LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 118

Search options

  1. Article: Giant cell arteritis and scleritis: A rare association.

    Zulfiqar, Abrar-Ahmad

    Caspian journal of internal medicine

    2022  Volume 13, Issue 3, Page(s) 642–645

    Abstract: Background: Giant cell arteritis (GCA) is a vasculitis of the large and medium-sized arteries in the elderly whose ischemic complications adversely affect the eye. The irreversible loss of visual acuity is most often related to acute anterior ischemic ... ...

    Abstract Background: Giant cell arteritis (GCA) is a vasculitis of the large and medium-sized arteries in the elderly whose ischemic complications adversely affect the eye. The irreversible loss of visual acuity is most often related to acute anterior ischemic optic neuropathy. Very few cases of scleritis have been described in the literature.
    Case presentation: The patient presented an obvious case of giant cell arteritis, initially revealed by an ophthalmologic involvement in the form of posterior scleritis, an ear, nose, and throat (ENT) involvement with vestibular and neurological involvement with a type of peripheral neuropathy, all evolving in the context of a weight loss of 8 kg and a marked biological inflammatory syndrome. The patient presented several relapses of giant cell arteritis in the form of several episodes of anterior and posterior, right and left, and even bilateral, isolated scleritis without any other clinical or biological abnormalities, always in conjunction with a decrease in corticosteroid therapy. In the presence of corticosteroid dependence and resistance to methotrexate, tocilizumab was initiated.
    Conclusion: The therapeutic management of scleritis associated with giant cell arteritis is difficult. In the absence of a codified scheme, the treatment remains empirical, based on the experience of the various teams. In this context, biotherapies (anti-IL6 type, such as tocilizumab) are increasingly used.
    Language English
    Publishing date 2022-06-01
    Publishing country Iran
    Document type Case Reports
    ZDB-ID 2971933-1
    ISSN 2008-6172 ; 2008-6164
    ISSN (online) 2008-6172
    ISSN 2008-6164
    DOI 10.22088/cjim.13.3.642
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  2. Article: Creation of a new frailty scale in primary care: the Zulfiqar Frailty Scale.

    Zulfiqar, Abrar-Ahmad

    Caspian journal of internal medicine

    2022  Volume 13, Issue 2, Page(s) 425–430

    Abstract: ... of the "Zulfiqar Frailty Scale" (ZFS) tool to detect frailty as defined by Fried's criteria among a group ... to Fried's criteria was 32.5%. The prevalence of frailty according to the "Zulfiqar Frailty Scale" tool was ... of 91.0%.: Conclusion: The "Zulfiqar Frailty Scale" tool measures frailty just as effectively ...

    Abstract Background: Preventing dependency is a public health objective. We want to evaluate the ability of the "Zulfiqar Frailty Scale" (ZFS) tool to detect frailty as defined by Fried's criteria among a group of patients aged 75 and older.
    Methods: Prospective study conducted in Poitou-Charentes (France) for 12 months on patients aged 75 and over and considered autonomous in terms of the ADL scale. To be eligible, the patients could not reside in a nursing home and needed an ADL score of 4 or higher.
    Results: Among the group of 200 patients (with a mean age of 81.4 years, +/- 4.82), the prevalence of frailty according to Fried's criteria was 32.5%. The prevalence of frailty according to the "Zulfiqar Frailty Scale" tool was 35.0% and all items except home confinement were significantly associated with frailty. With this tool, the threshold for identifying frailty was 3 out of 6 criteria. It was quick (average completion time of 2 minutes and 2 seconds) with a sensitivity score of 88.0% and a negative predictive value of 91.0%.
    Conclusion: The "Zulfiqar Frailty Scale" tool measures frailty just as effectively as Fried's criteria, with sensitivity and negative predictive values no lower than the latter.
    Language English
    Publishing date 2022-07-29
    Publishing country Iran
    Document type Journal Article
    ZDB-ID 2971933-1
    ISSN 2008-6172 ; 2008-6164
    ISSN (online) 2008-6172
    ISSN 2008-6164
    DOI 10.22088/cjim.13.2.425
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  3. Article: Creation of a New Frailty Scale in Primary Care: The Zulfiqar Frailty Scale (ZFS).

    Zulfiqar, Abrar-Ahmad

    Medicines (Basel, Switzerland)

    2021  Volume 8, Issue 4

    Abstract: Introduction: ...

    Abstract Introduction:
    Language English
    Publishing date 2021-04-13
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2777965-8
    ISSN 2305-6320
    ISSN 2305-6320
    DOI 10.3390/medicines8040019
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  4. Article ; Online: Creation of a new frailty scale in primary care

    Abrar-Ahmad Zulfiqar

    Caspian Journal of Internal Medicine, Vol 13, Iss 2, Pp 425-

    the Zulfiqar frailty scale.

    2022  Volume 430

    Abstract: ... of the “Zulfiqar Frailty Scale” (ZFS) tool to detect frailty as defined by Fried's criteria among a group ... was 32.5%. The prevalence of frailty according to the “Zulfiqar Frailty Scale” tool was 35.0% and ... with a sensitivity score of 88.0% and a negative predictive value of 91.0%. Conclusion: The “Zulfiqar Frailty Scale ...

    Abstract Background: Preventing dependency is a public health objective. We want to evaluate the ability of the “Zulfiqar Frailty Scale” (ZFS) tool to detect frailty as defined by Fried's criteria among a group of patients aged 75 and older. Methods: Prospective study conducted in Poitou-Charentes (France) for 12 months on patients aged 75 and over and considered autonomous in terms of the ADL scale. To be eligible, the patients could not reside in a nursing home and needed an ADL score of 4 or higher. Results: Among the group of 200 patients (with a mean age of 81.4 years, +/- 4.82), the prevalence of frailty according to Fried's criteria was 32.5%. The prevalence of frailty according to the “Zulfiqar Frailty Scale” tool was 35.0% and all items except home confinement were significantly associated with frailty. With this tool, the threshold for identifying frailty was 3 out of 6 criteria. It was quick (average completion time of 2 minutes and 2 seconds) with a sensitivity score of 88.0% and a negative predictive value of 91.0%. Conclusion: The “Zulfiqar Frailty Scale” tool measures frailty just as effectively as Fried’s criteria, with sensitivity and negative predictive values no lower than the latter.
    Keywords frailty ; elderly ; general medicine ; zulfiqar frailty scale (zfs) ; Internal medicine ; RC31-1245
    Subject code 616
    Language English
    Publishing date 2022-02-01T00:00:00Z
    Publisher Babol University of Medical Sciences
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

  5. Article: Frailty in Primary Care: Validation of the simplified Zulfiqar Frailty Scale (sZFS).

    Zulfiqar, Abrar-Ahmad

    Medicines (Basel, Switzerland)

    2021  Volume 8, Issue 9

    Abstract: ... scale for the early and rapid detection of frailty syndrome, called the simplified Zulfiqar Frailty ...

    Abstract Introduction: Frailty scales are used very rarely by general practitioners as they are time consuming and are not well-adapted to current needs. Thus, we have designed with general practitioners a new scale for the early and rapid detection of frailty syndrome, called the simplified Zulfiqar Frailty Scale (sZFS).
    Patients and methods: This scale was tested in two general medicine practices in Normandy (France) for a total of six months and compared to the GFST tool "The Gerontopole Frailty Screening Tool". Only patients who were over 65 years old with an ADL ≥ 4/6 were included.
    Results: 107 were patients included in the general medicine practice, with an average age of 74 years. The sZFS questionnaire has a shorter administration time than the GFST questionnaire (
    Conclusion: Our frailty screening scale is simple, relevant, and quick.
    Language English
    Publishing date 2021-09-03
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2777965-8
    ISSN 2305-6320
    ISSN 2305-6320
    DOI 10.3390/medicines8090051
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  6. Article: Validation of the Zulfiqar Frailty Scale (ZFS): A New Tool for General Practitioners.

    Zulfiqar, Abrar-Ahmad

    Medicines (Basel, Switzerland)

    2021  Volume 8, Issue 9

    Abstract: Introduction: The early detection of frailty, a frequent transient state that can be reversible in the elderly and is responsible for significant morbidity and mortality, helps prevent complications from it.: Objective: To evaluate the performance of ...

    Abstract Introduction: The early detection of frailty, a frequent transient state that can be reversible in the elderly and is responsible for significant morbidity and mortality, helps prevent complications from it.
    Objective: To evaluate the performance of the "ZFS" tool to screen for frailty as defined SEGA scale criteria in an ambulatory population of patients at least 65 years of age.
    Methods: A prospective non-interventional study conducted in Alsace for a duration of six months that included patients aged 65 and over, judged to be autonomous with an ADL > 4/6.
    Results: In this ambulatory population of 102 patients with an average age of 76 years, frailty, according to modified SEGA criteria grid A, had a prevalence of 19.6%. Frailty, according to the "ZFS" tool, had a prevalence of 35.0%, and all of its elements except weight loss were significantly associated with frailty. Its threshold for identifying frailty is three criteria out of six. It was rapid (average completion time: 87 s), had a sensitivity of 100%, and a negative predictive value of 100%.
    Conclusions: The "ZFS" tool makes it possible to screen for frailty with a high level of sensitivity and a negative predictive value.
    Language English
    Publishing date 2021-09-04
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2777965-8
    ISSN 2305-6320
    ISSN 2305-6320
    DOI 10.3390/medicines8090052
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  7. Article ; Online: Validation of the Zulfiqar Frailty Scale (ZFS)

    Abrar-Ahmad Zulfiqar

    Medicines, Vol 8, Iss 52, p

    A New Tool for General Practitioners

    2021  Volume 52

    Abstract: Introduction: The early detection of frailty, a frequent transient state that can be reversible in the elderly and is responsible for significant morbidity and mortality, helps prevent complications from it. Objective: To evaluate the performance of the “ ...

    Abstract Introduction: The early detection of frailty, a frequent transient state that can be reversible in the elderly and is responsible for significant morbidity and mortality, helps prevent complications from it. Objective: To evaluate the performance of the “ZFS” tool to screen for frailty as defined SEGA scale criteria in an ambulatory population of patients at least 65 years of age. Methods: A prospective non-interventional study conducted in Alsace for a duration of six months that included patients aged 65 and over, judged to be autonomous with an ADL > 4/6. Results: In this ambulatory population of 102 patients with an average age of 76 years, frailty, according to modified SEGA criteria grid A, had a prevalence of 19.6%. Frailty, according to the “ZFS” tool, had a prevalence of 35.0%, and all of its elements except weight loss were significantly associated with frailty. Its threshold for identifying frailty is three criteria out of six. It was rapid (average completion time: 87 s), had a sensitivity of 100%, and a negative predictive value of 100%. Conclusions: The “ZFS” tool makes it possible to screen for frailty with a high level of sensitivity and a negative predictive value.
    Keywords ZULFIQAR Frailty Scale (ZFS) ; modified SEGA scale grid A ; primary care ; prevention ; elderly subjects ; Medicine ; R
    Language English
    Publishing date 2021-09-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

  8. Article ; Online: Creation of a New Frailty Scale in Primary Care

    Abrar-Ahmad Zulfiqar

    Medicines, Vol 8, Iss 19, p

    The Zulfiqar Frailty Scale (ZFS)

    2021  Volume 19

    Abstract: ... for use in primary care, referred to as the Zulfiqar Frailty Scale (ZFS). This scale was tested ...

    Abstract Very few frailty scales are used by general practitioners as they are time consuming and cumbersome. We designed a new scale for the rapid detection of frailty. Methods: We developed a frailty screening tool for use in primary care, referred to as the Zulfiqar Frailty Scale (ZFS). This scale was tested in a general practitioner’s office for six months in Plancoët, France. Only patients over 75 years of age with Activities of Daily Living (ADL) ≥4 were included. The objective of this research was to validate the scale, evaluate its performance, and compare this screening tool with other scales such as the Fried Scale, the Gerontopole Frailty Screening Tool (GFST), the modified Short Emergency Geriatric Assessment (mSEGA) Grid A, and the Comprehensive Geriatric Assessment (CGA). Results: A total of 102 patients were included, with a mean age of 82.65 ± 4.79; 55 were women and 47 were men. The percentage of frail subjects was 63.7% in our scale, 67.7% in the mSEGA grid A, 75.5% in the GFST, and 60.8% for the Fried criteria. After a comprehensive geriatric assessment, frailty syndrome was found in 57 patients (55.9%). In general, both scales showed solid performance, and differences between them in the sample were minimal. As the CGA showed a prevalence of frailty of 55.9%, a similar prevalence threshold for the ZFS (i.e., 64% at the threshold ≥3 could be assessed). The completion time for our scale was less than two minutes, and staff required no training beforehand. Its sensitivity was 83.9%, and its specificity was 67.5%. Its positive predictive value was 80%, and its negative predictive value was 73%. The Pearson correlations between the geriatric scores were all strong and roughly equivalent to each other. Conclusions: Our frailty screening scale is simple, relevant, and rapid (taking less than two minutes).
    Keywords frailty ; elderly ; primary care ; Zulfiqar Frailty Scale (ZFS) ; Medicine ; R
    Language English
    Publishing date 2021-04-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

  9. Article ; Online: Frailty in Primary Care

    Abrar-Ahmad Zulfiqar

    Medicines, Vol 8, Iss 51, p

    Validation of the simplified Zulfiqar Frailty Scale (sZFS)

    2021  Volume 51

    Abstract: ... scale for the early and rapid detection of frailty syndrome, called the simplified Zulfiqar Frailty ...

    Abstract Introduction: Frailty scales are used very rarely by general practitioners as they are time consuming and are not well-adapted to current needs. Thus, we have designed with general practitioners a new scale for the early and rapid detection of frailty syndrome, called the simplified Zulfiqar Frailty Scale (sZFS). Patients and methods: This scale was tested in two general medicine practices in Normandy (France) for a total of six months and compared to the GFST tool “The Gerontopole Frailty Screening Tool”. Only patients who were over 65 years old with an ADL ≥ 4/6 were included. Results: 107 were patients included in the general medicine practice, with an average age of 74 years. The sZFS questionnaire has a shorter administration time than the GFST questionnaire ( p < 0.001). Its sensitivity is of 93%, and its specificity is 58%. Its positive predictive value is 57%, and its negative predictive value is 93%. The area under the curve of the sZFS scale is 0.83 [0.76; 0.91] (IC95%). Conclusion: Our frailty screening scale is simple, relevant, and quick.
    Keywords frailty syndrome ; primary care ; sZFS tool ; GFST scale ; Medicine ; R
    Language English
    Publishing date 2021-09-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

  10. Article ; Online: [No title information]

    Zulfiqar, Abrar-Ahmad / Andrès, Emmanuel

    Geriatrie et psychologie neuropsychiatrie du vieillissement

    2022  Volume 20, Issue 1, Page(s) 28–34

    Abstract: Résumé L'activité physique et sa réalisation chez le sujet âgé demeurent une problématique importante. De nombreuses études ont permis de montrer des bénéfices physiques et psychiques sur la qualité de vie et sur la mortalité. Le maintien d'une activité ... ...

    Title translation Activité physique et gériatrie : revue de littérature.
    Abstract Résumé L'activité physique et sa réalisation chez le sujet âgé demeurent une problématique importante. De nombreuses études ont permis de montrer des bénéfices physiques et psychiques sur la qualité de vie et sur la mortalité. Le maintien d'une activité physique régulière est déterminant pour conserver les capacités fonctionnelles nécessaires aux activités de la vie quotidienne et préserver la qualité de vie des sujets âgés. Abstract Physical activity and its performance in the elderly remain a major problem. Numerous studies have shown physical and psychological benefits on quality of life and mortality. Maintaining regular physical activity is a key to maintain the functional abilities necessary for activities of daily living and preserve the quality of life of the elderly.
    MeSH term(s) Activities of Daily Living ; Aged ; Exercise ; Geriatrics ; Humans ; Quality of Life
    Language French
    Publishing date 2022-06-02
    Publishing country France
    Document type Journal Article ; Review
    ISSN 2115-7863
    ISSN (online) 2115-7863
    DOI 10.1684/pnv.2021.1002
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

To top