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  1. Article ; Online: Multisystem Inflammatory Syndrome in Children and Kawasaki Disease: Two Different Illnesses with Overlapping Clinical Features.

    Rowley, Anne H

    The Journal of pediatrics

    2020  Volume 224, Page(s) 129–132

    MeSH term(s) COVID-19/diagnosis ; COVID-19/physiopathology ; Child ; Child, Preschool ; Diagnosis, Differential ; Humans ; Infant ; Mucocutaneous Lymph Node Syndrome/diagnosis ; Mucocutaneous Lymph Node Syndrome/physiopathology ; Pandemics ; SARS-CoV-2 ; Systemic Inflammatory Response Syndrome/diagnosis ; Systemic Inflammatory Response Syndrome/physiopathology
    Keywords covid19
    Language English
    Publishing date 2020-06-22
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 3102-1
    ISSN 1097-6833 ; 0022-3476
    ISSN (online) 1097-6833
    ISSN 0022-3476
    DOI 10.1016/j.jpeds.2020.06.057
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Diagnosing Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Related Multisystem Inflammatory Syndrome in Children (MIS-C): Focus on the Gastrointestinal Tract and the Myocardium.

    Rowley, Anne H

    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

    2020  Volume 72, Issue 9, Page(s) e402–e403

    MeSH term(s) Amphibians ; Animals ; Brucella ; Brucellosis ; COVID-19 ; Child ; Gastrointestinal Tract ; Humans ; Myocardium ; SARS-CoV-2 ; Systemic Inflammatory Response Syndrome
    Keywords covid19
    Language English
    Publishing date 2020-07-25
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 1099781-7
    ISSN 1537-6591 ; 1058-4838
    ISSN (online) 1537-6591
    ISSN 1058-4838
    DOI 10.1093/cid/ciaa1080
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Understanding SARS-CoV-2-related multisystem inflammatory syndrome in children.

    Rowley, Anne H

    Nature reviews. Immunology

    2020  Volume 20, Issue 8, Page(s) 453–454

    MeSH term(s) Abdominal Pain/pathology ; Abdominal Pain/virology ; Betacoronavirus/pathogenicity ; COVID-19 ; Child ; Coronavirus Infections/pathology ; Coronavirus Infections/virology ; Heart Diseases/pathology ; Heart Diseases/virology ; Humans ; Inflammation/etiology ; Inflammation/pathology ; Mucocutaneous Lymph Node Syndrome/pathology ; Mucocutaneous Lymph Node Syndrome/virology ; Pandemics ; Pneumonia, Viral/pathology ; Pneumonia, Viral/virology ; SARS-CoV-2 ; Shock/pathology ; Shock/virology ; Systemic Inflammatory Response Syndrome/pathology ; Systemic Inflammatory Response Syndrome/virology
    Keywords covid19
    Language English
    Publishing date 2020-06-16
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Review
    ZDB-ID 2062776-2
    ISSN 1474-1741 ; 1474-1733
    ISSN (online) 1474-1741
    ISSN 1474-1733
    DOI 10.1038/s41577-020-0367-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: An Unintended Consequence of Pandemic Control Measures: Fewer Cases of Kawasaki Disease.

    Shulman, Stanford T / Rowley, Anne H

    The Journal of pediatrics

    2021  Volume 239, Page(s) 11–14

    MeSH term(s) COVID-19 ; Humans ; Mucocutaneous Lymph Node Syndrome/epidemiology ; Pandemics/prevention & control ; SARS-CoV-2
    Language English
    Publishing date 2021-08-26
    Publishing country United States
    Document type Editorial ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 3102-1
    ISSN 1097-6833 ; 0022-3476
    ISSN (online) 1097-6833
    ISSN 0022-3476
    DOI 10.1016/j.jpeds.2021.08.069
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Understanding SARS-CoV-2-related multisystem inflammatory syndrome in children

    Rowley, Anne H.

    Nature Reviews Immunology

    2020  Volume 20, Issue 8, Page(s) 453–454

    Keywords Immunology ; covid19
    Language English
    Publisher Springer Science and Business Media LLC
    Publishing country us
    Document type Article ; Online
    ZDB-ID 2062776-2
    ISSN 1474-1741 ; 1474-1733
    ISSN (online) 1474-1741
    ISSN 1474-1733
    DOI 10.1038/s41577-020-0367-5
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Diagnosing Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Related Multisystem Inflammatory Syndrome in Children (MIS-C)

    Rowley, Anne H

    Clinical Infectious Diseases ; ISSN 1058-4838 1537-6591

    Focus on the Gastrointestinal Tract and the Myocardium

    2020  

    Keywords Microbiology (medical) ; Infectious Diseases ; covid19
    Language English
    Publisher Oxford University Press (OUP)
    Publishing country uk
    Document type Article ; Online
    DOI 10.1093/cid/ciaa1080
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article: Current Insights Into the Pathophysiology of Multisystem Inflammatory Syndrome in Children.

    Vella, Laura A / Rowley, Anne H

    Current pediatrics reports

    2021  Volume 9, Issue 4, Page(s) 83–92

    Abstract: Purpose of review: We highlight the new clinical entity multisystem inflammatory syndrome in children (MIS-C), the progress in understanding its immunopathogenesis, and compare and contrast the clinical and immunologic features of MIS-C with Kawasaki ... ...

    Abstract Purpose of review: We highlight the new clinical entity multisystem inflammatory syndrome in children (MIS-C), the progress in understanding its immunopathogenesis, and compare and contrast the clinical and immunologic features of MIS-C with Kawasaki disease (KD).
    Recent findings: Studies show immune dysregulation in MIS-C including T lymphocyte depletion and activation, T cell receptor Vbeta skewing, elevated plasmablast frequencies, increased markers of vascular pathology, and decreased numbers and functional profiles of antigen-presenting cells.
    Summary: MIS-C is a late manifestation of infection with SARS-CoV-2 associated with marked immune activation and many potential mechanisms of immunopathogenesis. MIS-C and KD have clinical similarities but are distinct. Myocardial dysfunction with or without mild coronary artery dilation can occur in MIS-C but generally corrects within weeks. In contrast, the coronary arteries are the primary target in KD, and coronary artery sequelae can be lifelong. Supportive care and anti-inflammatory therapy appear to hasten improvement in children with MIS-C, and there is hope that vaccines will prevent its development.
    Language English
    Publishing date 2021-10-19
    Publishing country Germany
    Document type Journal Article ; Review
    ISSN 2167-4841
    ISSN 2167-4841
    DOI 10.1007/s40124-021-00257-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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