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  1. Article ; Online: Exploring filaggrin gene polymorphisms in Indian children with atopic dermatitis: Hitherto an unchartered territory.

    Bhatia, Riti / Gupta, Vishal

    Indian journal of dermatology, venereology and leprology

    2023  Volume 89, Issue 6, Page(s) 795–796

    MeSH term(s) Humans ; Child ; Dermatitis, Atopic ; Filaggrin Proteins ; Polymorphism, Genetic ; Genotype ; Intermediate Filament Proteins/genetics ; Intermediate Filament Proteins/metabolism ; Mutation
    Chemical Substances Filaggrin Proteins ; Intermediate Filament Proteins
    Language English
    Publishing date 2023-11-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 416068-x
    ISSN 0973-3922 ; 0019-5162 ; 0378-6323
    ISSN (online) 0973-3922
    ISSN 0019-5162 ; 0378-6323
    DOI 10.25259/IJDVL_1055_2023
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Rise up for Padma Shri Dr Maya Tandon as we salute the savior!

    Hemantkumar, Indrani / Malhotra, Naveen / Singla, Vishal / Bhatia, Pradeep / Chhabra, Swati

    Journal of anaesthesiology, clinical pharmacology

    2024  Volume 40, Issue 1, Page(s) 1–2

    Language English
    Publishing date 2024-03-14
    Publishing country India
    Document type Editorial
    ZDB-ID 1401760-x
    ISSN 0970-9185
    ISSN 0970-9185
    DOI 10.4103/joacp.joacp_80_24
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: When gut meets the heart: Chronic atrial and intestinal dysrhythmia presenting as chronic intestinal pseudo-obstruction, an uncommon cohesinopathy.

    Yadav, Abhishek / Garg, Amit Kumar / Veerwal, Hardik / Bhatia, Prateek / Bhattacharya, Anish / Sharma, Vishal

    Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology

    2024  

    Language English
    Publishing date 2024-02-02
    Publishing country India
    Document type Letter
    ZDB-ID 632595-6
    ISSN 0975-0711 ; 0254-8860
    ISSN (online) 0975-0711
    ISSN 0254-8860
    DOI 10.1007/s12664-024-01521-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Telescreening of Diabetic Retinopathy

    Bhatia, Vishal

    Journal of Social Health and Diabetes

    2019  Volume 07, Issue 01, Page(s) 31–32

    Language English
    Publishing date 2019-06-01
    Publisher Thieme Medical and Scientific Publishers Private Ltd.
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 2733669-4
    ISSN 2321-0664 ; 2321-0656 ; 2321-0664
    ISSN (online) 2321-0664
    ISSN 2321-0656 ; 2321-0664
    DOI 10.1055/s-0039-1683465
    Database Thieme publisher's database

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  5. Article: Vibrio

    Chaudhary, Naveen / Mohan, Balvinder / Kaur, Harpreet / Modgil, Vinay / Kant, Vishal / Bhatia, Alka / Taneja, Neelam

    Antibiotics (Basel, Switzerland)

    2023  Volume 12, Issue 6

    Abstract: Cholera, a disease of antiquity, is still festering in developing countries that lack safe drinking water and sewage disposal. ...

    Abstract Cholera, a disease of antiquity, is still festering in developing countries that lack safe drinking water and sewage disposal.
    Language English
    Publishing date 2023-06-14
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2681345-2
    ISSN 2079-6382
    ISSN 2079-6382
    DOI 10.3390/antibiotics12061046
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Catecholamines' accumulation and their disturbed metabolism at perilesional site: a possible cause of vitiligo progression.

    Tanwar, Sushma / Thakur, Vishal / Bhatia, Alka / Parsad, Davinder

    Archives of dermatological research

    2022  Volume 315, Issue 2, Page(s) 173–180

    Abstract: Catecholamines (epinephrine, norepinephrine and dopamine) are considered toxic to the melanocytes and may play an important role in the development of depigmented patches on the skin. This study was done to evaluate the levels of catecholamines in skin ... ...

    Abstract Catecholamines (epinephrine, norepinephrine and dopamine) are considered toxic to the melanocytes and may play an important role in the development of depigmented patches on the skin. This study was done to evaluate the levels of catecholamines in skin and plasma samples of active vitiligo patients' and gene expression changes in catecholamines' metabolism regulatory genes (COMT and GTPCH1), immunoregulatory genes (CTLA4 and PTPN22), and Catalase in active vitiligo patients. In this single-centre, prospective, case-control study, 30 patients with active vitiligo were recruited and skin biopsies from the perilesional site and plasma samples were collected. Skin biopsies from the normal site in vitiligo patients and healthy controls (n = 15) and plasma samples from controls were also obtained. Catecholamines' estimation was done via high-performance liquid chromatography. Gene expression variations were investigated via reverse transcription-polymerase chain reaction (PCR) and real-time PCR. Epinephrine, norepinephrine and dopamine levels were significantly higher in perilesional skin biopsies as compared to controls (P = 0.035, 0.024, and 0.006, respectively). However, epinephrine, norepinephrine and dopamine levels observed in patients' plasma samples were comparable to controls. The mRNA expression level of the Catalase gene was found to be upregulated at the perilesional site of patients as compared to the non-affected site of same patients (P < 0.001) and healthy controls (P = 0.037). Transcriptional expression of GTPCH1 and COMT were observed to be increased significantly at the perilesional site of patients in comparison to controls (P = 0.004 and P = 0.046, respectively). Our results support the presence of oxidative stress, inflammation and induced immune response in vitiligo patients at the perilesional sites. The increased inflammatory response may lead to catecholamines upregulation resulting in oxidative stress and melanocyte damage.
    MeSH term(s) Humans ; Vitiligo ; Catecholamines/metabolism ; Catalase/genetics ; Catalase/metabolism ; Dopamine/metabolism ; Case-Control Studies ; Prospective Studies ; Melanocytes/metabolism ; Epinephrine/metabolism ; Norepinephrine/metabolism ; Protein Tyrosine Phosphatase, Non-Receptor Type 22
    Chemical Substances Catecholamines ; Catalase (EC 1.11.1.6) ; Dopamine (VTD58H1Z2X) ; Epinephrine (YKH834O4BH) ; Norepinephrine (X4W3ENH1CV) ; PTPN22 protein, human (EC 3.1.3.48) ; Protein Tyrosine Phosphatase, Non-Receptor Type 22 (EC 3.1.3.48)
    Language English
    Publishing date 2022-02-28
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 130131-7
    ISSN 1432-069X ; 0340-3696
    ISSN (online) 1432-069X
    ISSN 0340-3696
    DOI 10.1007/s00403-022-02333-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Unilateral chilblains affecting the lower limb with post-polio residual paralysis: An example of immunocompromised cutaneous district.

    Bhatia, Riti / Arava, Sudheer / Gupta, Vishal

    Indian journal of dermatology, venereology and leprology

    2021  Volume 87, Issue 4, Page(s) 558–559

    MeSH term(s) Adult ; Chilblains/diagnosis ; Chilblains/etiology ; Humans ; Immunocompromised Host ; Lower Extremity ; Male ; Paralysis/complications ; Postpoliomyelitis Syndrome/complications ; Postpoliomyelitis Syndrome/immunology
    Language English
    Publishing date 2021-12-16
    Publishing country United States
    Document type Case Reports ; Letter
    ZDB-ID 416068-x
    ISSN 0973-3922 ; 0019-5162 ; 0378-6323
    ISSN (online) 0973-3922
    ISSN 0019-5162 ; 0378-6323
    DOI 10.25259/IJDVL_541_20
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Microbial alchemy: upcycling of brewery spent grains into high-value products through fermentation.

    Ahuja, Vishal / Chauhan, Shikha / Purewal, Sukhvinder Singh / Mehariya, Sanjeet / Patel, Anil Kumar / Kumar, Gopalakrishnan / Megharaj, Mallavarapu / Yang, Yung-Hun / Bhatia, Shashi Kant

    Critical reviews in biotechnology

    2024  , Page(s) 1–19

    Abstract: Spent grains are one of the lignocellulosic biomasses available in abundance, discarded by breweries as waste. The brewing process generates around 25-30% of waste in different forms and spent grains alone account for 80-85% of that waste, resulting in a ...

    Abstract Spent grains are one of the lignocellulosic biomasses available in abundance, discarded by breweries as waste. The brewing process generates around 25-30% of waste in different forms and spent grains alone account for 80-85% of that waste, resulting in a significant global waste volume. Despite containing essential nutrients, i.e., carbohydrates, fibers, proteins, fatty acids, lipids, minerals, and vitamins, efficient and economically viable valorization of these grains is lacking. Microbial fermentation enables the valorization of spent grain biomass into numerous commercially valuable products used in energy, food, healthcare, and biomaterials. However, the process still needs more investigation to overcome challenges, such as transportation, cost-effective pretreatment, and fermentation strategy. to lower the product cost and to achieve market feasibility and customer affordability. This review summarizes the potential of spent grains valorization
    Language English
    Publishing date 2024-01-01
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 1042364-3
    ISSN 1549-7801 ; 0738-8551
    ISSN (online) 1549-7801
    ISSN 0738-8551
    DOI 10.1080/07388551.2023.2286430
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Revolutionizing diabetes care: unveiling tirzepatide's potential in glycemic control and beyond.

    Sood, Aayushi / Kaur, Purnoor / Syed, Omar / Sood, Akshit / Aronow, Wilbert S / Borokhovsky, Benjamin / Bhatia, Vishal / Gupta, Rahul

    Expert review of clinical pharmacology

    2024  Volume 17, Issue 3, Page(s) 235–246

    Abstract: Introduction: Diabetes is a global public health challenge with rising prevalence. This review explores current diabetes understanding, diagnostic and management guidelines, economic impact, and lifestyle modifications as the primary approach.: Areas ... ...

    Abstract Introduction: Diabetes is a global public health challenge with rising prevalence. This review explores current diabetes understanding, diagnostic and management guidelines, economic impact, and lifestyle modifications as the primary approach.
    Areas covered: Focusing on pharmacological interventions, we discuss the roles of GLP-1 agonists and GLP/GIP agonists in diabetes management and cardiovascular risk reduction. Tirzepatide, a novel medication, is highlighted for its unique mechanism of action. Clinical trials demonstrate its effectiveness in glucose control, weight reduction, and its potential impact on diabetes, obesity, NASH, and cardiovascular risks.
    Expert opinion: Tirzepatide shows promise in diabetes treatment, offering glucose control and weight loss. It also holds potential for addressing comorbidities. However, cautious use is vital due to potential adverse effects and contraindications, including hypersensitivity reactions, pregnancy, and breastfeeding precautions. This review underscores tirzepatide as a valuable addition to diabetes therapies, with evolving prospects for enhanced patient outcomes as research advances.
    MeSH term(s) Female ; Pregnancy ; Humans ; Glycemic Control ; Blood Glucose ; Diabetes Mellitus/drug therapy ; Gastric Inhibitory Polypeptide ; Diabetes Mellitus, Type 2/drug therapy ; Glucagon-Like Peptide-1 Receptor ; Hypoglycemic Agents/adverse effects ; Glucagon-Like Peptide-2 Receptor
    Chemical Substances tirzepatide (OYN3CCI6QE) ; Blood Glucose ; Gastric Inhibitory Polypeptide (59392-49-3) ; Glucagon-Like Peptide-1 Receptor ; Hypoglycemic Agents ; Glucagon-Like Peptide-2 Receptor
    Language English
    Publishing date 2024-01-31
    Publishing country England
    Document type Journal Article ; Review
    ISSN 1751-2441
    ISSN (online) 1751-2441
    DOI 10.1080/17512433.2024.2310070
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Down-conversion luminescence nanocomposites based on nitrogen-doped carbon quantum dots@bioplastic for applications in optical displays, LEDs and UVC tubes.

    Dutt Sharma, Varun / Kansay, Vishal / Chandan, G / Bhatia, Anita / Kumar, Nikhil / Chakrabarti, S / Bera, M K

    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy

    2024  Volume 312, Page(s) 124065

    Abstract: Carbon quantum dots (CQDs)-based composites as luminous down-conversion materials are becoming more popular due to several advantages such as steady fluorescence, ease of functionalization, tailoring of emission in the visible range, and so on. We report ...

    Abstract Carbon quantum dots (CQDs)-based composites as luminous down-conversion materials are becoming more popular due to several advantages such as steady fluorescence, ease of functionalization, tailoring of emission in the visible range, and so on. We report an inexpensive and environmentally sustainable synthesis of fluorescent nitrogen doped-CQDs produced from Cissus quadrangularis, a low-cost plant precursor with therapeutic value. The morphological, structural, and physicochemical features of the material were carefully investigated. Under UV stimulation (365 nm), almost spherical shaped N-CQDs with an average diameter of 5.1 nm were discovered to generate yellow-green fluorescence, have excellent photostability, and strong water solubility, with a quantum yield of up to 5 %. Furthermore, as a solid-phase dispersion matrix for CQDs, ecologically friendly and biodegradable bioplastic is appealing. The down-conversion of solid-state fluorescence of LEDs and UVC tubes was demonstrated by creating a nanocomposite by inserting N-CQDs into the solid matrix of a wheat starch-based bioplastic. Furthermore, employing constructed quantum dot-based optical displays, down-converted LEDs, and UVC tubes, the impacts of varied CQD concentrations and pH sensitivity were examined.
    Language English
    Publishing date 2024-02-22
    Publishing country England
    Document type Journal Article
    ZDB-ID 210413-1
    ISSN 1873-3557 ; 0370-8322 ; 0584-8539 ; 1386-1425
    ISSN (online) 1873-3557
    ISSN 0370-8322 ; 0584-8539 ; 1386-1425
    DOI 10.1016/j.saa.2024.124065
    Database MEDical Literature Analysis and Retrieval System OnLINE

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