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  1. Article ; Online: Stratifying nursing home care to further explore a locally validated risk factor for community-acquired pneumonia (SNAP-CAP Study).

    Kutsar, Dennis / Awad, Nirvana / Rastogi, Rupangi

    Antimicrobial stewardship & healthcare epidemiology : ASHE

    2023  Volume 3, Issue 1, Page(s) e191

    Abstract: We observed that patients admitted to our hospital from a prestratified group of congregated living facilities had a numerically higher percentage of study-defined resistant organisms in sputum cultures compared to facilities without these ... ...

    Abstract We observed that patients admitted to our hospital from a prestratified group of congregated living facilities had a numerically higher percentage of study-defined resistant organisms in sputum cultures compared to facilities without these characteristics [89.4% vs 78.3%, odds ratio [OR] = 2.34 (95% CI, 0.73-7.58)].
    Language English
    Publishing date 2023-10-27
    Publishing country England
    Document type Journal Article
    ISSN 2732-494X
    ISSN (online) 2732-494X
    DOI 10.1017/ash.2023.466
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Treatment of unexplained coma and hypokinetic-rigid syndrome in a patient with COVID-19.

    Roy, Devjit / Song, Justin / Awad, Nirvana / Zamudio, Paul

    BMJ case reports

    2021  Volume 14, Issue 3

    Abstract: The COVID-19 pandemic has dealt a devastating blow to healthcare systems globally. Approximately 3.2% of patients infected with COVID-19 require invasive ventilation during the course of the illness. Within this population, 25% of patients are affected ... ...

    Abstract The COVID-19 pandemic has dealt a devastating blow to healthcare systems globally. Approximately 3.2% of patients infected with COVID-19 require invasive ventilation during the course of the illness. Within this population, 25% of patients are affected with neurological manifestations. Among those who are affected by severe neurological manifestations, some may have acute cerebrovascular complications (5%), impaired consciousness (15%) or exhibit skeletal muscle hypokinesis (20%). The cause of the severe cognitive impairment and hypokinesis is unknown at this time. Potential causes include COVID-19 viral encephalopathy, toxic metabolic encephalopathy, post-intensive care unit syndrome and cerebrovascular pathology. We present a case of a 60 year old patient who sustained a prolonged hospitalization with COVID-19, had a cerebrovascular event and developed a persistent unexplained encephalopathy along with a hypokinetic state. He was treated successfully with modafinil and carbidopa/levodopa showing clinical improvement within 3-7 days and ultimately was able to successfully discharge home.
    MeSH term(s) Blood Coagulation ; Brain Diseases/physiopathology ; Brain Diseases/virology ; COVID-19/blood ; COVID-19/complications ; COVID-19/physiopathology ; COVID-19/therapy ; Carbidopa/administration & dosage ; Central Nervous System Stimulants/administration & dosage ; Cognitive Dysfunction/diagnosis ; Cognitive Dysfunction/etiology ; Critical Care/methods ; Drug Combinations ; Humans ; Hypokinesia/diagnosis ; Hypokinesia/etiology ; Hypokinesia/therapy ; Ischemic Stroke/diagnostic imaging ; Ischemic Stroke/etiology ; Ischemic Stroke/physiopathology ; Ischemic Stroke/therapy ; Levodopa/administration & dosage ; Magnetic Resonance Imaging/methods ; Male ; Middle Aged ; Modafinil/administration & dosage ; Rehabilitation/methods ; Respiration, Artificial/methods ; SARS-CoV-2/isolation & purification ; Severity of Illness Index ; Treatment Outcome ; Ventilator Weaning/methods
    Chemical Substances Central Nervous System Stimulants ; Drug Combinations ; carbidopa, levodopa drug combination ; Levodopa (46627O600J) ; Carbidopa (MNX7R8C5VO) ; Modafinil (R3UK8X3U3D)
    Language English
    Publishing date 2021-03-02
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2020-239781
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Withdrawn as duplicate: COVID-19 pandemic planning, response, and lessons learned at a community hospital.

    Schiller, Daryl S / Fulman, Magda / Champagne, Jennifer / Awad, Nirvana

    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists

    2020  Volume 79, Issue 9, Page(s) e154

    Keywords covid19
    Language English
    Publishing date 2020-09-29
    Publishing country England
    Document type Retraction of Publication
    ZDB-ID 1224627-x
    ISSN 1535-2900 ; 1079-2082
    ISSN (online) 1535-2900
    ISSN 1079-2082
    DOI 10.1093/ajhp/zxaa298
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 419: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
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  4. Article ; Online: Impact of hydroxychloroquine on disease progression and ICU admissions in patients with SARS-CoV-2 infection.

    Awad, Nirvana / Schiller, Daryl S / Fulman, Magda / Chak, Azfar

    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists

    2021  Volume 78, Issue 8, Page(s) 689–696

    Abstract: Purpose: To evaluate whether use of hydroxychloroquine was associated with a reduced likelihood of intensive care unit (ICU) admission in patients with coronavirus disease 2019 (COVID-19) in the early weeks of the pandemic.: Methods: A retrospective, ...

    Abstract Purpose: To evaluate whether use of hydroxychloroquine was associated with a reduced likelihood of intensive care unit (ICU) admission in patients with coronavirus disease 2019 (COVID-19) in the early weeks of the pandemic.
    Methods: A retrospective, observational cohort study was conducted to determine selected treatment outcomes in 336 patients hospitalized with COVID-19 at an acute care community hospital in the Hudson Valley region of New York from March 20 to April 20, 2020. Eligibility included admission to the hospital, a laboratory-confirmed diagnosis of SARS-CoV-2 infection, and no need for intubation or intensive care at admission. The median (interquartile range) ages of patients who received hydroxychloroquine (n = 188) and those who did not (n = 148) were 68 (58-82) and 64 (51-73) years, respectively. In a multivariable model that included age, gender, obesity, diabetes, and hydroxychloroquine use, patients who received hydroxychloroquine were significantly more likely than those not treated with the drug to be transferred to an ICU (odds ratio, [OR], 8.1; 95% confidence interval [CI]: 3.8-17) and significantly more likely to be intubated (OR, 7.99; 95% CI, 3.76-16.91); these associations were not influenced by disease severity. In-hospital mortality did not differ significantly with disease severity between those who did and those who did not receive hydroxychloroquine.
    Conclusion: Hydroxychloroquine use was significantly associated with increased risks of ICU admission and intubation in patients with mild, moderate, and severe symptoms of COVID-19. There were no significant between-group differences in mortality with use vs nonuse of hydroxychloroquine.
    MeSH term(s) Adolescent ; Adult ; Aged ; Aged, 80 and over ; COVID-19/drug therapy ; COVID-19/mortality ; Cohort Studies ; Disease Progression ; Female ; Humans ; Hydroxychloroquine/administration & dosage ; Hydroxychloroquine/therapeutic use ; Intensive Care Units ; Length of Stay ; Male ; Middle Aged ; New York ; Patient Admission ; Retrospective Studies ; SARS-CoV-2 ; Survival Analysis ; Young Adult
    Chemical Substances Hydroxychloroquine (4QWG6N8QKH)
    Language English
    Publishing date 2021-03-17
    Publishing country England
    Document type Journal Article ; Observational Study
    ZDB-ID 1224627-x
    ISSN 1535-2900 ; 1079-2082
    ISSN (online) 1535-2900
    ISSN 1079-2082
    DOI 10.1093/ajhp/zxab056
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 419: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article ; Online: COVID-19 pandemic planning, response, and lessons learned at a community hospital.

    Schiller, Daryl S / Fulman, Magda / Champagne, Jennifer / Awad, Nirvana

    publication RETRACTED

    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists

    2020  Volume 77, Issue 17, Page(s) 1371–1374

    MeSH term(s) COVID-19 ; Civil Defense ; Coronavirus Infections ; Health Planning ; Hospitals, Community/organization & administration ; Humans ; Medication Systems, Hospital/organization & administration ; Off-Label Use ; Pandemics ; Personnel Staffing and Scheduling ; Pharmacists ; Pharmacy Service, Hospital/organization & administration ; Pneumonia, Viral
    Keywords covid19
    Language English
    Publishing date 2020-05-11
    Publishing country England
    Document type Journal Article ; Retracted Publication
    ZDB-ID 1224627-x
    ISSN 1535-2900 ; 1079-2082
    ISSN (online) 1535-2900
    ISSN 1079-2082
    DOI 10.1093/ajhp/zxaa179
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 419: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Article ; Online: COVID-19 pandemic planning, response, and lessons learned at a community hospital

    Schiller, Daryl S / Fulman, Magda / Champagne, Jennifer / Awad, Nirvana

    American Journal of Health-System Pharmacy ; ISSN 1079-2082 1535-2900

    2020  

    Keywords Health Policy ; Pharmacology ; covid19
    Language English
    Publisher Oxford University Press (OUP)
    Publishing country uk
    Document type Article ; Online
    DOI 10.1093/ajhp/zxaa298
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: COVID-19 pandemic planning, response, and lessons learned at a community hospital

    Schiller, Daryl S / Fulman, Magda / Champagne, Jennifer / Awad, Nirvana

    American Journal of Health-System Pharmacy

    2020  Volume 77, Issue 17, Page(s) 1371–1374

    Keywords Health Policy ; Pharmacology ; covid19
    Language English
    Publisher Oxford University Press (OUP)
    Publishing country uk
    Document type Article ; Online
    ZDB-ID 1224627-x
    ISSN 1079-2082
    ISSN 1079-2082
    DOI 10.1093/ajhp/zxaa179
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 419: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

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