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  1. Article ; Online: Maximizing HIV Organ Policy Equity for transplant candidates with HIV.

    Boyarsky, Brian J / Durand, Christine M / Stock, Peter G

    Transplant infectious disease : an official journal of the Transplantation Society

    2022  , Page(s) e13911

    Language English
    Publishing date 2022-07-23
    Publishing country Denmark
    Document type Editorial
    ZDB-ID 1476094-0
    ISSN 1399-3062 ; 1398-2273
    ISSN (online) 1399-3062
    ISSN 1398-2273
    DOI 10.1111/tid.13911
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    Zs.A 5100: Show issues Location:
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  2. Article ; Online: The higher impact of the COVID-19 pandemic on resident/fellow training in low- and middle-income countries.

    Sandal, Shaifali / Boyarsky, Brian J / Cantarovich, Marcelo

    Transplant international : official journal of the European Society for Organ Transplantation

    2021  Volume 34, Issue 5, Page(s) 988–989

    MeSH term(s) COVID-19 ; Developing Countries ; Humans ; Pandemics ; SARS-CoV-2
    Language English
    Publishing date 2021-03-16
    Publishing country Switzerland
    Document type Letter
    ZDB-ID 639435-8
    ISSN 1432-2277 ; 0934-0874
    ISSN (online) 1432-2277
    ISSN 0934-0874
    DOI 10.1111/tri.13853
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    Zs.A 2358: Show issues Location:
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  3. Article ; Online: Response to "The real number of organs from uncontrolled donation after circulatory determination of death donors".

    Boyarsky, Brian J / Segev, Dorry L / Ottmann, Shane E

    American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

    2021  Volume 21, Issue 6, Page(s) 2303

    MeSH term(s) Death ; Humans ; Tissue Donors ; Tissue and Organ Procurement ; United States
    Language English
    Publishing date 2021-03-04
    Publishing country United States
    Document type Letter ; Research Support, N.I.H., Extramural ; Comment
    ZDB-ID 2060594-8
    ISSN 1600-6143 ; 1600-6135
    ISSN (online) 1600-6143
    ISSN 1600-6135
    DOI 10.1111/ajt.16526
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    Zs.A 5542: Show issues Location:
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  4. Article ; Online: Transplanting Organs from Donors with HIV or Hepatitis C: The Viral Frontier.

    Boyarsky, Brian J / Strauss, Alexandra T / Segev, Dorry L

    World journal of surgery

    2021  Volume 45, Issue 12, Page(s) 3503–3510

    Abstract: A wide gap between the increasing demand for organs and the limited supply leads to immeasurable loss of life each year. The organ shortage could be attenuated by donors with human immunodeficiency virus (HIV) or hepatitis C virus (HCV). The ... ...

    Abstract A wide gap between the increasing demand for organs and the limited supply leads to immeasurable loss of life each year. The organ shortage could be attenuated by donors with human immunodeficiency virus (HIV) or hepatitis C virus (HCV). The transplantation of organs from HIV+ deceased donors into HIV+ individuals (HIV D+ /R+) was initiated in South Africa in 2010; however, this practice was forbidden in the USA until the HIV Organ Policy Equity (HOPE) Act in 2013. HIV D+/R+ transplantation is now practiced in the USA as part of ongoing research studies, helping to reduce waiting times for all patients on the waitlist. The introduction of direct acting antivirals for HCV has revolutionized the utilization of donors with HCV for HCV-uninfected (HCV-) recipients. This is particularly relevant as the HCV donor pool has increased substantially in the context of the rise in deaths related to drug overdose from injection drug use. This article serves to review the current literature on using organs from donors with HIV or HCV.
    MeSH term(s) Antiviral Agents/therapeutic use ; HIV Infections/drug therapy ; Hepacivirus ; Hepatitis C/complications ; Hepatitis C, Chronic/drug therapy ; Humans ; Tissue Donors
    Chemical Substances Antiviral Agents
    Language English
    Publishing date 2021-01-20
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 224043-9
    ISSN 1432-2323 ; 0364-2313
    ISSN (online) 1432-2323
    ISSN 0364-2313
    DOI 10.1007/s00268-020-05924-1
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    Zs.A 1336: Show issues Location:
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  5. Article ; Online: From Bench to Bill: How a Transplant Nuance Became 1 of Only 57 Laws Passed in 2013.

    Boyarsky, Brian J / Segev, Dorry L

    Annals of surgery

    2016  Volume 263, Issue 3, Page(s) 430–433

    MeSH term(s) HIV Seropositivity ; Health Policy/economics ; Health Policy/legislation & jurisprudence ; Humans ; Kidney Transplantation/economics ; Kidney Transplantation/legislation & jurisprudence ; Medicare/economics ; Medicare/legislation & jurisprudence ; Periodicals as Topic ; United States
    Language English
    Publishing date 2016-03
    Publishing country United States
    Document type Journal Article
    ZDB-ID 340-2
    ISSN 1528-1140 ; 0003-4932
    ISSN (online) 1528-1140
    ISSN 0003-4932
    DOI 10.1097/SLA.0000000000001352
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  6. Article ; Online: Improving OPO performance through national data availability.

    Doby, Brianna L / Boyarsky, Brian J / Gentry, Sommer / Segev, Dorry L

    American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

    2019  Volume 19, Issue 10, Page(s) 2675–2677

    MeSH term(s) Death ; Humans ; Tissue and Organ Procurement
    Language English
    Publishing date 2019-07-17
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 2060594-8
    ISSN 1600-6143 ; 1600-6135
    ISSN (online) 1600-6143
    ISSN 1600-6135
    DOI 10.1111/ajt.15508
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    Zs.A 5542: Show issues Location:
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  7. Article ; Online: Immunosuppression practices during the COVID-19 pandemic: A multinational survey study of transplant programs.

    Sandal, Shaifali / Boyarsky, Brian J / Massie, Allan / Chiang, Teresa Po-Yu / Segev, Dorry L / Cantarovich, Marcelo

    Clinical transplantation

    2021  Volume 35, Issue 8, Page(s) e14376

    Abstract: During the COVID-19 pandemic, there has been wide heterogeneity in the medical management of transplant recipients. We aimed to pragmatically capture immunosuppression practices globally following the early months of the pandemic. From June to September ... ...

    Abstract During the COVID-19 pandemic, there has been wide heterogeneity in the medical management of transplant recipients. We aimed to pragmatically capture immunosuppression practices globally following the early months of the pandemic. From June to September 2020, we surveyed 1267 physicians; 40.5% from 71 countries participated. Management decisions were made on a case-by-case basis by the majority (69.6%) of the programs. Overall, 76.8% performed ≥1 transplantation and many commented on avoiding high-risk transplantations. For induction, 26.5% were less likely to give T-cell depletion and 14.8% were more likely to give non-depleting agents. These practices varied by program-level factors more so than the COVID-19 burden. In patients with mild, moderate and severe COVID-19 symptoms 59.7%, 76.0%, and 79.5% decreased/stopped anti-metabolites, 23.2%, 45.4%, and 68.2% decreased/stopped calcineurin inhibitors, and 25.7%, 43.9%, and 57.7% decreased/stopped mTOR inhibitors, respectively. Also, 2.1%, 30.6%, and 46.0% increased steroids in patients with mild, moderate, and severe COVID-19 symptoms. For prevalent transplant recipients, some programs also reported decreasing/stopping steroids (1.8%), anti-metabolites (10.3%), calcineurin inhibitors (4.1%), and mTOR inhibitors (5.5%). Transplant programs changed immunosuppression practices but also avoided high-risk transplants and increased maintenance steroids. The long-term ramifications of these practices remain to be seen as programs face the aftermath of the pandemic.
    MeSH term(s) COVID-19 ; Humans ; Immunosuppression Therapy ; Immunosuppressive Agents/therapeutic use ; Kidney Transplantation ; Pandemics ; SARS-CoV-2 ; Transplant Recipients
    Chemical Substances Immunosuppressive Agents
    Language English
    Publishing date 2021-06-13
    Publishing country Denmark
    Document type Journal Article
    ZDB-ID 639001-8
    ISSN 1399-0012 ; 0902-0063
    ISSN (online) 1399-0012
    ISSN 0902-0063
    DOI 10.1111/ctr.14376
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    Zs.A 2204: Show issues Location:
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  8. Article ; Online: Safety and Immunogenicity of a Third Dose of SARS-CoV-2 Vaccine in Solid Organ Transplant Recipients: A Case Series.

    Werbel, William A / Boyarsky, Brian J / Ou, Michael T / Massie, Allan B / Tobian, Aaron A R / Garonzik-Wang, Jacqueline M / Segev, Dorry L

    Annals of internal medicine

    2021  Volume 174, Issue 9, Page(s) 1330–1332

    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; Antibodies, Viral/blood ; COVID-19/prevention & control ; COVID-19 Vaccines/adverse effects ; COVID-19 Vaccines/immunology ; Female ; Humans ; Immunocompromised Host ; Male ; Middle Aged ; SARS-CoV-2/immunology ; Transplant Recipients
    Chemical Substances Antibodies, Viral ; COVID-19 Vaccines
    Language English
    Publishing date 2021-06-15
    Publishing country United States
    Document type Letter
    ZDB-ID 336-0
    ISSN 1539-3704 ; 0003-4819
    ISSN (online) 1539-3704
    ISSN 0003-4819
    DOI 10.7326/L21-0282
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  9. Article ; Online: Antibody durability 6 months after two doses of SARS-CoV-2 mRNA vaccines in patients with rheumatic and musculoskeletal disease.

    Frey, Sarah / Chiang, Teresa Po-Yu / Connolly, Caoilfhionn M / Teles, Mayan / Alejo, Jennifer L / Boyarsky, Brian J / Christopher-Stine, Lisa / Werbel, William A / Massie, Allan B / Segev, Dorry L / Paik, Julie J

    The Lancet. Rheumatology

    2022  Volume 4, Issue 4, Page(s) e241–e243

    Language English
    Publishing date 2022-01-18
    Publishing country England
    Document type Journal Article
    ISSN 2665-9913
    ISSN (online) 2665-9913
    DOI 10.1016/S2665-9913(21)00417-3
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  10. Article ; Online: Antibody Response to the Janssen COVID-19 Vaccine in Solid Organ Transplant Recipients.

    Boyarsky, Brian J / Chiang, Teresa P-Y / Ou, Michael T / Werbel, William A / Massie, Allan B / Segev, Dorry L / Garonzik-Wang, Jacqueline M

    Transplantation

    2021  Volume 105, Issue 8, Page(s) e82–e83

    MeSH term(s) Ad26COVS1 ; Antibodies, Viral/blood ; Biomarkers/blood ; COVID-19/immunology ; COVID-19/prevention & control ; COVID-19/virology ; COVID-19 Vaccines/administration & dosage ; Humans ; Immunity, Humoral ; Immunogenicity, Vaccine ; Organ Transplantation ; SARS-CoV-2/immunology ; Spike Glycoprotein, Coronavirus/immunology ; Vaccination
    Chemical Substances Ad26COVS1 (JT2NS6183B) ; Antibodies, Viral ; Biomarkers ; COVID-19 Vaccines ; Spike Glycoprotein, Coronavirus ; spike protein, SARS-CoV-2
    Language English
    Publishing date 2021-06-05
    Publishing country United States
    Document type Comparative Study ; Letter ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 208424-7
    ISSN 1534-6080 ; 0041-1337
    ISSN (online) 1534-6080
    ISSN 0041-1337
    DOI 10.1097/TP.0000000000003850
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