despite receiving IVIG and high-dose steroids for the first 3 d. We performed 10 TPE sessions with 5% albumin replacement and the neurological symptoms rapidly improved. Conclusion: We demonstrated that a child diagnosed with acute TM related to COVID-19 infection, was successfully treated with TPE.
MeSH term(s)	Child ; Female ; Humans ; Myelitis, Transverse/therapy ; Plasma Exchange ; COVID-19/complications ; COVID-19/therapy ; Plasmapheresis
Language	English
Publishing date	2022-10-13
Publishing country	United States
Document type	Case Reports
ZDB-ID	604912-6
ISSN	1098-1101 ; 0733-2459
ISSN (online)	1098-1101
ISSN	0733-2459
DOI	10.1002/jca.22024
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Zs.A 1831: Show issues

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Jg. 1995 - 2021: Lesesall (1.OG)
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Article: Volumetric apparent diffusion coefficient (ADC) histogram analysis of the brain in paediatric patients with hypoxic ischaemic encephalopathy.

Nalbant, Mustafa Orhan / Erdil, Irem / Akcay, Nihal / Inci, Ercan / Palabiyik, Figen

Polish journal of radiology

2023 Volume 88, Page(s) e399–e406

Abstract: Purpose: To evaluate the whole brain, hippocampus, thalamus, and lentiform nucleus by volumetric apparent diffusion coefficient (ADC) histogram analysis in paediatric patients with hypoxic-ischaemic encephalopathy (HIE).: Material and methods: This ... ...

Abstract	Purpose: To evaluate the whole brain, hippocampus, thalamus, and lentiform nucleus by volumetric apparent diffusion coefficient (ADC) histogram analysis in paediatric patients with hypoxic-ischaemic encephalopathy (HIE). Material and methods: This retrospective study included 25 patients with HIE and 50 patients as the control group. Diffusion-weighted imaging was obtained at Results: ADC Conclusions: Volumetric ADC histogram analysis of the whole brain, hippocampus, thalamus, and lentiform nucleus with
Language	English
Publishing date	2023-09-06
Publishing country	Poland
Document type	Journal Article
ZDB-ID	2675143-4
ISSN	1899-0967 ; 1733-134X
ISSN (online)	1899-0967
ISSN	1733-134X
DOI	10.5114/pjr.2023.131696
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Article ; Online: Evaluation of Cerebrovascular Events Followed in Pediatric Intensive Care Unit.

Barlas, Ulkem Kocoglu / Akcay, Nihal / Menentoglu, Mehmet Emin / Palabiyik, Figen Bakirtas / Sevketoglu, Esra

Turkish neurosurgery

2023 Volume 33, Issue 6, Page(s) 1058–1068

Abstract: Aim: To evaluate the effect of intensive care follow-up and treatment methods on the prognosis of 28 patients admitted to the pediatric intensive care unit (PICU) due to stroke.: Material and methods: The data of patients aged between 28 days and 18 ... ...

Abstract	Aim: To evaluate the effect of intensive care follow-up and treatment methods on the prognosis of 28 patients admitted to the pediatric intensive care unit (PICU) due to stroke. Material and methods: The data of patients aged between 28 days and 18 years followed up between 2011 and 2021 were recorded retrospectively. Results: Thirteen (48.1%) patients were diagnosed with hemorrhagic stroke (HS), 11 (40.7%) patients were diagnosed with acute ischemic stroke (AIS), and three (11.1%) patients were diagnosed with cerebral sinus vein thrombosis. One patient was followed up for non-ruptured arteriovenous malformation (AVM) and was excluded from the HS group. The HS group consisted of eight patients with ruptured AVMs and five patients with ruptured intracranial aneurysms. The patients had male predominance, and seizures and headache were the most common complaints on admission. The rate of admissions due to seizures was higher in the AIS group. In the HS group, there was more involvement of the right side of the brain. Middle cerebral artery (MCA) involvement was higher in the AIS group. The AIS group had longer PICU hospitalization days and mechanical ventilator days. While unfractionated heparin was preferred for the treatment in the AIS group, endovascular embolization was preferred in the HS group. Decompressive surgery was performed in five patients. The overall mortality rate was 7.1%. Conclusion: Although cerebrovascular events are rare in the pediatric population, achieving low mortality and morbidity is possible with the correct diagnostic and treatment methods.
MeSH term(s)	Humans ; Male ; Child ; Infant, Newborn ; Female ; Treatment Outcome ; Retrospective Studies ; Ischemic Stroke/therapy ; Heparin ; Intracranial Arteriovenous Malformations/surgery ; Embolization, Therapeutic/methods ; Aneurysm, Ruptured ; Seizures/epidemiology ; Seizures/etiology
Chemical Substances	Heparin (9005-49-6)
Language	English
Publishing date	2023-10-17
Publishing country	Turkey
Document type	Journal Article
ZDB-ID	1203779-5
ISSN	2651-5032 ; 1019-5149
ISSN (online)	2651-5032
ISSN	1019-5149
DOI	10.5137/1019-5149.JTN.43360-23.2
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Zs.A 4081: Show issues

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Article: Cerebrovascular Complications in Pediatric Patients with COVID-19 Infection

Chaudhry, Thymur Ali / Palabiyik, Figen / Moum, Sarah J.

Journal of Pediatric Neurology

(Pediatric Neuroradiology)

2022 Volume 20, Issue 05, Page(s) 310–318

Abstract: Since the onset of the coronavirus disease 2019 pandemic, a variety of neurological manifestations of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been reported in patients, of which one of the most concerning is stroke. This review ... ...

Series title	Pediatric Neuroradiology
Abstract	Since the onset of the coronavirus disease 2019 pandemic, a variety of neurological manifestations of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been reported in patients, of which one of the most concerning is stroke. This review aims to summarize the current literature and evolving understanding of pediatric cerebrovascular complications in the setting of SARS-CoV-2.
Keywords	pediatric stroke ; SARS-CoV-2 ; cerebrovascular complications
Language	English
Publishing date	2022-08-02
Publisher	Georg Thieme Verlag KG
Publishing place	Stuttgart ; New York
Document type	Article
ISSN	1875-9041 ; 1304-2580
ISSN (online)	1875-9041
ISSN	1304-2580
DOI	10.1055/s-0042-1751265
Database	Thieme publisher's database

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Article: Nonvascular Nervous System Complications in Pediatric Patients with COVID-19 Infection

Palabiyik, Figen / Koral, Korgün / Pruthi, Sumit

Journal of Pediatric Neurology

(Pediatric Neuroradiology)

2022 Volume 20, Issue 05, Page(s) 319–326

Abstract: Coronavirus disease (COVID-19) is caused by a novel severe acute respiratory syndrome coronavirus 2 virus which primarily targets the lungs. However, the central nervous system (CNS) and peripheral nervous system involvement due to COVID-19, however, has ...

Series title	Pediatric Neuroradiology
Abstract	Coronavirus disease (COVID-19) is caused by a novel severe acute respiratory syndrome coronavirus 2 virus which primarily targets the lungs. However, the central nervous system (CNS) and peripheral nervous system involvement due to COVID-19, however, has been reported as early as the cases of respiratory system involvement. In addition, there have been many reports describing neuroimaging features of COVID-19, but data beyond case studies in the pediatric population are still limited, indicating limited CNS involvement. The CNS involvement and complications include, but are not limited to, encephalopathy, meningoencephalitis, ischemic stroke, venous sinus thrombosis, acute necrotizing encephalopathy, acute disseminated encephalomyelitis, posterior reversible encephalopathy syndrome, acute cerebellitis, acute hemorrhagic myelitis, and Guillain–Barré syndrome. In this manuscript, we will discuss the imaging characteristics of some of these entities with a known diagnosis of COVID-19.
Keywords	COVID-19 ; central nervous system ; peripheral nervous system
Language	English
Publishing date	2022-08-24
Publisher	Georg Thieme Verlag KG
Publishing place	Stuttgart ; New York
Document type	Article
ISSN	1875-9041 ; 1304-2580
ISSN (online)	1875-9041
ISSN	1304-2580
DOI	10.1055/s-0042-1751264
Database	Thieme publisher's database

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Article: The performance of shear wave elastography on evaluating liver changes in obese and overweight children.

Sağlam, Neslihan Özkul / Aksoy, Sema / Kazancı, Selcen Yaroğlu / Palabıyık, Figen / Hatipoğlu, Sadık Sami / İnci, Ercan

The Turkish journal of pediatrics

2021 Volume 63, Issue 4, Page(s) 575–583

Abstract: Background: Real time shear-wave elastography (SWE) is a non-invasive imaging method which can quantitatively assess liver stiffness. Obesity and its complication are increasing with improving lifestyles in our century. We evaluated the performance of ... ...

Abstract	Background: Real time shear-wave elastography (SWE) is a non-invasive imaging method which can quantitatively assess liver stiffness. Obesity and its complication are increasing with improving lifestyles in our century. We evaluated the performance of SWE for detecting liver changes (fatty liver, steatohepatitis) in obese and overweight children, in addition to this, we determined the diagnostic accuracy and clinical usefulness of SWE in non-alcoholic fatty liver disease (NAFLD). Methods: Obese and overweight 41 children within the age range of 6-15 years were included in this singlecenter prospective study. Biochemical evaluation for aspartate aminotransferase (AST), alanine aminotransferase (ALT), triglyceride (TG), total cholesterol (TC) levels, as well as conventional ultrasound and SWE of the liver were performed in the patient group. These values were compared with values of 25 normal weight and healthy children in the age range of 6-16 years. Results: The mean SWE values was 13.7 ± 5.5 kiloPascal (kPa) and 2.03 ± 0.35 meter/second (m/s) in patient group and 7.99 ± 2.81 kPa and 1.62 ± 0.21 m/s in control group (p < 0.01). The receiver-operating characteristics (ROC) analysis was performed to determine the optimum cut-off value for elastography values (kPa) to evaluate liver changes; area under the curve was 87.5% (95% CI 79.3-95.8). When the cutoff value was set as 10.45 kPa, the sensitivity and the specificity was 69.2% and 100%, respectively. We could not observe a statistically significant difference when we compared the elastography values (kPa and m/s) according to presence of hepatosteatosis (p=0.581 and 0.172). There were no significant correlations between SWE and AST, ALT values. Conclusions: SWE may be a useful and accurate imaging method to evaluate liver changes and monitor NAFLD in obese and overweight children.
MeSH term(s)	Adolescent ; Child ; Elasticity Imaging Techniques ; Humans ; Liver/diagnostic imaging ; Liver/pathology ; Liver Cirrhosis/pathology ; Non-alcoholic Fatty Liver Disease/diagnostic imaging ; Obesity ; Prospective Studies
Language	English
Publishing date	2021-08-27
Publishing country	Turkey
Document type	Journal Article
ZDB-ID	123487-0
ISSN	0041-4301
ISSN	0041-4301
DOI	10.24953/turkjped.2021.04.004
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Zs.B 988: Show issues

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Article ; Online: Giant Pulmonary Abscess After COVID-19 Pneumonia

Nihal Akçay / Mehmet Emin Menentoğlu / Ayşe İrem Sofuoğlu / Mustafa Oğur / Figen Bakırtaş Palabıyık / Esra Şevketoğlu

Bagcilar Medical Bulletin, Vol 7, Iss 4, Pp 371-

A Case Report

2022 Volume 373

Abstract: The Coronavirus disease-2019 (COVID-19) in children is more likely to be asymptomatic or to have mild-to-moderate symptoms; however, severe cases have also been reported. A 10-year-old boy previously diagnosed with pontocerebellar hypoplasia presented ... ...

Abstract	The Coronavirus disease-2019 (COVID-19) in children is more likely to be asymptomatic or to have mild-to-moderate symptoms; however, severe cases have also been reported. A 10-year-old boy previously diagnosed with pontocerebellar hypoplasia presented with respiratory distress after 2 days of fever. He underwent tracheal intubation. He was COVID-19 positive. On day 10, a cystic area was observed in his chest radiography and thorax computer tomography also showed a thick-walled pulmonary abscess. Percutaneous empyema drainage was performed. On day 20, an open surgical tracheotomy was performed. On day 25, the percutaneous drainage catheter was removed. On day 55, he was discharged on the home ventilator and his chest radiography was normal. Children with COVID-19 may develop a pulmonary abscess secondary to superinfections during intensive care follow-up.
Keywords	child ; covid-19 ; pulmonary abscess ; superinfections ; Medicine ; R
Language	English
Publishing date	2022-12-01T00:00:00Z
Publisher	Galenos Yayinevi
Document type	Article ; Online
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Article ; Online: Temporal High-Resolution Computed Tomography and Magnetic Resonance Imaging of Congenital Inner Ear Anomalies in Children.

Palabiyik, Figen Bakirtas / Hacikurt, Kadir

The Journal of craniofacial surgery

2016 Volume 27, Issue 7, Page(s) e632–e636

Abstract: Imaging plays an important role in determining indications of cochlear implantation and choosing candidates for the procedure in children. Temporal high-resolution computed tomography (HRCT) and magnetic resonance imaging (MRI) can display precisely the ... ...

Abstract	Imaging plays an important role in determining indications of cochlear implantation and choosing candidates for the procedure in children. Temporal high-resolution computed tomography (HRCT) and magnetic resonance imaging (MRI) can display precisely the complex anatomic structure of inner ear. Although HRCT permits detailed imaging of bony structures, MRI gives valuable information about membranous labyrinth, internal acoustic canal, and vestibulocochlear nerve. Magnetic resonance imaging examination of the brain should be performed at the same time to evaluate any coexistent brain parenchymal abnormality. These imaging modalities are complementary methods in evaluating congenital inner ear anomalies. The aim of this pictorial essay is to reviewing temporal HRCT and MRI findings of congenital inner ear anomalies.
MeSH term(s)	Child ; Ear, Inner/abnormalities ; Ear, Inner/diagnostic imaging ; Humans ; Labyrinth Diseases/congenital ; Labyrinth Diseases/diagnosis ; Magnetic Resonance Imaging/methods ; Temporal Bone/diagnostic imaging ; Tomography, X-Ray Computed/methods
Language	English
Publishing date	2016-10
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	1159501-2
ISSN	1536-3732 ; 1049-2275
ISSN (online)	1536-3732
ISSN	1049-2275
DOI	10.1097/SCS.0000000000002981
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Zs.A 3761: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MO 175: Show issues

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Article ; Online: Imaging of Multisystem Inflammatory Disease in Children (MIS-C) Associated With COVID-19.

Palabiyik, Figen / Akcay, Nihal / Sevketoglu, Esra / Hatipoglu, Nevin / Sari, Emine Ergul / Inci, Ercan

Academic radiology

2021 Volume 28, Issue 9, Page(s) 1200–1208

Abstract: Rationale and objectives: To retrospectively evaluate imaging findings in multisystem inflammatory disease in children associated with COVID-19 (MIS-C).: Materials and methods: The radiological imaging findings of 45 pediatric patients aged between ... ...

Abstract	Rationale and objectives: To retrospectively evaluate imaging findings in multisystem inflammatory disease in children associated with COVID-19 (MIS-C). Materials and methods: The radiological imaging findings of 45 pediatric patients aged between 52 days and 16 years, who were diagnosed with MIS-C according to the World Health Organization (WHO) criteria, were evaluated. All the patients underwent chest X-ray and echocardiography. The findings obtained from 25 abdominal radiographs, 24 abdominal US, 7 abdominal CT, 16 thorax CT, 21 cranial MRI and one spinal MRI, MR cholangiography (MRCP) and cardiac MRI examinations were categorized and evaluated according to the affected systems. Results: While the most common findings in chest X-ray were perihilar opacity and peribronchial thickening, pleural effusion was the most finding in thorax CT. Echocardiography findings of myocarditis were observed in 31% of the cases. The most common findings in abdominal radiological evaluation were hepatomegaly and splenomegaly, edema in the gallbladder wall and periportal area, mesenteric lymph nodes in the right lower quadrant, thickening of the intestinal walls, and free fluid. Reversible splenial lesion syndrome (RESLES) was the most common neurological finding. Acute disseminated encephalomyelitis (ADEM)-like lesions, acute hemorrhagic necrotizing encephalomyelitis, and radiological findings consistent with Guillain-Barré syndrome were found in one case each. Conclusion: Radiological findings seen in MIS-C in pediatric cases are correlated with the affected system. According to the system involved, there is no specific finding for this disease. Radiological findings are not the primary diagnostic tool but can assist in the evaluation of the affected systems and to guide treatment.
MeSH term(s)	COVID-19 ; Child ; Echocardiography ; Humans ; Middle Aged ; Retrospective Studies ; SARS-CoV-2 ; Systemic Inflammatory Response Syndrome
Language	English
Publishing date	2021-06-05
Publishing country	United States
Document type	Journal Article
ZDB-ID	1355509-1
ISSN	1878-4046 ; 1076-6332
ISSN (online)	1878-4046
ISSN	1076-6332
DOI	10.1016/j.acra.2021.05.030
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