Article ; Online: `Cryo-EM': electron cryomicroscopy, cryo electron microscopy or something else?
2023 Volume 10, Issue Pt 5, Page(s) 519–520
Abstract: Structural biology continues to benefit from an expanding toolkit, which is helping to gain unprecedented insight into the assembly and organization of multi-protein machineries, enzyme mechanisms and ligand/inhibitor binding. During the last ten years, ... ...
| Abstract | Structural biology continues to benefit from an expanding toolkit, which is helping to gain unprecedented insight into the assembly and organization of multi-protein machineries, enzyme mechanisms and ligand/inhibitor binding. During the last ten years, cryoEM has become widely available and has provided a major boost to structure determination of membrane proteins and large multi-protein complexes. Many of the structures have now been made available at resolutions around 2 Å, where fundamental questions regarding enzyme mechanisms can be addressed. Over the years, the abbreviation cryoEM has been understood to stand for different things. We wish the wider community to engage and clarify the definition of cryoEM so that the expanding literature involving cryoEM is unified. |
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| MeSH term(s) | Cryoelectron Microscopy ; Membrane Proteins |
| Chemical Substances | Membrane Proteins |
| Language | English |
| Publishing date | 2023-09-01 |
| Publishing country | England |
| Document type | Journal Article |
| ZDB-ID | 2754953-7 |
| ISSN | 2052-2525 ; 2052-2525 |
| ISSN (online) | 2052-2525 |
| ISSN | 2052-2525 |
| DOI | 10.1107/S2052252523006759 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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