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  1. Article ; Online: Imaging of Trauma in Pregnancy.

    Odedra, Devang / Mellnick, Vincent M / Patlas, Michael N

    Radiologic clinics of North America

    2022  Volume 61, Issue 1, Page(s) 129–139

    Abstract: A pregnant patient with acute trauma is not commonly encountered by clinicians and radiologists. A multidisciplinary approach is key. Although radiography and ultrasound examination are frequently used modalities in the setting of maternal-fetal trauma, ... ...

    Abstract A pregnant patient with acute trauma is not commonly encountered by clinicians and radiologists. A multidisciplinary approach is key. Although radiography and ultrasound examination are frequently used modalities in the setting of maternal-fetal trauma, the fear of radiation should not preclude from carrying out a thorough diagnostic workup of the patient with a computed tomography scan. MRI mainly serves as a problem solving and follow-up modality. After stabilizing the mother, fetal well-being should be assessed with external fetal monitoring and a dedicated obstetric ultrasound examination. Radiologists should be familiar with the sonographic and computed tomography findings of catastrophic entities.
    MeSH term(s) Pregnancy ; Female ; Humans ; Ultrasonography, Prenatal ; Magnetic Resonance Imaging/methods ; Tomography, X-Ray Computed ; Ultrasonography
    Language English
    Publishing date 2022-10-07
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 215712-3
    ISSN 1557-8275 ; 0033-8389
    ISSN (online) 1557-8275
    ISSN 0033-8389
    DOI 10.1016/j.rcl.2022.07.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Magnetic resonance imaging in abdominal trauma-More relevant than ever.

    Odedra, Devang / Scaglione, Mariano / Basilico, Raffaella / Patlas, Michael N

    Canadian Association of Radiologists journal = Journal l'Association canadienne des radiologistes

    2022  Volume 73, Issue 4, Page(s) 612–613

    MeSH term(s) Abdominal Injuries/diagnostic imaging ; Humans ; Magnetic Resonance Imaging/methods ; Wounds, Nonpenetrating
    Language English
    Publishing date 2022-03-02
    Publishing country United States
    Document type Editorial
    ZDB-ID 418190-6
    ISSN 1488-2361 ; 0846-5371 ; 0008-2902
    ISSN (online) 1488-2361
    ISSN 0846-5371 ; 0008-2902
    DOI 10.1177/08465371221080058
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Planar Asymmetries in the

    Dutta, Priyanka / Odedra, Devang / Pohl, Christian

    Frontiers in cell and developmental biology

    2019  Volume 7, Page(s) 209

    Abstract: Formation of the anteroposterior and dorsoventral body axis ... ...

    Abstract Formation of the anteroposterior and dorsoventral body axis in
    Language English
    Publishing date 2019-09-27
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2737824-X
    ISSN 2296-634X
    ISSN 2296-634X
    DOI 10.3389/fcell.2019.00209
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Impact of COVID-19 on Canadian Radiology Residency Training Programs.

    Odedra, Devang / Chahal, Baljot S / Patlas, Michael N

    Canadian Association of Radiologists journal = Journal l'Association canadienne des radiologistes

    2020  Volume 71, Issue 4, Page(s) 482–489

    Abstract: Purpose: The novel coronavirus disease (COVID-19) pandemic has swept the globe, with a domino effect on medical education and training. In this study, we surveyed Canadian radiology residents to understand the impact of the pandemic on their residency ... ...

    Abstract Purpose: The novel coronavirus disease (COVID-19) pandemic has swept the globe, with a domino effect on medical education and training. In this study, we surveyed Canadian radiology residents to understand the impact of the pandemic on their residency training, strategies utilized by the residency programs in mitigating those impacts, and factors important to residents in the selection of educational resources on COVID-19.
    Methods: A 10-item questionnaire was distributed to 460 resident members of the Canadian Association of Radiologists. The survey was open for 2 weeks, with a reminder sent at half-way mark.
    Results: We received 96 responses (response rate: 20.9%). The 4 highest affected domains of training were daytime case volumes (92.4%), daytime schedules (87.4%), internal and external assessments (86.5%), and vacation/travel (83.3%). Virtual teaching rounds (91.7%), change in schedules to allow staying home (78.1%), and virtual/phone readouts (72.9%) were the most utilized strategies by the Canadian radiology residency programs. Overall stress of exposure to the disease was moderate to low (86.5%). A minority of the residents were redeployed (6.2%), although most (68.8%) were on standby for redeployment. Residents preferred published society guidelines (92.3%), review papers (79.3%), video lectures (79.3%), and web tools (76.9%) for learning about COVID-19 imaging manifestations.
    Conclusion: The COVID-19 pandemic has had a significant impact on various domains of the Canadian radiology residency programs, which has been mitigated by several strategies employed by the training programs.
    MeSH term(s) Betacoronavirus ; COVID-19 ; Canada ; Coronavirus Infections/prevention & control ; Humans ; Internship and Residency/methods ; Internship and Residency/statistics & numerical data ; Pandemics/prevention & control ; Pneumonia, Viral/prevention & control ; Radiologists ; Radiology/education ; SARS-CoV-2 ; Surveys and Questionnaires/statistics & numerical data
    Keywords covid19
    Language English
    Publishing date 2020-06-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 418190-6
    ISSN 1488-2361 ; 0846-5371 ; 0008-2902
    ISSN (online) 1488-2361
    ISSN 0846-5371 ; 0008-2902
    DOI 10.1177/0846537120933215
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Dual Energy CT Physics-A Primer for the Emergency Radiologist.

    Odedra, Devang / Narayanasamy, Sabarish / Sabongui, Sandra / Priya, Sarv / Krishna, Satheesh / Sheikh, Adnan

    Frontiers in radiology

    2022  Volume 2, Page(s) 820430

    Abstract: Dual energy CT (DECT) refers to the acquisition of CT images at two energy spectra and can provide information about tissue composition beyond that obtainable by conventional CT. The attenuation of a photon beam varies depends on the atomic number and ... ...

    Abstract Dual energy CT (DECT) refers to the acquisition of CT images at two energy spectra and can provide information about tissue composition beyond that obtainable by conventional CT. The attenuation of a photon beam varies depends on the atomic number and density of the attenuating material and the energy of the incoming photon beam. This differential attenuation of the beam at varying energy levels forms the basis of DECT imaging and enables separation of materials with different atomic numbers but similar CT attenuation. DECT can be used to detect and quantify materials like iodine, calcium, or uric acid. Several post-processing techniques are available to generate virtual non-contrast images, iodine maps, virtual mono-chromatic images, Mixed or weighted images and material specific images. Although initially the concept of dual energy CT was introduced in 1970, it is only over the past two decades that it has been extensively used in clinical practice owing to advances in CT hardware and post-processing capabilities. There are numerous applications of DECT in Emergency radiology including stroke imaging to differentiate intracranial hemorrhage and contrast staining, diagnosis of pulmonary embolism, characterization of incidentally detected renal and adrenal lesions, to reduce beam and metal hardening artifacts, in identification of uric acid renal stones and in the diagnosis of gout. This review article aims to provide the emergency radiologist with an overview of the physics and basic principles of dual energy CT. In addition, we discuss the types of DECT acquisition and post processing techniques including newer advances such as photon-counting CT followed by a brief discussion on the applications of DECT in Emergency radiology.
    Language English
    Publishing date 2022-02-24
    Publishing country Switzerland
    Document type Journal Article ; Review
    ISSN 2673-8740
    ISSN (online) 2673-8740
    DOI 10.3389/fradi.2022.820430
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Autosomal Dominant Polycystic Kidney Disease: Role of Imaging in Diagnosis and Management.

    Odedra, Devang / Sabongui, Sandra / Khalili, Korosh / Schieda, Nicola / Pei, York / Krishna, Satheesh

    Radiographics : a review publication of the Radiological Society of North America, Inc

    2022  Volume 43, Issue 1, Page(s) e220126

    Abstract: Autosomal dominant polycystic kidney disease (ADPKD) is the most common genetic kidney disorder with progressive renal function decline, and disease severity is determined based on the type of genetic mutation. The diagnosis is usually established at ... ...

    Abstract Autosomal dominant polycystic kidney disease (ADPKD) is the most common genetic kidney disorder with progressive renal function decline, and disease severity is determined based on the type of genetic mutation. The diagnosis is usually established at imaging, primarily at US, and is based on age-dependent criteria and the number of visible cysts. ADPKD is classified into class 1 (typical) and class 2 (atypical) according to the Mayo Clinic Imaging Classification (MCIC) system. Height-adjusted total kidney volume (TKV) has emerged as a predictor of future renal function decline and renal failure in ADPKD, and several methods can be used for estimation. MCIC class 1 ADPKD is further subdivided into five types based on height-adjusted TKV (A, B, C, D, and E). Patients with a larger height-adjusted TKV (ie, MCIC 1C-E) are at high risk for progression to end-stage renal disease and will potentially benefit from vasopressin receptor antagonists, which have been shown to reduce the rate of cyst growth and slow renal function decline. Other renal complications primarily relate to hemorrhage within cysts or cyst infections. Subtraction images are key for assessment of complex cysts when malignancy is suspected, as the presence of protein and blood can limit the assessment for an enhancing component. The radiologist has a central role in establishing a diagnosis, excluding mimics, identifying complications, assessing severity, and predicting future renal failure. Interventional radiologists play a therapeutic role in management of complications by cyst drainage, sclerotherapy, or embolization.
    MeSH term(s) Humans ; Polycystic Kidney, Autosomal Dominant/diagnostic imaging ; Polycystic Kidney, Autosomal Dominant/therapy ; Diagnostic Imaging ; Kidney ; Cysts ; Renal Insufficiency
    Language English
    Publishing date 2022-12-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 603172-9
    ISSN 1527-1323 ; 0271-5333
    ISSN (online) 1527-1323
    ISSN 0271-5333
    DOI 10.1148/rg.220126
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Imaging of Blunt Pancreatic Trauma: A Systematic Review.

    Odedra, Devang / Mellnick, Vincent M / Patlas, Michael N

    Canadian Association of Radiologists journal = Journal l'Association canadienne des radiologistes

    2020  Volume 71, Issue 3, Page(s) 344–351

    Abstract: Purpose: Despite several published reports on the value of imaging in acute blunt pancreatic trauma, there remains a large variability in the reported performance of ultrasound (US), computed tomography (CT), and magnetic resonance imaging (MRI). The ... ...

    Abstract Purpose: Despite several published reports on the value of imaging in acute blunt pancreatic trauma, there remains a large variability in the reported performance of ultrasound (US), computed tomography (CT), and magnetic resonance imaging (MRI). The purpose of this study is to present a systematic review on the utility of these imaging modalities in the acute assessment of blunt pancreatic trauma. In addition, a brief overview of the various signs of pancreatic trauma will be presented.
    Methods: Keyword search was performed in MEDLINE, EMBASE, and Web of Science databases for relevant studies in the last 20 years (1999 onward). Titles and abstracts were screened, followed by full-text screening. Inclusion criteria were defined as studies reporting on the effectiveness of imaging modality (US, CT, or MRI) in detecting blunt pancreatic trauma.
    Results: After initial search of 743 studies, a total of 37 studies were included in the final summary. Thirty-six studies were retrospective in nature. Pancreatic injury was the primary study objective in 21 studies. Relevant study population varied from 5 to 299. Seventeen studies compared the imaging findings against intraoperative findings. Seven studies performed separate analysis for pancreatic ductal injuries and 9 studies only investigated ductal injuries. The reported sensitivities for the detection of pancreatic injuries at CT ranged from 33% to 100% and specificity ranged from 62% to 100%. Sensitivity at US ranged from 27% to 96%. The sensitivity at MRI was only reported in 1 study and was 92%.
    Conclusion: There remains a large heterogeneity among reported studies in the accuracy of initial imaging modalities for blunt pancreatic injury. Although technological advances in imaging equipment would be expected to improve accuracy, the current body of literature remains largely divided. There is a need for future studies utilizing the most advanced imaging equipment with appropriately defined gold standards and outcome measures.
    MeSH term(s) Contrast Media ; Humans ; Magnetic Resonance Imaging ; Pancreas/diagnostic imaging ; Pancreas/injuries ; Sensitivity and Specificity ; Tomography, X-Ray Computed ; Ultrasonography ; Wounds, Nonpenetrating/diagnostic imaging
    Chemical Substances Contrast Media
    Language English
    Publishing date 2020-01-31
    Publishing country United States
    Document type Journal Article ; Systematic Review
    ZDB-ID 418190-6
    ISSN 1488-2361 ; 0846-5371 ; 0008-2902
    ISSN (online) 1488-2361
    ISSN 0846-5371 ; 0008-2902
    DOI 10.1177/0846537119888383
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Mechanical stress induces a scalable switch in cortical flow polarization during cytokinesis.

    Singh, Deepika / Odedra, Devang / Dutta, Priyanka / Pohl, Christian

    Journal of cell science

    2019  Volume 132, Issue 19

    Abstract: During animal development, cells need to sense and adapt to mechanical forces from their environment. Ultimately, these forces are transduced through the actomyosin cortex. How the cortex simultaneously responds to and creates forces during cytokinesis ... ...

    Abstract During animal development, cells need to sense and adapt to mechanical forces from their environment. Ultimately, these forces are transduced through the actomyosin cortex. How the cortex simultaneously responds to and creates forces during cytokinesis is not well understood. Here we show that, under mechanical stress, cortical actomyosin flow can switch polarization during cytokinesis in the
    MeSH term(s) Actin Cytoskeleton/metabolism ; Actins/metabolism ; Actomyosin/metabolism ; Animals ; Caenorhabditis elegans ; Caenorhabditis elegans Proteins/metabolism ; Cell Division/physiology ; Cytokinesis/genetics ; Cytokinesis/physiology ; Kymography ; Microtubules/metabolism ; Spindle Apparatus/metabolism ; Stress, Mechanical
    Chemical Substances Actins ; Caenorhabditis elegans Proteins ; Actomyosin (9013-26-7)
    Language English
    Publishing date 2019-10-09
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2993-2
    ISSN 1477-9137 ; 0021-9533
    ISSN (online) 1477-9137
    ISSN 0021-9533
    DOI 10.1242/jcs.231357
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Dual Energy CT Physics—A Primer for the Emergency Radiologist

    Devang Odedra / Sabarish Narayanasamy / Sandra Sabongui / Sarv Priya / Satheesh Krishna / Adnan Sheikh

    Frontiers in Radiology, Vol

    2022  Volume 2

    Abstract: Dual energy CT (DECT) refers to the acquisition of CT images at two energy spectra and can provide information about tissue composition beyond that obtainable by conventional CT. The attenuation of a photon beam varies depends on the atomic number and ... ...

    Abstract Dual energy CT (DECT) refers to the acquisition of CT images at two energy spectra and can provide information about tissue composition beyond that obtainable by conventional CT. The attenuation of a photon beam varies depends on the atomic number and density of the attenuating material and the energy of the incoming photon beam. This differential attenuation of the beam at varying energy levels forms the basis of DECT imaging and enables separation of materials with different atomic numbers but similar CT attenuation. DECT can be used to detect and quantify materials like iodine, calcium, or uric acid. Several post-processing techniques are available to generate virtual non-contrast images, iodine maps, virtual mono-chromatic images, Mixed or weighted images and material specific images. Although initially the concept of dual energy CT was introduced in 1970, it is only over the past two decades that it has been extensively used in clinical practice owing to advances in CT hardware and post-processing capabilities. There are numerous applications of DECT in Emergency radiology including stroke imaging to differentiate intracranial hemorrhage and contrast staining, diagnosis of pulmonary embolism, characterization of incidentally detected renal and adrenal lesions, to reduce beam and metal hardening artifacts, in identification of uric acid renal stones and in the diagnosis of gout. This review article aims to provide the emergency radiologist with an overview of the physics and basic principles of dual energy CT. In addition, we discuss the types of DECT acquisition and post processing techniques including newer advances such as photon-counting CT followed by a brief discussion on the applications of DECT in Emergency radiology.
    Keywords dual energy (CT) ; physics ; emergency radiology ; material decomposition ; CT ; Medical physics. Medical radiology. Nuclear medicine ; R895-920
    Subject code 535
    Language English
    Publishing date 2022-02-01T00:00:00Z
    Publisher Frontiers Media S.A.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: A 2019 international survey to assess trends in follow-up imaging of blunt splenic trauma.

    Odedra, Devang / Mellnick, Vincent / Patlas, Michael

    Emergency radiology

    2019  Volume 27, Issue 1, Page(s) 51–56

    Abstract: Purpose: There are no published guidelines on the follow-up imaging of non-operatively managed blunt splenic trauma (BST). We conducted an international survey of emergency radiologists to determine the ideal patient population, time period, and ... ...

    Abstract Purpose: There are no published guidelines on the follow-up imaging of non-operatively managed blunt splenic trauma (BST). We conducted an international survey of emergency radiologists to determine the ideal patient population, time period, and technique for follow-up imaging of BST.
    Methods: An anonymous 10-question online survey was distributed via email to 34 emergency radiologists around the world. The survey was open for a 2-week period in 2019. A commercially available website (SurveyMonkey®) was used for survey generation and data acquisition.
    Results: We received 29 responses (85% response rate) primarily from USA, Canada, and Europe. Majority of the institutions handled > 1000 trauma cases (69%). The initial protocol consisted of arterial and portal venous phases (PVP) in 72% of responses. Sixty-two percent of the institutions did not have a routine protocol for follow-up imaging of BST. There was no consensus on which patients received follow-up imaging. The most frequent responses had been case-per-case basis or injuries above a set AAST grade (42% and 37%, respectively). There was no set time period for follow-up imaging, but MDCT was most often performed at 24-48 h. Dual-phase protocol was utilized most commonly (69%). Majority of the institutions (88%) utilized angioembolization for hemodynamically stable patients with contained vascular injury or active extravasation.
    Conclusion: There is no consensus on the optimal patient population or time period for follow-up imaging of BST. A dual-phase follow-up MDCT protocol is utilized for follow-up by majority of institutions.
    MeSH term(s) Continuity of Patient Care/trends ; Diagnostic Imaging/trends ; Female ; Humans ; Internationality ; Male ; Practice Patterns, Physicians'/trends ; Spleen/injuries ; Surveys and Questionnaires ; Wounds, Nonpenetrating/diagnostic imaging
    Language English
    Publishing date 2019-11-06
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1425144-9
    ISSN 1438-1435 ; 1070-3004
    ISSN (online) 1438-1435
    ISSN 1070-3004
    DOI 10.1007/s10140-019-01734-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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