LIVIVO - Search results -

Search results

Result 1 - 10 of total 47179

Search options

Article: Traditional Chinese Medicine Shi-Bi-Man ameliorates psoriasis via inhibiting IL-23/Th17 axis and CXCL16-mediated endothelial activation.

Zhang, Chenyang / Cao, Xinran / Zhao, Lixin / Ni, Zitong / Du, Haojie / Qu, Jiao / Zhu, Jianxia / Sun, Haiyan / Sun, Yang / Ouyang, Zijun

Chinese medicine

2024 Volume 19, Issue 1, Page(s) 38

Abstract: ... profile. Shi-Bi-Man (SBM) is a safe herbal supplement sourced from various natural plants, including ...

Abstract	Background: Psoriasis is a chronic inflammatory genetic disease, mainly manifesting in the skin. Conventional therapies, such as glucocorticosteroids and corticosteroids, have adverse effects that limit drug use. Hence, it is imperative to identify a new therapeutic strategy that exhibits a favorable safety profile. Shi-Bi-Man (SBM) is a safe herbal supplement sourced from various natural plants, including ginseng, angelica sinensis, polygonum multiflorum, and aloe vera. Purpose: We aimed to find a potential treatment for psoriasis and investigate the underlying mechanism through which SBM alleviates psoriatic-like skin inflammation in mice. Methods: We investigated the effects of supplementing with SBM through intragastric administration or smear administration in a murine model of imiquimod-induced psoriasis. The changes in body weight and Psoriasis Area and Severity Index (PASI) score were recorded throughout the entire process. Additionally, we used hematoxylin-eosin staining to observe the skin structure and performed single-cell RNA sequencing to explore the underlying mechanism of SBM in influencing the psoriasis-like phenotype. Immunofluorescence was conducted to verify our findings. Furthermore, reverse transcription-quantitative polymerase chain reaction (RT-qPCR) was employed to investigate the impact of Tetrahydroxy stilbene glycoside (TSG) on the expression levels of IL23 in HaCaT cells. Results: SBM remarkably alleviated the psoriasis-like phenotype by inhibiting IL-23/Th17 cell axis. Single-cell RNA sequencing analysis revealed a decrease in the expression of Il17 and Il23 in keratinocytes and T cells, concomitant with a reduction in the proportion of Th17 cells. Meanwhile, the activation of endothelial cells was inhibited, accompanied by a decrease in the expression of Cxcl16. In vitro, the addition of TSG to HaCaT cells resulted in significant suppression of IL23 expression stimulated by tumor necrosis factor-alpha (TNF-α).
Language	English
Publishing date	2024-03-01
Publishing country	England
Document type	Journal Article
ZDB-ID	2260322-0
ISSN	1749-8546
ISSN	1749-8546
DOI	10.1186/s13020-024-00907-z
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Article ; Online: Qing-Re-Chu-shi decoction ameliorates 2,4-dinitrochlorobenzene-induced atopic dermatitis in NC/Nga mice through anti-inflammation and immunoregulatory mechanisms.

Meng, YuJiao / Liu, Yu / Guo, Jianning / Guo, Xiaoyao / Han, Xuyang / Zhang, Lu / Di, Tingting / Zhao, Jingxia / Wang, Yan / Li, Ping

Journal of ethnopharmacology

2024 Volume 323, Page(s) 117702

Abstract: Ethnopharmacological relevance: Qing-Re-Chu-Shi Decoction (QRCSD), a traditional Chinese herbal ...

Abstract	Ethnopharmacological relevance: Qing-Re-Chu-Shi Decoction (QRCSD), a traditional Chinese herbal formula, has been employed as a complementary and alternative therapy for inflammatory skin diseases. However, its active constituents and the mechanistic basis of its action on atopic dermatitis remain in adequately understood. Aim of the study: Atopic dermatitis (AD) is an allergic dermatitis marked by eczematous lesions and pruritus. The study aimed to elucidate the underlying effects of QRCSD on AD and to identify the components responsible for its therapeutic efficacy in a mouse model. Materials and methods: Network pharmacology and UPLC-mass analysis were used to anticipate the pharmacological mechanisms and to identify active components of QRCSD, respectively. A DNCB-induced AD-like model was established in NC/Nga mice. QRCSD or prednisolone (as a positive control) was administered via gavage every other day from day14 to day 21. Dermatitis severity score, scratching behavior, skin barrier function, spleen index, Th1/Th2 lymphocyte ratio, and serum IgE levels were evaluated. Protein arrays, including 40 inflammatory cytokines, were performed on skin lesions, followed by confirmation experiments of Western blotting in dorsal skin lesions. Results: The construction of a QRCSD-AD-Network and topological analysis firstly proposed potential targets of QRCSD acting on AD. Animal experiments demonstrated that oral administration of QRCSD ameliorated AD-like lesions, reduced epidermal thickness and mast cell count, decreased serum IgE levels, augmented tight junction protein (Claudin 1, Occludin) levels, and regulated the Th1/Th2 balance in the spleen, as well as spleen index. Elevated levels of interleukin (IL)-4, IL-5, IL-6, IL-17, and Eotaxin were revealed in AD-like skin lesions by protein arrays. Western blotting confirmed that the phosphorylation levels of ERK, P38, JNK, STAT3 and P65 were downregulated, and IL-6 expression was also reduced following QRCSD treatment. Conclusions: The study enhances the understanding of the anti-inflammatory and immunomodulatory effects of QRCSD, showcasing its significant protective role against atopic dermatitis. Treatment with QRCSD may be considered as a viable candidate for complementary and alternative therapy in managing atopic dermatitis.
MeSH term(s)	Mice ; Animals ; Dermatitis, Atopic/chemically induced ; Dermatitis, Atopic/drug therapy ; Dermatitis, Atopic/pathology ; Dinitrochlorobenzene/toxicity ; Skin/pathology ; Interleukin-6/metabolism ; Cytokines/metabolism ; Anti-Inflammatory Agents/adverse effects ; Immunoglobulin E
Chemical Substances	Dinitrochlorobenzene ; Interleukin-6 ; Cytokines ; Anti-Inflammatory Agents ; Immunoglobulin E (37341-29-0)
Language	English
Publishing date	2024-01-03
Publishing country	Ireland
Document type	Journal Article
ZDB-ID	134511-4
ISSN	1872-7573 ; 0378-8741
ISSN (online)	1872-7573
ISSN	0378-8741
DOI	10.1016/j.jep.2024.117702
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 1494: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article: Study on the Mechanism of Qing-Fei-Shen-Shi Decoction on Asthma Based on Integrated 16S rRNA Sequencing and Untargeted Metabolomics.

Hu, Haibo / Zhao, Guojing / Wang, Kun / Han, Ping / Ye, Haiyan / Wang, Fengchan / Liu, Na / Zhou, Peixia / Lu, Xuechao / Zhou, Zhaoshan / Cui, Huantian

Evidence-based complementary and alternative medicine : eCAM

2023 Volume 2023, Page(s) 1456844

Abstract: Qing-Fei-Shen-Shi decoction (QFSS) consists of ...

Abstract	Qing-Fei-Shen-Shi decoction (QFSS) consists of
Language	English
Publishing date	2023-02-15
Publishing country	United States
Document type	Journal Article
ZDB-ID	2171158-6
ISSN	1741-4288 ; 1741-427X
ISSN (online)	1741-4288
ISSN	1741-427X
DOI	10.1155/2023/1456844
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 5995: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Huanglian Jiedu Wan intervened with "Shi-Re Shanghuo" syndrome through regulating immune balance mediated by biomarker succinate.

Luo, Keke / Zhao, Haiyu / Wang, Mengxiao / Tian, Mengyao / Si, Nan / Xia, Wen / Song, Jianfang / Chen, Yunqin / Wang, Linna / Zhang, Yan / Wei, Xiaolu / Li, Xing / Qin, Guangyuan / Yang, Jiaying / Wang, Hongjie / Bian, Baolin / Zhou, Yanyan

Clinical immunology (Orlando, Fla.)

2023 Volume 258, Page(s) 109861

Abstract: With increasing stress in daily life and work, subhealth conditions induced by "Shi-Re Shanghuo ... approved for the treatment of "Shi-Re Shanghuo" with promising clinical efficacy. Preliminary small-sample ... However, the correlation and underlying mechanism between these biomarkers of HLJDW intervention on "Shi-Re Shanghuo ...

Abstract	With increasing stress in daily life and work, subhealth conditions induced by "Shi-Re Shanghuo" syndrome was gradually universal. "Huanglian Jiedu Wan" (HLJDW) was the first new syndrome Chinese medicine approved for the treatment of "Shi-Re Shanghuo" with promising clinical efficacy. Preliminary small-sample clinical studies have identified some notable biomarkers (succinate, 4-hydroxynonenal, etc.). However, the correlation and underlying mechanism between these biomarkers of HLJDW intervention on "Shi-Re Shanghuo" syndrome remained ambiguous. Therefore, this study was designed as a randomized, double-blind, multicenter, placebo-controlled Phase II clinical trial, employing integrated analysis techniques such as non-targeted and targeted metabolomics, salivary microbiota, proteomics, parallel peaction monitoring, molecular docking and surface plasmon resonance (SPR). The results of the correlation analysis indicated that HLJDW could mediate the balance between inflammation and immunity through succinate produced via host and microbial source to intervene "Shi-Re Shanghuo" syndrome. Further through the HIF1α/MMP9 pathway, succinate regulated downstream arachidonic acid metabolism, particularly the lipid peroxidation product 4-hydroxynonenal. Finally, an animal model of recurrent oral ulcers induced by "Shi-Re Shang Huo" was established and HLJDW was used for intervention, key essential indicators (succinate, glutamine, 4-hydroxynonenal, arachidonic acid metabolism) essential in the potential pathway HIF1α/MMP9 discovered in clinical practice were validated. The results were found to be consistent with our clinical findings. Taken together, succinate was observed as an important signal that triggered immune responses, which might serve as a key regulatory metabolic switch or marker of "Shi-Re Shanghuo" syndrome treated with HLJDW.
MeSH term(s)	Animals ; Arachidonic Acid ; Biomarkers ; Drugs, Chinese Herbal ; Matrix Metalloproteinase 9 ; Molecular Docking Simulation ; Succinates/therapeutic use ; Succinic Acid ; Humans
Chemical Substances	4-hydroxy-2-nonenal (K1CVM13F96) ; Arachidonic Acid (27YG812J1I) ; Biomarkers ; Drugs, Chinese Herbal ; huanglian-jie-du decoction ; Matrix Metalloproteinase 9 (EC 3.4.24.35) ; Succinates ; Succinic Acid (AB6MNQ6J6L)
Language	English
Publishing date	2023-12-06
Publishing country	United States
Document type	Clinical Trial, Phase II ; Journal Article ; Multicenter Study ; Randomized Controlled Trial ; Research Support, Non-U.S. Gov't
ZDB-ID	1459903-x
ISSN	1521-7035 ; 1521-6616
ISSN (online)	1521-7035
ISSN	1521-6616
DOI	10.1016/j.clim.2023.109861
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 880: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article: Real-World Study on Chai-Shi-Jie-Du Granules for the Treatment of Dengue Fever and the Possible Mechanisms Based on Network Pharmacology.

Yang, Huiqin / Ma, Dehong / Li, Qin / Zhou, Wen / Chen, Hongyi / Shan, Xiyun / Zheng, Haipeng / Luo, Chun / Ou, Zhiyue / Xu, Jielan / Wang, Changtai / Zhao, Lingzhai / Su, Rui / Chen, Yuehong / Liu, Qingquan / Tan, Xinghua / Lin, Luping / Jiang, Tao / Zhang, Fuchun

Evidence-based complementary and alternative medicine : eCAM

2023 Volume 2023, Page(s) 9942842

Abstract: ... for dengue fever. This real-world study aimed to evaluate the effects of Chai-Shi-Jie-Du (CSJD) granules ...

Abstract	Objectives: Traditional Chinese medicine (TCM) is a widely used method for treating dengue fever in China. TCM improves the symptoms of patients with dengue, but there is no standard TCM prescription for dengue fever. This real-world study aimed to evaluate the effects of Chai-Shi-Jie-Du (CSJD) granules for the treatment of dengue fever and the underlying mechanisms. Methods: We implemented a multicenter real-world study, an Results: 137 pairs of patients were successfully matched according to age, sex, and the time from onset to presentation. The time to defervescence (1.7 days vs. 2.5 days, Conclusions: CSJD granules exhibit high potential for the treatment of dengue fever, and the therapeutic mechanisms involved could be related to regulating immunity, moderating the oxidative stress response, and the response to lipopolysaccharide.
Language	English
Publishing date	2023-08-30
Publishing country	United States
Document type	Journal Article
ZDB-ID	2171158-6
ISSN	1741-4288 ; 1741-427X
ISSN (online)	1741-4288
ISSN	1741-427X
DOI	10.1155/2023/9942842
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 5995: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Correction: Shi, H., et al. Arctigenin Attenuates Breast Cancer Progression through Decreasing GM-CSF/TSLP/STAT3/β-Catenin Signaling.

Shi, Hui / Zhao, Luping / Guo, Xinlin / Fang, Runping / Zhang, Hui / Dong, Guanjun / Fu, Jia / Yan, Fenglian / Zhang, Junfeng / Ning, Zhaochen / Ma, Qun / Li, Zhihua / Li, Chunxia / Dai, Jun / Si, Chuanping / Xiong, Huabao

International journal of molecular sciences

2020 Volume 21, Issue 22

Abstract: The authors wish to make the following correction to this paper [ ... ]. ...

Abstract	The authors wish to make the following correction to this paper [...].
Language	English
Publishing date	2020-11-23
Publishing country	Switzerland
Document type	Published Erratum
ZDB-ID	2019364-6
ISSN	1422-0067 ; 1422-0067 ; 1661-6596
ISSN (online)	1422-0067
ISSN	1422-0067 ; 1661-6596
DOI	10.3390/ijms21228850
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article: Anticoccidial Effect of Herbal Powder "Shi Ying Zi" in Chickens Infected with

Song, Xu / Li, Yunhe / Chen, Shufan / Jia, Renyong / Huang, Yongyuan / Zou, Yuanfeng / Li, Lixia / Zhao, Xinxin / Yin, Zhongqiong

Animals : an open access journal from MDPI

2020 Volume 10, Issue 9

Abstract: ... are urgently needed. This study presents an anticoccidial herbal powder "Shi Yin Zi", which consists of ...

Abstract	Coccidiosis is one of the most economically important diseases affecting the poultry industry. Currently, anticoccidial drugs used in veterinary clinics show many deficiencies, and new control measures are urgently needed. This study presents an anticoccidial herbal powder "Shi Yin Zi", which consists of
Language	English
Publishing date	2020-08-24
Publishing country	Switzerland
Document type	Journal Article
ISSN	2076-2615
ISSN	2076-2615
DOI	10.3390/ani10091484
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Genome-Wide Analysis of the Shi-Related Sequence Family and Functional Identification of

Zhao, Shu-Ping / Song, Xin-Yuan / Guo, Lin-Lin / Zhang, Xiang-Zhan / Zheng, Wei-Jun

International journal of molecular sciences

2020 Volume 21, Issue 5

Abstract: The plant- ... ...

Abstract	The plant-special
MeSH term(s)	Adaptation, Physiological ; Droughts ; Gene Expression Regulation, Plant ; Genome, Plant ; Plant Proteins/genetics ; Plant Proteins/metabolism ; Salinity ; Glycine max/genetics ; Glycine max/growth & development ; Glycine max/metabolism ; Stress, Physiological
Chemical Substances	Plant Proteins
Language	English
Publishing date	2020-03-06
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2019364-6
ISSN	1422-0067 ; 1422-0067 ; 1661-6596
ISSN (online)	1422-0067
ISSN	1422-0067 ; 1661-6596
DOI	10.3390/ijms21051810
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Effects of traditional Chinese medicine formula Le-Cao-Shi on hepatitis B: In vivo and in vitro studies.

Zhao, Qing / Ren, Xia / Chen, Min / Yue, Shi-Jun / Zhang, Meng-Qi / Chen, Kai-Xian / Guo, Yue-Wei / Shao, Chang-Lun / Wang, Chang-Yun

Journal of ethnopharmacology

2019 Volume 244, Page(s) 112132

Abstract: Ethnopharmacological relevance: Formula Le-Cao-Shi (LCS) is a traditional Chinese medicine (TCM ...

Abstract	Ethnopharmacological relevance: Formula Le-Cao-Shi (LCS) is a traditional Chinese medicine (TCM), which has long been used as a folk remedy against hepatitis B in China. The present study was conducted to evaluate the anti-hepatitis B effects of aqueous extract of LCS in vivo and in vitro. Materials and method: we investigated the anti-HBV effects of LCS in vivo and in vitro with duck hepatitis B model and HepG2.2.15 cell line model, respectively. The serologic and cellular biomarkers and the histopathological changes were examined. Results: By a duck hepatitis B model, the extract of LCS was found to restrain the expressions of duck hepatitis B surface antigen (DHBsAg), hepatitis B e antigen (DHBeAg), and HBV-DNA (DHBV-DNA). Moreover, LCS could decrease the levels of aspartate and alanine aminotransferases (AST and ALT) and ameliorate duck liver histological lesions. Correspondingly, in a HepG2.2.15 cellular model, LCS could also significantly inhibit the secretions of HBsAg and HBeAg. Conclusion: LCS exerted potent anti-hepatitis effects against the infection of HBV. The above results demonstrated the first-hand experimental evidences for the anti-hepatitis B efficiency of LCS. Our study provides a basis for further exploration and development of this promising compound prescription to treat hepatitis B disease.
MeSH term(s)	Animals ; Antiviral Agents/pharmacology ; Antiviral Agents/therapeutic use ; Cell Line, Tumor ; Cell Survival/drug effects ; DNA, Viral ; Drugs, Chinese Herbal/therapeutic use ; Ducks ; Hepatitis B/drug therapy ; Hepatitis B/immunology ; Hepatitis B/pathology ; Hepatitis B/virology ; Hepatitis B Surface Antigens/immunology ; Hepatitis B Virus, Duck/drug effects ; Hepatitis B Virus, Duck/genetics ; Hepatitis B Virus, Duck/immunology ; Hepatitis B e Antigens/immunology ; Hepatitis, Viral, Animal/drug therapy ; Hepatitis, Viral, Animal/immunology ; Hepatitis, Viral, Animal/pathology ; Hepatitis, Viral, Animal/virology ; Humans ; Liver/drug effects ; Liver/pathology ; Medicine, Chinese Traditional
Chemical Substances	Antiviral Agents ; DNA, Viral ; Drugs, Chinese Herbal ; Hepatitis B Surface Antigens ; Hepatitis B e Antigens ; Le-Cao-Shi
Language	English
Publishing date	2019-08-02
Publishing country	Ireland
Document type	Journal Article
ZDB-ID	134511-4
ISSN	1872-7573 ; 0378-8741
ISSN (online)	1872-7573
ISSN	0378-8741
DOI	10.1016/j.jep.2019.112132
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 1494: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Combination of Hua Shi Bai Du granule (Q-14) and standard care in the treatment of patients with coronavirus disease 2019 (COVID-19): A single-center, open-label, randomized controlled trial.

Liu, Jia / Yang, Wei / Liu, Yue / Lu, Cheng / Ruan, Lianguo / Zhao, Chen / Huo, Ruili / Shen, Xin / Miao, Qing / Lv, Wenliang / Li, Hao / Shi, Huaxin / Hu, Lijie / Yang, Zhixu / Zhang, Li / Wang, Bing / Dong, Guoju / Xian, Yongyue / Li, Bin /

Zhou, Zhenqi / Xu, Chunyan / Chen, Yingying / Bian, Yongjun / Guo, Jing / Yang, Jinliang / Wang, Jian / Qi, Wensheng / Chen, Suping / Chen, Yang / Yan, Bei / Wang, Wei / Li, Jing / Xie, Xiaolei / Xu, Ming / Jiang, Jianxin / Wang, Gang / Cong, Xiaodong / Zhu, Haoning / Shi, Jiaheng / Leng, Luxing / Li, Dongxu / Guo, Lanping / Huang, Luqi

Phytomedicine : international journal of phytotherapy and phytopharmacology

2021 Volume 91, Page(s) 153671

Abstract: Objective: To evaluate the efficacy and safety of Hua Shi Bai Du Granule (Q-14) plus standard care ...

Abstract	Objective: To evaluate the efficacy and safety of Hua Shi Bai Du Granule (Q-14) plus standard care compared with standard care alone in adults with coronavirus disease (COVID-19). Study design: A single-center, open-label, randomized controlled trial. Setting: Wuhan Jinyintan Hospital, Wuhan, China, February 27 to March 27, 2020. Participants: A total of 204 patients with laboratory-confirmed COVID-19 were randomized into the treatment group and control group, consisting of 102 patients in each group. Interventions: In the treatment group, Q-14 was administered at 10 g (granules) twice daily for 14 days, plus standard care. In the control group, patients were provided standard care alone for 14 days. Main outcome measure: The primary outcome was the conversion time for the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral assay. Adverse events were analyzed in the safety population. Results: Among the 204 patients, 195 were analyzed according to the intention-to-treat principle. A total of 149 patients (71 vs. 78 in the treatment and control groups, respectively) tested negative via the SARS-CoV-2 viral assay. There was no statistical significance in the conversion time between the treatment group and control group (Full analysis set: Median [interquartile range]: 10.00 [9.00-11.00] vs. 10.00 [9.00-11.00]; Mean rank: 67.92 vs. 81.44; P = 0.051). The recovery time for fever was shorter in the treatment group than in the control group. The disappearance rate of symptoms like cough, fatigue, and chest discomfort was significantly higher in the treatment group. In chest computed tomography (CT) examinations, the overall evaluation of chest CT examination after treatment compared with baseline showed that more patients improved in the treatment group. There were no significant differences in the other outcomes. Conclusion: The combination of Q-14 and standard care for COVID-19 was useful for the improvement of symptoms (such as fever, cough, fatigue, and chest discomfort), but did not result in a significantly higher probability of negative conversion in the SARS-CoV-2 viral assay. No serious adverse events were observed. Trial registration: ChiCTR2000030288.
MeSH term(s)	COVID-19/therapy ; China ; Drugs, Chinese Herbal/therapeutic use ; Female ; Humans ; Male ; Middle Aged ; Treatment Outcome
Chemical Substances	Drugs, Chinese Herbal ; huashi baidu
Language	English
Publishing date	2021-07-17
Publishing country	Germany
Document type	Journal Article ; Randomized Controlled Trial
ZDB-ID	1205240-1
ISSN	1618-095X ; 0944-7113
ISSN (online)	1618-095X
ISSN	0944-7113
DOI	10.1016/j.phymed.2021.153671
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 4115: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

To top

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito