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  1. Article ; Online: Streptococcus pseudoporcinus

    Papapanagiotou, Michalis / Ioannou, Petros / Alexakis, Konstantinos / Maraki, Sofia / Papadokostaki, Eleni / Kofteridis, Diamantis P

    Le infezioni in medicina

    2023  Volume 31, Issue 3, Page(s) 399–403

    Abstract: Streptococcus ... ...

    Abstract Streptococcus pseudoporcinus
    Language English
    Publishing date 2023-09-01
    Publishing country Italy
    Document type Case Reports
    ZDB-ID 2041081-5
    ISSN 2532-8689 ; 1124-9390
    ISSN (online) 2532-8689
    ISSN 1124-9390
    DOI 10.53854/liim-3103-14
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Euglycemic Diabetic Ketoacidosis Secondary to Dapagliflozin in a Patient with Colon Malignancy.

    Papadokostaki, Eleni / Liberopoulos, Evangelos

    Case reports in endocrinology

    2019  Volume 2019, Page(s) 3901741

    Abstract: The use of sodium-glucose cotransporter 2 (SGLT2) inhibitors for the treatment of type 2 diabetes is steadily increasing. SGLT2 inhibitors are associated with weight loss, lowering of blood pressure, and low hypoglycemia risk along with beneficial ... ...

    Abstract The use of sodium-glucose cotransporter 2 (SGLT2) inhibitors for the treatment of type 2 diabetes is steadily increasing. SGLT2 inhibitors are associated with weight loss, lowering of blood pressure, and low hypoglycemia risk along with beneficial cardiovascular and renoprotective effects. In view of the increasing use of SGLT2i, physicians must be aware of their adverse effects. Euglycemic diabetic ketoacidosis (euDKA) is a well-recognized adverse effect of SGLT2i. We present here a case of euglycemic diabetic ketoacidosis secondary to dapagliflozin use in a type 2 diabetic patient with colon cancer. To the best of our knowledge, this is first report of SGLT2 inhibitor-associated euDKA in a patient with underlying colon cancer.
    Language English
    Publishing date 2019-05-06
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2627633-1
    ISSN 2090-651X ; 2090-6501
    ISSN (online) 2090-651X
    ISSN 2090-6501
    DOI 10.1155/2019/3901741
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: COVID-19 and diabetes: What does the clinician need to know?

    Papadokostaki, Eleni / Tentolouris, Nikolaos / Liberopoulos, Evangelos

    Primary care diabetes

    2020  Volume 14, Issue 5, Page(s) 558–563

    Abstract: COVID-19 and diabetes are currently two global pandemics. Epidemiological studies indicate that diabetes is the second most common comorbidity in COVID-19. This review aims to summarize currently available data about prevalence, possible ... ...

    Abstract COVID-19 and diabetes are currently two global pandemics. Epidemiological studies indicate that diabetes is the second most common comorbidity in COVID-19. This review aims to summarize currently available data about prevalence, possible pathophysiological mechanisms and management of patients with diabetes and COVID-19.
    MeSH term(s) Betacoronavirus ; Blood Glucose/metabolism ; COVID-19 ; Comorbidity ; Coronavirus Infections/epidemiology ; Diabetes Mellitus/blood ; Diabetes Mellitus/epidemiology ; Global Health ; Humans ; Pandemics ; Pneumonia, Viral/epidemiology ; Practice Patterns, Physicians' ; Prevalence ; Risk Factors ; SARS-CoV-2
    Chemical Substances Blood Glucose
    Keywords covid19
    Language English
    Publishing date 2020-07-03
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2273997-X
    ISSN 1878-0210 ; 1751-9918
    ISSN (online) 1878-0210
    ISSN 1751-9918
    DOI 10.1016/j.pcd.2020.06.010
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Hydropneumothorax as a complication of necrotizing pneumonia.

    Papazachariou, Andria / Papadokostaki, Eleni / Kypraiou, Despoina / Malikides, Vironas / Papakitsou, Ioanna / Filippatos, Theodosios D / Ioannou, Petros / Kofteridis, Diamantis P

    Germs

    2023  Volume 13, Issue 4, Page(s) 332–337

    Abstract: Introduction: Hydropneumothorax with a bronchopleural fistula is an infrequent but severe complication of necrotizing pneumonia associated with high morbidity and mortality. Few cases in the adult population have been reported.: Case report: This is ... ...

    Abstract Introduction: Hydropneumothorax with a bronchopleural fistula is an infrequent but severe complication of necrotizing pneumonia associated with high morbidity and mortality. Few cases in the adult population have been reported.
    Case report: This is a case of a 76-year-old male patient who developed pneumonia caused by
    Conclusions: Early recognition and appropriate management of pneumonia complications, such as hydropneumothorax, including thoracic surgeon interventions, are crucial as this complication can be fatal. Factors like the patient's overall status, preferences, and comorbidities may have a crucial effect on clinical decisions and outcomes.
    Language English
    Publishing date 2023-12-31
    Publishing country Romania
    Document type Case Reports
    ZDB-ID 2649305-6
    ISSN 2248-2997
    ISSN 2248-2997
    DOI 10.18683/germs.2023.1402
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: COVID-19 and diabetes

    Papadokostaki, Eleni / Tentolouris, Nikolaos / Liberopoulos, Evangelos

    Primary Care Diabetes

    What does the clinician need to know?

    2020  Volume 14, Issue 5, Page(s) 558–563

    Keywords Internal Medicine ; Nutrition and Dietetics ; Endocrinology, Diabetes and Metabolism ; covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    ZDB-ID 2273997-X
    ISSN 1878-0210 ; 1751-9918
    ISSN (online) 1878-0210
    ISSN 1751-9918
    DOI 10.1016/j.pcd.2020.06.010
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article: COVID-19 and diabetes: What does the clinician need to know?

    Papadokostaki, Eleni / Tentolouris, Nikolaos / Liberopoulos, Evangelos

    Prim Care Diabetes

    Abstract: COVID-19 and diabetes are currently two global pandemics. Epidemiological studies indicate that diabetes is the second most common comorbidity in COVID-19. This review aims to summarize currently available data about prevalence, possible ... ...

    Abstract COVID-19 and diabetes are currently two global pandemics. Epidemiological studies indicate that diabetes is the second most common comorbidity in COVID-19. This review aims to summarize currently available data about prevalence, possible pathophysiological mechanisms and management of patients with diabetes and COVID-19.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #623032
    Database COVID19

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  7. Article: Immunogenicity of SARS-CoV-2 BNT162b2 Vaccine in People with Diabetes: A Prospective Observational Study.

    Papadokostaki, Eleni / Tentolouris, Anastasios / Anastasiou, Ioanna A / Psichogiou, Mina / Iliaki, Evangelia / Eleftheriadou, Ioanna / Hatzakis, Angelos / Tentolouris, Nikolaos

    Vaccines

    2022  Volume 10, Issue 3

    Abstract: The mRNA-based BNT162b2 vaccine has demonstrated high efficacy against severe SARS-CoV-2. However, data regarding immune response in people with diabetes mellitus (DM) after vaccination with the BNT162b2 vaccine are limited. In this prospective ... ...

    Abstract The mRNA-based BNT162b2 vaccine has demonstrated high efficacy against severe SARS-CoV-2. However, data regarding immune response in people with diabetes mellitus (DM) after vaccination with the BNT162b2 vaccine are limited. In this prospective observational study, we examined humoral immune response in participants with and without DM after vaccination with the BNT162b2 mRNA vaccine. A total of 174 participants (58 with and 116 without diabetes, matched for age) were included. Antibodies were measured 21 days after the first dose, 7−15 days after the second dose, and 70−75 days after the second and before the third dose of the vaccine. Antibodies were measured by an anti-SARS-CoV-2 receptor-binding domain IgG (Abs-RBD-IgG) assay by a chemiluminescent microparticle immune assay; values > 50 AU/mL are considered protective from severe disease. Almost 17% of participants with DM did not develop adequate humoral immune response to the BNT162b2 mRNA vaccine after the first dose; however, it was high and similar after the second dose in both participants with and without DM and remained so almost 2 months after the second dose of the vaccine. Geometric mean values of Abs-RBD-IgG were not significantly different between participants with and without DM during the study. At least two doses of the BNT162b2 vaccine are necessary to ensure adequate and sustainable immune response in people with DM.
    Language English
    Publishing date 2022-03-02
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2703319-3
    ISSN 2076-393X
    ISSN 2076-393X
    DOI 10.3390/vaccines10030382
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Canagliflozin and Amputation Risk: Evidence So Far.

    Papadokostaki, Eleni / Rizos, Evangelos / Tigas, Stelios / Liberopoulos, Evangelos N

    The international journal of lower extremity wounds

    2019  Volume 19, Issue 1, Page(s) 21–26

    Abstract: The CANVAS program detected a 2-fold increased risk of lower limb amputation in patients treated with canagliflozin compared with those with placebo. This adverse effect was not confirmed in the CREDENCE trial. Moreover, randomized controlled trials with ...

    Abstract The CANVAS program detected a 2-fold increased risk of lower limb amputation in patients treated with canagliflozin compared with those with placebo. This adverse effect was not confirmed in the CREDENCE trial. Moreover, randomized controlled trials with other agents in this class, dapagliflozin and empagliflozin, did not detect increased risk of amputation. Observational studies, cohort studies, and pharmacovigilance reports with sodium-glucose cotransporter 2 inhibitor (SGLT2i) have reported conflicting results. Whether this adverse event is a drug effect specific to canagliflozin, or a SGLT2i class effect, remains controversial. Until more evidence emerges, clinicians should avoid using SGLT2i, especially canagliflozin, in patients with previous amputations or existing foot ulceration.
    MeSH term(s) Amputation/methods ; Canagliflozin/pharmacology ; Diabetes Mellitus, Type 2/complications ; Diabetes Mellitus, Type 2/drug therapy ; Diabetic Foot/etiology ; Diabetic Foot/surgery ; Humans ; Pharmacovigilance ; Randomized Controlled Trials as Topic ; Sodium-Glucose Transporter 2 Inhibitors/pharmacology
    Chemical Substances Sodium-Glucose Transporter 2 Inhibitors ; Canagliflozin (0SAC974Z85)
    Language English
    Publishing date 2019-11-08
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2171119-7
    ISSN 1552-6941 ; 1534-7346
    ISSN (online) 1552-6941
    ISSN 1534-7346
    DOI 10.1177/1534734619878090
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Immunogenicity of SARS-CoV-2 BNT162b2 Vaccine in People with Diabetes

    Eleni Papadokostaki / Anastasios Tentolouris / Ioanna A. Anastasiou / Mina Psichogiou / Evangelia Iliaki / Ioanna Eleftheriadou / Angelos Hatzakis / Nikolaos Tentolouris

    Vaccines, Vol 10, Iss 382, p

    A Prospective Observational Study

    2022  Volume 382

    Abstract: The mRNA-based BNT162b2 vaccine has demonstrated high efficacy against severe SARS-CoV-2. However, data regarding immune response in people with diabetes mellitus (DM) after vaccination with the BNT162b2 vaccine are limited. In this prospective ... ...

    Abstract The mRNA-based BNT162b2 vaccine has demonstrated high efficacy against severe SARS-CoV-2. However, data regarding immune response in people with diabetes mellitus (DM) after vaccination with the BNT162b2 vaccine are limited. In this prospective observational study, we examined humoral immune response in participants with and without DM after vaccination with the BNT162b2 mRNA vaccine. A total of 174 participants (58 with and 116 without diabetes, matched for age) were included. Antibodies were measured 21 days after the first dose, 7–15 days after the second dose, and 70–75 days after the second and before the third dose of the vaccine. Antibodies were measured by an anti-SARS-CoV-2 receptor-binding domain IgG (Abs-RBD-IgG) assay by a chemiluminescent microparticle immune assay; values > 50 AU/mL are considered protective from severe disease. Almost 17% of participants with DM did not develop adequate humoral immune response to the BNT162b2 mRNA vaccine after the first dose; however, it was high and similar after the second dose in both participants with and without DM and remained so almost 2 months after the second dose of the vaccine. Geometric mean values of Abs-RBD-IgG were not significantly different between participants with and without DM during the study. At least two doses of the BNT162b2 vaccine are necessary to ensure adequate and sustainable immune response in people with DM.
    Keywords humoral immune response ; SARS-CoV-2 ; COVID-19 ; vaccine ; antibodies ; Medicine ; R
    Subject code 616
    Language English
    Publishing date 2022-03-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article: Preparation and investigation of distinct and shape stable paraffin/SiO2 composite PCM nanospheres

    Belessiotis, George V / Papadokostaki, Kyriaki G / Favvas, Evangelos P / Efthimiadou, Eleni K / Karellas, Sotirios

    Energy conversion and management. 2018 July 15, v. 168

    2018  

    Abstract: The synthesis of a shape stable paraffin/SiO2 composite PCM, for use in latent heat storage, comprised of distinct nanospheres, using a novel and simple chemically aided infiltration method was investigated and the produced samples were characterized. ... ...

    Abstract The synthesis of a shape stable paraffin/SiO2 composite PCM, for use in latent heat storage, comprised of distinct nanospheres, using a novel and simple chemically aided infiltration method was investigated and the produced samples were characterized. SiO2 spheres were synthesized, with the sol-gel method, and then used to encapsulate paraffin wax using several different preparation ratios of paraffin to SiO2. Τhe samples’ constitution and morphology were characterized by FT-IR spectroscopy and scanning electron microscopy (SEM) respectively. Thermogravimetric analysis (TGA) was used for the paraffin mass percentage determination. The results were indicative of paraffin encapsulation inside the porous network of the SiO2 spheres. DSC was used to investigate the thermophysical properties of the composite samples and for their evaluation as PCMs. The sample with the highest encapsulation ratio (B4 at 78.15%) had a paraffin mass percentage of 80% and a latent heat of ∼ 156 J/g. The encapsulation’s influence on paraffin’s thermal properties was investigated and an optimum preparation ratio was determined. The composite nanoparticles retained a large amount of the paraffin’s latent heat while showing no signs of aggregation -a novelty for paraffin/SiO2 nanoPCM- and presenting enhancements that make them promising materials for heat storage applications (LHTES).
    Keywords Fourier transform infrared spectroscopy ; encapsulation ; heat ; latent heat ; nanoparticles ; nanospheres ; paraffin wax ; scanning electron microscopy ; silica ; sol-gel processing ; thermogravimetry
    Language English
    Dates of publication 2018-0715
    Size p. 382-394.
    Publishing place Elsevier Ltd
    Document type Article
    ZDB-ID 2000891-0
    ISSN 0196-8904
    ISSN 0196-8904
    DOI 10.1016/j.enconman.2018.04.059
    Database NAL-Catalogue (AGRICOLA)

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