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  1. Article ; Online: Hot Topics in the Clinical Practice Guidelines for Treatment of Male Lower Urinary Tract Symptoms due to Benign Prostatic Obstruction.

    Gravas, Stavros

    European urology focus

    2022  Volume 8, Issue 2, Page(s) 396–398

    Abstract: Clinical practice guidelines (CPGs) are systematically developed statements to assist practitioners in patient decisions about appropriate health care. Appropriate methodologies and rigorous strategies are required to achieve high-quality CPGs. However, ... ...

    Abstract Clinical practice guidelines (CPGs) are systematically developed statements to assist practitioners in patient decisions about appropriate health care. Appropriate methodologies and rigorous strategies are required to achieve high-quality CPGs. However, several challenges may occur during the development of guidelines. This article highlights current hot topics related to the development of guidelines for the management of non-neurogenic male lower urinary tract symptoms (LUTS) including benign prostatic obstruction (BPO). Challenges include: (1) periodic updating of guidelines because of the rapid and continuous accumulation of new evidence and a range of emerging treatment options; (2) the requirements for inclusion of new interventions in guidelines; (3) inclusion of the values and preferences of patients with LUTS who have different needs and characteristics; and (4) a need to improve guideline implementation and adherence. Actions to overcome these challenges are also discussed. PATIENT SUMMARY: Guidelines are considered to improve the quality of clinical decisions by helping doctors and contributing to the consistency of care. The development and successful translation into clinical practice of guidelines on male lower urinary tract symptoms require management of several issues, including the identification and incorporation of patients' values and preferences.
    MeSH term(s) Humans ; Male ; Lower Urinary Tract Symptoms/diagnosis ; Lower Urinary Tract Symptoms/etiology ; Lower Urinary Tract Symptoms/therapy ; Prostatic Hyperplasia/complications ; Prostatic Hyperplasia/diagnosis ; Prostatic Hyperplasia/therapy ; Practice Guidelines as Topic
    Language English
    Publishing date 2022-03-23
    Publishing country Netherlands
    Document type Journal Article
    ISSN 2405-4569
    ISSN (online) 2405-4569
    DOI 10.1016/j.euf.2022.03.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: TURPxit or not: the guidelines perspective-Panta Rhei.

    Gravas, Stavros

    World journal of urology

    2020  Volume 39, Issue 7, Page(s) 2399–2400

    MeSH term(s) Humans ; Lower Urinary Tract Symptoms/etiology ; Lower Urinary Tract Symptoms/surgery ; Male ; Practice Guidelines as Topic ; Prostatic Hyperplasia/complications ; Prostatic Hyperplasia/surgery ; Transurethral Resection of Prostate/standards
    Language English
    Publishing date 2020-11-10
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 380333-8
    ISSN 1433-8726 ; 0724-4983
    ISSN (online) 1433-8726
    ISSN 0724-4983
    DOI 10.1007/s00345-020-03519-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Unveiling prostatic inflammation to optimize management of lower urinary tract symptoms: a discussion with experts.

    Gacci, Mauro / Nunzio, Cosimo De / Gravas, Stavros

    Biomarkers in medicine

    2023  Volume 17, Issue 18, Page(s) 739–745

    Abstract: Benign prostatic obstruction (BPO) and associated lower urinary tract symptoms (LUTS) are common conditions in men, which increase in frequency and severity with age, and have a significant impact on quality of life. Chronic prostatic inflammation is ... ...

    Abstract Benign prostatic obstruction (BPO) and associated lower urinary tract symptoms (LUTS) are common conditions in men, which increase in frequency and severity with age, and have a significant impact on quality of life. Chronic prostatic inflammation is increasingly being recognized as a key component of BPO. This may lead to new targets for the management of BPO/LUTS. This podcast is based on presentations from a symposium titled 'Unveiling prostatic inflammation to optimize LUTS management' held at the European Association of Urology 2023 Congress. The presenters outline evidence of a role for prostatic inflammation in the development and progression of BPO/LUTS, approaches to the identification of biomarkers of inflammation, and the implications of prostatic inflammation for the optimal management of BPO/LUTS.
    MeSH term(s) Humans ; Male ; Inflammation ; Lower Urinary Tract Symptoms/diagnosis ; Prostatic Hyperplasia/complications ; Quality of Life ; Prostatic Diseases/complications
    Language English
    Publishing date 2023-11-16
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2481014-9
    ISSN 1752-0371 ; 1752-0363
    ISSN (online) 1752-0371
    ISSN 1752-0363
    DOI 10.2217/bmm-2023-0365
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Prostate Volume as a Risk Factor for Lower Urinary Tract Symptoms: The Quest Continues.

    Gravas, Stavros

    European urology

    2016  Volume 69, Issue 5, Page(s) 892–893

    Language English
    Publishing date 2016-05
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 193790-x
    ISSN 1873-7560 ; 1421-993X ; 0302-2838
    ISSN (online) 1873-7560 ; 1421-993X
    ISSN 0302-2838
    DOI 10.1016/j.eururo.2015.12.035
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Greek validation of the user version of the Mobile Application Rating Scale (uMARS).

    Chasiotis, Georgios / Stoyanov, Stoyan R / Karatzas, Anastasios / Gravas, Stavros

    The Journal of international medical research

    2023  Volume 51, Issue 3, Page(s) 3000605231161213

    Abstract: Objective: The original user version of the Mobile Application Rating Scale (uMARS) is an English-language questionnaire that was designed to allow non-expert app users to assess the quality of health apps. We aimed to translate into the Greek language ... ...

    Abstract Objective: The original user version of the Mobile Application Rating Scale (uMARS) is an English-language questionnaire that was designed to allow non-expert app users to assess the quality of health apps. We aimed to translate into the Greek language and validate the uMARS.
    Methods: This was a qualitative prospective study. The World Health Organization translation process was followed and a readily available and free-of-charge app was used for the validation process. Internal consistency and reliability were tested twice within one month by 91 Greek medical students.
    Results: The total uMARS score showed excellent internal consistency (Cronbach's alpha = 0.86). The internal consistencies of its subscales were also very high (engagement alpha = 0.71; functionality alpha = 0.71; aesthetics alpha = 0.67; information alpha = 0.63), with the notable exception of the satisfaction alpha, which was 0.61. The uMARS total score demonstrated almost perfect agreement levels in most of the subscales according to the r
    Conclusions: The Greek uMARS is a reliable and valid tool for assessing the quality of mobile apps.
    MeSH term(s) Humans ; Mobile Applications ; Reproducibility of Results ; Prospective Studies ; Surveys and Questionnaires ; Psychometrics
    Language English
    Publishing date 2023-02-27
    Publishing country England
    Document type Journal Article
    ZDB-ID 184023-x
    ISSN 1473-2300 ; 0300-0605 ; 0142-2596
    ISSN (online) 1473-2300
    ISSN 0300-0605 ; 0142-2596
    DOI 10.1177/03000605231161213
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Re: Drug Adherence and Clinical Outcomes for Patients Under Pharmacological Therapy for Lower Urinary Tract Symptoms Related to Benign Prostatic Hyperplasia: Population-based Cohort Study.

    Gravas, Stavros

    European urology

    2015  Volume 68, Issue 2, Page(s) 338–339

    MeSH term(s) 5-alpha Reductase Inhibitors/therapeutic use ; Adrenergic alpha-Antagonists/therapeutic use ; Humans ; Lower Urinary Tract Symptoms/drug therapy ; Male ; Prostatic Hyperplasia/drug therapy
    Chemical Substances 5-alpha Reductase Inhibitors ; Adrenergic alpha-Antagonists
    Language English
    Publishing date 2015-08
    Publishing country Switzerland
    Document type Comment ; Journal Article
    ZDB-ID 193790-x
    ISSN 1873-7560 ; 1421-993X ; 0302-2838
    ISSN (online) 1873-7560 ; 1421-993X
    ISSN 0302-2838
    DOI 10.1016/j.eururo.2015.03.015
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Greek validation of the user version of the Mobile Application Rating Scale (uMARS)

    Georgios Chasiotis / Stoyan R Stoyanov / Anastasios Karatzas / Stavros Gravas

    Journal of International Medical Research, Vol

    2023  Volume 51

    Abstract: Objective The original user version of the Mobile Application Rating Scale (uMARS) is an English-language questionnaire that was designed to allow non-expert app users to assess the quality of health apps. We aimed to translate into the Greek language ... ...

    Abstract Objective The original user version of the Mobile Application Rating Scale (uMARS) is an English-language questionnaire that was designed to allow non-expert app users to assess the quality of health apps. We aimed to translate into the Greek language and validate the uMARS. Methods This was a qualitative prospective study. The World Health Organization translation process was followed and a readily available and free-of-charge app was used for the validation process. Internal consistency and reliability were tested twice within one month by 91 Greek medical students. Results The total uMARS score showed excellent internal consistency (Cronbach’s alpha = 0.86). The internal consistencies of its subscales were also very high (engagement alpha = 0.71; functionality alpha = 0.71; aesthetics alpha = 0.67; information alpha = 0.63), with the notable exception of the satisfaction alpha, which was 0.61. The uMARS total score demonstrated almost perfect agreement levels in most of the subscales according to the r WG index from baseline to 1 month. Conclusions The Greek uMARS is a reliable and valid tool for assessing the quality of mobile apps.
    Keywords Medicine (General) ; R5-920
    Subject code 027
    Language English
    Publishing date 2023-03-01T00:00:00Z
    Publisher SAGE Publishing
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Reply to Meny Lv, Xufei Luo, and Yaolong Chen's Letter to the Editor re: Mauro Gacci, Vasileios I. Sakalis, Markos Karavitakis, et al. European Association of Urology Guidelines on Male Urinary Incontinence. Eur Urol. In press. https://doi.org/10.1016/j.eururo.2022.05.012.

    Gacci, Mauro / Sakalis, Vasileios I / Karavitakis, Markos / Gravas, Stavros

    European urology

    2022  Volume 82, Issue 4, Page(s) e119–e120

    MeSH term(s) Humans ; Male ; Urinary Incontinence ; Urology
    Language English
    Publishing date 2022-08-06
    Publishing country Switzerland
    Document type Letter ; Comment
    ZDB-ID 193790-x
    ISSN 1873-7560 ; 1421-993X ; 0302-2838
    ISSN (online) 1873-7560 ; 1421-993X
    ISSN 0302-2838
    DOI 10.1016/j.eururo.2022.07.029
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Mind the gap: management of benign prostatic obstruction (BPO) surgical candidates on antithrombotics.

    Dimitropoulos, Konstantinos / Gravas, Stavros

    World journal of urology

    2019  Volume 38, Issue 1, Page(s) 247–248

    MeSH term(s) Anticoagulants ; Fibrinolytic Agents ; Humans ; Hyperplasia ; Male ; Prostatic Hyperplasia ; Volatilization
    Chemical Substances Anticoagulants ; Fibrinolytic Agents
    Language English
    Publishing date 2019-01-03
    Publishing country Germany
    Document type Letter ; Comment
    ZDB-ID 380333-8
    ISSN 1433-8726 ; 0724-4983
    ISSN (online) 1433-8726
    ISSN 0724-4983
    DOI 10.1007/s00345-018-02625-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Latest Evidence on Post-Prostatectomy Urinary Incontinence.

    Gacci, Mauro / De Nunzio, Cosimo / Sakalis, Vasileios / Rieken, Malte / Cornu, Jean-Nicolas / Gravas, Stavros

    Journal of clinical medicine

    2023  Volume 12, Issue 3

    Abstract: A radical prostatectomy is frequently used as the first-line treatment for men with prostate cancer. Persistent urinary incontinence after surgery is one of the most severe adverse events. We report the results of a comprehensive literature search ... ...

    Abstract A radical prostatectomy is frequently used as the first-line treatment for men with prostate cancer. Persistent urinary incontinence after surgery is one of the most severe adverse events. We report the results of a comprehensive literature search focused on post-prostatectomy urinary incontinence (PPI), performed by a panel of experts on non-neurogenic lower urinary tract symptoms. The data on the prevalence and timing of PPI are very heterogeneous. The etiology of PPI can be multifactorial and mainly dependent on patient characteristics, lower urinary tract function or surgical issues. The medical history with a physical examination, the use of validated questionnaires with a voiding diary and pad tests are determinants in identifying the contributing factors and choosing the right treatment. Lifestyle intervention and urinary containment are the most frequently used strategies for the conservative management of PPI, while antimuscarinics, beta-3 agonists and duloxetine (off-label) are drugs indicated to manage PPI with a concomitant overactive bladder. Surgical therapies for the management of post-prostatectomy SUI include non-adjustable trans-obturator slings in men with mild-to-moderate incontinence and an artificial urinary sphincter in men with moderate-to-severe incontinence.
    Language English
    Publishing date 2023-02-02
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm12031190
    Database MEDical Literature Analysis and Retrieval System OnLINE

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