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Article ; Online: Using routine clinical and administrative data to produce information on mental health in Brazil.

Alves, Flavia Jôse Oliveira / Machado, Daiane Borges / Araujo, Jacyra Azevedo Paiva de / Castro-de-Araujo, Luis Fernando Silva

Revista de saude publica

2022 Volume 56, Page(s) 81

MeSH term(s)	Brazil ; Humans ; Mental Disorders/epidemiology ; Mental Health ; Mental Health Services
Language	English
Publishing date	2022-09-12
Publishing country	Brazil
Document type	Letter
ZDB-ID	732179-x
ISSN	1518-8787 ; 0034-8910
ISSN (online)	1518-8787
ISSN	0034-8910
DOI	10.11606/s1518-8787.2022056004818
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Article ; Online: Impact of COVID-19 on mental health in a Low and Middle-Income Country.

Castro-de-Araujo, Luís Fernando Silva / Machado, Daiane Borges

Ciencia & saude coletiva

2020 Volume 25, Issue suppl 1, Page(s) 2457–2460

Abstract: Mental disorders (MD) are commonly comorbid with cardiovascular, metabolic, and some infectious diseases. Since the current SARS-CoV-2 epidemic is affecting the most multimorbid individuals, we might expect that the epidemic will be particularly ... ...

Abstract	Mental disorders (MD) are commonly comorbid with cardiovascular, metabolic, and some infectious diseases. Since the current SARS-CoV-2 epidemic is affecting the most multimorbid individuals, we might expect that the epidemic will be particularly problematic for people with MD. Understanding the burden of an outbreak on mental health is fundamental to effective action towards containing the spread of the disease, as psychopathology might reduce endurance during the lockdown. This can potentially reduce adhesion to ongoing treatment resulting in avoidable recurrence of a disorder. Additionally, there is the stress caused by the eminent risk of infection or economic uncertainty, especially in low-middle income settings. This is an overview on the expected influence of the COVID-19 on mental health from a research group that has not long ago been involved in the Zika epidemic. It aims to discuss the effects of the pandemic on a Low and Middle-Income country (LMIC), Brazil.
MeSH term(s)	Betacoronavirus ; Bipolar Disorder/psychology ; Bipolar Disorder/therapy ; Brazil ; COVID-19 ; Caregivers ; Coronavirus Infections/epidemiology ; Coronavirus Infections/psychology ; Dementia/nursing ; Developing Countries ; Family ; Health Services Accessibility ; Humans ; Mental Disorders/drug therapy ; Mental Disorders/epidemiology ; Mental Disorders/psychology ; Mental Health ; Multimorbidity ; Pandemics ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/psychology ; SARS-CoV-2 ; Sensation ; Social Isolation
Keywords	covid19
Language	English
Publishing date	2020-04-25
Publishing country	Brazil
Document type	Journal Article
ZDB-ID	2078799-6
ISSN	1678-4561 ; 1678-4561
ISSN (online)	1678-4561
ISSN	1678-4561
DOI	10.1590/1413-81232020256.1.10932020
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Article ; Online: Using routine clinical and administrative data to produce information on mental health in Brazil

Flavia Jôse Oliveira Alves / Daiane Borges Machado / Jacyra Azevedo Paiva de Araujo / Luis Fernando Silva Castro-de-Araujo

Revista de Saúde Pública, Vol

2022 Volume 56

Keywords	Public aspects of medicine ; RA1-1270
Language	English
Publishing date	2022-08-01T00:00:00Z
Publisher	Universidade de São Paulo
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Impact of COVID-19 on mental health in a Low and Middle-Income Country

Castro-de-Araujo, Luís Fernando Silva / Machado, Daiane Borges

Cien Saude Colet

Abstract	Mental disorders (MD) are commonly comorbid with cardiovascular, metabolic, and some infectious diseases. Since the current SARS-CoV-2 epidemic is affecting the most multimorbid individuals, we might expect that the epidemic will be particularly problematic for people with MD. Understanding the burden of an outbreak on mental health is fundamental to effective action towards containing the spread of the disease, as psychopathology might reduce endurance during the lockdown. This can potentially reduce adhesion to ongoing treatment resulting in avoidable recurrence of a disorder. Additionally, there is the stress caused by the eminent risk of infection or economic uncertainty, especially in low-middle income settings. This is an overview on the expected influence of the COVID-19 on mental health from a research group that has not long ago been involved in the Zika epidemic. It aims to discuss the effects of the pandemic on a Low and Middle-Income country (LMIC), Brazil.
Keywords	covid19
Publisher	WHO
Document type	Article
Note	WHO #Covidence: #595544
Database	COVID19

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Article: Patterns of multimorbidity and some psychiatric disorders: A systematic review of the literature.

Castro-de-Araujo, Luis Fernando Silva / Cortes, Fanny / de Siqueira Filha, Noêmia Teixeira / Rodrigues, Elisângela da Silva / Machado, Daiane Borges / de Araujo, Jacyra Azevedo Paiva / Lewis, Glyn / Denaxas, Spiros / Barreto, Mauricio L

Frontiers in psychology

2022 Volume 13, Page(s) 940978

Abstract: Objective: The presence of two or more chronic diseases results in worse clinical outcomes than expected by a simple combination of diseases. This synergistic effect is expected to be higher when combined with some conditions, depending on the number ... ...

Abstract	Objective: The presence of two or more chronic diseases results in worse clinical outcomes than expected by a simple combination of diseases. This synergistic effect is expected to be higher when combined with some conditions, depending on the number and severity of diseases. Multimorbidity is a relatively new term, with the first fundamental definitions appearing in 2015. Studies usually define it as the presence of at least two chronic medical illnesses. However, little is known regarding the relationship between mental disorders and other non-psychiatric chronic diseases. This review aims at investigating the association between some mental disorders and non-psychiatric diseases, and their pattern of association. Methods: We performed a systematic approach to selecting papers that studied relationships between chronic conditions that included one mental disorder from 2015 to 2021. These were processed using Covidence, including quality assessment. Results: This resulted in the inclusion of 26 papers in this study. It was found that there are strong associations between depression, psychosis, and multimorbidity, but recent studies that evaluated patterns of association of diseases (usually using clustering methods) had heterogeneous results. Quality assessment of the papers generally revealed low quality among the included studies. Conclusions: There is evidence of an association between depressive disorders, anxiety disorders, and psychosis with multimorbidity. Studies that tried to examine the patterns of association between diseases did not find stable results. Systematic review registration: https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42021216101, identifier: CRD42021216101.
Language	English
Publishing date	2022-09-16
Publishing country	Switzerland
Document type	Systematic Review
ZDB-ID	2563826-9
ISSN	1664-1078
ISSN	1664-1078
DOI	10.3389/fpsyg.2022.940978
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Article ; Online: Main and moderated effects of multimorbidity and depressive symptoms on cognition.

de Araujo, Jacyra Azevedo Paiva / Xavier, Érika Fialho Morais / Rodrigues, Elisângela da Silva / Machado, Daiane Borges / Barreto, Marcos E / Kanaan, Richard A / Barreto, Mauricio L / Castro-de-Araujo, Luis Fernando Silva

Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999)

2022 Volume 44, Issue 6, Page(s) 644–649

Abstract: Objective: Multimorbidity, or the occurrence of two or more chronic conditions, is a global challenge, with implications for mortality, morbidity, disability, and life quality. Psychiatric disorders are common among the chronic diseases that affect ... ...

Abstract	Objective: Multimorbidity, or the occurrence of two or more chronic conditions, is a global challenge, with implications for mortality, morbidity, disability, and life quality. Psychiatric disorders are common among the chronic diseases that affect patients with multimorbidity. It is still not well understood whether psychiatric symptoms, especially depressive symptoms, moderate the effect of multimorbidity on cognition. Methods: We used a large (n=2,681) dataset to assess whether depressive symptomatology moderates the effect of multimorbidity on cognition using structural equation modelling. Results: It was found that the more depressive symptoms and chronic conditions, the worse the cognitive performance, and the higher the educational level, the better the cognitive performance. We found a significant but weak (0.009; p = 0.04) moderating effect. Conclusion: We have provided the first estimate of the moderating effect of depression on the relation between multimorbidity and cognition, which was small. Although this moderation has been implied by many previous studies, it was never previously estimated.
MeSH term(s)	Humans ; Depression/epidemiology ; Depression/psychology ; Multimorbidity ; Quality of Life/psychology ; Chronic Disease ; Cognition
Language	English
Publishing date	2022-09-30
Publishing country	Brazil
Document type	Journal Article
ZDB-ID	2024119-7
ISSN	1809-452X ; 1809-452X
ISSN (online)	1809-452X
ISSN	1809-452X
DOI	10.47626/1516-4446-2022-2601
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Article ; Online: Multimorbidity associated with anxiety symptomatology in post-COVID patients.

Azevedo, Milena Nogueira / Rodrigues, Elisângela da Silva / Passos, Emília Augusta Franz Vieira / Filho, Márcio Andrade Barreto / Barreto, Ana Paula Andrade / Lima, Marcelo Chalhoub Coelho / Barreto, Mauricio Lima / Castro-de-Araujo, Luis Fernando Silva

Psychiatry research

2022 Volume 309, Page(s) 114427

Abstract: The COVID-19 pandemic hit individuals with chronic conditions the hardest. It is known that anxiety symptoms are frequent in post-COVID conditions. We want to examine whether multimorbidity is associated with anxiety in post-COVID patients. We reported ... ...

Abstract	The COVID-19 pandemic hit individuals with chronic conditions the hardest. It is known that anxiety symptoms are frequent in post-COVID conditions. We want to examine whether multimorbidity is associated with anxiety in post-COVID patients. We reported descriptive statistics from 389 post-COVID patients and perform a linear regression with anxiety symptoms measured using the Hospital Anxiety and Depression (HAD) scale. For each extra chronic condition, there was a mean increase of 0.11 in the HAD-anxiety score. However, there was a reduction for age and being male. These findings can potentially help policy-makers better organize post-COVID health services and improve patients care.
MeSH term(s)	Anxiety/diagnosis ; Anxiety/epidemiology ; COVID-19 ; Depression/diagnosis ; Humans ; Male ; Multimorbidity ; Pandemics ; SARS-CoV-2
Language	English
Publishing date	2022-01-30
Publishing country	Ireland
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	445361-x
ISSN	1872-7123 ; 1872-7506 ; 0925-4927 ; 0165-1781
ISSN (online)	1872-7123 ; 1872-7506
ISSN	0925-4927 ; 0165-1781
DOI	10.1016/j.psychres.2022.114427
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Article ; Online: Multimorbidity worsened anxiety and depression symptoms during the COVID-19 pandemic in Brazil.

Castro-de-Araujo, Luis Fernando Silva / Rodrigues, Elisângela da Silva / Machado, Daiane Borges / Henriques, Claudio Maierovitch Pessanha / Verotti, Mariana Pastorello / Gonçalves, Alessandra Queiroga / Duarte-Salles, Talita / Kanaan, Richard A / Barreto, Mauricio Lima / Lewis, Glyn / Barbosa, Jakeline Ribeiro

Journal of affective disorders

2022 Volume 314, Page(s) 86–93

Abstract: Multimorbidity is a global health issue impacting the quality of life of all ages. Multimorbidity with a mental disorder is little studied and is likely to have been affected by the COVID-19 pandemic. We used a survey of 14,007 respondents living in ... ...

Abstract	Multimorbidity is a global health issue impacting the quality of life of all ages. Multimorbidity with a mental disorder is little studied and is likely to have been affected by the COVID-19 pandemic. We used a survey of 14,007 respondents living in Brazil to investigate whether people who already had at least one chronic medical condition had more depression and anxiety symptoms during social distancing in 2020. Generalized linear models and structural equation modelling were used to estimate the effects. A 19 % and 15 % increase in depressive symptoms were found in females and males, respectively, for each unit of increase in the observed value of reported chronic disease. Older subjects presented fewer symptoms of depression and anxiety. There was a 16 % increase in anxiety symptoms in females for each unit increase in the reported chronic disease variable and a 14 % increase in males. Younger subjects were more affected by anxiety symptoms in a dose-response fashion. High income was significantly related to fewer depressive and anxiety symptoms in both males and females. Physical activity was significantly associated with fewer anxiety and depression symptoms. Structural equation modelling confirmed these results and provided further insight into the hypothesised paths.
MeSH term(s)	Anxiety/diagnosis ; Anxiety/epidemiology ; Brazil/epidemiology ; COVID-19/epidemiology ; Chronic Disease ; Depression/diagnosis ; Depression/epidemiology ; Female ; Humans ; Male ; Multimorbidity ; Pandemics ; Quality of Life
Language	English
Publishing date	2022-07-07
Publishing country	Netherlands
Document type	Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
ZDB-ID	135449-8
ISSN	1573-2517 ; 0165-0327
ISSN (online)	1573-2517
ISSN	0165-0327
DOI	10.1016/j.jad.2022.07.005
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Article ; Online: The impact of social drivers, conditional cash transfers and their mechanisms on the mental health of the young; an integrated retrospective and forecasting approach using the 100 million Brazilian Cohort: A study protocol.

Machado, Daiane Borges / Azevedo Paiva de Araujo, Jacyra / Alves, Flávia Jôse Oliveira / Fernando Silva Castro-de-Araujo, Luis / da Silva Rodrigues, Elisângela / Fialho Morais Xavier, Erika / Lins Rodrigues, Rodrigo / Rasella, Davide / Naslund, John / Patel, Vikram / L Barreto, Mauricio

PloS one

2022 Volume 17, Issue 10, Page(s) e0272481

Abstract: Background: Physical, emotional, and social changes, including exposure to poverty, abuse, or violence, increases youth vulnerability to mental illness. These factors interfere with development, limit opportunities, and hamper achievement of a ... ...

Abstract	Background: Physical, emotional, and social changes, including exposure to poverty, abuse, or violence, increases youth vulnerability to mental illness. These factors interfere with development, limit opportunities, and hamper achievement of a fulfilling life as adults. Addressing these issues can lead to improved outcomes at the population level and better cost-effectiveness for health services. Cash transfer programs have been a promising way to address social drivers for poor mental health. However, it is still unclear which pathways and mechanisms explain the association between socioeconomic support and lower mental illness among youth. Therefore, we will evaluate the effect of social drivers on youth mental health-related hospitalizations and suicide, test mechanisms and pathways of a countrywide socioeconomic intervention, and examine the timing of the intervention during the life course. Methods: We will combine individual-level data from youth national hospitalization, mental health disorders and attempted suicide, suicide registries and notifications of violence, with large-scale databases, including "The 100 Million Brazilian Cohort", over an 18-year period (2001-2018). Several approaches will be used for the retrospective quasi-experimental impact evaluations, such as Regression Discontinuity Designs, Propensity Score Matching and difference-in-differences, combined with multivariable regressions for cohort analyses. We will run multivariate regressions based on hierarchical analysis approach to evaluate the association between important social drivers (mental health care, demographic and economic aspects) on mental health-related hospitalizations and suicide among youth. Furthermore, we will perform microsimulations to generate projections regarding how mental health-related hospitalizations and suicide trends will be in the future based on the current state, and how BFP implementation scenarios will affect these trends. Discussion: The results of this project will be of vital importance to guide policies and programs to improve mental health and reduce mental health-related hospitalizations and suicide in youth. It will provide information to improve the effectiveness of these programs worldwide. If cash transfers can decrease mental health problems among youth and reduce suicide.
MeSH term(s)	Adolescent ; Adult ; Brazil/epidemiology ; Financial Statements ; Humans ; Mental Disorders ; Mental Health ; Retrospective Studies
Language	English
Publishing date	2022-10-06
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID	2267670-3
ISSN	1932-6203 ; 1932-6203
ISSN (online)	1932-6203
ISSN	1932-6203
DOI	10.1371/journal.pone.0272481
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Article ; Online: Impact of COVID-19 on mental health in a Low and Middle-Income Country

Castro-de-Araujo, Luís Fernando Silva / Machado, Daiane Borges

Ciência & Saúde Coletiva v.25 suppl.1 2020

2020

Abstract: Abstract Mental disorders (MD) are commonly comorbid with cardiovascular, metabolic, and some infectious diseases. Since the current SARS-CoV-2 epidemic is affecting the most multimorbid individuals, we might expect that the epidemic will be particularly ...

Abstract	Abstract Mental disorders (MD) are commonly comorbid with cardiovascular, metabolic, and some infectious diseases. Since the current SARS-CoV-2 epidemic is affecting the most multimorbid individuals, we might expect that the epidemic will be particularly problematic for people with MD. Understanding the burden of an outbreak on mental health is fundamental to effective action towards containing the spread of the disease, as psychopathology might reduce endurance during the lockdown. This can potentially reduce adhesion to ongoing treatment resulting in avoidable recurrence of a disorder. Additionally, there is the stress caused by the eminent risk of infection or economic uncertainty, especially in low-middle income settings. This is an overview on the expected influence of the COVID-19 on mental health from a research group that has not long ago been involved in the Zika epidemic. It aims to discuss the effects of the pandemic on a Low and Middle-Income country (LMIC), Brazil.
Keywords	COVID-19 ; Mental health ; Brazil ; Dementias ; Bipolar disorder ; covid19
Language	English
Publishing date	2020-06-01
Publisher	ABRASCO - Associação Brasileira de Saúde Coletiva
Publishing country	br
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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