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  1. Article: Infrared Thermal Imaging for Evaluation of Clubfoot After the Ponseti Casting Method-An Exploratory Study.

    Ganesan, Balasankar / Yip, Joanne / Luximon, Ameersing / Gibbons, Paul J / Chivers, Alison / Balasankar, Suchita Kothe / Tong, Raymond Kai-Yu / Chai, Rifai / Al-Jumaily, Adel

    Frontiers in pediatrics

    2021  Volume 9, Page(s) 595506

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2021-04-20
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2711999-3
    ISSN 2296-2360
    ISSN 2296-2360
    DOI 10.3389/fped.2021.595506
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Recent Advances in the Production of Pharmaceuticals Using Selective Laser Sintering.

    Balasankar, Athinarayanan / Anbazhakan, Kandasamy / Arul, Velusamy / Mutharaian, Velankadu Natrayan / Sriram, Ganesan / Aruchamy, Kanakaraj / Oh, Tae Hwan / Ramasundaram, Subramaniyan

    Biomimetics (Basel, Switzerland)

    2023  Volume 8, Issue 4

    Abstract: Selective laser sintering (SLS) is an additive manufacturing process that has shown promise in the production of medical devices, including hip cups, knee trays, dental crowns, and hearing aids. SLS-based 3D-printed dosage forms have the potential to ... ...

    Abstract Selective laser sintering (SLS) is an additive manufacturing process that has shown promise in the production of medical devices, including hip cups, knee trays, dental crowns, and hearing aids. SLS-based 3D-printed dosage forms have the potential to revolutionise the production of personalised drugs. The ability to manipulate the porosity of printed materials is a particularly exciting aspect of SLS. Porous tablet formulations produced by SLS can disintegrate orally within seconds, which is challenging to achieve with traditional methods. SLS also enables the creation of amorphous solid dispersions in a single step, rather than the multi-step process required with conventional methods. This review provides an overview of 3D printing, describes the operating mechanism and necessary materials for SLS, and highlights recent advances in SLS for biomedical and pharmaceutical applications. Furthermore, an in-depth comparison and contrast of various 3D printing technologies for their effectiveness in tissue engineering applications is also presented in this review.
    Language English
    Publishing date 2023-07-27
    Publishing country Switzerland
    Document type Journal Article ; Review
    ISSN 2313-7673
    ISSN (online) 2313-7673
    DOI 10.3390/biomimetics8040330
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Ponseti method in the management of clubfoot under 2 years of age: A systematic review.

    Ganesan, Balasankar / Luximon, Ameersing / Al-Jumaily, Adel / Balasankar, Suchita Kothe / Naik, Ganesh R

    PloS one

    2017  Volume 12, Issue 6, Page(s) e0178299

    Abstract: Background: Congenital talipes equinovarus (CTEV), also known as clubfoot, is common congenital orthopedic foot deformity in children characterized by four components of foot deformities: hindfoot equinus, hindfoot varus, midfoot cavus, and forefoot ... ...

    Abstract Background: Congenital talipes equinovarus (CTEV), also known as clubfoot, is common congenital orthopedic foot deformity in children characterized by four components of foot deformities: hindfoot equinus, hindfoot varus, midfoot cavus, and forefoot adduction. Although a number of conservative and surgical methods have been proposed to correct the clubfoot deformity, the relapses of the clubfoot are not uncommon. Several previous literatures discussed about the technical details of Ponseti method, adherence of Ponseti protocol among walking age or older children. However there is a necessity to investigate the relapse pattern, compliance of bracing, number of casts used in treatment and the percentages of surgical referral under two years of age for clear understanding and better practice to achieve successful outcome without or reduce relapse. Therefore this study aims to review the current evidence of Ponseti method (manipulation, casting, percutaneous Achilles tenotomy, and bracing) in the management of clubfoot under two years of age.
    Materials and methods: Articles were searched from 2000 to 2015, in the following databases to identify the effectiveness of Ponseti method treatment for clubfoot: Medline, Cumulative Index to Nursing and Allied Health Literature (CINHAL), PubMed, and Scopus. The database searches were limited to articles published in English, and articles were focused on the effectiveness of Ponseti method on children with less than 2 years of age.
    Results: Of the outcome of 1095 articles from four electronic databases, twelve articles were included in the review. Pirani scoring system, Dimeglio scoring system, measuring the range of motion and rate of relapses were used as outcome measures.
    Conclusions: In conclusion, all reviewed, 12 articles reported that Ponseti method is a very effective method to correct the clubfoot deformities. However, we noticed that relapses occur in nine studies, which is due to the non-adherence of bracing regime and other factors such as low income and social economic status.
    MeSH term(s) Animals ; Clubfoot/surgery ; Disease Management ; Humans ; Orthopedic Procedures/methods
    Language English
    Publishing date 2017-06-20
    Publishing country United States
    Document type Journal Article ; Review ; Systematic Review
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0178299
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Current conservative management and classification of club foot: A review.

    Balasankar, Ganesan / Luximon, Ameersing / Al-Jumaily, Adel

    Journal of pediatric rehabilitation medicine

    2016  Volume 9, Issue 4, Page(s) 257–264

    Abstract: Clubfoot, known as congenital talipes equinovarus, is one of the complex paediatric foot deformity with the incidence of 1 in every 1000 live births. It consists of four complex foot abnormalities such as forefoot adductus, midfoot cavus, and hindfoot ... ...

    Abstract Clubfoot, known as congenital talipes equinovarus, is one of the complex paediatric foot deformity with the incidence of 1 in every 1000 live births. It consists of four complex foot abnormalities such as forefoot adductus, midfoot cavus, and hindfoot varus and ankle equinus. There are a number of surgical techniques (soft tissue releases, arthrodesis) used to correct clubfoot. However currently the conservative management (manipulation, serial casting, and braces) of clubfoot is considered as the best choice and it is widely accepted among orthopaedists. Clubfoot treated with surgical techniques might suffer various complications such as soft tissues contractures, neurovascular complications, infections, and shortening of the limbs. Although conservative method is generally considered as an effective method, it is still challenging to cure clubfoot in advance stages. Also, the classification of the initial severity of clubfoot is essential to evaluate the outcome of the treatment. In this review, the aim is to review the different types of conservative method and the assessment of clubfoot severity.
    Language English
    Publishing date 2016-11-30
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2403637-7
    ISSN 1875-8894 ; 1874-5393
    ISSN (online) 1875-8894
    ISSN 1874-5393
    DOI 10.3233/PRM-160394
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Developing a Three-Dimensional (3D) Assessment Method for Clubfoot-A Study Protocol.

    Ganesan, Balasankar / Luximon, Ameersing / Al-Jumaily, Adel A / Yip, Joanne / Gibbons, Paul J / Chivers, Alison

    Frontiers in physiology

    2018  Volume 8, Page(s) 1098

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2018-01-04
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2564217-0
    ISSN 1664-042X
    ISSN 1664-042X
    DOI 10.3389/fphys.2017.01098
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Impact of Coronavirus Disease 2019 (COVID-19) Outbreak Quarantine, Isolation, and Lockdown Policies on Mental Health and Suicide.

    Ganesan, Balasankar / Al-Jumaily, Adel / Fong, Kenneth N K / Prasad, Palak / Meena, Surendra Kumar / Tong, Raymond Kai-Yu

    Frontiers in psychiatry

    2021  Volume 12, Page(s) 565190

    Abstract: The novel coronavirus disease (COVID-19) pandemic has made a huge impact on people's physical and mental health, and it remains a cause of death for many all over the world. To prevent the spread of coronavirus infection, different types of public health ...

    Abstract The novel coronavirus disease (COVID-19) pandemic has made a huge impact on people's physical and mental health, and it remains a cause of death for many all over the world. To prevent the spread of coronavirus infection, different types of public health measures (social isolation, quarantine, lockdowns, and curfews) have been imposed by governments. However, mental health experts warn that the prolonged lockdown, quarantine, or isolation will create a "second pandemic" with severe mental health issues and suicides. The quarantined or isolated people may suffer from various issues such as physical inactivity, mental health, economic and social problems. As with the SARS outbreak in 2003, many suicide cases have been reported in connection with this current COVID-19 pandemic lockdown due to various factors such as social stigma, alcohol withdrawal syndrome, fear of COVID infection, loneliness, and other mental health issues. This paper provides an overview of risk factors that can cause suicide and outlines possible solutions to prevent suicide in this current COVID-19 pandemic.
    Language English
    Publishing date 2021-04-16
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2564218-2
    ISSN 1664-0640
    ISSN 1664-0640
    DOI 10.3389/fpsyt.2021.565190
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Ponseti method in the management of clubfoot under 2 years of age

    Balasankar Ganesan / Ameersing Luximon / Adel Al-Jumaily / Suchita Kothe Balasankar / Ganesh R Naik

    PLoS ONE, Vol 12, Iss 6, p e

    A systematic review.

    2017  Volume 0178299

    Abstract: BACKGROUND:Congenital talipes equinovarus (CTEV), also known as clubfoot, is common congenital orthopedic foot deformity in children characterized by four components of foot deformities: hindfoot equinus, hindfoot varus, midfoot cavus, and forefoot ... ...

    Abstract BACKGROUND:Congenital talipes equinovarus (CTEV), also known as clubfoot, is common congenital orthopedic foot deformity in children characterized by four components of foot deformities: hindfoot equinus, hindfoot varus, midfoot cavus, and forefoot adduction. Although a number of conservative and surgical methods have been proposed to correct the clubfoot deformity, the relapses of the clubfoot are not uncommon. Several previous literatures discussed about the technical details of Ponseti method, adherence of Ponseti protocol among walking age or older children. However there is a necessity to investigate the relapse pattern, compliance of bracing, number of casts used in treatment and the percentages of surgical referral under two years of age for clear understanding and better practice to achieve successful outcome without or reduce relapse. Therefore this study aims to review the current evidence of Ponseti method (manipulation, casting, percutaneous Achilles tenotomy, and bracing) in the management of clubfoot under two years of age. MATERIALS AND METHODS:Articles were searched from 2000 to 2015, in the following databases to identify the effectiveness of Ponseti method treatment for clubfoot: Medline, Cumulative Index to Nursing and Allied Health Literature (CINHAL), PubMed, and Scopus. The database searches were limited to articles published in English, and articles were focused on the effectiveness of Ponseti method on children with less than 2 years of age. RESULTS:Of the outcome of 1095 articles from four electronic databases, twelve articles were included in the review. Pirani scoring system, Dimeglio scoring system, measuring the range of motion and rate of relapses were used as outcome measures. CONCLUSIONS:In conclusion, all reviewed, 12 articles reported that Ponseti method is a very effective method to correct the clubfoot deformities. However, we noticed that relapses occur in nine studies, which is due to the non-adherence of bracing regime and other factors such as low income and social economic status.
    Keywords Medicine ; R ; Science ; Q
    Subject code 001
    Language English
    Publishing date 2017-01-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: A novel 3D evaluation method for assessing bone to bone relationships in clubfoot.

    Ganesan, B / Yip, J / Al-Jumaily, A / Fong, S S M / Kothe Balasankar, S / Ey Batlle, A M / Fong, K N K / Luximon, A

    European review for medical and pharmacological sciences

    2019  Volume 23, Issue 5, Page(s) 1882–1890

    Abstract: Objective: Clubfoot is a complex congenital three-dimensional foot deformity, which affects 150,000-200,000 newborn babies annually around the world. A good understanding of the alignment of the two osseous columns and the lower leg of the ankle and ... ...

    Abstract Objective: Clubfoot is a complex congenital three-dimensional foot deformity, which affects 150,000-200,000 newborn babies annually around the world. A good understanding of the alignment of the two osseous columns and the lower leg of the ankle and foot complex is essential for evaluating the severity of clubfoot. The purposes of this study were to (1) develop an automated three-dimensional (3D) surface model of severe clubfoot based on two-dimensional (2D) slices of computed tomography (CT) images, (2) evaluate the alignment of foot bones relative to the ankle in severe clubfoot, and (3) examine the structural changes in the shape of the clubfoot.
    Patients and methods: Two-dimensional CT image was taken from a four-year-old child with a severe clubfoot. Subsequently, an automated and detailed 3D surface model of the severe clubfoot was developed from the 2D images by using MATLAB software programming. Then, the x, y, and z coordinate angles were automatically calculated for each bone in the foot relative to the ankle (lower end of the tibia) to determine the orientations and relationships among the bones.
    Results: The relative position or orientation of each bone of the foot to the ankle of the severe clubfoot was objectively measured which was used to determine the orientation of each bone in the foot. Among the x, y, and z axes of the interested tarsal bones, the z axis represents the smallest moment of inertia, and the results showed that the bones in the x axis shifted medially with higher relative angle.
    Conclusions: This 3D objective measurement method for assessing clubfoot can be used to determine and classify the severity of clubfoot, as well as evaluate and monitor the progress of the clubfoot intervention based on the relative position of the tarsal bones. The method can also be used to quantify the relationship between the tarsal bones of the foot and lower end of the tibia. In addition, angular measurements can be used to assess other pathological conditions of the foot such as pes cavus and pes planus.
    MeSH term(s) Ankle/diagnostic imaging ; Child, Preschool ; Clubfoot/diagnostic imaging ; Foot/diagnostic imaging ; Humans ; Image Interpretation, Computer-Assisted ; Imaging, Three-Dimensional/methods ; Male ; Models, Anatomic ; Tibia/diagnostic imaging ; Toe Phalanges/diagnostic imaging ; Tomography, X-Ray Computed/methods
    Language English
    Publishing date 2019-03-23
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 605550-3
    ISSN 2284-0729 ; 1128-3602 ; 0392-291X
    ISSN (online) 2284-0729
    ISSN 1128-3602 ; 0392-291X
    DOI 10.26355/eurrev_201903_17225
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Balance control, agility, eye-hand coordination, and sport performance of amateur badminton players: A cross-sectional study.

    Wong, Towel K K / Ma, Ada W W / Liu, Karen P Y / Chung, Louisa M Y / Bae, Young-Hyeon / Fong, Shirley S M / Ganesan, Balasankar / Wang, Hsing-Kuo

    Medicine

    2019  Volume 98, Issue 2, Page(s) e14134

    Abstract: In this study, balance performance, agility, eye-hand coordination, and sports performance were compared between amateur badminton players and active controls.Thirty young adult badminton players and 33 active controls participated in the study. Static ... ...

    Abstract In this study, balance performance, agility, eye-hand coordination, and sports performance were compared between amateur badminton players and active controls.Thirty young adult badminton players and 33 active controls participated in the study. Static single-leg standing balance (with eyes closed) was measured using a force platform, and dynamic balance was measured using the Y Balance Test (lower quarter). Agility was measured using a hexagon agility test, and eye-hand coordination was measured using a computerized finger-pointing task. Sports performance was quantified by the number of times a shuttlecock fell in a designated area following a badminton serve.The badminton players had superior accuracy in badminton serving (P < .001) relative to the active controls. However, no significant between-group differences were noted in all other outcome variables (P > .05).Amateur badminton players had more favorable sports performance, but not balance performance, agility, or eye-hand coordination, than controls.
    MeSH term(s) Adult ; Athletic Performance/physiology ; Case-Control Studies ; Cross-Sectional Studies ; Female ; Healthy Volunteers ; Humans ; Male ; Movement/physiology ; Postural Balance/physiology ; Psychomotor Performance/physiology ; Racquet Sports/physiology
    Language English
    Publishing date 2019-01-11
    Publishing country United States
    Document type Journal Article ; Observational Study
    ZDB-ID 80184-7
    ISSN 1536-5964 ; 0025-7974
    ISSN (online) 1536-5964
    ISSN 0025-7974
    DOI 10.1097/MD.0000000000014134
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Chinese Martial Art Training Failed to Improve Balance or Inhibit Falls in Older Adults.

    Ma, Ada W W / Wang, Hsing-Kuo / Chen, Duan-Rung / Chen, Ya-Mei / Chak, Yvonne T C / Chan, Joan W Y / Yam, Timothy T T / Cheng, Yoyo T Y / Ganesan, Balasankar / Fong, Shirley S M

    Perceptual and motor skills

    2019  Volume 126, Issue 3, Page(s) 389–409

    Abstract: This randomized controlled trial explored the effects of a Ving Tsun (VT) Chinese martial art training program on reactive standing balance performance, postural muscle reflex contraction latency, leg muscle performance, balance confidence and falls in ... ...

    Abstract This randomized controlled trial explored the effects of a Ving Tsun (VT) Chinese martial art training program on reactive standing balance performance, postural muscle reflex contraction latency, leg muscle performance, balance confidence and falls in community-dwelling older adults. We randomly assigned 33 healthy older adults to either a VT group (mean age = 67.5 years) or a control group (mean age = 72.1 years). The VT group received two 1-hour VT training sessions per week for three months (24 sessions). Primary outcome measures collected before and after the intervention period were electromyographic muscle activation onset latencies of the hamstring and gastrocnemius and the center of pressure path, length and movement velocity in standing (reactive balance performance). Secondary outcome measures included isometric peak force and time to isometric peak force of the knee extensors and flexors, the Activities-Specific Balance Confidence Scale score, and fall history. Results revealed that the mean gastrocnemius muscle activation onset latency was significantly longer (22.53 ms) in the VT group after the intervention. The peak force of the knee flexors significantly increased (by 1.58 kg) in the control group over time but not in the VT group. The time to reach peak force in the knee flexors was significantly longer (by 0.51 s) in the control group (but not the VT group) at posttest compared with the pretest value. No other significant group, time, or group-by-time interaction effects were noted. We discussed possible reasons for the failure of three months of martial art training to benefit fall risks among these older adults.
    MeSH term(s) Accidental Falls/prevention & control ; Aged ; Aging/physiology ; Exercise Therapy/methods ; Female ; Humans ; Leg/physiology ; Male ; Martial Arts ; Middle Aged ; Muscle, Skeletal/physiology ; Postural Balance/physiology ; Treatment Failure
    Language English
    Publishing date 2019-02-25
    Publishing country United States
    Document type Journal Article ; Randomized Controlled Trial
    ZDB-ID 204507-2
    ISSN 1558-688X ; 0031-5125
    ISSN (online) 1558-688X
    ISSN 0031-5125
    DOI 10.1177/0031512518824945
    Database MEDical Literature Analysis and Retrieval System OnLINE

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