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  1. Article ; Online: Intravascular large B-cell lymphoma presented as hemophagocytic lymphohistiocytosis.

    Irigoín, Maria Victoria / Oliver, Carolina / Gualco, Gabriela / de Galvez, Gabriela

    Hematology, transfusion and cell therapy

    2021  Volume 45, Issue 1, Page(s) 116–118

    Language English
    Publishing date 2021-07-06
    Publishing country Brazil
    Document type Case Reports
    ISSN 2531-1387
    ISSN (online) 2531-1387
    DOI 10.1016/j.htct.2021.05.008
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  2. Article: Sarcoidosis pulmonar asociada a interferón pegilado en el tratamiento de la hepatitis C crónica.

    Ubiña-Aznar, E / Fernández-Moreno, N / Rivera-Irigoín, R / Navarro-Jarabo, J M / García-Fernández, G / Pérez-Aisa, A / Vera-Rivero, F / Fernández-Pérez, F / Moreno-Mejías, P / Méndez-Sánchez, I / de Sola-Earle, C / Sánchez-Cantos, A

    Gastroenterologia y hepatologia

    2005  Volume 28, Issue 8, Page(s) 450–452

    Abstract: Treatment with pegylated interferon is usually used in active chronic hepatitis C in association ... of pulmonary sarcoidosis induced by pegylated interferon in a 35 year-old woman with chronic hepatitis C who developed ...

    Title translation Pulmonary sarcoidosis associated with pegylated interferon in the treatment of chronic hepatitis C.
    Abstract Treatment with pegylated interferon is usually used in active chronic hepatitis C in association with ribavirin. The adverse effects of interferon include influenza-like syndrome and mild respiratory manifestations, which are highly frequent. Among the immunomodulatory effects is the possibility of inducing or exacerbating autoimmune phenomena such as cutaneous or systemic sarcoidosis. We present a new case of pulmonary sarcoidosis induced by pegylated interferon in a 35 year-old woman with chronic hepatitis C who developed respiratory symptoms 4 months after starting therapy with pegylated interferon associated with ribavirin. Radiological images showed a micronodular pattern in both pulmonary fields together with hilar and mediastinal adenopathies. Transbronchial biopsy confirmed the presence of sarcoidal granulomas. After the diagnosis of pulmonary sarcoidosis, antiviral therapy was suspended with subsequent resolution of the clinical symptoms.
    MeSH term(s) Adult ; Antiviral Agents/administration & dosage ; Antiviral Agents/adverse effects ; Antiviral Agents/therapeutic use ; Female ; Hepatitis C, Chronic/complications ; Hepatitis C, Chronic/drug therapy ; Humans ; Interferon-alpha/administration & dosage ; Interferon-alpha/adverse effects ; Interferon-alpha/pharmacology ; Interferon-alpha/therapeutic use ; Polyethylene Glycols/administration & dosage ; Polyethylene Glycols/adverse effects ; Polyethylene Glycols/therapeutic use ; Ribavirin/administration & dosage ; Ribavirin/therapeutic use ; Sarcoidosis, Pulmonary/chemically induced ; Sarcoidosis, Pulmonary/diagnostic imaging ; Th1 Cells/drug effects ; Th1 Cells/immunology ; Tomography, X-Ray Computed
    Chemical Substances Antiviral Agents ; Interferon-alpha ; Polyethylene Glycols (3WJQ0SDW1A) ; Ribavirin (49717AWG6K)
    Language Spanish
    Publishing date 2005-08-18
    Publishing country Spain
    Document type Case Reports ; Journal Article
    ZDB-ID 632502-6
    ISSN 0210-5705
    ISSN 0210-5705
    DOI 10.1157/13079006
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    In stock of ZB MED Cologne/Königswinter

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  3. Article: Lateralized Movements during the Mating Behavior, Which Are Associated with Sex and Sexual Experience, Increase the Mating Success in

    Calla-Quispe, Erika / Irigoin, Esperanza / Mansurova, Madina / Martel, Carlos / Ibáñez, Alfredo J

    Insects

    2023  Volume 14, Issue 10

    Abstract: In the present study, we explored the effects of displacement directionality in mating behavior (i.e., lateralized and non-lateralized movements) on mating success (i.e., copulation occurs) and efficiency (i.e., time length at which copulation is ... ...

    Abstract In the present study, we explored the effects of displacement directionality in mating behavior (i.e., lateralized and non-lateralized movements) on mating success (i.e., copulation occurs) and efficiency (i.e., time length at which copulation is achieved), and its association with sex and sexual experience in
    Language English
    Publishing date 2023-10-10
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662247-6
    ISSN 2075-4450
    ISSN 2075-4450
    DOI 10.3390/insects14100806
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  4. Article ; Online: Absolute monocyte count as a prognostic parameter in diffuse large B cell lymphoma.

    Irigoín, Victoria / Oliver, Carolina / López, Stefanía / Landoni, Ana Inés / Gabús, Raúl / Díaz, Lilián

    Revista medica de Chile

    2020  Volume 147, Issue 12, Page(s) 1553–1560

    Abstract: Background Prognosis of patients with Diffuse Large B Cell Lymphoma (DLBCL) is highly variable, and despite the use of modern immunochemotherapy regimens, almost 50% of patients will eventually relapse. Standard risk models, like the International ... ...

    Abstract Background Prognosis of patients with Diffuse Large B Cell Lymphoma (DLBCL) is highly variable, and despite the use of modern immunochemotherapy regimens, almost 50% of patients will eventually relapse. Standard risk models, like the International Prognostic Index or the Revised International Prognostic Index (R_IPI) incorporate patient and tumor characteristics but do not consider variables related to host adaptive immunity which have been shown to be of significant prognostic value in non-Hodgkin lymphomas. Aim To analyze the prognostic significance of the absolute monocyte count at diagnosis in diffuse large-B-cell lymphoma in a retrospective setting. Material and Methods We reviewed data of 171 patients with DLBCL treated with Rituximab-based immunochemotherapy at two reference public Hospitals in Montevideo-Uruguay. The outcome measures were overall and relapse free survival. Results The absolute monocyte count, analyzed as a dichotomized variable predicted progression-free and overall survival in low risk patients according to the R-IPI score. Worse outcomes were observed in those with high monocyte count al diagnosis. Conclusions Absolute monocyte count could help in the identification of high-risk patients otherwise expected to have a good prognosis according to traditional scores.
    MeSH term(s) Adolescent ; Adult ; Aged ; Aged, 80 and over ; Antineoplastic Combined Chemotherapy Protocols ; Female ; Humans ; Immunotherapy ; Leukocyte Count ; Lymphoma, Large B-Cell, Diffuse/blood ; Lymphoma, Large B-Cell, Diffuse/drug therapy ; Male ; Middle Aged ; Monocytes ; Prognosis ; Retrospective Studies ; Young Adult
    Language English
    Publishing date 2020-03-18
    Publishing country Chile
    Document type Journal Article
    ZDB-ID 732136-3
    ISSN 0717-6163 ; 0034-9887
    ISSN (online) 0717-6163
    ISSN 0034-9887
    DOI 10.4067/S0034-98872019001201553
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    In stock of ZB MED Cologne/Königswinter

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  5. Article ; Conference proceedings: Double endoscope technique for EUS-guided gastroenteroanastomosis using lumen-apposing metal stents (LAMS) in clinical practice

    Sanchez-Yague, A. / Rivera-Irigoin, R. / Canoniga, A. Gonzalez / Muñoz, C. Lopez / Perez-Aisa, A.

    Endoscopy

    2023  Volume 55, Issue S 02

    Event/congress ESGE Days 2023, Dublin, Ireland, 2023-04-20
    Language English
    Publishing date 2023-04-01
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article ; Conference proceedings
    ZDB-ID 80120-3
    ISSN 1438-8812 ; 0013-726X
    ISSN (online) 1438-8812
    ISSN 0013-726X
    DOI 10.1055/s-0043-1765989
    Database Thieme publisher's database

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  6. Article ; Online: Generation and characterization of Ccdc28b mutant mice links the Bardet-Biedl associated gene with mild social behavioral phenotypes.

    Fabregat, Matías / Niño-Rivero, Sofía / Pose, Sabrina / Cárdenas-Rodríguez, Magdalena / Bresque, Mariana / Hernández, Karina / Prieto-Echagüe, Victoria / Schlapp, Geraldine / Crispo, Martina / Lagos, Patricia / Lago, Natalia / Escande, Carlos / Irigoín, Florencia / Badano, Jose L

    PLoS genetics

    2022  Volume 18, Issue 6, Page(s) e1009896

    Abstract: CCDC28B (coiled-coil domain-containing protein 28B) was identified as a modifier in the ciliopathy Bardet-Biedl syndrome (BBS). Our previous work in cells and zebrafish showed that CCDC28B plays a role regulating cilia length in a mechanism that is not ... ...

    Abstract CCDC28B (coiled-coil domain-containing protein 28B) was identified as a modifier in the ciliopathy Bardet-Biedl syndrome (BBS). Our previous work in cells and zebrafish showed that CCDC28B plays a role regulating cilia length in a mechanism that is not completely understood. Here we report the generation of a Ccdc28b mutant mouse using CRISPR/Cas9 (Ccdc28b mut). Depletion of CCDC28B resulted in a mild phenotype. Ccdc28b mut animals i) do not present clear structural cilia affectation, although we did observe mild defects in cilia density and cilia length in some tissues, ii) reproduce normally, and iii) do not develop retinal degeneration or obesity, two hallmark features of reported BBS murine models. In contrast, Ccdc28b mut mice did show clear social interaction defects as well as stereotypical behaviors. This finding is indeed relevant regarding CCDC28B as a modifier of BBS since behavioral phenotypes have been documented in BBS. Overall, this work reports a novel mouse model that will be key to continue evaluating genetic interactions in BBS, deciphering the contribution of CCDC28B to modulate the presentation of BBS phenotypes. In addition, our data underscores a novel link between CCDC28B and behavioral defects, providing a novel opportunity to further our understanding of the genetic, cellular, and molecular basis of these complex phenotypes.
    MeSH term(s) Animals ; Bardet-Biedl Syndrome/genetics ; Bardet-Biedl Syndrome/metabolism ; Cilia/metabolism ; Mice ; Phenotype ; Retinal Degeneration/genetics ; Zebrafish/genetics
    Language English
    Publishing date 2022-06-02
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2186725-2
    ISSN 1553-7404 ; 1553-7390
    ISSN (online) 1553-7404
    ISSN 1553-7390
    DOI 10.1371/journal.pgen.1009896
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  7. Article ; Online: Pericarditis bacteriana por Cardiobacterium hominis: un caso clínico inusual.

    Salinas, José / Irígoin, Ailyn / Calvo, Mario / Concha, Carla / Ardiles, Leopoldo

    Revista chilena de infectologia : organo oficial de la Sociedad Chilena de Infectologia

    2016  Volume 33, Issue 6, Page(s) 691–695

    Abstract: The case of a male patient under hemodialytic therapy, who developed right heart failure is presented. Echocardiography revealed pericardial effusion, constrictive pattem in the right cavities, septation, without valvular damage and preserved systolic ... ...

    Title translation Cardiobacterium hominis pericarditis: an unusual case.
    Abstract The case of a male patient under hemodialytic therapy, who developed right heart failure is presented. Echocardiography revealed pericardial effusion, constrictive pattem in the right cavities, septation, without valvular damage and preserved systolic and diastolic function. Pericardial drainage and extensive pericardiectomy was performed obtaining cultures of pericardial tissue positive for an HACEK group organism, Cardiobacterium hominis, with repeatedly negative blood cultures. This is a rare clinical presentation of isolated bacterial pericarditis by an atypical microorganism, without associated endocarditis. The infection mechanisms are presented and the scarce available scientific literature is discussed in this study.
    MeSH term(s) Adult ; Cardiobacterium/isolation & purification ; Endocarditis, Bacterial/diagnosis ; Gram-Negative Bacterial Infections/diagnosis ; Humans ; Male
    Language Spanish
    Publishing date 2016-12
    Publishing country Chile
    Document type Case Reports ; Journal Article
    ZDB-ID 2048815-4
    ISSN 0717-6341 ; 0716-1018
    ISSN (online) 0717-6341
    ISSN 0716-1018
    DOI 10.4067/S0716-10182016000600013
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  8. Article: Clonal dissemination of Acinetobacter radioresistens among Humboldt penguins (Spheniscus humboldti) inhabiting a barren northern Peruvian island.

    Roca, Ignasi / Espinoza, Kathya / Irigoin-Lovera, Cinthia / Piquet, Maria / Palomino-Kobayashi, Luciano A / Castillo, Angie K / Gonzales-DelCarpio, Diego D / Viñes, Joaquim / Muñoz, Laura / Ymaña, Barbara / Oporto, Rosario / Zavalaga, Carlos / Pons, Maria J / Ruiz, Joaquim

    European journal of microbiology & immunology

    2024  

    Abstract: Acinetobacter spp. are often isolated from natural sources, but knowledge about their presence in wild animals is fragmented and uncomplete. The present study aimed to characterize a series of Acinetobacter radioresistens isolated from Humboldt penguins ( ...

    Abstract Acinetobacter spp. are often isolated from natural sources, but knowledge about their presence in wild animals is fragmented and uncomplete. The present study aimed to characterize a series of Acinetobacter radioresistens isolated from Humboldt penguins (Spheniscus humboldti). Fifteen Humboldt penguins from an inhabited northern Peruvian island were sampled. Microorganisms were identified by MALDI-TOF MS. Antibiotic susceptibility to 12 antimicrobial agents was established, and clonal relationships were determined. A representative isolate was selected for whole genome sequencing (WGS). A. radioresistens were isolated from the feces of 12 (80%) Humboldt penguins, being susceptible to all the antimicrobial agents tested, except eight cefotaxime-intermediate isolates. All A. radioresistens were clonally related. WGS showed that the isolate belonged to ST1972, the presence of two chromosomal encoded carbapenemases (blaOXA-23 and a putative subclass B3 metallo-β-lactamase), and a series of point mutations in antibiotic-resistance related chromosomal genes, which were considered as polymorphisms. In addition, a few virulence factors, including a capsule-encoding operon, superoxide dismutases, catalases, phospholipases and a siderophore receptor were identified. The present results suggest that A. radioresistens may be a common member of the gut microbiota of Humboldt penguins, but further studies in other geographical areas are needed to establish this finding.
    Language English
    Publishing date 2024-03-14
    Publishing country Hungary
    Document type Journal Article
    ZDB-ID 2652327-9
    ISSN 2062-8633 ; 2062-509X
    ISSN (online) 2062-8633
    ISSN 2062-509X
    DOI 10.1556/1886.2023.00066
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  9. Article ; Online: Real-world experience in older patients with diffuse large B-cell lymphoma treated in Latin America: A study by the Latin American study group of lymphoproliferative disorders (GELL).

    Candelaria, Myrna / Villela, Luis / Torres-Viera, Maria-Alejandra / Peña, Camila / Roa, Macarena / Zambrano, Daniela / Colunga-Pedraza, Perla R R / Robles-Rodríguez, Arianna / Pérez-Jacobo, Fernando / Oliver, Ana Carolina / Irigoín, Maria Victoria / Baena, Rosio / Idrobo, Henry / Paredes, Sally R / Oliday, Rosa / Castro, Denisse / Montaño-Figueroa, Efeen / Perini, Guillherme F / Fernández-Aguila, Julio D /
    Malpica, Luis E / Beltran, Brady E / Castillo, Jorge J

    Journal of geriatric oncology

    2023  Volume 14, Issue 7, Page(s) 101565

    MeSH term(s) Humans ; Aged ; Latin America/epidemiology ; Lymphoma, Large B-Cell, Diffuse/therapy ; Lymphoproliferative Disorders/therapy
    Language English
    Publishing date 2023-07-05
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2556813-9
    ISSN 1879-4076 ; 1879-4068
    ISSN (online) 1879-4076
    ISSN 1879-4068
    DOI 10.1016/j.jgo.2023.101565
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  10. Article ; Online: Correction: Follow-Up, Safety, and Satisfaction with Tele-bariatric Follow-Up Implemented During the COVID-19 French Lockdown: a 2-Year Follow-Up Study.

    Daouadji-Ghazouani, Ahmed / Aron-Wisnewsky, Judith / Torcivia, Adriana / Irigoin-Guichandut, Marc / Poitou, Christine / Faucher, Pauline / Ciangura, Cécile / Lassen, Pierre Bel / Clément, Karine / Vaillant, Jean-Christophe / Oppert, Jean-Michel / Genser, Laurent

    Obesity surgery

    2023  Volume 33, Issue 6, Page(s) 1958–1959

    Language English
    Publishing date 2023-04-26
    Publishing country United States
    Document type Published Erratum
    ZDB-ID 1070827-3
    ISSN 1708-0428 ; 0960-8923
    ISSN (online) 1708-0428
    ISSN 0960-8923
    DOI 10.1007/s11695-023-06612-4
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