LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 1701

Search options

  1. Article ; Online: Previously undescribed vitamin D C-3 epimer occurs in substantial amounts in the blood of cats.

    Sprinkle, Megan C / Hooper, Sarah E / Backus, Robert C

    Journal of feline medicine and surgery

    2017  Volume 20, Issue 2, Page(s) 83–90

    Abstract: ... a C-3, alpha-epimer of 25-hydroxycholecalciferol (3-epi-25(OH)D ... Objectives The aim of this report is to describe the identification of a novel vitamin D metabolite ...

    Abstract Objectives The aim of this report is to describe the identification of a novel vitamin D metabolite, a C-3, alpha-epimer of 25-hydroxycholecalciferol (3-epi-25(OH)D
    MeSH term(s) Animals ; Calcifediol/blood ; Cats/metabolism ; Chromatography, High Pressure Liquid ; Dogs/metabolism ; Male ; Rats/metabolism ; Vitamins/blood
    Chemical Substances Vitamins ; Calcifediol (P6YZ13C99Q)
    Language English
    Publishing date 2017-02-01
    Publishing country England
    Document type Comparative Study ; Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 2049047-1
    ISSN 1532-2750 ; 1098-612X
    ISSN (online) 1532-2750
    ISSN 1098-612X
    DOI 10.1177/1098612X17693523
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Article: Previously undescribed vitamin D C-3 epimer occurs in substantial amounts in the blood of cats

    Sprinkle, Megan C / Hooper, Sarah E / Backus, Robert C

    Journal of feline medicine and surgery. , v. 20, no. 2

    2018  

    Abstract: The aim of this report is to describe the identification of a novel vitamin D metabolite, a C-3 ... a conventional marker of vitamin D status. Serum 25(OH)D3 and 3-epi-25(OH)D3 concentrations were measured ... tandem mass spectrophotometry. Dietary intake and dietary concentrations of vitamin D were also measured ...

    Abstract The aim of this report is to describe the identification of a novel vitamin D metabolite, a C-3, alpha-epimer of 25-hydroxycholecalciferol (3-epi-25(OH)D3), in serum and plasma extracts of cat blood and compare its abundance in cat, dog and rat serum to 25-hydroxycholecalciferol (25(OH)D3), a conventional marker of vitamin D status. Serum 25(OH)D3 and 3-epi-25(OH)D3 concentrations were measured in healthy cohorts of cats (n = 8), dogs (n = 8) and rats (n = 17) using validated reverse and normal-phase high-performance liquid chromatography methods. The methods were verified using liquid chromatography tandem mass spectrophotometry. Dietary intake and dietary concentrations of vitamin D were also measured for evaluation of species differences and effect of dietary change on vitamin D metabolite concentrations. Differences between cat serum and plasma metabolite concentrations were determined. Detectable concentrations of 3-epi-25(OH)D3 were observed in all cats and rats. No 3-epi-25(OH)D3 was detected in dogs, where our limit of detection was 5 ng/ml. There were significant differences (P <0.05) in serum concentrations of 25(OH)D3 and 3-epi-25(OH)D3 among species, with cats having the greatest concentrations of both metabolites. Serum and plasma results were not significantly different. A diet change, which resulted in an increase in vitamin D intake among the cats, affected serum concentration with an increase (P = 0.004) in 3-epi-25(OH)D3 but no significant change in 25(OH)D3. Serum and plasma of cats contain 3-epi-25(OH)D3 in varied and extraordinary concentrations, much greater than in rats and certainly than that of dogs, a species for which the metabolite was not detected. Importantly, this finding indicates a C-3 epimerization pathway is quantitatively significant for vitamin D metabolism in domestic cats, making 3-epi-25(OH)D3 assays essential for the evaluation of vitamin D status in cats and positioning the cat as a novel model for study of this pathway.
    Keywords 25-hydroxycholecalciferol ; blood serum ; cats ; detection limit ; dogs ; food intake ; high performance liquid chromatography ; interspecific variation ; mass spectrometry ; metabolism ; metabolites ; models ; rats ; vitamin status
    Language English
    Dates of publication 2018-02
    Size p. 83-90.
    Publishing place SAGE Publications
    Document type Article
    ZDB-ID 2049047-1
    ISSN 1532-2750 ; 1098-612X
    ISSN (online) 1532-2750
    ISSN 1098-612X
    DOI 10.1177/1098612X17693523
    Database NAL-Catalogue (AGRICOLA)

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Article: Cross-jurisdictional transmission of Mycobacterium tuberculosis in Maryland and Washington, D C, 1996-2000, linked to the homeless.

    Lathan, Monica / Mukasa, Leonard Ntaate / Hooper, Nancy / Golub, Jonathan / Baruch, Nancy / Mulcahy, Donna / Benjamin, William / Cronin, Wendy A

    Emerging infectious diseases

    2002  Volume 8, Issue 11, Page(s) 1249–1251

    Abstract: From 1996 to 2000, 23 Maryland and Washington, D.C., tuberculosis cases were identified in one six ... to another member; half the patients were associated with a Washington, D.C., homeless shelter ...

    Abstract From 1996 to 2000, 23 Maryland and Washington, D.C., tuberculosis cases were identified in one six-band DNA cluster. Cases were clustered on the basis of their Mycobacterium tuberculosis isolates. Medical record reviews and interviews were conducted to identify epidemiologic linkages. Eighteen (78%) of the 23 case-patients with identical restriction fragment length polymorphism patterns were linked to another member; half the patients were associated with a Washington, D.C., homeless shelter. Molecular epidemiology defined the extent of this large, cross-jurisdictional outbreak.
    MeSH term(s) Adult ; Cluster Analysis ; Disease Outbreaks ; District of Columbia/epidemiology ; Female ; Genotype ; Homeless Persons ; Humans ; Male ; Maryland/epidemiology ; Middle Aged ; Molecular Epidemiology ; Mycobacterium tuberculosis/classification ; Mycobacterium tuberculosis/genetics ; Mycobacterium tuberculosis/isolation & purification ; Polymorphism, Restriction Fragment Length ; Risk Factors ; Time Factors ; Tuberculosis/epidemiology ; Tuberculosis/microbiology ; Tuberculosis/transmission
    Language English
    Publishing date 2002-11
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 1380686-5
    ISSN 1080-6040
    ISSN 1080-6040
    DOI 10.3201/eid0811.020245
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 4778: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article: Psammaplysenes C and D, cytotoxic alkaloids from Psammoclemma sp.

    Buchanan, Malcolm S / Carroll, Anthony R / Addepalli, Rama / Avery, Vicky M / Hooper, John N A / Quinn, Ronald J

    Journal of natural products

    2007  Volume 70, Issue 11, Page(s) 1827–1829

    Abstract: ... due to the cytotoxicity of two new bromotyrosine alkaloids, psammaplysenes C (1) and D (2), and not ...

    Abstract The sponge Psammoclemma sp. was investigated as part of our studies to discover P2X 7 receptor antagonists for the treatment of inflammatory disease. The biological activity of this extract was found to be due to the cytotoxicity of two new bromotyrosine alkaloids, psammaplysenes C (1) and D (2), and not P2X 7-specific activity. Their structures were determined by 1D and 2D NMR spectroscopy.
    MeSH term(s) Alkaloids/chemistry ; Alkaloids/isolation & purification ; Alkaloids/pharmacology ; Animals ; Australia ; Cytotoxins/chemistry ; Cytotoxins/isolation & purification ; Cytotoxins/pharmacology ; Drug Screening Assays, Antitumor ; Humans ; Molecular Structure ; Nuclear Magnetic Resonance, Biomolecular ; Porifera/chemistry ; Purinergic P2 Receptor Antagonists ; Receptors, Purinergic P2X7 ; Tyrosine/analogs & derivatives ; Tyrosine/chemistry ; Tyrosine/isolation & purification ; Tyrosine/pharmacology
    Chemical Substances Alkaloids ; Cytotoxins ; P2RX7 protein, human ; Purinergic P2 Receptor Antagonists ; Receptors, Purinergic P2X7 ; psammaplysene C ; psammaplysene D ; Tyrosine (42HK56048U)
    Language English
    Publishing date 2007-11
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 304325-3
    ISSN 1520-6025 ; 0163-3864
    ISSN (online) 1520-6025
    ISSN 0163-3864
    DOI 10.1021/np0703646
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1144: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Article ; Audio / Video: Psammaplysenes C and D, Cytotoxic Alkaloids from Psammoclemma sp

    Buchanan, M.S / Carroll, A.R / Addepalli, R / Avery, V.M / Hooper, J.N.A / Quinn, R.J

    Journal of natural products. 2007 Nov., v. 70, no. 11

    2007  

    Keywords Porifera ; tyrosine ; alkaloids ; chemical structure ; spectral analysis ; cytotoxicity ; Queensland
    Language English
    Dates of publication 2007-11
    Size p. 1827-1829.
    Document type Article ; Audio / Video
    ZDB-ID 304325-3
    ISSN 1520-6025 ; 0163-3864
    ISSN (online) 1520-6025
    ISSN 0163-3864
    DOI 10.1021/np0703646
    Database NAL-Catalogue (AGRICOLA)

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1144: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  6. Book ; Online ; E-Book: Perspectives in occupational therapy education

    Taff, Steven D. / Grajo, Lenin C. / Hooper, Barbara R.

    past, present, and future

    2020  

    Abstract: ... Lenin C. Grajo, and Barbara R. Hooper offer helpful tips, practical tools, and fresh insights to support ... international viewpoints on the development of the profession. With this mission in mind, Drs. Steven D. Taff ...

    Author's details Steven D. Taff, Lenin C. Grajo, Barbara R. Hooper
    Abstract Perspectives on Occupational Therapy Education: Past, Present, and Future outlines a path forward for occupational therapy educators, incorporating the impact of historical context, contemporary issues and trends, and international viewpoints on the development of the profession. With this mission in mind, Drs. Steven D. Taff, Lenin C. Grajo, and Barbara R. Hooper offer helpful tips, practical tools, and fresh insights to support current and future educators in developing their teaching philosophies and pedagogies.
    Keywords Occupational therapy-Study and teaching ; Electronic books
    Language English
    Size 1 Online-Ressource (xxv, 230 Seiten), Illustrationen, Diagramme
    Publisher SLACK Incorporated
    Publishing place Thorofare, NJ
    Publishing country United States
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT021286210
    ISBN 978-1-63091-549-0 ; 978-1-63091-548-3 ; 9781630915476 ; 1-63091-549-1 ; 1-63091-548-3 ; 1630915475
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

    Full text online

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  7. Article: Mycalamides C and D, cytotoxic compounds from the marine sponge Stylinos n. species.

    Simpson, J S / Garson, M J / Blunt, J W / Munro, M H / Hooper, J N

    Journal of natural products

    2000  Volume 63, Issue 5, Page(s) 704–706

    Abstract: The new cytotoxic compounds, mycalamides C (3) and D (4), have been isolated from the marine sponge ...

    Abstract The new cytotoxic compounds, mycalamides C (3) and D (4), have been isolated from the marine sponge Stylinos n. sp., along with the known theopederin E (1) and mycalamide A (2).
    MeSH term(s) Animals ; Antineoplastic Agents/isolation & purification ; Antineoplastic Agents/pharmacology ; Leukemia P388/drug therapy ; Magnetic Resonance Spectroscopy ; Optical Rotation ; Porifera/chemistry ; Pyrans/isolation & purification ; Pyrans/pharmacology ; Tumor Cells, Cultured
    Chemical Substances Antineoplastic Agents ; Pyrans ; mycalamide C ; mycalamide D
    Language English
    Publishing date 2000-05
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 304325-3
    ISSN 1520-6025 ; 0163-3864
    ISSN (online) 1520-6025
    ISSN 0163-3864
    DOI 10.1021/np990431z
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1144: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  8. Article: Recognition and Respect: Contextualizing the History and Contributions of Black American Plastic Surgeons.

    Glahn, Joshua Zev / Hooper, Rachel C / Butler, Paris D

    Plastic and reconstructive surgery. Global open

    2023  Volume 11, Issue 8, Page(s) e5179

    Abstract: Recently, there has been heightened interest in the history of Black American plastic surgeons and their contributions to the field of plastic and reconstructive surgery (PRS). Despite the increased awareness and attention toward the lack of racial and ... ...

    Abstract Recently, there has been heightened interest in the history of Black American plastic surgeons and their contributions to the field of plastic and reconstructive surgery (PRS). Despite the increased awareness and attention toward the lack of racial and ethnic diversity of the PRS workforce, the history of how PRS became one of the most ethnically segregated surgical specialties remains unexplored. Here, we outline the various political and cultural factors that contributed to the exclusion of Black practitioners from American PRS professional societies. This work contextualizes the rise of American PRS within the Jim Crow era and highlights the cultural significance of reconstructive procedures performed in the treatment of disfigured soldiers. Through this lens, we identify circumstances where Black surgeons were systematically denied opportunities to participate in the emerging specialty. Despite these barriers, we demonstrate how Black physicians established informal networks for professional advancement and shed light on several previously unrecognized contributions to PRS from Black surgeons. In addition, we explore how the inclusion of Black voices in PRS sparked a paradigm shift in the treatment of non-White patients that expanded the cosmetic marketplace in ways that remain significant today. Finally, we situate the ongoing disparities in Black representation in PRS within a broader historical narrative and illustrate how the stories we tell about our past continue to shape the future of our field.
    Language English
    Publishing date 2023-08-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2851682-5
    ISSN 2169-7574 ; 2169-7574
    ISSN (online) 2169-7574
    ISSN 2169-7574
    DOI 10.1097/GOX.0000000000005179
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 7091: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  9. Article ; Online: Cross-Jurisdictional Transmission of Mycobacterium tuberculosis in Maryland and Washington, D.C., 1996–2000, Linked to the Homeless

    Monica Lathan / Leonard Ntaate Mukasa / Nancy Hooper / Jonathan Golub / Nancy Baruch / Donna Mulcahy / William Benjamin / Wendy A. Cronin

    Emerging Infectious Diseases, Vol 8, Iss 11, Pp 1249-

    2002  Volume 1251

    Abstract: From 1996 to 2000, 23 Maryland and Washington, D.C., tuberculosis cases were identified in one six ... to another member; half the patients were associated with a Washington, D.C., homeless shelter ...

    Abstract From 1996 to 2000, 23 Maryland and Washington, D.C., tuberculosis cases were identified in one six-band DNA cluster. Cases were clustered on the basis of their Mycobacterium tuberculosis isolates. Medical record reviews and interviews were conducted to identify epidemiologic linkages. Eighteen (78%) of the 23 case-patients with identical restriction fragment length polymorphism patterns were linked to another member; half the patients were associated with a Washington, D.C., homeless shelter. Molecular epidemiology defined the extent of this large, cross-jurisdictional outbreak.
    Keywords tuberculosis ; molecular epidemiology ; cluster ; homelessness ; United States ; Maryland ; Medicine ; R ; Infectious and parasitic diseases ; RC109-216
    Language English
    Publishing date 2002-11-01T00:00:00Z
    Publisher Centers for Disease Control and Prevention
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  10. Article ; Online: NorA efflux pump mediates

    Truong-Bolduc, Q C / Yonker, L M / Wang, Y / Lawton, B G / Hooper, D C

    Antimicrobial agents and chemotherapy

    2024  Volume 68, Issue 2, Page(s) e0100123

    Abstract: Endogenous transporters ... ...

    Abstract Endogenous transporters protect
    MeSH term(s) Humans ; Child ; Staphylococcus aureus ; Pseudomonas aeruginosa/metabolism ; Pyocyanine/pharmacology ; Bacterial Proteins/metabolism ; Staphylococcal Infections/microbiology ; Anti-Bacterial Agents/pharmacology ; Pseudomonas Infections ; Multidrug Resistance-Associated Proteins/metabolism ; Microbial Sensitivity Tests
    Chemical Substances Pyocyanine (9OQM399341) ; Bacterial Proteins ; Anti-Bacterial Agents ; Multidrug Resistance-Associated Proteins
    Language English
    Publishing date 2024-01-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 217602-6
    ISSN 1098-6596 ; 0066-4804
    ISSN (online) 1098-6596
    ISSN 0066-4804
    DOI 10.1128/aac.01001-23
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 809: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Einzelsignatur: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top