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  1. Article: The Relationship of

    Soto-Aceves, Martin P / Smalley, Nicole E / Schaefer, Amy L / Greenberg, E Peter

    bioRxiv : the preprint server for biology

    2024  

    Abstract: The opportunistic ... ...

    Abstract The opportunistic pathogen
    Language English
    Publishing date 2024-03-22
    Publishing country United States
    Document type Preprint
    DOI 10.1101/2024.03.22.586172
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Relationship of the transcription factor MexT to quorum sensing and virulence in

    Kostylev, Maxim / Smalley, Nicole E / Chao, Man Hou / Greenberg, E Peter

    Journal of bacteriology

    2023  Volume 205, Issue 12, Page(s) e0022623

    Abstract: Importance: Pseudomonas ... ...

    Abstract Importance: Pseudomonas aeruginosa
    MeSH term(s) Transcription Factors/metabolism ; Pseudomonas aeruginosa/metabolism ; Quorum Sensing/genetics ; Virulence ; Gene Expression Regulation, Bacterial ; Bacterial Proteins/genetics ; Bacterial Proteins/metabolism ; Virulence Factors/genetics ; Virulence Factors/metabolism
    Chemical Substances Transcription Factors ; Bacterial Proteins ; Virulence Factors
    Language English
    Publishing date 2023-11-30
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, N.I.H., Extramural
    ZDB-ID 2968-3
    ISSN 1098-5530 ; 0021-9193
    ISSN (online) 1098-5530
    ISSN 0021-9193
    DOI 10.1128/jb.00226-23
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  3. Article ; Online: Site assessment survey to assess the impact of the COVID-19 pandemic on HIV clinic site services and strategies for mitigation in Washington, DC.

    Barish, Nicole / Barth, Shannon / Monroe, Anne K / Greenberg, Alan E / Castel, Amanda D

    BMC health services research

    2023  Volume 23, Issue 1, Page(s) 1130

    Abstract: ... status (n = 9), utilizing e-prescribing for auto refills even if the patient missed visits (n = 8), and ...

    Abstract Introduction: The COVID-19 pandemic has created substantial interruptions in healthcare presenting challenges for people with chronic illnesses to access care and treatment services. We aimed to assess the impact of the pandemic on HIV care delivery by characterizing the pandemic-related impact on HIV clinic-level services and the mitigation strategies that were developed to address them.
    Methods: The data comes from a site assessment survey conducted in the DC Cohort, an observational clinical cohort of PWH receiving care at 14 HIV outpatient clinics in Washington, D.C. Frequency counts and prevalence estimates of clinic-level survey responses about the impact of care delivery, COVID-19 testing, and vaccinations and mitigation strategies are presented.
    Results: Clinics reported an increase in temporary clinic closures (n = 2), reduction in clinic hours (n = 5), telehealth utilization (n = 10), adoption of multi-month dispensation of antiretroviral (ARV) medication (n = 11) and alternative drug delivery via postal/courier service, home/community delivery or pick-up (n = 11). Clinics utilized strategies for PWH who were lost to follow-up during the pandemic including offering care to persons with any income level and insurance status (n = 9), utilizing e-prescribing for auto refills even if the patient missed visits (n = 8), and utilization of the regional health information exchange to check for hospitalizations of PWH lost to follow-up (n = 8). Most social services offered before the pandemic remained available during the pandemic; however, some support services were modified.
    Conclusions: Our findings demonstrate the extent of pandemic-era disruptions and the use of clinic-level mitigation strategies among urban HIV clinics. These results may help prepare for future pandemic or public health emergencies that disrupt healthcare delivery and access.
    MeSH term(s) Humans ; COVID-19/epidemiology ; Pandemics ; District of Columbia/epidemiology ; COVID-19 Testing ; Delivery of Health Care ; HIV Infections/therapy ; HIV Infections/drug therapy
    Language English
    Publishing date 2023-10-20
    Publishing country England
    Document type Journal Article
    ZDB-ID 2050434-2
    ISSN 1472-6963 ; 1472-6963
    ISSN (online) 1472-6963
    ISSN 1472-6963
    DOI 10.1186/s12913-023-10069-7
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  4. Article ; Online: Impact of COVID-19 pandemic restrictions on community-dwelling caregivers and persons with dementia.

    Greenberg, Nicole E / Wallick, Amanda / Brown, Lisa M

    Psychological trauma : theory, research, practice and policy

    2020  Volume 12, Issue S1, Page(s) S220–S221

    Abstract: Restrictions related to the 2019 novel coronavirus (COVID-19) pose unique and significant challenges for community-dwelling caregivers and people with dementia, including disrupted routines, a lack of structure, decreased access to respite care, and new ... ...

    Abstract Restrictions related to the 2019 novel coronavirus (COVID-19) pose unique and significant challenges for community-dwelling caregivers and people with dementia, including disrupted routines, a lack of structure, decreased access to respite care, and new or worsening safety issues related to interpersonal violence and hygiene. In addition to identifying issues confronting caregivers, the authors also describe possible ways to address some of these pressing concerns. (PsycInfo Database Record (c) 2020 APA, all rights reserved).
    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; COVID-19 ; Caregivers/psychology ; Coronavirus Infections ; Dementia/nursing ; Dementia/psychology ; Humans ; Independent Living/psychology ; Infection Control ; Loneliness/psychology ; Middle Aged ; Pandemics ; Pneumonia, Viral ; Respite Care ; Social Isolation/psychology
    Keywords covid19
    Language English
    Publishing date 2020-06-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2497028-1
    ISSN 1942-969X ; 1942-9681
    ISSN (online) 1942-969X
    ISSN 1942-9681
    DOI 10.1037/tra0000793
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  5. Article ; Online: Interspecific variation in cooperative burrowing behavior by

    Bedford, Nicole L / Weber, Jesse N / Tong, Wenfei / Baier, Felix / Kam, Ariana / Greenberg, Rebecca A / Hoekstra, Hopi E

    Evolution letters

    2022  Volume 6, Issue 4, Page(s) 330–340

    Abstract: Animals often adjust their behavior according to social context, but the capacity for such behavioral flexibility can vary among species. Here, we test for interspecific variation in behavioral flexibility by comparing burrowing behavior across three ... ...

    Abstract Animals often adjust their behavior according to social context, but the capacity for such behavioral flexibility can vary among species. Here, we test for interspecific variation in behavioral flexibility by comparing burrowing behavior across three species of deer mice (genus
    Language English
    Publishing date 2022-07-22
    Publishing country England
    Document type Journal Article
    ISSN 2056-3744
    ISSN (online) 2056-3744
    DOI 10.1002/evl3.293
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  6. Article ; Online: Promoting Social and Emotional Learning in Middle School: Intervention Effects of Facing History and Ourselves.

    Domitrovich, Celene E / Harris, Alexis R / Syvertsen, Amy K / Morgan, Nicole / Jacobson, Linda / Cleveland, Michael / Moore, Julia E / Greenberg, Mark T

    Journal of youth and adolescence

    2022  Volume 51, Issue 7, Page(s) 1426–1441

    Abstract: There are fewer evidence-based social and emotional learning programs for middle school students compared to younger grades. This randomized controlled trial tests the effectiveness of Facing History and Ourselves (hereafter, Facing History) with a ... ...

    Abstract There are fewer evidence-based social and emotional learning programs for middle school students compared to younger grades. This randomized controlled trial tests the effectiveness of Facing History and Ourselves (hereafter, Facing History) with a sample of 694 (Facing History n = 437; Comparison n = 257) students from a low-resourced school district. Youth self-identified as female (59%), Black/African American (61%), Hispanic/Latinx (18%), White (2%), and multi-racial or some other race/ethnicity (19%). Intervention students perceived their classrooms as more caring and democratic than students in the comparison group. They reported higher levels of empathy, prosocial behavior, and stronger participatory citizenship beliefs. This study expands the evidence-based of effective SEL programs available to schools.
    MeSH term(s) Adolescent ; Emotions ; Female ; Hispanic or Latino ; Humans ; Racial Groups ; Schools ; Students/psychology
    Language English
    Publishing date 2022-03-22
    Publishing country United States
    Document type Journal Article ; Randomized Controlled Trial
    ZDB-ID 186743-x
    ISSN 1573-6601 ; 0047-2891
    ISSN (online) 1573-6601
    ISSN 0047-2891
    DOI 10.1007/s10964-022-01596-3
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    In stock of ZB MED Cologne/Königswinter

    Zs.B 3120: Show issues Location:
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  7. Article ; Online: Health Factors as Potential Mediators of the Longitudinal Effect of Loneliness on General Cognitive Ability.

    Kim, Alice J / Beam, Christopher R / Greenberg, Nicole E / Burke, Shanna L

    The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry

    2020  Volume 28, Issue 12, Page(s) 1272–1283

    Abstract: Objective: Higher levels of loneliness in older adulthood predict cognitive decline, but research on mediating mechanisms is sparse. We examine multisystemic physiological risk, functional ability, self-rated health, depressive symptoms, and social ... ...

    Abstract Objective: Higher levels of loneliness in older adulthood predict cognitive decline, but research on mediating mechanisms is sparse. We examine multisystemic physiological risk, functional ability, self-rated health, depressive symptoms, and social participation as mediating processes for the association between loneliness and general cognitive ability over a 10-year follow-up in an older adult sample.
    Methods: Three waves of data from 3,005 individuals (mean intake age: 69.30 (SD: 7.85) years; female = 51.61%) recruited during Wave 1 of the National Social Life, Health, and Aging Project were used to test whether hypothesized mediators collected at the 5-year follow-up explained effects of baseline loneliness on 10-year general cognitive ability.
    Results: The relationship between baseline loneliness and 10-year general cognitive ability was not mediated by multisystemic physiological risk. Functional ability (b = -0.24, SE = 0.05, p <0.001), self-rated health (b = -0.08, SE = 0.02, p <0.001), depressive symptoms (b= -0.20, SE = 0.05, p <0.001), and social participation (b = -0.03, SE = 0.01, p = 0.016) significantly mediated effects. Indirect effects remained significant after adjusting for demographic covariates and 5-year general cognitive ability, except social participation.
    Discussion: Loneliness may influence cognitive ability indirectly, signaling waning physical and psychiatric health more proximally correlated with cognitive ability. These mechanisms may serve as targets of intervention for cognitive maintenance in lonely older adults.
    MeSH term(s) Aged ; Aging ; Cognition ; Cognitive Dysfunction ; Female ; Humans ; Loneliness ; Longitudinal Studies
    Language English
    Publishing date 2020-08-11
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1278145-9
    ISSN 1545-7214 ; 1064-7481
    ISSN (online) 1545-7214
    ISSN 1064-7481
    DOI 10.1016/j.jagp.2020.07.017
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    Zs.A 4443: Show issues Location:
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  8. Article ; Online: Impact of COVID-19 pandemic restrictions on community-dwelling caregivers and persons with dementia.

    Greenberg, Nicole E. / Wallick, Amanda / Brown, Lisa M.

    Psychological Trauma: Theory, Research, Practice, and Policy

    2020  Volume 12, Issue S1, Page(s) S220–S221

    Keywords Clinical Psychology ; Social Psychology ; covid19
    Language English
    Publisher American Psychological Association (APA)
    Publishing country us
    Document type Article ; Online
    ZDB-ID 2497028-1
    ISSN 1942-969X ; 1942-9681
    ISSN (online) 1942-969X
    ISSN 1942-9681
    DOI 10.1037/tra0000793
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Evolution of the Quorum Sensing Regulon in Cooperating Populations of Pseudomonas aeruginosa.

    Smalley, Nicole E / Schaefer, Amy L / Asfahl, Kyle L / Perez, Crystal / Greenberg, E Peter / Dandekar, Ajai A

    mBio

    2022  Volume 13, Issue 1, Page(s) e0016122

    Abstract: In the opportunistic pathogenic bacterium Pseudomonas aeruginosa acyl-homoserine lactone quorum sensing (QS) can activate expression of dozens to hundreds of genes depending on the strain under investigation. Many QS-activated genes code for ... ...

    Abstract In the opportunistic pathogenic bacterium Pseudomonas aeruginosa acyl-homoserine lactone quorum sensing (QS) can activate expression of dozens to hundreds of genes depending on the strain under investigation. Many QS-activated genes code for extracellular products. P. aeruginosa has become a model for studies of cell-cell communication and coordination of cooperative activities, which result from production of extracellular products. We hypothesized that strain variation in the size of the QS regulon might reflect the environmental history of an isolate. We tested the hypothesis by performing long-term growth experiments with the well-studied strain PAO1, which has a relatively large QS regulon, under conditions where only limited QS-controlled functions are required. We grew P. aeruginosa for about 1000 generations in a condition where expression of QS-activated genes was required, and emergence of QS mutants was constrained and compared the QS regulons of populations after 35 generations to those after about 1000 generations in two independent lineages by using quorum quenching and RNA-seq technology. In one lineage the number of QS-activated genes identified was reduced by over 60% and in the other by about 30% in 1000-generation populations compared to 35-generation populations. Our results provide insight about the variations in the number of QS-activated genes reported for different P. aeruginosa environmental and clinical isolates and, about how environmental conditions might influence social evolution.
    MeSH term(s) Bacterial Proteins/genetics ; Bacterial Proteins/metabolism ; Gene Expression Regulation, Bacterial ; Pseudomonas aeruginosa/metabolism ; Quorum Sensing/genetics ; Regulon
    Chemical Substances Bacterial Proteins
    Language English
    Publishing date 2022-02-22
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, N.I.H., Intramural
    ZDB-ID 2557172-2
    ISSN 2150-7511 ; 2161-2129
    ISSN (online) 2150-7511
    ISSN 2161-2129
    DOI 10.1128/mbio.00161-22
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  10. Article: Impact of COVID-19 pandemic restrictions on community-dwelling caregivers and persons with dementia

    Greenberg, Nicole E / Wallick, Amanda / Brown, Lisa M

    Psychological trauma

    Abstract: Restrictions related to the 2019 novel coronavirus (COVID-19) pose unique and significant challenges for community-dwelling caregivers and people with dementia, including disrupted routines, a lack of structure, decreased access to respite care, and new ... ...

    Abstract Restrictions related to the 2019 novel coronavirus (COVID-19) pose unique and significant challenges for community-dwelling caregivers and people with dementia, including disrupted routines, a lack of structure, decreased access to respite care, and new or worsening safety issues related to interpersonal violence and hygiene. In addition to identifying issues confronting caregivers, the authors also describe possible ways to address some of these pressing concerns. (PsycInfo Database Record (c) 2020 APA, all rights reserved).
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #32584105
    Database COVID19

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