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  1. Article ; Online: The Emergency Department Safety Net for Obstetric/Gynecologic Emergencies.

    Guest, Brittany / Dubbs, Sarah B

    Emergency medicine clinics of North America

    2023  Volume 41, Issue 2, Page(s) xv–xvi

    MeSH term(s) Pregnancy ; Female ; Humans ; Emergencies ; Pregnancy Complications ; Emergency Service, Hospital
    Language English
    Publishing date 2023-04-06
    Publishing country United States
    Document type Editorial
    ZDB-ID 605637-4
    ISSN 1558-0539 ; 0733-8627
    ISSN (online) 1558-0539
    ISSN 0733-8627
    DOI 10.1016/j.emc.2023.02.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1919: Show issues Location:
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  2. Article ; Online: Hyperosmolar Hyperglycemic State.

    Lovegrove, Spencer S / Dubbs, Sarah B

    Emergency medicine clinics of North America

    2023  Volume 41, Issue 4, Page(s) 687–696

    Abstract: Hyperosmolar hyperglycemic state (HHS) is an underrecognized diabetic emergency with high morbidity and mortality. Many features of HHS overlap with those of diabetic ketoacidosis but key differentiators for HHS are serum osmolality greater than 320 mOsm/ ...

    Abstract Hyperosmolar hyperglycemic state (HHS) is an underrecognized diabetic emergency with high morbidity and mortality. Many features of HHS overlap with those of diabetic ketoacidosis but key differentiators for HHS are serum osmolality greater than 320 mOsm/kg, lack of metabolic acidosis, and minimal to no presence of ketones. HHS is often triggered by an underlying illness-most commonly infection but may also be triggered by stroke, acute coronary syndrome, and other acute illnesses. Treatment guidelines recommend aggressive volume-repletion of osmotic losses in addition to insulin therapy, plus treatment of the underlying cause.
    Language English
    Publishing date 2023-08-19
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 605637-4
    ISSN 1558-0539 ; 0733-8627
    ISSN (online) 1558-0539
    ISSN 0733-8627
    DOI 10.1016/j.emc.2023.07.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Immune-based Therapies-What the Emergency Physician Needs to Know.

    Dubbs, Sarah B / Falat, Cheyenne / Rosenblatt, Lauren

    Immunology and allergy clinics of North America

    2023  Volume 43, Issue 3, Page(s) 569–582

    Abstract: Immunotherapy is a treatment modality that has a broad and rapidly growing range of applications to treat both chronic and acute diseases, including rheumatoid arthritis, Crohn disease, cancer, and COVID-19. Emergency physicians must be aware of the ... ...

    Abstract Immunotherapy is a treatment modality that has a broad and rapidly growing range of applications to treat both chronic and acute diseases, including rheumatoid arthritis, Crohn disease, cancer, and COVID-19. Emergency physicians must be aware of the breadth of applications and be able to consider the effects of immunotherapies when patients on these treatments present to the hospital. This article provides a review of the mechanisms of action, indications for use, and potential complications of immunotherapy treatments that are relevant in the emergency care setting.
    MeSH term(s) Humans ; COVID-19/therapy ; COVID-19/etiology ; Neoplasms/therapy ; Immunotherapy/adverse effects ; Physicians
    Language English
    Publishing date 2023-07-03
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 92606-1
    ISSN 1557-8607 ; 0889-8561
    ISSN (online) 1557-8607
    ISSN 0889-8561
    DOI 10.1016/j.iac.2022.10.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Rapid Fire: Tumor Lysis Syndrome.

    Dubbs, Sarah B

    Emergency medicine clinics of North America

    2018  Volume 36, Issue 3, Page(s) 517–525

    Abstract: Tumor lysis syndrome (TLS) is a life-threatening oncologic emergency, characterized by a constellation of hyperkalemia, hyperuricemia, hyperphosphatemia, and hypocalcemia. The spectrum ranges from patients who are asymptomatic to those who go into ... ...

    Abstract Tumor lysis syndrome (TLS) is a life-threatening oncologic emergency, characterized by a constellation of hyperkalemia, hyperuricemia, hyperphosphatemia, and hypocalcemia. The spectrum ranges from patients who are asymptomatic to those who go into cardiac arrest and die. Prompt recognition and initiation of treatment by emergency physicians are key, especially in the early stages of the syndrome. This case-based review presents an overview of the key points in pathophysiology, diagnosis, and management of TLS that are key to emergency physicians.
    MeSH term(s) Disease Management ; Electrocardiography ; Humans ; Hyperkalemia/diagnosis ; Hyperkalemia/etiology ; Hyperuricemia/diagnosis ; Hyperuricemia/etiology ; Male ; Middle Aged ; Tumor Lysis Syndrome/complications ; Tumor Lysis Syndrome/diagnosis
    Language English
    Publishing date 2018-08
    Publishing country United States
    Document type Case Reports ; Journal Article ; Review
    ZDB-ID 605637-4
    ISSN 1558-0539 ; 0733-8627
    ISSN (online) 1558-0539
    ISSN 0733-8627
    DOI 10.1016/j.emc.2018.04.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1919: Show issues Location:
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  5. Article ; Online: The Latest Cancer Agents and Their Complications.

    Dubbs, Sarah B

    Emergency medicine clinics of North America

    2018  Volume 36, Issue 3, Page(s) 485–492

    Abstract: The latest cancer agents, collectively known as cancer immunotherapy, have tremendously increased the armamentarium against cancer. Their targeted mechanisms seem ideal, but they do come with complications. As these therapies become more widespread, ... ...

    Abstract The latest cancer agents, collectively known as cancer immunotherapy, have tremendously increased the armamentarium against cancer. Their targeted mechanisms seem ideal, but they do come with complications. As these therapies become more widespread, emergency physicians everywhere must be aware of the immune-related adverse events that can occur, and be ready to identify and coordinate treatment. This article provides the emergency physician with a brief introduction and overview of immunotherapy drugs and their complications.
    MeSH term(s) Antineoplastic Agents/adverse effects ; Antineoplastic Agents/therapeutic use ; Humans ; Immunologic Factors/adverse effects ; Immunologic Factors/therapeutic use ; Immunotherapy ; Neoplasms/therapy
    Chemical Substances Antineoplastic Agents ; Immunologic Factors
    Language English
    Publishing date 2018-08
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 605637-4
    ISSN 1558-0539 ; 0733-8627
    ISSN (online) 1558-0539
    ISSN 0733-8627
    DOI 10.1016/j.emc.2018.04.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Pediatric Hematologic and Oncologic Emergencies.

    Stephanos, Kathleen / Dubbs, Sarah B

    Emergency medicine clinics of North America

    2021  Volume 39, Issue 3, Page(s) 555–571

    Abstract: Pediatric hematologic and oncologic emergencies are in 3 major categories: complications of hematologic disorders, emergencies associated with the new onset of cancers, and treatment-associated oncologic emergencies. The overall number of these patients ... ...

    Abstract Pediatric hematologic and oncologic emergencies are in 3 major categories: complications of hematologic disorders, emergencies associated with the new onset of cancers, and treatment-associated oncologic emergencies. The overall number of these patients remains low; however, the mortality associated with these diseases remains high despite significant advances in management. This article presents a review of the most commonly encountered pediatric hematologic and oncologic complications that emergency physicians and providers need to know.
    MeSH term(s) Anemia, Sickle Cell/diagnosis ; Anemia, Sickle Cell/epidemiology ; Anemia, Sickle Cell/therapy ; Antineoplastic Agents/adverse effects ; Child ; Drug-Related Side Effects and Adverse Reactions/diagnosis ; Drug-Related Side Effects and Adverse Reactions/epidemiology ; Drug-Related Side Effects and Adverse Reactions/therapy ; Humans ; Incidence ; Neoplasms/diagnosis ; Neoplasms/epidemiology ; Neoplasms/therapy ; Pediatric Emergency Medicine ; Prevalence ; Purpura, Thrombocytopenic, Idiopathic/diagnosis ; Purpura, Thrombocytopenic, Idiopathic/epidemiology ; Purpura, Thrombocytopenic, Idiopathic/therapy
    Chemical Substances Antineoplastic Agents
    Language English
    Publishing date 2021-06-09
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 605637-4
    ISSN 1558-0539 ; 0733-8627
    ISSN (online) 1558-0539
    ISSN 0733-8627
    DOI 10.1016/j.emc.2021.04.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1919: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  7. Article ; Online: Evaluation and Management of Urinary Tract Infection in the Emergency Department.

    Dubbs, Sarah B / Sommerkamp, Sarah K

    Emergency medicine clinics of North America

    2019  Volume 37, Issue 4, Page(s) 707–723

    Abstract: Urinary tract infection (UTI) affects patients of all ages and is a diagnosis that emergency physicians might make multiple times per shift. This article reviews the evaluation and management of patients with infections of the urinary tract. Definitions ... ...

    Abstract Urinary tract infection (UTI) affects patients of all ages and is a diagnosis that emergency physicians might make multiple times per shift. This article reviews the evaluation and management of patients with infections of the urinary tract. Definitions of asymptomatic bacteriuria, uncomplicated UTI, and complicated UTI are presented, as well as techniques for distinguishing them. The pathophysiology and clinical and laboratory diagnoses of UTI are described. Treatment of UTI is reviewed, with attention to bacteriuria and special populations, including pregnant, elderly/geriatric, and spinal cord injury patients.
    MeSH term(s) Anti-Bacterial Agents/therapeutic use ; Bacteriuria/diagnosis ; Bacteriuria/therapy ; Cystitis/diagnosis ; Cystitis/therapy ; Emergency Service, Hospital ; Humans ; Pyelonephritis/diagnosis ; Pyelonephritis/therapy ; Urinary Tract Infections/diagnosis ; Urinary Tract Infections/therapy
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2019-08-19
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 605637-4
    ISSN 1558-0539 ; 0733-8627
    ISSN (online) 1558-0539
    ISSN 0733-8627
    DOI 10.1016/j.emc.2019.07.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: High risk and low prevalence diseases: Hemophilia emergencies.

    Alblaihed, Leen / Dubbs, Sarah B / Koyfman, Alex / Long, Brit

    The American journal of emergency medicine

    2022  Volume 56, Page(s) 21–27

    Abstract: ... by deficiency in factor VIII (in hemophilia A) or IX (in hemophilia B), which may result in severe bleeding ...

    Abstract Introduction: Hemophilia is a bleeding disorder due to coagulation pathway factor deficiency that is associated with significant morbidity and mortality.
    Objective: This review highlights the pearls and pitfalls of the emergency department (ED) evaluation of hemophilia, including diagnostic procedures, imaging, and management based on current evidence.
    Discussion: Hemophilia is marked by deficiency in factor VIII (in hemophilia A) or IX (in hemophilia B), which may result in severe bleeding. The severity of the disease depends upon factor levels. Patients with severe deficiency most commonly present in the first two years of life. Severe bleeding may include intracranial hemorrhage, retroperitoneal bleeding, large hematomas, bleeding within the chest or abdomen/pelvis, and subacute or delayed postpartum bleeding. ED management is the immediate replacement of clotting factors based on the suspicion of bleed rather than the confirmation of one. The doses for factor concentrate replacement to achieve factor levels of 100% are 50 U/kg for FVIII and 100 U/kg for FIX. The development of inhibitors can complicate the clinical picture and treatment possibilities. Consultation with the hematology specialist is recommended to assist with evaluation and management.
    Conclusion: Emergency physician knowledge of hemophilia, including the presentation, evaluation, and management, can improve the care of these patients.
    MeSH term(s) Blood Coagulation Factors/therapeutic use ; Emergencies ; Female ; Hemophilia A/diagnosis ; Hemophilia A/epidemiology ; Hemophilia A/therapy ; Hemophilia B/diagnosis ; Hemophilia B/drug therapy ; Hemorrhage/drug therapy ; Humans ; Prevalence
    Chemical Substances Blood Coagulation Factors
    Language English
    Publishing date 2022-02-28
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 605890-5
    ISSN 1532-8171 ; 0735-6757
    ISSN (online) 1532-8171
    ISSN 0735-6757
    DOI 10.1016/j.ajem.2022.02.045
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Immune-based Therapies-What the Emergency Physician Needs to Know.

    Dubbs, Sarah B / Falat, Cheyenne / Rosenblatt, Lauren

    Emergency medicine clinics of North America

    2021  Volume 40, Issue 1, Page(s) 135–148

    Abstract: Immunotherapy is a treatment modality that has a broad and rapidly growing range of applications to treat both chronic and acute diseases, including rheumatoid arthritis, Crohn disease, cancer, and COVID-19. Emergency physicians must be aware of the ... ...

    Abstract Immunotherapy is a treatment modality that has a broad and rapidly growing range of applications to treat both chronic and acute diseases, including rheumatoid arthritis, Crohn disease, cancer, and COVID-19. Emergency physicians must be aware of the breadth of applications and be able to consider the effects of immunotherapies when patients on these treatments present to the hospital. This article provides a review of the mechanisms of action, indications for use, and potential complications of immunotherapy treatments that are relevant in the emergency care setting.
    MeSH term(s) Emergency Medicine/methods ; Emergency Medicine/trends ; Humans ; Immunotherapy/adverse effects ; Immunotherapy/methods ; Immunotherapy/trends ; Review Literature as Topic
    Language English
    Publishing date 2021-10-29
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 605637-4
    ISSN 1558-0539 ; 0733-8627
    ISSN (online) 1558-0539
    ISSN 0733-8627
    DOI 10.1016/j.emc.2021.08.011
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: The Heme-Onc Tidal Wave: Are You Prepared?

    Kaide, Colin G / Dubbs, Sarah B

    Emergency medicine clinics of North America

    2018  Volume 36, Issue 3, Page(s) xv–xvi

    MeSH term(s) Delivery of Health Care/organization & administration ; Emergencies ; Emergency Service, Hospital/organization & administration ; Humans ; Neoplasms/complications ; Neoplasms/therapy
    Language English
    Publishing date 2018-08-06
    Publishing country United States
    Document type Editorial
    ZDB-ID 605637-4
    ISSN 1558-0539 ; 0733-8627
    ISSN (online) 1558-0539
    ISSN 0733-8627
    DOI 10.1016/j.emc.2018.05.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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