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  1. Article ; Online: Stent in Coronary Bifurcation: Newer Better Than Older? Not Good Enough for Left Main Yet.

    Frankie Tam, Chor-Cheung

    JACC. Asia

    2021  Volume 1, Issue 1, Page(s) 80–81

    Language English
    Publishing date 2021-06-15
    Publishing country United States
    Document type Editorial
    ISSN 2772-3747
    ISSN (online) 2772-3747
    DOI 10.1016/j.jacasi.2021.05.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: COVID-19 and Acute Coronary Syndrome

    Chor-Cheung Frankie TAM / David SIU / Hung Fat TSE

    The Lancet Regional Health. Western Pacific, Vol 19, Iss , Pp 100346- (2022)

    Lessons for Everyone

    2022  

    Keywords Public aspects of medicine ; RA1-1270
    Language English
    Publishing date 2022-02-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: COVID-19 and Acute Coronary Syndrome: Lessons for Everyone.

    Tam, Chor-Cheung Frankie / Siu, David / Tse, Hung Fat

    The Lancet regional health. Western Pacific

    2021  Volume 19, Page(s) 100346

    Language English
    Publishing date 2021-12-22
    Publishing country England
    Document type Journal Article
    ISSN 2666-6065
    ISSN (online) 2666-6065
    DOI 10.1016/j.lanwpc.2021.100346
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Intravascular Lithotripsy on Concentric, Eccentric, and Extrastent Calcium: Insights From a Bench Test Model.

    Tam, Chor-Cheung Frankie / Leung, Man-Fai Matthew / Fang, Christian

    JACC. Basic to translational science

    2021  Volume 6, Issue 11, Page(s) 885–886

    Language English
    Publishing date 2021-11-22
    Publishing country United States
    Document type Journal Article
    ISSN 2452-302X
    ISSN (online) 2452-302X
    DOI 10.1016/j.jacbts.2021.08.008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Coronary Intravascular Lithotripsy in a Tight Circumferential Calcified Lesion in the Presence of Haematoma Extending into Left Main Coronary Artery After Rotational Atherectomy.

    Fang, Jonathan Xinguo / Yung, Arthur Sze-Yue / Lam, Simon Cheung-Chi / Tam, Frankie Chor-Cheung

    Interventional cardiology (London, England)

    2022  Volume 17, Page(s) e12

    Abstract: Calcified disease increases procedural challenges and is associated with worse outcomes in percutaneous coronary intervention. Coronary intravascular lithotripsy is a new balloon-based modality for treating calcified disease with deep circumferential ... ...

    Abstract Calcified disease increases procedural challenges and is associated with worse outcomes in percutaneous coronary intervention. Coronary intravascular lithotripsy is a new balloon-based modality for treating calcified disease with deep circumferential calcification. Its main benefit is simplicity and safety compared to atherectomy. However, atherectomy remains the modality of choice in balloon-uncrossable lesions. More than one modality is often needed for treatment of calcified disease. The authors present a case of a balloon-uncrossable calcified ostial left circumflex lesion which was first treated with rotational atherectomy. However, there was haematoma formation in the ostial circumflex extending into left main coronary artery, together with suboptimal preparation of calcified disease. Intravascular coronary lithotripsy was then used to successfully prepare the calcified lesion for stenting without causing extension of the haematoma.
    Language English
    Publishing date 2022-09-23
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2813989-6
    ISSN 1756-1485 ; 1756-1485
    ISSN (online) 1756-1485
    ISSN 1756-1485
    DOI 10.15420/icr.2021.18
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Challenges in management of ST elevation myocardial infarction during COVID-19 pandemic.

    Tam, Chor-Cheung Frankie / Siu, Chung-Wah David / Tse, Hung Fat

    Cardiology plus

    2021  Volume 6, Issue 4, Page(s) 218–230

    Abstract: The coronavirus disease-2019 (COVID-19) pandemic has brought unprecedented changes to our world and health-care system. Its high virulence and infectiousness directly infect people's respiratory system and indirectly disrupt our health-care ... ...

    Abstract The coronavirus disease-2019 (COVID-19) pandemic has brought unprecedented changes to our world and health-care system. Its high virulence and infectiousness directly infect people's respiratory system and indirectly disrupt our health-care infrastructure. In particular, ST elevation myocardial infarction (STEMI) is a clinical emergency emphasizes on the establishment of care system to minimize delay to reperfusion. As such, the impact of COVID-19 on STEMI care, ranging from disease severity, patient delay, diagnostic difficulty, triage to selection of reperfusion strategy and postoperative care, is immense. Importantly, not only we have to save our patients, but we must also need to protect all health-care workers and prevent environmental contamination. Otherwise, in-hospital transmission can quickly evolve into nosocomial outbreak with staff infection and quarantine which lead to health-care system collapse. In this article, we will discuss the challenges in various aspects of STEMI management during COVID-19, as well as the mitigation measures we can take to optimize outcome and our future.
    Language English
    Publishing date 2021-12-30
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2987027-6
    ISSN 2470-752X ; 2470-7511
    ISSN (online) 2470-752X
    ISSN 2470-7511
    DOI 10.4103/2470-7511.334400
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: First-in-Human Undermining Iatrogenic Coronary Obstruction With Radiofrequency Needle (UNICORN) Procedure During Valve-in-Valve Transcatheter Aortic Valve Replacement.

    Chan, Kwong-Yue Eric / Tai-Leung Chan, Daniel / Lam, Cheung-Chi Simon / Shu-Yue Sze, Michael / Un, Ka-Chun / Tam, Chor-Cheung Frankie / Lam, Yui-Ming / Wong, Chun-Ka

    Circulation. Cardiovascular interventions

    2022  Volume 15, Issue 11, Page(s) 928–931

    MeSH term(s) Humans ; Transcatheter Aortic Valve Replacement/adverse effects ; Transcatheter Aortic Valve Replacement/methods ; Treatment Outcome ; Heart Valve Prosthesis ; Aortic Valve Stenosis/diagnostic imaging ; Aortic Valve Stenosis/surgery ; Coronary Occlusion/diagnostic imaging ; Coronary Occlusion/etiology ; Coronary Occlusion/therapy ; Iatrogenic Disease ; Aortic Valve/diagnostic imaging ; Aortic Valve/surgery ; Prosthesis Design
    Language English
    Publishing date 2022-10-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2450797-0
    ISSN 1941-7632 ; 1941-7640
    ISSN (online) 1941-7632
    ISSN 1941-7640
    DOI 10.1161/CIRCINTERVENTIONS.122.012399
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Advances in technology and techniques for transcatheter aortic valve replacement with concomitant peripheral arterial disease.

    Wong, Chun-Ka / Chiu, Alston Conrad Ho-On / Chan, Kwong-Yue Eric / Sze, Shu-Yue / Tam, Frankie Chor-Cheung / Un, Ka-Chun / Lam, Simon Cheung-Chi / Tse, Hung-Fat

    Frontiers in medical technology

    2022  Volume 4, Page(s) 959249

    Abstract: Aortic stenosis (AS) is a prevalent disease affecting 3.7% of the adult population aged 65 or above. In the past, surgical aortic valve replacement (SAVR) was the only definitive therapy available for the treatment of severe AS. Owing to the invasive ... ...

    Abstract Aortic stenosis (AS) is a prevalent disease affecting 3.7% of the adult population aged 65 or above. In the past, surgical aortic valve replacement (SAVR) was the only definitive therapy available for the treatment of severe AS. Owing to the invasive nature of open-heart surgery, patients with advanced age and frailty could not benefit from SAVR. The advent of transcatheter aortic valve replacement (TAVR) in the past decade has offered an alternative treatment option for patients with severe AS, particularly those who are deemed to have high surgical risks. Nevertheless, a large proportion of patients also have concomitant peripheral arterial disease (PAD), which increases the risk of peri-procedural vascular complication, and precludes the possibility of transfemoral TAVR owing to inadequate luminal size for delivery system deployment. In this review, the prevalence and outcome of TAVR patients with PAD will be discussed. Furthermore, novel technologies and techniques that enable TAVR to be safely performed using transfemoral or alternative access in patients with severe PAD will be reviewed.
    Language English
    Publishing date 2022-08-18
    Publishing country Switzerland
    Document type Journal Article ; Review
    ISSN 2673-3129
    ISSN (online) 2673-3129
    DOI 10.3389/fmedt.2022.959249
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Multi-Omics Signatures Link to Ticagrelor Effects on Vascular Function in Patients With Acute Coronary Syndrome.

    Tam, Chor-Cheung Frankie / Chan, Yap-Hang / Wong, Yuen-Kwun / Li, Zhen / Zhu, Xiurui / Su, Kuo-Jung / Ganguly, Anindita / Hwa, Kuoyuan / Ling, Xuefeng B / Tse, Hung-Fat

    Arteriosclerosis, thrombosis, and vascular biology

    2022  Volume 42, Issue 6, Page(s) 789–798

    Abstract: Background: Long-term antiplatelet agents including the potent P2Y12 antagonist ticagrelor are indicated in patients with a previous history of acute coronary syndrome. We sought to compare the effect of ticagrelor with that of aspirin monotherapy on ... ...

    Abstract Background: Long-term antiplatelet agents including the potent P2Y12 antagonist ticagrelor are indicated in patients with a previous history of acute coronary syndrome. We sought to compare the effect of ticagrelor with that of aspirin monotherapy on vascular endothelial function in patients with prior acute coronary syndrome.
    Methods: This was a prospective, single center, parallel group, investigator-blinded randomized controlled trial. We randomized 200 patients on long-term aspirin monotherapy with prior acute coronary syndrome in a 1:1 fashion to receive ticagrelor 60 mg BD (n=100) or aspirin 100 mg OD (n=100). The primary end point was change from baseline in brachial artery flow-mediated dilation at 12 weeks. Secondary end points were changes to platelet activation marker (CD41_62p) and endothelial progenitor cell (CD34/133) count measured by flow cytometry, plasma level of adenosine, IL-6 (interleukin-6) and EGF (epidermal growth factor), and multi-omics profiling at 12 weeks.
    Results: After 12 weeks, brachial flow-mediated dilation was significantly increased in the ticagrelor group compared with the aspirin group (ticagrelor: 3.48±3.48% versus aspirin: -1.26±2.85%, treatment effect 4.73 [95% CI, 3.85-5.62],
    Conclusions: In patients with prior acute coronary syndrome, ticagrelor 60 mg BD monotherapy significantly improved brachial flow-mediated dilation compared with aspirin monotherapy and was associated with significant changes in metabolomic and lipidomic signatures.
    Registration: URL: https://www.
    Clinicaltrials: gov; Unique identifier: NCT03881943.
    MeSH term(s) Acute Coronary Syndrome ; Adenosine/adverse effects ; Aspirin/adverse effects ; Epidermal Growth Factor ; Humans ; Interleukin-6 ; Percutaneous Coronary Intervention ; Platelet Aggregation Inhibitors/adverse effects ; Prospective Studies ; Ticagrelor/adverse effects ; Treatment Outcome
    Chemical Substances Interleukin-6 ; Platelet Aggregation Inhibitors ; Epidermal Growth Factor (62229-50-9) ; Ticagrelor (GLH0314RVC) ; Adenosine (K72T3FS567) ; Aspirin (R16CO5Y76E)
    Language English
    Publishing date 2022-04-07
    Publishing country United States
    Document type Journal Article ; Randomized Controlled Trial ; Research Support, Non-U.S. Gov't
    ZDB-ID 1221433-4
    ISSN 1524-4636 ; 1079-5642
    ISSN (online) 1524-4636
    ISSN 1079-5642
    DOI 10.1161/ATVBAHA.121.317513
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Impact of Coronavirus Disease 2019 (COVID-19) Outbreak on ST-Segment-Elevation Myocardial Infarction Care in Hong Kong, China.

    Tam, Chor-Cheung Frankie / Cheung, Kent-Shek / Lam, Simon / Wong, Anthony / Yung, Arthur / Sze, Michael / Lam, Yui-Ming / Chan, Carmen / Tsang, Tat-Chi / Tsui, Matthew / Tse, Hung-Fat / Siu, Chung-Wah

    Circulation. Cardiovascular quality and outcomes

    2020  Volume 13, Issue 4, Page(s) e006631

    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections/complications ; Coronavirus Infections/epidemiology ; Disease Outbreaks ; Hong Kong ; Humans ; Pandemics ; Pneumonia, Viral/complications ; Pneumonia, Viral/epidemiology ; SARS-CoV-2 ; ST Elevation Myocardial Infarction/complications ; ST Elevation Myocardial Infarction/therapy ; Time-to-Treatment
    Keywords covid19
    Language English
    Publishing date 2020-03-17
    Publishing country United States
    Document type Letter
    ZDB-ID 2483197-9
    ISSN 1941-7705 ; 1941-7713
    ISSN (online) 1941-7705
    ISSN 1941-7713
    DOI 10.1161/CIRCOUTCOMES.120.006631
    Database MEDical Literature Analysis and Retrieval System OnLINE

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