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  1. Article: Higher excitations for an exponential multireference wavefunction Ansatz and single-reference based multireference coupled cluster Ansatz: application to model systems H(4), P(4), and BeH(2).

    Hanrath, Michael

    The Journal of chemical physics

    2008  Volume 128, Issue 15, Page(s) 154118

    Abstract: ... applied to the H(4), P(4), and BeH(2) model systems according to the recently published analysis ...

    Abstract This article reports on the convergence of the exponential multireference wavefunction Ansatz (MRexpT) [J. Chem. Phys. 123, 84102 (2005)] and the single-reference based multireference coupled cluster Ansatz [J. Chem. Phys. 94, 1229 (1991)] with respect to higher cluster excitations. The approaches are applied to the H(4), P(4), and BeH(2) model systems according to the recently published analysis by Evangelista et al. [J. Chem. Phys. 125, 154113 (2006)]. The results show both MRexpT and SRMRCC to be highly accurate although SRMRCC shows problems due to its lack of Fermi vacuum invariance (symmetry breaking).
    Language English
    Publishing date 2008-04-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 3113-6
    ISSN 1089-7690 ; 0021-9606
    ISSN (online) 1089-7690
    ISSN 0021-9606
    DOI 10.1063/1.2899645
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  2. Article ; Online: Deposition of platelet RANTES triggering monocyte recruitment requires P-selectin and is involved in neointima formation after arterial injury.

    Schober, Andreas / Manka, David / von Hundelshausen, Philipp / Huo, Yuqing / Hanrath, Peter / Sarembock, Ian J / Ley, Klaus / Weber, Christian

    Circulation

    2002  Volume 106, Issue 12, Page(s) 1523–1529

    Abstract: ... Although the involvement of P-selectin in these processes is evident from studies in knockout mice, it has not been ... elucidated whether delivery of platelet chemokines requires P-selectin, thus serving as a P-selectin ... static preincubation of platelets and appear to depend on interactions of platelet but not endothelial P ...

    Abstract Background: Chemokines expressed on atherosclerotic endothelium or deposited by activated platelets have been implicated in monocyte recruitment during atherogenesis and restenosis. Although the involvement of P-selectin in these processes is evident from studies in knockout mice, it has not been elucidated whether delivery of platelet chemokines requires P-selectin, thus serving as a P-selectin-dependent effector function.
    Methods and results: Using immunofluorescence and laminar flow assays, we found that the deposition of the platelet-derived chemokine RANTES and monocyte arrest subsequently triggered by RANTES immobilized on inflamed endothelium are more efficient after preperfusion than after static preincubation of platelets and appear to depend on interactions of platelet but not endothelial P-selectin. This was revealed by the effects of P-selectin antibodies and comparison of P-selectin-deficient and wild-type platelets. Immunohistochemistry detected a substantial luminal expression of RANTES on neointimal lesions in wire-injured carotid arteries of apolipoprotein E (apoE)-deficient mice but not of mice with a combined deficiency in apoE and P-selectin (or platelet P-selectin). As assessed by histomorphometry, treatment of apoE-deficient mice with the RANTES receptor antagonist Met-RANTES markedly reduced neointimal plaque area and macrophage infiltration.
    Conclusions: Our data suggest that RANTES deposition and subsequent monocyte arrest are promoted by platelet P-selectin and involved in wire-induced intimal hyperplasia, and that blocking RANTES receptors attenuates neointima formation and macrophage infiltration. This mechanism represents an important component explaining the protection against neointimal growth in P-selectin-deficient mice and may represent a novel approach to the treatment of restenosis or atherosclerosis by the administration of chemokine receptor antagonists.
    MeSH term(s) Animals ; Apolipoproteins E/genetics ; Arterial Occlusive Diseases/etiology ; Arterial Occlusive Diseases/metabolism ; Arterial Occlusive Diseases/pathology ; Blood Platelets/physiology ; Carotid Artery Diseases/etiology ; Carotid Artery Diseases/metabolism ; Carotid Artery Diseases/pathology ; Cell Line ; Cell Movement ; Cells, Cultured ; Chemokine CCL5/analogs & derivatives ; Chemokine CCL5/analysis ; Chemokine CCL5/metabolism ; Chemokine CCL5/pharmacology ; Chemokine CCL5/physiology ; Endothelium, Vascular/physiology ; Humans ; Lipids/analysis ; Macrophages/physiology ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Monocytes/physiology ; P-Selectin/genetics ; P-Selectin/physiology ; Receptors, CCR5 ; Receptors, Chemokine/antagonists & inhibitors
    Chemical Substances Apolipoproteins E ; Chemokine CCL5 ; Lipids ; P-Selectin ; RANTES, Met- ; Receptors, CCR5 ; Receptors, Chemokine
    Language English
    Publishing date 2002-09-17
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, P.H.S.
    ZDB-ID 80099-5
    ISSN 1524-4539 ; 0009-7322 ; 0069-4193 ; 0065-8499
    ISSN (online) 1524-4539
    ISSN 0009-7322 ; 0069-4193 ; 0065-8499
    DOI 10.1161/01.cir.0000028590.02477.6f
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  3. Book ; Conference proceedings: Abstract book / 2nd Symposium on Stress Echocardiography

    Hanrath, P.

    Leipzig, 20.2.1993

    1993  

    Institution Symposium on Stress Echocardiography
    Author's details [chairmen: P. Hanrath ...]
    Keywords Echocardiography / congresses ; Exercise Test / congresses ; Dobutamine / diagnostic use / congresses ; Dipyridamole / diagnostic use / congresses
    Language English
    Size [14] S.
    Publisher Esaote Biomedica
    Publishing place S.l.
    Document type Book ; Conference proceedings
    HBZ-ID HT006156707
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    1994 A 755 order for loan Magazin

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  4. Article: Hand-assisted laparoscopic technique for removal of ovarian tumors in standing mares. [Erratum: July 15, 2002, v. 221 (2), p. 272.]

    Rodgerson, D.H / Brown, M.P / Watt, B.C / Keoughan, C.G / Hanrath, M

    Journal of the American Veterinary Medical Association. May 15, 2002. v. 220 (10)

    2002  

    Keywords mares ; ovaries ; neoplasms ; laparoscopy ; ovariectomy ; complications
    Language English
    Dates of publication 2002-0515
    Size p. 1503-1507.
    Document type Article
    ZDB-ID 390811-2
    ISSN 1943-569X ; 0003-1488
    ISSN (online) 1943-569X
    ISSN 0003-1488
    Database NAL-Catalogue (AGRICOLA)

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  5. Article ; Online: Pioneers in cardiology: Peter Hanrath, MD. Interview by Emma Wilkinson.

    Hanrath, Peter

    Circulation

    2007  Volume 116, Issue 5, Page(s) f25–6

    MeSH term(s) Cardiology/history ; Computer Systems ; Echocardiography, Three-Dimensional/history ; Echocardiography, Three-Dimensional/instrumentation ; Echocardiography, Transesophageal/history ; Echocardiography, Transesophageal/instrumentation ; Endoscopes/history ; Equipment Design ; Germany ; Heart Diseases/diagnostic imaging ; History, 20th Century ; Humans
    Language English
    Publishing date 2007-07-31
    Publishing country United States
    Document type Biography ; Historical Article ; Interview ; Portraits
    ZDB-ID 80099-5
    ISSN 1524-4539 ; 0009-7322 ; 0069-4193 ; 0065-8499
    ISSN (online) 1524-4539
    ISSN 0009-7322 ; 0069-4193 ; 0065-8499
    DOI 10.1161/CIRCULATIONAHA.107.185739
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Bioelectronic Platform to Investigate Charge Transfer between Photoexcited Quantum Dots and Microbial Outer Membranes.

    Suri, Mokshin / Mohamed, Zeinab / Bint E Naser, Samavi Farnush / Mao, Xianwen / Chen, Peng / Daniel, Susan / Hanrath, Tobias

    ACS applied materials & interfaces

    2022  Volume 14, Issue 13, Page(s) 15799–15810

    Abstract: Photosynthetic semiconductor biohybrids (PSBs) convert light energy to chemical energy through photo-driven charge transfer from nanocrystals to microorganisms that perform bioreactions of interest. Initial proof-of-concept PSB studies with an emphasis ... ...

    Abstract Photosynthetic semiconductor biohybrids (PSBs) convert light energy to chemical energy through photo-driven charge transfer from nanocrystals to microorganisms that perform bioreactions of interest. Initial proof-of-concept PSB studies with an emphasis on enhanced CO
    MeSH term(s) Electrodes ; Nanostructures ; Oxidation-Reduction ; Quantum Dots ; Semiconductors
    Language English
    Publishing date 2022-03-28
    Publishing country United States
    Document type Journal Article
    ISSN 1944-8252
    ISSN (online) 1944-8252
    DOI 10.1021/acsami.1c25032
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  7. Article: Weist "COMET" in die richtige Richtung?--Pro.

    Hanrath, P

    Deutsche medizinische Wochenschrift (1946)

    2003  Volume 128, Issue 50, Page(s) 2666

    Title translation Is "COMET" pointing in the right direction?--Pro.
    MeSH term(s) Adrenergic beta-Antagonists/therapeutic use ; Carbazoles/therapeutic use ; Cardiomyopathy, Dilated/drug therapy ; Dose-Response Relationship, Drug ; Heart Rate/drug effects ; Humans ; Metoprolol/therapeutic use ; Propanolamines/therapeutic use ; Treatment Outcome
    Chemical Substances Adrenergic beta-Antagonists ; Carbazoles ; Propanolamines ; carvedilol (0K47UL67F2) ; Metoprolol (GEB06NHM23)
    Language German
    Publishing date 2003-12-12
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 200446-x
    ISSN 1439-4413 ; 0012-0472
    ISSN (online) 1439-4413
    ISSN 0012-0472
    DOI 10.1055/s-2003-45486
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  8. Article ; Online: Single-cell multimodal imaging uncovers energy conversion pathways in biohybrids.

    Fu, Bing / Mao, Xianwen / Park, Youngchan / Zhao, Zhiheng / Yan, Tianlei / Jung, Won / Francis, Danielle H / Li, Wenjie / Pian, Brooke / Salimijazi, Farshid / Suri, Mokshin / Hanrath, Tobias / Barstow, Buz / Chen, Peng

    Nature chemistry

    2023  Volume 15, Issue 10, Page(s) 1400–1407

    Abstract: Microbe-semiconductor biohybrids, which integrate microbial enzymatic synthesis with the light-harvesting capabilities of inorganic semiconductors, have emerged as promising solar-to-chemical conversion systems. Improving the electron transport at the ... ...

    Abstract Microbe-semiconductor biohybrids, which integrate microbial enzymatic synthesis with the light-harvesting capabilities of inorganic semiconductors, have emerged as promising solar-to-chemical conversion systems. Improving the electron transport at the nano-bio interface and inside cells is important for boosting conversion efficiencies, yet the underlying mechanism is challenging to study by bulk measurements owing to the heterogeneities of both constituents. Here we develop a generalizable, quantitative multimodal microscopy platform that combines multi-channel optical imaging and photocurrent mapping to probe such biohybrids down to single- to sub-cell/particle levels. We uncover and differentiate the critical roles of different hydrogenases in the lithoautotrophic bacterium Ralstonia eutropha for bioplastic formation, discover this bacterium's surprisingly large nanoampere-level electron-uptake capability, and dissect the cross-membrane electron-transport pathways. This imaging platform, and the associated analytical framework, can uncover electron-transport mechanisms in various types of biohybrid, and potentially offers a means to use and engineer R. eutropha for efficient chemical production coupled with photocatalytic materials.
    MeSH term(s) Electron Transport ; Multimodal Imaging
    Language English
    Publishing date 2023-07-27
    Publishing country England
    Document type Journal Article ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 2464596-5
    ISSN 1755-4349 ; 1755-4330
    ISSN (online) 1755-4349
    ISSN 1755-4330
    DOI 10.1038/s41557-023-01285-z
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  9. Article ; Online: Re-entrant transition as a bridge of broken ergodicity in confined monolayers of hexagonal prisms and cylinders.

    Prajwal, B P / Huang, Jen-Yu / Ramaswamy, Meera / Stroock, Abraham D / Hanrath, Tobias / Cohen, Itai / Escobedo, Fernando A

    Journal of colloid and interface science

    2021  Volume 607, Issue Pt 2, Page(s) 1478–1490

    Abstract: The entropy-driven monolayer assembly of hexagonal prisms and cylinders was studied under hard slit confinement. At the conditions investigated, the particles have two distinct and dynamically disconnected rotational states: unflipped and flipped, ... ...

    Abstract The entropy-driven monolayer assembly of hexagonal prisms and cylinders was studied under hard slit confinement. At the conditions investigated, the particles have two distinct and dynamically disconnected rotational states: unflipped and flipped, depending on whether their circular/hexagonal face is parallel or perpendicular to the wall plane. Importantly, these two rotational states cast distinct projection areas over the wall plane that favor either hexagonal or tetragonal packing. Monte Carlo simulations revealed a re-entrant melting transition where an intervening disordered Flipped-Unflipped (FUN) phase is sandwiched between a fourfold tetratic phase at high concentrations and a sixfold triangular solid at intermediate concentrations. The FUN phase contains a mixture of flipped and unflipped particles and is translationally and orientationally disordered. Complementary experiments were conducted with photolithographically fabricated cylindrical microparticles confined in a wedge cell. Both simulations and experiments show the formation of phases with comparable fraction of flipped particles and structure, i.e., the FUN phase, triangular solid, and tetratic phase, indicating that both approaches sample analogous basins of particle-orientation phase-space. The phase behavior of hexagonal prisms in a soft-repulsive wall model was also investigated to exemplify how tunable particle-wall interactions can provide an experimentally viable strategy to dynamically bridge the flipped and unflipped states.
    Language English
    Publishing date 2021-09-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 241597-5
    ISSN 1095-7103 ; 0021-9797
    ISSN (online) 1095-7103
    ISSN 0021-9797
    DOI 10.1016/j.jcis.2021.09.073
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    Z 71/707: Show issues

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  10. Article ; Online: Insulten door interactie van anti-epileptica met rifampicine.

    Hanrath, Maarten A / Swart, Eleonora L

    Nederlands tijdschrift voor geneeskunde

    2014  Volume 158, Page(s) A7707

    Abstract: Background: Anti-epileptic drugs (AEDs) have a small therapeutic window, so it is important to monitor plasma levels. Inadequate plasma levels may lead to convulsions. Many AEDs are cleared hepatically, and there are many drug interactions that are ... ...

    Title translation Convulsions due to an interaction between anti-epileptic drugs and rifampicin.
    Abstract Background: Anti-epileptic drugs (AEDs) have a small therapeutic window, so it is important to monitor plasma levels. Inadequate plasma levels may lead to convulsions. Many AEDs are cleared hepatically, and there are many drug interactions that are known to lead to changes in plasma levels.
    Case description: A 54-year-old woman with known epilepsy developed convulsions after using rifampicin and flucloxacillin, despite the use of maintenance treatment in the form of carbamazepine, valproic acid and clonazepam. Since rifampicin is known to induce several cytochrome P450 enzymes and clearance of the anti-epileptic drug used may be affected by this, it can be assumed that the convulsions were caused by rifampicin. This interaction is however not mentioned in the Dutch 'G-standard' database.
    Conclusion: Rifampicin is known to be a strong inducer of various cytochrome P450 enzymes. This case description shows that the use of rifampicin may lead to convulsions. For this reason, these interactions should be included in the Dutch G-standard database.
    MeSH term(s) Anticonvulsants/adverse effects ; Anticonvulsants/therapeutic use ; Carbamazepine/therapeutic use ; Clonazepam/adverse effects ; Clonazepam/therapeutic use ; Cytochrome P-450 Enzyme System/drug effects ; Cytochrome P-450 Enzyme System/metabolism ; Drug Interactions ; Epilepsy/drug therapy ; Female ; Floxacillin/adverse effects ; Floxacillin/therapeutic use ; Humans ; Middle Aged ; Rifampin/adverse effects ; Rifampin/therapeutic use ; Seizures/chemically induced ; Seizures/drug therapy ; Valproic Acid/therapeutic use
    Chemical Substances Anticonvulsants ; Carbamazepine (33CM23913M) ; Floxacillin (43B2M34G2V) ; Clonazepam (5PE9FDE8GB) ; Valproic Acid (614OI1Z5WI) ; Cytochrome P-450 Enzyme System (9035-51-2) ; Rifampin (VJT6J7R4TR)
    Language Dutch
    Publishing date 2014
    Publishing country Netherlands
    Document type Case Reports ; English Abstract ; Journal Article
    ZDB-ID 82073-8
    ISSN 1876-8784 ; 0028-2162
    ISSN (online) 1876-8784
    ISSN 0028-2162
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